Topical application of lyophilized and powdered human amniotic membrane promotes diabetic ulcer healing
ConclusionsAMX ameliorated pain and extent of a chronic diabetic ulcer. The effect could be ascribed to angiogenesis and epithelium stimulation that was confirmed in in vitro. Multiple wound healing-involved proteins were detected but further studies are needed to assess their specific role. (Source: Wound Medicine)
Source: Wound Medicine - August 11, 2019 Category: General Medicine Source Type: research

Best practice recommendations for silver wound dressings: Results of an expert survey aiming to reach a consensus
Publication date: Available online 5 August 2019Source: Wound MedicineAuthor(s): J G Böttrich, H Braunwarth, J Dissemond, K C Münter, F Schümmelfeder, P WilkenZusammenfassungAkute und chronische Wunden mit lokalen Infektionszeichen oder einer kritischen Kolonisation stellen in der Versorgung eine interdisziplinäre und interprofessionelle Herausforderung in der Medizin dar. Bislang existiert keine nationale Best Practice Empfehlung für die Anwendung von Silber-Wundverbänden.Ziel dieser Arbeit war es daher, eine Sammlung von Best Practice Statements basierend auf einer strukturierten Befragung z...
Source: Wound Medicine - August 7, 2019 Category: General Medicine Source Type: research

Postoperative management of postpartum perineal tears
ConclusionsLocal therapy with Theresienol - an natural product based on natural fats and pure herbal extracts in the postoperative management of postpartum perineal tears significantly reduces the severity of clinical symptoms, and further monitoring and inclusion of new patients will show whether the risk of objective short-term and long-term complications is reduced. (Source: Wound Medicine)
Source: Wound Medicine - August 1, 2019 Category: General Medicine Source Type: research

A topical ointment formulation containing leaves extract of Aegialitis rotundifolia Roxb., accelerates excision, incision and burn wound healing in rats
ConclusionTherefore, the topical application of ARELE ointment formulations showed remarkable excision, incision and burn wound healing in Wistar rats thus showing its potential as a promising wound healing agent.Graphical abstract (Source: Wound Medicine)
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research

Wound healing effect of silver nanoparticles from Tridax procumbens leaf extracts on Pangasius hypophthalmus
In this study Silver nanoparticles were synthesized using Tridax procumbens leaf extract. Nanoparticles were characterized using UV–Vis absorption spectroscopy, and Scanning Electron Microscopy (SEM). The efficacy of the synthesized silver nanoparticles on wound healing was investigated in Pangasius hypohthalmus.Biosynthesis of silver nanoparticles from the leaf extract of Tridax procumbens was found to be cost effective and time conserving. We compared the effectiveness of the synthesized silver nanoparticles from Tridax procumbens on wound healing with silver nitrate and leaf extract.Collagen deposition and fibrosi...
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research

In vitro investigation of antibacterial activity against fecal bacteria infecting wounds
ConclusionThis in vitro assay is easy to use, partly simulates fecal bacterial growth in vivo, and can be used to measure fecal bacterial growth inhibition. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research

Elevated wound fluid pH correlates with increased risk of wound infection
ConclusionsThe strength of the relationship between wound pH and clinical judgement or enzyme activities observed in this study is not sufficient to promote the use of elevated pH alone as an indicator for wound infection. However, the use of pH in combination with other indicators for wound infection, such as elevated neutrophil enzyme activity, warrants further research. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research

Publisher's Note
Publication date: June 2019Source: Wound Medicine, Volume 25, Issue 1Author(s): (Source: Wound Medicine)
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research

Efficacy of selenium in controlling Acinetobacter baumannii associated wound infections
This study investigated the efficacy of the essential mineral, selenium (Se) in inhibiting skin-colonizing and biofilm forming abilities of A. baumannii in vitro.The effect of Se on A. baumannii adhesion and invasion of human skin keratinocytes (HEK001) was studied. Additionally, the efficacy of Se in inhibiting A. baumannii biofilm formation was determined using an in vitro collagen matrix wound model, and scanning electron microscopy (SEM) was done to visualize its potential antibiofilm effect. The effect of Se on critical A. baumannii genes for biofilm synthesis was also determined using real-time qPCR (RT-qPCR).Seleniu...
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research

Healing activity of Stryphnodendron adstringens (Mart.), a Brazilian tannin-rich species: A review of the literature and a case series
ConclusionConsidering the difficulty in treating chronic or extensive wounds, barbatimão could be an effective, low-cost phytotherapy formulation with low levels of toxicity. (Source: Wound Medicine)
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research

In vivo – Wound healing studies of Leptospermum scoparium honey loaded chitosan bioactive wound dressing
Publication date: September 2019Source: Wound Medicine, Volume 26, Issue 1Author(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the...
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research

Wound Healing Properties of Epiphyllum oxypetalum (DC.) Haw. Leaf Extract in Streptozotocin-induced Diabetic Mice by Topical Application
In conclusion, topical application of 96% ethanol extract of Epiphyllum oxypetalum leaves could accelerate the wound healing time in diabetic mice, where the best activity was shown by 20% Epiphyllum oxypetalum extract. (Source: Wound Medicine)
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

In vivo - Wound Healing Studies of Leptospermum scoparium Honey loaded Chitosan Bioactive Wound dressing
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the perfo...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

Biostimulation of venous chronic ulcers with platelet-rich plasma gel and biocompatible membranes of chitosan and alginate: a pilot study
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): Ana Luisa Muñoz, William Hernando Merchán, Ana Luiza Resende Pires, Ângela Maria Moraes, Lina Andrea GómezABSTRACTVenous ulcers are a common disease caused by circulatory insufficiency, having as characteristics slow healing and therefore a difficult treatment. Consequently, this disease has a high impact at personal, professional and social levels, representing large costs for both patients and healthcare system. The aim of the present pilot study was to evaluate the effectiveness of an alternative treatment for this ...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

Pilot-Study Switchable Film Dressing & NPWT: A non-interventional, non-placebo-controlled, national pilot study
Publication date: Available online 4 June 2019Source: Wound MedicineAuthor(s): Michael Schmitz (Source: Wound Medicine)
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

Topical mitomycin-C reduced number of myofibroblasts in healing anoplasty wounds in Wistar rats
Conclusions: Topical MMC reduced the myofibroblasts in the first week of healing anoplasty wounds in Wistar rats. (Source: Wound Medicine)
Source: Wound Medicine - May 11, 2019 Category: General Medicine Source Type: research

A Keratin-based biomaterial as a promising dresser for skin wound healing
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Saeid Vakilian, Fatemeh Jamshidi-adegani, Sulaiman Al-Shidhani, Muhammad U. Anwar, Rashid Al-Harrasi, Nasar Al-Wahaibi, Asim Qureshi, Sausan Alyaqoobi, Issa Al-Amri, Ahmed Al-Harrasi, Sulaiman Al-HashmiAbstractKeratin-based biomaterials can be considered as the beneficial platform for designing suitable wound dressers. One of the most common natural materials that are composed of keratin and lipid is snakes shed skin. In this new study, shed skin of two different Omani snakes; Bitis arietans snake (Puff adder, “P”) and Telescopus d...
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research

Topical mitomycin-c reduced myofibroblasts in healing anoplasty wounds in wistar rats
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Harsali Fransiscus Lampus, Suryani As’ad, Rahmawati Minhajat, Warsinggih, Mochammad Hatta, Rina Masadah, Akhmad Makhmudi, Rosdiana Natzir, Wardihan Sinrang, Fachruddin Benyamin, Agussalim Bukhari, Nathania Wonoputri, Nita Mariana, Tommy Rubiyanto Habar (Source: Wound Medicine)
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research

Evaluation of wound healing and anti-inflammatory activity of the leaves of calpurnia aurea (ait.) Benth (fabaceae) in mice
Publication date: Available online 29 March 2019Source: Wound MedicineAuthor(s): Getachew Ayal, Assefa Belay, Wubayehu KahaliwAbstractEthnopharmacological relevanceThe leaves of Calpurnia aurea (Ait.) Benth are used for wound healing activities through topical application in different communities in Ethiopia. The leaves had many confirmed in vitro activities that can promote wound healing effects. In spite of many claims and in vitro studies with supportive results in wound healing, no scientific study has been conducted on the wound healing and anti-inflammatory activity of leaves of Calpurnia aurea (Ait.) Benth on animal...
Source: Wound Medicine - March 31, 2019 Category: General Medicine Source Type: research

In vivo wound healing and antimicrobial activity of Alkanna strigose
Publication date: Available online 28 March 2019Source: Wound MedicineAuthor(s): Talal Aburjai, Reem Al-Janabi, Farah Al-Mamoori, Hanan AzzamAbstractSeveral plant preparations and extracts are used in folk medicine for treatment of topical wounds. Yet the validity of their use as well as the mechanism has not been ascertained in well-designed experimental settings. The wound healing activity of a topical hexane extract of Alkanna strigosa roots (HEASR) in excision and incision wound models in rats was evaluated. The pro-healing activity was assessed by the rate of wound contraction & wet granulation tissue weight and t...
Source: Wound Medicine - March 29, 2019 Category: General Medicine Source Type: research

The Effect of Short Duration of Electrical Stimulation on Wound Healing in Acute Wound in a Rat Model
ConclusionES application for 10-min significantly reduced inflammation, improved reepithelialization and angiogenesis when compared to shorter and longer applications. ES for 10 minutes also significantly improved wound healing when compared to the use of modern dressing alone. Therefore, it is recommended to apply ES for 10 minutes a day to improve wound healing. (Source: Wound Medicine)
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research

Long-term negative pressure wound therapy decreases a risk of diabetic foot amputation assessed in the university of Texas wound classification
Publication date: March 2019Source: Wound Medicine, Volume 24, Issue 1Author(s): Adam Węgrzynowski, Mikołaj Kamiński, Piotr Liszkowski, Jacek Soska, Aleksandra Araszkiewicz, Dorota Zozulińska-ZiółkiewiczAbstractBackgroundThe University of Texas Wound Classification is a tool assesing risk of amputation of patients with Diabetic Foot Ulceration (DFU). Negative Pressure Wound Therapy (NPWT) is a nonivasive system which was shown to be effective in healing chronic wounds. The aim of the study was to assess utility of long-term NPWT in healing diabetic foot wounds among Polish patients with diabetes.Material & ...
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research

Long-term Negative Pressure Wound Therapy Decreases Diabetic Foot's Risk of Amputation Assessed in the University of Texas Wound Classification
Publication date: Available online 15 February 2019Source: Wound MedicineAuthor(s): Adam Węgrzynowski, Mikołaj Kamiński, Piotr Liszkowski, Jacek Soska, Aleksandra Araszkiewicz, Dorota Zozulinska-ZiolkiewiczAbstractBackgroundThe University of Texas Wound Classification is a tool assesing risk of amputation of patients with Diabetic Foot Ulceration (DFU). Negative Pressure Wound Therapy (NPWT) is a nonivasive system which was shown to be effective in healing chronic wounds. The aim of the study was to assess utility of long-term NPWT in healing diabetic foot wounds among Polish patients with diabetes.Material & Method...
Source: Wound Medicine - February 16, 2019 Category: General Medicine Source Type: research

Wound healing characteristics of a novel wound healing ointment in an abrasive wound model: a randomised, intra-individual clinical investigation
ConclusionSuperficial cutaneous wounds treated with the novel wound healing ointment displayed a significant improvement of wound healing with an earlier onset of re-epithelization, faster wound closure and a better cosmetic outcome. Clinically relevant accelerated wound healing compared to traditional dry healing could be shown demonstrating the benefits of moist wound healing conditions also in the treatment of minor, superficial wounds (Clinical trial identification number: EUDAMED_CIV 17-04-019364). (Source: Wound Medicine)
Source: Wound Medicine - February 12, 2019 Category: General Medicine Source Type: research

Effectiveness of the sodium alginate as surgical sealant materials
Publication date: Available online 7 February 2019Source: Wound MedicineAuthor(s): Gulsan AS Kazi, Osamu YamamotoAbstractDeveloping biocompatible tissue adhesives is a highly desired goal of the tissue engineering due to adverse effects of the sutures. Sodium alginate is a natural linear polysaccharide and has biocompatibility, non-toxicity, non-immunogenicity, biodegradability, antimicrobial activity, and can be simply gelled with divalent cations and used in a number of biomedical applications. So, in this study, we use simple Na-alginate solution as surgical sealant for wound close. We prepared 0.3% (w/w) alginate hydro...
Source: Wound Medicine - February 8, 2019 Category: General Medicine Source Type: research

Wound healing models: A systematic review of animal and non-animal models
In conclusion, animal models despite their many disadvantages remain the best available alternative to study the complex cellular and molecular interactions that occur during the wound healing process in a biologically relevant environment. Multiple models are necessary to study different types of chronic wounds due to the lack of an ideal comprehensive model that is close to humans. (Source: Wound Medicine)
Source: Wound Medicine - January 1, 2019 Category: General Medicine Source Type: research

Wound Healing Models; A Systematic Review of Animal and Non-Animal Models
In conclusion, animal models despite their many disadvantages remain the best available alternative to study the complex cellular and molecular interactions that occur during the wound healing process in a biologically relevant environment. Multiple models are necessary to study different types of chronic wounds due to the lack of an ideal comprehensive model that is close to humans. (Source: Wound Medicine)
Source: Wound Medicine - December 30, 2018 Category: General Medicine Source Type: research

Wound Healing properties of Aqueous Extracts of Sargassum illicifolium: An In Vitro Assay
Publication date: Available online 24 November 2018Source: Wound MedicineAuthor(s): Amal D. Premarathna, T.H. Ranahewa, S.K. Wijesekera, R.R.M.K.K. Wijesundara, Anura P. Jayasooriya, Viskam Wijewardana, R.P.V.J. RajapakseAbstractBackgroundSeaweeds contain biologically active molecules which are important in the pharmaceutical industry. The present study was aimed to investigate the effects of aqueous extract of seaweeds:Sargassum illicifolium (S.i) on the stimulation of mouse fibroblast cell proliferation and migration.Materials and methodsSargassum illicifolium-SW12, Sargassum illicifolium-SW13, and Sargassum illicifolium...
Source: Wound Medicine - November 25, 2018 Category: General Medicine Source Type: research

Consensus recommendation: Indications and methods for microbiological wound diagnostics
ConclusionBeside a full understanding of all clinical symptoms and clinical experience of wound experts the correct microbiological wound investigation will be the basis for a succesfull management of infected wounds. (Source: Wound Medicine)
Source: Wound Medicine - November 6, 2018 Category: General Medicine Source Type: research

Consensus Recommendation Indications and methods for microbiological wound diagnostics
ConclusionBeside a full understanding of all clinical symptoms and clinical experience of wound experts the correct microbiological wound investigation will be the basis for a succesfull management of infected wounds. (Source: Wound Medicine)
Source: Wound Medicine - October 25, 2018 Category: General Medicine Source Type: research

Absorbable vs non absorbable sutures for wound closure. Systematic review of systematic reviews
Publication date: Available online 24 September 2018Source: Wound MedicineAuthor(s): Sharaf Sheik-Ali, Wilfried GuetsAbstractObjectiveTo provide an overview of evidence on Absorbable and non-absorbable sutures (AS & NAS) for the closure of surgical incisionsMethodsMedline, Embase and Cochrane library were searched for systematic reviews including randomised control trials (RCTs) on AS and NAS. Those that matched the inclusion criterion were analysed for data on surgical site infections, post operative complications and risk of wound dehiscence.ResultsThe systematic review of reviews yielded data on 5781 patients in 25 ...
Source: Wound Medicine - October 5, 2018 Category: General Medicine Source Type: research

Occurrence and persistence of biofilms on cared chronic wounds: A large multicentric clinical study
DiscussionThis large difference from the previous studies found in the literature which report 60% of biofilms on chronic wounds could be explained by the inclusion criteria and sampling procedures. (Source: Wound Medicine)
Source: Wound Medicine - October 5, 2018 Category: General Medicine Source Type: research

Wound dressings for leg ulcers in Germany: distribution, regional variations and health care providers
ConclusionIn Germany, a high level of use of hydroactive wound dressings in leg ulcers and marked regional variations were found. (Source: Wound Medicine)
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research

Disinfection of Pseudomonas aeruginosa-infected wounds in diabetic db/db mice by weakly acidic hypochlorous acid
ConclusionTwelve days of once-daily cleansing of P. aeruginosa-infected wounds on db/db diabetic mice with HOCl solution resulted in significantly decreased P. aeruginosa bioburden, albeit with a minor delay in wound repair. (Source: Wound Medicine)
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research

Regenerative effect of epiregulin-loaded hydrogel
Publication date: December 2018Source: Wound Medicine, Volume 23Author(s): Mario Migliario, Filippo RenòAbstractRapid and efficient wound healing response is essential to maintain whole organism integrity and homeostasis. Such process could be influenced by a plethora of factors that when interfering with the different healing phases finally result in impaired tissue repair. Furthermore, defective healing process is often associated with chronic and difficult to heal wounds, both conditions deeply affecting patients’ quality of life.Advanced wound management solutions are the new standard in difficult to heal ...
Source: Wound Medicine - September 21, 2018 Category: General Medicine Source Type: research

Low Dose Stingless Bee Honey Increases Viability of Human Dermal Fibroblasts That Could Potentially Promote Wound Healing
This study seeks to evaluate the effect of freeze-dried stingless bee honey on the cell viability and proliferative capacity of dermal fibroblast. Dermal fibroblast viability and proliferation will be evaluated via MTT assay, microscopic evaluation and cell cycle analysis. Short-term exposure of dermal fibroblasts to different honey doses revealed a multimodal pattern of increase in cell viability at the honey dose of 0.024, 200, and 6400 µg/ml. Treatment of the selected honey dose to dermal fibroblast proves to be non-toxic under microscopic evaluation and MTT assay. The selected dose of honey improves prolif...
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Regenerative effect of epiregulin–loaded hydrogel
Publication date: Available online 14 September 2018Source: Wound MedicineAuthor(s): Mario Migliario, Filippo RenòAbstractRapid and efficient wound healing response is essential to maintain whole organism integrity and homeostasis. Such process could be influenced by a plethora of factors that when interfering with the different healing phases finally result in impaired tissue repair. Furthermore, defective healing process is often associated with chronic and difficult to heal wounds, both conditions deeply affecting patients’ quality of life.Advanced wound management solutions are the new standard in difficul...
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Optimization of process conditions for chitosan-manuka honey film as wound contact layer for wound dressings
In this study, using solvent evaporation technique, chitosan-honey films were developed and the process parameters like concentration of chitosan, honey and glycerol were optimized using Response Surface Methodology (RSM) against the responses like Water Vapour Transmission Rate (WVTR), swelling ratio, antibacterial activity against Staphylococcus aureus and Escherichia coli, tensile strength and elongation. The effects of individual responses were discussed against all the variables using contour plots. The responses are optimized and the process parameters for achieving optimum responses to be used as a wound contact lay...
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Collagen aids in expediting the healing framework of diabetic ulcers
ConclusionCollagen with its Triple helical structure aids in the healing mechanism by imparting tensile strength to the wound by bridging various processes resulting in fibroplasias and epidermal resurfacing. This could possibly aid in expediting the sequential but overlapping phases by cementing fruitful interactions between cellular and extracellular matrix interfaces. (Source: Wound Medicine)
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Excision wound healing activity of a common biosurfactant produced by Pseudomonas sp.
Publication date: Available online 14 September 2018Source: Wound MedicineAuthor(s): Santanu Sana, Sriparna Datta, Dipa Biswas, Biswajit Auddy, Mradu Gupta, Helen ChattopadhyayAbstractBackgroundWound is an inherent process to regenerate the cellular cohesion of tissue. Present study deal with the accelerating potentiality of rhamnolipid produced by P. aeruginosa C2 using fat of Catla catla fish as an economic substrate to heal wound in a shorter time.MethodologyAn ointment containing rhamnolipid (5 g/l) was administered on the back of each wister rat after creating excision wound of 50 mm2. The examined parameters w...
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Disinfection of pseudomonas aeruginosa-infected wounds in diabetic db/db m679d
ConclusionTwelve days of once-daily cleansing of P. aeruginosa-infected wounds on db/db diabetic mice with HOCl solution resulted in significantly decreased P. aeruginosa bioburden, albeit with a minor delay in wound repair. (Source: Wound Medicine)
Source: Wound Medicine - September 15, 2018 Category: General Medicine Source Type: research

Engineered protein hydrogel for open wound management in Canines
In conclusion, PAMG based adhesive hydrogel offers faster wound healing of open wounds of Canines. (Source: Wound Medicine)
Source: Wound Medicine - July 21, 2018 Category: General Medicine Source Type: research

Global Incidence and Prevalence of Pressure Injuries in Public Hospitals: A Systematic Review
ConclusionsA careful and systematic review of all the retrieved citations yielded a rich source of evidence. In this systematic review of the literature, most of the studies employed the skin assessment technique to collate their data. (Source: Wound Medicine)
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Development of antimicrobial colloidal silver incorporated lyophilized biopolymer wafers for wound care
ConclusionLyophilized antimicrobial wafers were developed as a successful wound dressing for combating microbial infections at the site of application with enhanced wound healing activity.Graphical abstract (Source: Wound Medicine)
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Allogeneic fibroblast cell therapy in the treatment of recessive dystrophic epidermolysis bullosa
ConclusionsIntradermal administration of allogeneic fibroblasts is a safe and effective method of treatment of non-healing wounds in recessive dystrophic epidermolysis bullosa. (Source: Wound Medicine)
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Effects of platelet-rich plasma and carbonated hydroxyapatite combination on cranial defect Bone Regeneration: An animal study
ConclusionA combination of PRP and CHA as a bone regeneration scaffold showed a histologically increased bone formation. (Source: Wound Medicine)
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Evaluation of in vivo wound healing and anti-inflammatory activity of crude extract of the fruits of Brucea antidysentrica in mice
Publication date: June 2018Source: Wound Medicine, Volume 21Author(s): Zenaw Tessema, Eyasu Makonnen, Asfaw Debella, Yalew MollaAbstractBackgroundBrucea antidysentrica is traditionally used to treat various conditions. Though, fruits of B. antidysentrica are claimed to promote wound healing; there is no scientific evidence that supports the traditional claim. Therefore, this study was aimed to evaluate the wound healing and anti-inflammatory activities of the extract.MethodsExtracts were formulated as 1% and 2% ointments. Simple and nitrofurazone (0.2%) ointments were used as controls for the wound healing. A dose of 100, ...
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Effects of hypericum perforatum, clinoptilolite and hydrocolloid dressing on wound healing in diabetic rats
Publication date: September 2018Source: Wound Medicine, Volume 22Author(s): Serap Gokce, Aynur Tureyen, Alpaslan Gokcimen (Source: Wound Medicine)
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Matrix metalloproteinase 9 (MMP9) in wound healing of diabetic foot ulcer: Molecular target and structure-based drug design
Publication date: September 2018Source: Wound Medicine, Volume 22Author(s): Maywan Hariono, Sri H. Yuliani, Enade P. Istyastono, Florentinus D.O. Riswanto, Christophorus F. AdhipanditoAbstractMatrix Metalloproteinase 9 (MMP9) is one of the many zinc-dependent endopeptidases found in the body, which is also involved in delaying wound healing by degrading extracellular matrices associated with normal tissue remodelling processes. In Diabetic Foot Ulcer (DFU), this protein is highly expressed especially at the stage where wound healing is poor. Currently, MMP9 is becoming one of the interesting targets in the discovery and de...
Source: Wound Medicine - July 10, 2018 Category: General Medicine Source Type: research

Global Incidence and Prevalence of Pressure Injuries in Public Hospitals: A Systematic Review
ConclusionsA careful and systematic review of all the retrieved citations yielded a rich source of evidence. In this systematic review of the literature, most of the studies employed the skin assessment technique to collate their data. (Source: Wound Medicine)
Source: Wound Medicine - July 5, 2018 Category: General Medicine Source Type: research