The Effect of Foal or Adult Horse Plasma on Equine Monocyte-Derived Dendritic Cell Phenotype and Function
Publication date: Available online 23 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Brina S. Lopez, David J. Hurley, Shyla Giancola, Steeve Giguère, Kelsey A. Hart (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 24, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: August 2020Source: Veterinary Immunology and Immunopathology, Volume 226Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 15, 2020 Category: Veterinary Research Source Type: research

Development and characterization of novel mouse monoclonal antibodies against chicken chemokine CC motif ligand 4
Publication date: Available online 10 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Mingmin Lu, Woo H. Kim, Hyun S. Lillehoj, Charles Li (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 12, 2020 Category: Veterinary Research Source Type: research

Immunohistochemical Identification of T and B Lymphocytes in Formalin-Fixed Paraffin-Embedded Chicken Tissues Using Commercial Antibodies
Publication date: Available online 9 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Aoi Kurokawa, Yu Yamamoto (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 10, 2020 Category: Veterinary Research Source Type: research

Development and evaluation of a real-time PCR panel for the detection of 20 immune markers in Cattle and Sheep
Publication date: Available online 9 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Elena L. Sassu, Richard T. Kangethe, Tirumala Bharani K. Settypalli, Tesfaye Rufael Chibssa, Giovanni Cattoli, Viskam Wijewardana (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 10, 2020 Category: Veterinary Research Source Type: research

Intra-articular xenogeneic mesenchymal stem cell-based therapy increases CD4+CD25+ cells in synovial fluid
Publication date: Available online 8 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Kristen Lamers, Monica Baquero, Niel Karrow, Mark Hurtig (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 9, 2020 Category: Veterinary Research Source Type: research

Anatomical distribution of respiratory tract leukocyte cell subsets in neonatal calves
Publication date: Available online 2 July 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Quinn K. Kolar, Lindsey A. Waddell, Anna Raper, Mara S. Rocchi, Darren J. Shaw, Alexander Corbishley, Jayne C. Hope (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - July 3, 2020 Category: Veterinary Research Source Type: research

Supplemental dietary selenium enhances immune responses conferred by a vaccine against low pathogenicity avian influenza virus
Publication date: Available online 25 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Bahram Shojadoost, Khaled Taha-Abdelaziz, Tamiru Negash Alkie, Alexander Bekele-Yitbarek, Neda Barjesteh, Adrianna Laursen, Trevor K. Smith, Janan Shojadoost, Shayan Sharif (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 27, 2020 Category: Veterinary Research Source Type: research

Immune Responses and Clinical Effects of Experimental challenge of Elk with Brucella abortus strain 2308
Publication date: Available online 21 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): S.C. Olsen, P. Boggiatto, C. Kanipe (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 23, 2020 Category: Veterinary Research Source Type: research

Serum neutralising antibody titres against a lineage 2 neuroinvasive West Nile Virus strain in response to vaccination with an inactivated lineage 1 vaccine in a European endemic area
Publication date: Available online 20 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Orsolya Fehér, Tamás Bakonyi, Mónika Barna, Anna Nagy, Mária Takács, Ottó Szenci, Kinga Joó, Sára Sárdi, Orsolya Korbacska-Kutasi (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 21, 2020 Category: Veterinary Research Source Type: research

Chemokine gene expression influences metastasis and survival time of female dogs with mammary carcinoma
Publication date: Available online 13 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Harsha Ariyarathna, Neroli Thomson, Danielle Aberdein, John S Munday (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 15, 2020 Category: Veterinary Research Source Type: research

Impact of birth weight and neonatal nutritional interventions with micronutrients and bovine colostrum on the development of piglet immune response during the peri-weaning period
Publication date: August 2020Source: Veterinary Immunology and Immunopathology, Volume 226Author(s): Luca Lo Verso, J. Jacques Matte, Jérôme Lapointe, Guylaine Talbot, Nathalie Bissonnette, Mylène Blais, Frédéric Guay, Martin Lessard (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 13, 2020 Category: Veterinary Research Source Type: research

Safety and Immunomodulatory Properties of Equine Peripheral Blood-derived Mesenchymal Stem Cells in Healthy Cats
Publication date: Available online 11 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Yves Debosschere, Eva Depuydt, Glenn Pauwelyn, Charlotte Beerts, Lore Van Hecke, Leen Verhaert, Luc Duchateau, Jimmy Saunders, Liesa Tack, Jan H. Spaas (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 13, 2020 Category: Veterinary Research Source Type: research

Comparison of serum cytokine concentrations between healthy dogs and canine osteosarcoma patients at the time of diagnosis
Publication date: Available online 10 June 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Carolina Allende, Berta Higgins, Jennifer Johns (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 10, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: July 2020Source: Veterinary Immunology and Immunopathology, Volume 225Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 10, 2020 Category: Veterinary Research Source Type: research

Mycoplasma bovis induces matrix metalloproteinase-3 expression in bovine synovial cells via up-regulation of interleukin-1β expression in mononuclear cells
Publication date: Available online 31 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Koji Nishi, Satoshi Gondaira, Mariko Okamoto, Reina Watanabe, Yuki Hirano, Jumpei Fujiki, Hidetomo Iwano, Hidetoshi Higuchi (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - June 1, 2020 Category: Veterinary Research Source Type: research

Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tract
Publication date: Available online 27 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Zofia M. Lisowski, Kristin A. Sauter, Lindsey A. Waddell, David A. Hume, Scott Pirie, Neil P.H. Hudson (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 29, 2020 Category: Veterinary Research Source Type: research

Type I hypersensitivity is induced in cattle PBMC during Bluetongue virus Taiwan Isolate infection
Publication date: Available online 21 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Jia-Ling Yang, Chia-Yi Chang, Well Chia-Wei Yen, Lenny Hao-Che Yen, Chia-Chi Wang, Fun-In Wang (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 23, 2020 Category: Veterinary Research Source Type: research

IgE sensitivity to Malassezia pachydermatis and mite allergens in dogs with atopic dermatitis
Publication date: Available online 21 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Hironobu Ishimaru, Noriaki Okamoto, Masato Fujimura, Kazuki Miyaji, Hidekatsu Shimakura, Yukari Takase, Keijiro Mizukami, Jumpei Uchiyama, Douglas J. DeBoer, Masahiro Sakaguchi (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 21, 2020 Category: Veterinary Research Source Type: research

Glycolysis and mitochondrial function regulate the radical oxygen species production induced by platelet-activating factor in bovine polymorphonuclear leukocytes
Publication date: Available online 21 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): John Quiroga, Pablo Alarcón, Carolina Manosalva, Anja Taubert, Carlos Hermosilla, María Angélica Hidalgo, María Daniella Carretta, Rafael Agustín Burgos (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 21, 2020 Category: Veterinary Research Source Type: research

The IFN-γ-induced immunoproteasome is suppressed in highly pathogenic porcine reproductive and respiratory syndrome virus-infected alveolar macrophages
Publication date: Available online 17 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Qiang Liu, Yu Yue-Yang, Huai-Yu Wang, Jing-Fei Wang, Xi-Jun He (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 17, 2020 Category: Veterinary Research Source Type: research

Variability in peripheral blood enrichment techniques can alter equine leukocyte cellularity, viability and function
Publication date: Available online 13 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Chase Connelly, Natalie A. Norton, David J Hurley, Kelsey A. Hart, Kristina Meichner, Robert M. Gogal (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 14, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: June 2020Source: Veterinary Immunology and Immunopathology, Volume 224Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 13, 2020 Category: Veterinary Research Source Type: research

Immunomodulatory effect of ginseng stem-leaf saponins and selenium on Harderian gland in immunization of chickens to Newcastle disease vaccine
Publication date: Available online 12 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Xiaodan Ma, Xiaoqing Chi, Lijia Yuan, Yuemin Wang, Zoushuyi Li, Wei Xu, Zahid Iqbal Rajput, Songhua Hu (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 13, 2020 Category: Veterinary Research Source Type: research

Alterations of peripheral gene expression in response to lipopolysaccharide-induced synovitis as a model for inflammation in horses
Publication date: Available online 11 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Allen E. Page, Emma Adam, John C. Stewart, Christopher Gonzales, Virginia Barker, David W. Horohov (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 11, 2020 Category: Veterinary Research Source Type: research

Comparison of Sheep, Goats, and Calves as Infection Models for Mycobacterium avium subsp. paratuberculosis
Publication date: Available online 5 May 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Judith R. Stabel, John P. Bannantine, Jesse M. Hostetter (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 5, 2020 Category: Veterinary Research Source Type: research

In vitro characterization and immunogenicity of chitosan nanoparticles loaded with native and inactivated extracellular proteins from a field strain of Clostridium perfringens associated with necrotic enteritis
Publication date: Available online 30 April 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Gabriel Akerele, Nour Ramadan, Sankar Renu, Gourapura J. Renukaradhya, Revathi Shanmugasundaram, Ramesh K Selvaraj (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - May 1, 2020 Category: Veterinary Research Source Type: research

Immune response and onset of protection from Bovine viral diarrhea virus 2 infection induced by modified-live virus vaccination concurrent with injectable trace minerals administration in newly received beef calves
Publication date: Available online 27 April 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): João H.J. Bittar, Roberto A. Palomares, David J. Hurley, Alejandro Hoyos-Jaramillo, Adriana Rodriguez, Agne Stoskute, Brianna Hamrick, Natalie Norton, Morgan Adkins, Jeremiah T. Saliki, Susan Sanchez, Kelsey Lauber (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - April 28, 2020 Category: Veterinary Research Source Type: research

Efficacy of fungal immunomodulatory protein to promote swine immune responses against porcine reproductive and respiratory syndrome virus infection
Publication date: Available online 27 April 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Fu-Hsiang Hou, Min-Yuan Chia, Jiunn-Wang Liao, Han-Ping Chung, Wei-Cheng Lee (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - April 28, 2020 Category: Veterinary Research Source Type: research

Measurement of the concentration of serum soluble interleukin-2 receptor alpha chain in dogs with lymphoma
Publication date: Available online 28 April 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Noriyuki Mizutani, Yuko Goto-Koshino, Keigo Kurata, Aki Fujiwara-Igarashi, Masahiro Sakaguchi, Minoru Asada, Koichi Ohno, Hajime Tsujimoto (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - April 28, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: May 2020Source: Veterinary Immunology and Immunopathology, Volume 223Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - April 22, 2020 Category: Veterinary Research Source Type: research

Ovine C-type lectin receptor hFc-fusion protein library – a novel platform to screen for host-pathogen interactions
Publication date: Available online 18 April 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Dimitri L. Lindenwald, João T. Monteiro, Silke Rautenschlein, Jochen Meens, Klaus Jung, Stefanie C. Becker, Bernd Lepenies (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - April 19, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: April 2020Source: Veterinary Immunology and Immunopathology, Volume 222Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 25, 2020 Category: Veterinary Research Source Type: research

CellTrace Violet™ inhibits equine lymphocyte proliferation
Publication date: Available online 18 March 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): J. Lacy Kamm, Natalie A. Parlane, Christopher B. Riley, Erica K. Gee, Joanna M. Roberts, C. Wayne McIlwraith (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 19, 2020 Category: Veterinary Research Source Type: research

Phenotypic characterization of equine monocyte-derived dendritic cells generated ex vivo utilizing commercially available serum-free medium
Publication date: Available online 17 March 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Brina S. Lopez, David J. Hurley, Shyla Giancola, Steeve Giguère, M. Julia. B. Felippe, Kelsey A. Hart (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 18, 2020 Category: Veterinary Research Source Type: research

Immunopathological characterization of red focal changes in Atlantic salmon (Salmo salar) white muscle
Publication date: Available online 12 March 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Håvard Bjørgen, Subramani Kumar, Gjermund Gunnes, Charles McL. Press, Espen Rimstad, Erling Olaf Koppang (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 13, 2020 Category: Veterinary Research Source Type: research

T cell epitope content comparison (EpiCC) analysis demonstrates a bivalent PCV2 vaccine has greater T cell epitope overlap with field strains than monovalent PCV2 vaccines
Publication date: Available online 6 March 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Meggan Bandrick, Andres H. Gutierrez, Prerak Desai, Gonzalo Rincon, William D. Martin, Frances E. Terry, Anne S. De Groot, Dennis L. Foss (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 7, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: March 2020Source: Veterinary Immunology and Immunopathology, Volume 221Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 3, 2020 Category: Veterinary Research Source Type: research

Associations between circulating levels of natural antibodies, total serum immunoglobulins, and polymorphonuclear leukocyte function in early postpartum dairy cows
Publication date: Available online 26 February 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): T.H. Silva, M.L. Celestino, P.R. Menta, R.C. Neves, M.A. Ballou, V.S. Machado (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - February 27, 2020 Category: Veterinary Research Source Type: research

Measuring CMI responses using the PrimeFlow RNA assay: A new method of evaluating BVDV vaccination response in cattle
This study also demonstrated a decrease in the frequency and amount of BVDV in PBMCs, harvested from vaccinated calves and exposed to BVDV in vitro. Collectively data from this study highlights the association between an increase in IFN-γ and a decreased infection rate of isolated PBMC’s, based on the frequency and amount of BVDV positive cells following in vitro exposure. This new method combines not only the ability to evaluate cellular responses, but also the ability to understand potential antiviral properties associated with cellular responses. This is the first assay to describe and simultaneously measure...
Source: Veterinary Immunology and Immunopathology - February 16, 2020 Category: Veterinary Research Source Type: research

Measuring CMI responses using the PrimeFlow RNA assay; a new method of evaluating BVDV vaccination response in cattle
This study also demonstrated a decrease in the frequency and amount of BVDV in PBMCs, harvested from vaccinated calves and exposed to BVDV in vitro. Collectively data from this study highlights the association between an increase in IFN-γ and a decreased infection rate of isolated PBMC’s, based on the frequency and amount of BVDV positive cells following in vitro exposure. This new method combines not only the ability to evaluate cellular responses, but also the ability to understand potential antiviral properties associated with cellular responses. This is the first assay to describe and simultaneously measure...
Source: Veterinary Immunology and Immunopathology - February 12, 2020 Category: Veterinary Research Source Type: research

Application of the TruCulture® whole blood stimulation system for immune response profiling in cattle
This study demonstrates the optimisation of this commercially available assay for systemic immune phenotyping in cattle. The early immune response in Holstein-Friesian bull calves (n = 10) was assessed by haematology, flow cytometry and cytokine expression profiling after 24 hour ex-vivo PAMP (LPS, poly (I:C) and Zymosan) stimulation in TruCulture® tubes. A comparative analysis was also performed with a traditional whole blood stimulation assay and cell viability using both systems was also evaluated. Results: Supernatant collected from TruCulture® tubes showed a significant increase in IL-1&be...
Source: Veterinary Immunology and Immunopathology - February 12, 2020 Category: Veterinary Research Source Type: research

Editorial Board
Publication date: February 2020Source: Veterinary Immunology and Immunopathology, Volume 220Author(s): (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - February 5, 2020 Category: Veterinary Research Source Type: research

Memory B cells and tuberculosis
Publication date: Available online 2 February 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Konstantin P. Lyashchenko, H. Martin Vordermeier, W. Ray WatersAbstractImmunological memory is a central feature of adaptive immunity. Memory B cells are generated upon stimulation with antigen presented by follicular dendritic cells in the peripheral lymphoid tissues. This process typically involves class-switch recombination and somatic hypermutation and it can be dependent or independent on germinal centers or T cell help. The mature B cell memory pool is generally characterized by remarkable heterogeneity of fu...
Source: Veterinary Immunology and Immunopathology - February 4, 2020 Category: Veterinary Research Source Type: research

Identification of canine IgG and its subclasses, IgG1, IgG2, IgG3 and IgG4, by immunofixation and commercially available antisera
Publication date: March 2020Source: Veterinary Immunology and Immunopathology, Volume 221Author(s): Dillon Donaghy, A Russell MooreAbstractImmunofixation is a diagnostic and research tool used for characterizing the electrophoretic location of immunoglobulin fractions in serum and urine. Commercially available polyclonal antisera which discriminate two IgG subclasses (IgG1 and IgG2) are available and commonly used. More recently, four IgG subclasses have been defined in the dog based on cDNA data. Archived serum from 16 dogs with naturally occurring monoclonal or biclonal gammopathies were characterized using routine serum...
Source: Veterinary Immunology and Immunopathology - January 29, 2020 Category: Veterinary Research Source Type: research

Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population
Publication date: Available online 26 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Melissa H. Siard-Altman, Patricia A. Harris, Amber D. Moffett-Krotky, Joanne L. Ireland, Alejandra Betancourt, Virginia D. Barker, Kellie E. McMurry, Stephanie E. Reedy, Amanda A. AdamsAbstractSimilarly to aged humans, senior horses (≥20 years) exhibit chronic low-grade inflammation systemically, known as inflamm-aging. Inflamm-aging in the senior horse has been characterized by increased circulating inflammatory cytokines as well as increased inflammatory cytokine production by lymphocytes and monocytes in resp...
Source: Veterinary Immunology and Immunopathology - January 27, 2020 Category: Veterinary Research Source Type: research

Vincristine, carboplatin and cisplatin increase oxidative burst induced by paf in canine neutrophils
Publication date: Available online 24 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Nathalia Mendez, Pablo Alarcon, Catalina Millán, Rafael A. Burgos, Francisco J. Morera, Javier OjedaAbstractMyelosupression resulting from chemotherapy has been widely described in veterinary medicine; however, there is limited information relating to alterations in neutrophil function after chemotherapy in dogs with cancer. The aim of this study was to determine the non-proliferative effects of vincristine, carboplatin, and cisplatin on canine neutrophils by evaluating activation of oxidative and non-oxidat...
Source: Veterinary Immunology and Immunopathology - January 25, 2020 Category: Veterinary Research Source Type: research

Elevated circulating Th2 but not group 2 innate lymphoid cell responses characterize canine atopic dermatitis
Publication date: Available online 24 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Simon P. Früh, Mridusmita Saikia, Jeremy Eule, Christina A. Mazulis, Julia E. Miller, Joby M. Cowulich, Oyebola O. Oyesola, Lauren M. Webb, Seth A. Peng, Rebecca L. Cubitt, Charles G. Danko, William H. Miller, Elia D. Tait WojnoAbstractAtopic dermatitis (AD) is an allergic skin disease that causes significant morbidity and affects multiple species. AD is highly prevalent in companion dogs and the clinical management of the disease remains challenging. An improved understanding of the immunologic and genetic pa...
Source: Veterinary Immunology and Immunopathology - January 25, 2020 Category: Veterinary Research Source Type: research

Title: Identification of Canine IgG and its subclasses, IgG1, IgG2, IgG3 and IgG4, by Immunofixation and Commercially Available Antisera
Publication date: Available online 23 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Dillon Donaghy, A Russell MooreAbstractImmunofixation is a diagnostic and research tool used for characterizing the electrophoretic location of immunoglobulin fractions in serum and urine. Commercially available polyclonal antisera which discriminate two IgG subclasses (IgG1 and IgG2) are available and commonly used. More recently, four IgG subclasses have been defined in the dog based on cDNA data. Archived serum from 16 dogs with naturally occurring monoclonal or biclonal gammopathies were characterized using rou...
Source: Veterinary Immunology and Immunopathology - January 24, 2020 Category: Veterinary Research Source Type: research

Contribution of astrocytes and macrophage migration inhibitory factor to immune-mediated canine encephalitis caused by the distemper virus
Publication date: Available online 20 January 2020Source: Veterinary Immunology and ImmunopathologyAuthor(s): Tatianna F.S. De Nardo, Paulo H.L. Bertolo, Priscila A. Bernardes, Danísio P. Munari, Gisele F. Machado, Luciana S. Jardim, Pamela R.R. Moreira, Mayara C. Rosolem, Rosemeri O. VasconcelosABSTRACTMacrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that is produced by many cell types in situations of homeostasis or disease. One of its functions is to act as a proinflammatory molecule. In humans, several studies have shown that MIF levels become elevated in the serum, urine, cerebrospinal flu...
Source: Veterinary Immunology and Immunopathology - January 20, 2020 Category: Veterinary Research Source Type: research