Pilot-study switchable film dressing & elderly skin/patients with chronic wounds: A non-interventional, non-placebo-controlled, national pilot study
Publication date: September 2020Source: Wound Medicine, Volume 30Author(s): Michael Schmitz, Nesat Mustafi, Sven Rogmans, Sabine Kasparek (Source: Wound Medicine)
Source: Wound Medicine - July 13, 2020 Category: General Medicine Source Type: research

Graphene-based materials in drug delivery and growth factor release: A critical review
Publication date: Available online 6 July 2020Source: Wound MedicineAuthor(s): Amirhossein Ghaemi, Shohreh Javadi, Maryam Kavousi Heidari, Hamid Rashedi, Fatemeh Yazdian, Meisam Omidi, Zahra Tavakoli, Mojgan Sheikhpour (Source: Wound Medicine)
Source: Wound Medicine - July 7, 2020 Category: General Medicine Source Type: research

Gross and histopathological effects of dimethyl sulfoxide on wound healing in rats
Publication date: Available online 30 June 2020Source: Wound MedicineAuthor(s): Vinay Kant, Babu Lal Jangir, Vinod Kumar (Source: Wound Medicine)
Source: Wound Medicine - July 1, 2020 Category: General Medicine Source Type: research

Healing potential of Caiman yacare (Daudin, 1802) visceral fat oil
Publication date: Available online 30 June 2020Source: Wound MedicineAuthor(s): Lucas Polizzeli Azevedo, Rosa Helena dos Santos Ferraz, Márcia Regina Lopes de Magalhães, Ana Paula Oliveira, Bruno Cogliati, Larissa Maria Scalon Lemos, Paola Cristina Branco, Demétrio de Abreu Sousa, José Roberto Machado Cunha da Silva, Leandro Nogueira Pressinotti (Source: Wound Medicine)
Source: Wound Medicine - June 30, 2020 Category: General Medicine Source Type: research

Healing potential of chitosan and decellularized intestinal matrix with mesenchymal stem cells and growth factor in burn wound in rat
Publication date: Available online 20 June 2020Source: Wound MedicineAuthor(s): Sangeetha Palakkara, Swapan Kumar Maiti, Divya Mohan, Shivaraju S., Raguvaran R., Kalaiselvan E, Naveen Kumar (Source: Wound Medicine)
Source: Wound Medicine - June 22, 2020 Category: General Medicine Source Type: research

Pilot-Study Switchable Film Dressing & Elderly skin / patients with chronic wounds: A non-interventional, non-placebo-controlled, national pilot study
Publication date: Available online 13 June 2020Source: Wound MedicineAuthor(s): Michael Schmitz, Nesat Mustafi, Sven Rogmans, Sabine Kasparek (Source: Wound Medicine)
Source: Wound Medicine - June 14, 2020 Category: General Medicine Source Type: research

Platelet-Rich Fibrin (PRF) Membranes Accelerate Open Wound Healing Better Than Amniotic Membranes: A Histological Study on the Proliferation Phase
Publication date: Available online 8 June 2020Source: Wound MedicineAuthor(s): Rezmelia Sari, Grace Sekar Larasati, Nurul Ghoutsiyah Kuncorowati, Ahmad Syaify (Source: Wound Medicine)
Source: Wound Medicine - June 9, 2020 Category: General Medicine Source Type: research

Austrian natural ointment (Theresienöl®) with a high potential in wound healing – a European Review
Publication date: Available online 8 June 2020Source: Wound MedicineAuthor(s): Strahil Strashilov, Stanislav Slavchev, Ahmed Aljowder, Polina Vasileva, Sirona Postelnicu-Gherasim, Stoyan Kostov, Angel Yordanov (Source: Wound Medicine)
Source: Wound Medicine - June 9, 2020 Category: General Medicine Source Type: research

Honey based treatment strategies for infected wounds and burns: A systematic review of recent pre-clinical research
Publication date: Available online 29 May 2020Source: Wound MedicineAuthor(s): Gopal Shankar Krishnakumar, Balaji Mahendiran, Subiksha Gopalakrishnan, Shalini Muthusamy, Sinduja Malarkodi Elangovan (Source: Wound Medicine)
Source: Wound Medicine - May 30, 2020 Category: General Medicine Source Type: research

Predictors for success of hyperbaric oxygen therapy for problematic wounds
Publication date: Available online 12 May 2020Source: Wound MedicineAuthor(s): Kamonwan Jenwitheesuk, Ajanee Mahakkanukrauh, Wiyada Punjaruk, Kriangsak Jenwitheesuk, Kengkart Winaikosol, Puttama Punyavong, Narongchai Wongkonkitsin, Supatcha Prasertcharoensuk, Phasuk Limrattanapimpa (Source: Wound Medicine)
Source: Wound Medicine - May 13, 2020 Category: General Medicine Source Type: research

Perineal wound outcomes after extralevator abdominoperineal excision for rectal adenocarcinoma—A tertiary care centre experience
Publication date: June 2020Source: Wound Medicine, Volume 29Author(s): Royson Dsouza, Gigi Varghese, Rohin Mittal, Mark Ranjan Jesudason (Source: Wound Medicine)
Source: Wound Medicine - April 27, 2020 Category: General Medicine Source Type: research

Perineal Wound Outcomes after Extralevator Abdominoperineal Excision for Rectal Adenocarcinoma- A Tertiary Care Centre Experience: Type of article: Original full length article
Publication date: Available online 20 April 2020Source: Wound MedicineAuthor(s): Royson Dsouza, Gigi Varghese, Rohin Mittal, Mark RanjanJesudason (Source: Wound Medicine)
Source: Wound Medicine - April 21, 2020 Category: General Medicine Source Type: research

Effect of fermented and green Aspalathus linearis extract loaded hydrogel on surgical wound healing in Sprague Dawley rats
Publication date: Available online 4 April 2020Source: Wound MedicineAuthor(s): Rukayat D Elegbede, Margaret O Ilomuanya, Abimbola A Sowemimo, Amarachi Nneji, Elizabeth Joubert, Dalene de Beer, Trevor Koekemoer, Maryna van de Venter (Source: Wound Medicine)
Source: Wound Medicine - April 5, 2020 Category: General Medicine Source Type: research

Extracts of Tridax procumbens linn leaves causes wound healing in diabetic and Non-diabetic laboratory animals
Publication date: Available online 21 March 2020Source: Wound MedicineAuthor(s): Alankar Shrivastav, Arun Kumar Mishra, M. Abid, Aftab Ahmad, Mohammed Fabuzinadah, Najam Ali Khan (Source: Wound Medicine)
Source: Wound Medicine - March 21, 2020 Category: General Medicine Source Type: research

Evaluation of bacteriophage products against burn wound methicillin-resistant Staphylococcus aureus (MRSA) infections
ConclusionsIn conclusion the recombinant Nano phage gel is efficacy to treat and prevent MRSA burn wound infection. (Source: Wound Medicine)
Source: Wound Medicine - January 27, 2020 Category: General Medicine Source Type: research

The efficacy of platelet gel derived from umbilical cord blood on diabetic foot ulcers: A double-blind randomized clinical trial
ConclusionThe present study provides evidence that there are no significant differences in the size of wound among PG, PPP, and placebo groups. (Source: Wound Medicine)
Source: Wound Medicine - January 22, 2020 Category: General Medicine Source Type: research

Healing of Pseudomonas aeruginosa-infected wounds in diabetic db/db mice by weakly acidic hypochlorous acid cleansing and silver nanoparticle/chitin-nanofiber sheet covering
This study aimed to evaluate disinfection and wound healing by a combination of cleansing with HClO and covering with CNFS/Ag NPs daily for 3 days. Applying HClO + CNFS/Ag NPs daily for 3 days and then cleansing with just pure water and covering with CNFS alone daily for 9 days were performed for Pseudomonas aeruginosa-infected wounds in db/db diabetic mice. We found a significant enhancement of wound healing and a reduction of bacteria counts compared to the controls. Histological examination showed significantly advanced granulation tissue and capillary formations in the wounds on Day 12. These results suggest that limit...
Source: Wound Medicine - January 19, 2020 Category: General Medicine Source Type: research

The applied anatomy of human skin: a model for regeneration
Publication date: Available online 18 January 2020Source: Wound MedicineAuthor(s): Joseph M. Abdo, Nikolai A. Sopko, Stephen M. MilnerABSTRACTAutologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions of macromolecules, or growth factors have contributed to the resurfacing of burns and large wounds. There are, however, significant limitations with these therapies. No tissue-engineered substitute can fully replace the split-thickness skin graft for permanent coverage of full-thickness skin loss in one step, and none contain a functional vascular plexus. Current research characterizes ski...
Source: Wound Medicine - January 19, 2020 Category: General Medicine Source Type: research

Fabrication of Pomegranate/Honey Nanofibers for Use as Antibacterial Wound Dressings
Publication date: Available online 18 January 2020Source: Wound MedicineAuthor(s): Sara S. Abou Zekry, Ahmed Abdellatif, Hassan M.E. AzzazyAbstractHoney, pomegranate peel extract and bee venom, were used in combination with polyvinyl alcohol to develop a novel nanofibrous wound dressing. Methanolic pomegranate peel extract was prepared and mixed with either Manuka honey or lyophilized multiflora honey powder together with bee venom. The formulas were tested for their antibacterial activity, cytotoxicity, and wound healing activity in an excisional wound rat model. Scanning electron microscopy showed that lyophilized honey ...
Source: Wound Medicine - January 18, 2020 Category: General Medicine Source Type: research

The efficacy of platelet gel derived from umbilical cord blood on diabetic foot ulcers: a double -blind randomized clinical trial
ConclusionThe present study provides evidence that there are no significant differences in the size of wound among PG, PPP, and placebo group. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research

Overview of 10 years of practice with CACIPLIQ20® matrix therapy as a healing agent for hard to heal wounds: efficacy, cost-effectiveness and future perspectives
ConclusionsCACIPLIQ20® can heal chronic wounds of various etiologies, sizes and ages in approximately two months, while being cost-effective. By doing so, this treatment can provide major improvement of quality of life through rapid and complete healing of chronic, hard-to-heal wounds and can reduce the economic burden of chronic wounds for health care agencies. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research

Development of in situ gels of nano calcium oxide for healing of burns
ConclusionIn situ gels of NCO were developed as a formulation for effective treatment of burns and to aid in skin regeneration. (Source: Wound Medicine)
Source: Wound Medicine - January 9, 2020 Category: General Medicine Source Type: research

Evaluation of In Vivo Wound Healing Activity of Plumeria obtusa L. (Champa) Spray in Rats
Publication date: Available online 12 November 2019Source: Wound MedicineAuthor(s): Tanay Bihani, Abhishek Bura, Nilesh MhaskeAbstractWound healing is a general repair response or process of the body immediately after the disruption of the skin integrity. However wound healing is a complex process in which body repairs itself. The aim of this research is to study the wound healing activity of ethanolic extract of Plumeria obtusa leaves and to study the efficacy of formulated 2.5%, 5% and 10% Plumeria obtusa sprays in in-vivo wound healing models. The spray was prepared in three formulations F1, F2 and F3 containing 2.5% (5...
Source: Wound Medicine - November 12, 2019 Category: General Medicine Source Type: research

Change over time of the ankle brachial index
Conclusionthese data demonstrate a change in ABI that is minimal and thus suggest that without intervening medical treatments that would change the ABI, routinely repeating this test is not warranted. (Source: Wound Medicine)
Source: Wound Medicine - October 23, 2019 Category: General Medicine Source Type: research

Topical application of lyophilized and powdered human amniotic membrane promotes diabetic ulcer healing
ConclusionsAMX ameliorated pain and extent of a chronic diabetic ulcer. The effect could be ascribed to angiogenesis and epithelium stimulation that was confirmed in in vitro. Multiple wound healing-involved proteins were detected but further studies are needed to assess their specific role. (Source: Wound Medicine)
Source: Wound Medicine - August 11, 2019 Category: General Medicine Source Type: research

Best practice recommendations for silver wound dressings: Results of an expert survey aiming to reach a consensus
Publication date: Available online 5 August 2019Source: Wound MedicineAuthor(s): J G Böttrich, H Braunwarth, J Dissemond, K C Münter, F Schümmelfeder, P WilkenZusammenfassungAkute und chronische Wunden mit lokalen Infektionszeichen oder einer kritischen Kolonisation stellen in der Versorgung eine interdisziplinäre und interprofessionelle Herausforderung in der Medizin dar. Bislang existiert keine nationale Best Practice Empfehlung für die Anwendung von Silber-Wundverbänden.Ziel dieser Arbeit war es daher, eine Sammlung von Best Practice Statements basierend auf einer strukturierten Befragung z...
Source: Wound Medicine - August 6, 2019 Category: General Medicine Source Type: research

Postoperative management of postpartum perineal tears
ConclusionsLocal therapy with Theresienol - an natural product based on natural fats and pure herbal extracts in the postoperative management of postpartum perineal tears significantly reduces the severity of clinical symptoms, and further monitoring and inclusion of new patients will show whether the risk of objective short-term and long-term complications is reduced. (Source: Wound Medicine)
Source: Wound Medicine - August 1, 2019 Category: General Medicine Source Type: research

A topical ointment formulation containing leaves extract of Aegialitis rotundifolia Roxb., accelerates excision, incision and burn wound healing in rats
ConclusionTherefore, the topical application of ARELE ointment formulations showed remarkable excision, incision and burn wound healing in Wistar rats thus showing its potential as a promising wound healing agent.Graphical abstract (Source: Wound Medicine)
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research

Wound healing effect of silver nanoparticles from Tridax procumbens leaf extracts on Pangasius hypophthalmus
In this study Silver nanoparticles were synthesized using Tridax procumbens leaf extract. Nanoparticles were characterized using UV–Vis absorption spectroscopy, and Scanning Electron Microscopy (SEM). The efficacy of the synthesized silver nanoparticles on wound healing was investigated in Pangasius hypohthalmus.Biosynthesis of silver nanoparticles from the leaf extract of Tridax procumbens was found to be cost effective and time conserving. We compared the effectiveness of the synthesized silver nanoparticles from Tridax procumbens on wound healing with silver nitrate and leaf extract.Collagen deposition and fibrosi...
Source: Wound Medicine - July 28, 2019 Category: General Medicine Source Type: research

In vitro investigation of antibacterial activity against fecal bacteria infecting wounds
ConclusionThis in vitro assay is easy to use, partly simulates fecal bacterial growth in vivo, and can be used to measure fecal bacterial growth inhibition. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research

Elevated wound fluid pH correlates with increased risk of wound infection
ConclusionsThe strength of the relationship between wound pH and clinical judgement or enzyme activities observed in this study is not sufficient to promote the use of elevated pH alone as an indicator for wound infection. However, the use of pH in combination with other indicators for wound infection, such as elevated neutrophil enzyme activity, warrants further research. (Source: Wound Medicine)
Source: Wound Medicine - July 25, 2019 Category: General Medicine Source Type: research

Publisher's Note
Publication date: June 2019Source: Wound Medicine, Volume 25, Issue 1Author(s): (Source: Wound Medicine)
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research

Efficacy of selenium in controlling Acinetobacter baumannii associated wound infections
This study investigated the efficacy of the essential mineral, selenium (Se) in inhibiting skin-colonizing and biofilm forming abilities of A. baumannii in vitro.The effect of Se on A. baumannii adhesion and invasion of human skin keratinocytes (HEK001) was studied. Additionally, the efficacy of Se in inhibiting A. baumannii biofilm formation was determined using an in vitro collagen matrix wound model, and scanning electron microscopy (SEM) was done to visualize its potential antibiofilm effect. The effect of Se on critical A. baumannii genes for biofilm synthesis was also determined using real-time qPCR (RT-qPCR).Seleniu...
Source: Wound Medicine - June 13, 2019 Category: General Medicine Source Type: research

Healing activity of Stryphnodendron adstringens (Mart.), a Brazilian tannin-rich species: A review of the literature and a case series
ConclusionConsidering the difficulty in treating chronic or extensive wounds, barbatimão could be an effective, low-cost phytotherapy formulation with low levels of toxicity. (Source: Wound Medicine)
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research

In vivo – Wound healing studies of Leptospermum scoparium honey loaded chitosan bioactive wound dressing
Publication date: September 2019Source: Wound Medicine, Volume 26, Issue 1Author(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the...
Source: Wound Medicine - June 8, 2019 Category: General Medicine Source Type: research

Wound Healing Properties of Epiphyllum oxypetalum (DC.) Haw. Leaf Extract in Streptozotocin-induced Diabetic Mice by Topical Application
In conclusion, topical application of 96% ethanol extract of Epiphyllum oxypetalum leaves could accelerate the wound healing time in diabetic mice, where the best activity was shown by 20% Epiphyllum oxypetalum extract. (Source: Wound Medicine)
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

In vivo - Wound Healing Studies of Leptospermum scoparium Honey loaded Chitosan Bioactive Wound dressing
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): R. Rathinamoorthy, L. SasikalaAbstractThe research aimed to develop a bioactive wound dressing using chitosan and Leptospermum scoparium honey, which is commonly known as Manuka Honey. The wound dressing was developed using solvent- casting technique with the honey as a drug. The wound healing ability of the developed dressing was evaluated against three different wound models namely excision, incision and burn wound model in terms of wound contraction percentage and histopathological examination. The results of the study revealed that the perfo...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

Biostimulation of venous chronic ulcers with platelet-rich plasma gel and biocompatible membranes of chitosan and alginate: a pilot study
Publication date: Available online 5 June 2019Source: Wound MedicineAuthor(s): Ana Luisa Muñoz, William Hernando Merchán, Ana Luiza Resende Pires, Ângela Maria Moraes, Lina Andrea GómezABSTRACTVenous ulcers are a common disease caused by circulatory insufficiency, having as characteristics slow healing and therefore a difficult treatment. Consequently, this disease has a high impact at personal, professional and social levels, representing large costs for both patients and healthcare system. The aim of the present pilot study was to evaluate the effectiveness of an alternative treatment for this ...
Source: Wound Medicine - June 6, 2019 Category: General Medicine Source Type: research

Pilot-Study Switchable Film Dressing & NPWT: A non-interventional, non-placebo-controlled, national pilot study
Publication date: Available online 4 June 2019Source: Wound MedicineAuthor(s): Michael Schmitz (Source: Wound Medicine)
Source: Wound Medicine - June 5, 2019 Category: General Medicine Source Type: research

Topical mitomycin-C reduced number of myofibroblasts in healing anoplasty wounds in Wistar rats
Conclusions: Topical MMC reduced the myofibroblasts in the first week of healing anoplasty wounds in Wistar rats. (Source: Wound Medicine)
Source: Wound Medicine - May 11, 2019 Category: General Medicine Source Type: research

A Keratin-based biomaterial as a promising dresser for skin wound healing
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Saeid Vakilian, Fatemeh Jamshidi-adegani, Sulaiman Al-Shidhani, Muhammad U. Anwar, Rashid Al-Harrasi, Nasar Al-Wahaibi, Asim Qureshi, Sausan Alyaqoobi, Issa Al-Amri, Ahmed Al-Harrasi, Sulaiman Al-HashmiAbstractKeratin-based biomaterials can be considered as the beneficial platform for designing suitable wound dressers. One of the most common natural materials that are composed of keratin and lipid is snakes shed skin. In this new study, shed skin of two different Omani snakes; Bitis arietans snake (Puff adder, “P”) and Telescopus d...
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research

Topical mitomycin-c reduced myofibroblasts in healing anoplasty wounds in wistar rats
Publication date: Available online 26 April 2019Source: Wound MedicineAuthor(s): Harsali Fransiscus Lampus, Suryani As’ad, Rahmawati Minhajat, Warsinggih, Mochammad Hatta, Rina Masadah, Akhmad Makhmudi, Rosdiana Natzir, Wardihan Sinrang, Fachruddin Benyamin, Agussalim Bukhari, Nathania Wonoputri, Nita Mariana, Tommy Rubiyanto Habar (Source: Wound Medicine)
Source: Wound Medicine - April 27, 2019 Category: General Medicine Source Type: research

Evaluation of wound healing and anti-inflammatory activity of the leaves of calpurnia aurea (ait.) Benth (fabaceae) in mice
Publication date: Available online 29 March 2019Source: Wound MedicineAuthor(s): Getachew Ayal, Assefa Belay, Wubayehu KahaliwAbstractEthnopharmacological relevanceThe leaves of Calpurnia aurea (Ait.) Benth are used for wound healing activities through topical application in different communities in Ethiopia. The leaves had many confirmed in vitro activities that can promote wound healing effects. In spite of many claims and in vitro studies with supportive results in wound healing, no scientific study has been conducted on the wound healing and anti-inflammatory activity of leaves of Calpurnia aurea (Ait.) Benth on animal...
Source: Wound Medicine - March 31, 2019 Category: General Medicine Source Type: research

In vivo wound healing and antimicrobial activity of Alkanna strigose
Publication date: Available online 28 March 2019Source: Wound MedicineAuthor(s): Talal Aburjai, Reem Al-Janabi, Farah Al-Mamoori, Hanan AzzamAbstractSeveral plant preparations and extracts are used in folk medicine for treatment of topical wounds. Yet the validity of their use as well as the mechanism has not been ascertained in well-designed experimental settings. The wound healing activity of a topical hexane extract of Alkanna strigosa roots (HEASR) in excision and incision wound models in rats was evaluated. The pro-healing activity was assessed by the rate of wound contraction & wet granulation tissue weight and t...
Source: Wound Medicine - March 29, 2019 Category: General Medicine Source Type: research

The Effect of Short Duration of Electrical Stimulation on Wound Healing in Acute Wound in a Rat Model
ConclusionES application for 10-min significantly reduced inflammation, improved reepithelialization and angiogenesis when compared to shorter and longer applications. ES for 10 minutes also significantly improved wound healing when compared to the use of modern dressing alone. Therefore, it is recommended to apply ES for 10 minutes a day to improve wound healing. (Source: Wound Medicine)
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research

Long-term negative pressure wound therapy decreases a risk of diabetic foot amputation assessed in the university of Texas wound classification
Publication date: March 2019Source: Wound Medicine, Volume 24, Issue 1Author(s): Adam Węgrzynowski, Mikołaj Kamiński, Piotr Liszkowski, Jacek Soska, Aleksandra Araszkiewicz, Dorota Zozulińska-ZiółkiewiczAbstractBackgroundThe University of Texas Wound Classification is a tool assesing risk of amputation of patients with Diabetic Foot Ulceration (DFU). Negative Pressure Wound Therapy (NPWT) is a nonivasive system which was shown to be effective in healing chronic wounds. The aim of the study was to assess utility of long-term NPWT in healing diabetic foot wounds among Polish patients with diabetes.Material & ...
Source: Wound Medicine - February 23, 2019 Category: General Medicine Source Type: research

Long-term Negative Pressure Wound Therapy Decreases Diabetic Foot's Risk of Amputation Assessed in the University of Texas Wound Classification
Publication date: Available online 15 February 2019Source: Wound MedicineAuthor(s): Adam Węgrzynowski, Mikołaj Kamiński, Piotr Liszkowski, Jacek Soska, Aleksandra Araszkiewicz, Dorota Zozulinska-ZiolkiewiczAbstractBackgroundThe University of Texas Wound Classification is a tool assesing risk of amputation of patients with Diabetic Foot Ulceration (DFU). Negative Pressure Wound Therapy (NPWT) is a nonivasive system which was shown to be effective in healing chronic wounds. The aim of the study was to assess utility of long-term NPWT in healing diabetic foot wounds among Polish patients with diabetes.Material & Method...
Source: Wound Medicine - February 16, 2019 Category: General Medicine Source Type: research

Wound healing characteristics of a novel wound healing ointment in an abrasive wound model: a randomised, intra-individual clinical investigation
ConclusionSuperficial cutaneous wounds treated with the novel wound healing ointment displayed a significant improvement of wound healing with an earlier onset of re-epithelization, faster wound closure and a better cosmetic outcome. Clinically relevant accelerated wound healing compared to traditional dry healing could be shown demonstrating the benefits of moist wound healing conditions also in the treatment of minor, superficial wounds (Clinical trial identification number: EUDAMED_CIV 17-04-019364). (Source: Wound Medicine)
Source: Wound Medicine - February 12, 2019 Category: General Medicine Source Type: research

Effectiveness of the sodium alginate as surgical sealant materials
Publication date: Available online 7 February 2019Source: Wound MedicineAuthor(s): Gulsan AS Kazi, Osamu YamamotoAbstractDeveloping biocompatible tissue adhesives is a highly desired goal of the tissue engineering due to adverse effects of the sutures. Sodium alginate is a natural linear polysaccharide and has biocompatibility, non-toxicity, non-immunogenicity, biodegradability, antimicrobial activity, and can be simply gelled with divalent cations and used in a number of biomedical applications. So, in this study, we use simple Na-alginate solution as surgical sealant for wound close. We prepared 0.3% (w/w) alginate hydro...
Source: Wound Medicine - February 8, 2019 Category: General Medicine Source Type: research

Wound healing models: A systematic review of animal and non-animal models
In conclusion, animal models despite their many disadvantages remain the best available alternative to study the complex cellular and molecular interactions that occur during the wound healing process in a biologically relevant environment. Multiple models are necessary to study different types of chronic wounds due to the lack of an ideal comprehensive model that is close to humans. (Source: Wound Medicine)
Source: Wound Medicine - January 1, 2019 Category: General Medicine Source Type: research