Phase III ASCENT Study of Metastatic TNBC Halted Due to Compelling Efficacy
The decision to halt the study was based on the unanimous recommendation by an independent data safety monitoring committee during its routine review of the ASCENT study. (Source: CancerNetwork)
Source: CancerNetwork - April 10, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Moving toward Nonchemotherapy-Based Approaches in Follicular Lymphoma
Michael L. Grossbard, MD, suggested that chemo-free regimens, including PI3K inhibitors and a more widespread use of allogeneic stem cell transplant, are being explored as treatment options in this space. (Source: CancerNetwork)
Source: CancerNetwork - April 9, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Case Study Shows Efficacy from Tocilizumab in Patient With COVID-19, Myeloma
A case study of a patient in Wuhan, China demonstrated that tocilizumab may be an effective treatment for very ill patients with COVID-19 who also have multiple myeloma and other blood cancers. (Source: CancerNetwork)
Source: CancerNetwork - April 9, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
FDA Approves Encorafenib Plus Cetuximab for Metastatic CRC with BRAF V600E Mutation
The FDA approved the combination use of encorafenib and cetuximab for the treatment of adult patients with BRAFV600E-positive metastatic colorectal cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 9, 2020 Category: Cancer & Oncology Authors: Kristie L. Kahl Source Type: news
Phase II Trial of Leronlimab for COVID-19 Enrolls First Patients
CytoDyn announced that it has enrolled and treated the first 2 patients with COVID-19 with leronlimab under its phase II randomized clinical trial. (Source: CancerNetwork)
Source: CancerNetwork - April 9, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Measures Taken During COVID-19 Pandemic for Patients with Cancer in China
In an editorial, researchers discussed active and effective measures for the care of patients with cancer during the coronavirus disease 2019 (COVID-19) in China. (Source: CancerNetwork)
Source: CancerNetwork - April 8, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Researchers Plan to Evaluate CORVax12 Vaccine in Phase I Clinical Trial for COVID-19
Providence Cancer Institute at Providence St. Joseph Health is pursuing a first-in-human phase I clinical trial of CORVax12, which is intended to act as a prophylactic vaccine to prevent COVID-19. (Source: CancerNetwork)
Source: CancerNetwork - April 8, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Research Suggests Liver Cancer Prevention Strategy Should Include NASH, Elderly Patients
In a recent study, researchers indicated that primary liver cancer prevention schedules should give more attention to nonalcoholic steatohepatitis and elderly patients. (Source: CancerNetwork)
Source: CancerNetwork - April 8, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
FDA Grants Priority Review to Nivolumab Plus Ipilimumab to Treat NSCLC
Bristol Myers Squibb recently announced that the FDA granted priority review to nivolumab plus ipilimumab in combination with chemotherapy as a first-line treatment for metastatic NSCLC. (Source: CancerNetwork)
Source: CancerNetwork - April 8, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news
Planned Phase III Trial of Ruxolitinib Plus Standard-of-Care for Patients with COVID-19
Incyte announced that they are working with the FDA to initiate a phase III clinical trial to assess ruxolitinib (Jakafi) plus standard-of-care in patients with coronavirus disease 2019 (COVID-19) induced cytokine storm. (Source: CancerNetwork)
Source: CancerNetwork - April 7, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Study Highlights Need for Female Representation in Oncology Research
Despite positive trends, researchers found that substantial differences in the representation of gender in oncology publications by author role, article type, citation count, and credentials persist. (Source: CancerNetwork)
Source: CancerNetwork - April 7, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Patients of Metastatic Prostate Cancer Could Benefit from Immunotherapy Treatment
A recent study found that a group of patients with metastatic castration-resistant prostate cancer responded positively to treatment with ipilimumab, prolonging survival after treatment in the “favorable” cohort. (Source: CancerNetwork)
Source: CancerNetwork - April 7, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news
FDA Grants Priority Review to Pembrolizumab Monotherapy for TMB-High Tumors
The FDA granted priority review to pembrolizumab monotherapy for the treatment of adult and pediatric patients with unresectable or metastatic TMB-high solid tumors who have progressed following prior treatment and who have no satisfactory alternative treatment options. (Source: CancerNetwork)
Source: CancerNetwork - April 7, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Phase II ZUMA-2 Study Shows Promising Safety and Efficacy Results for KTE-X19
A 1-year follow-up of the phase II ZUMA-2 study found that KTE-X19 induced durable remissions in a majority of patients with relapsed or refractory mantle-cell lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - April 6, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news
Managing Treatment for Patients with Prostate Cancer During the COVID-19 Pandemic
An international team of researchers created a framework of recommendations to help patients and healthcare professionals make decisions regarding radiation treatment for patients with prostate cancer during the COVID-19 pandemic. (Source: CancerNetwork)
Source: CancerNetwork - April 6, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news
