Leadless pacemaker: Performance and complications
Traditional transvenous cardiac pacemakers have pitfalls due to lead- and device pocket-related complications. Leadless pacemakers were developed and introduced into clinical practice to overcome the shortcomings of traditional transvenous pacemakers. In this review, we provide a description of leadless pacemaker devices, and summarize existing data on device performance. We also describe associated complications during implantation procedure as well as during the follow up period. Although current generation devices are limited to single-chamber pacing, future generation devices are expected to progress to multi-chamber m...
Source: Trends in Cardiovascular Medicine - August 9, 2017 Category: Cardiology Authors: Justin Z. Lee, Siva K. Mulpuru, Win K. Shen Source Type: research

Wearable Technology for Cardiology: An Update and Framework for the Future
The field of cardiology has long used wearable medical devices to monitor heart rate and rhythm. The past decade has seen the emergence of many new wearable devices, including several that have been widely adopted by both physicians and consumers. In this review, we discuss existing and forthcoming devices designed to measure activity, heart rate, heart rhythm and thoracic fluid. We also offer several frameworks to classify and better understand wearable devices, such that we may weigh their potential benefit in improving healthcare with the many challenges that must be addressed to reap these benefits. (Source: Trends in ...
Source: Trends in Cardiovascular Medicine - August 9, 2017 Category: Cardiology Authors: Joshua M. Pevnick, Kade Birkeland, Raymond Zimmer, Yaron Elad, Ilan Kedan Source Type: research

Ecology of the cardiovascular system: A focus on air-related environmental factors
We report first influences of air related environmental factors.Air temperature has a strong influence on cardiovascular mortality characterized by a V-like relationship confirming that both cold and hot periods have negative cardiovascular impacts. Furthermore, dynamic changes in temperature are likely more important than the absolute air temperature level. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - August 4, 2017 Category: Cardiology Authors: J.F. Argacha, T. Bourdrel, P. van de Borne Source Type: research

Effect of age and gender on the QTc-interval in healthy individuals and patients with Long-QT syndrome
Age- and gender related differences in QTc-interval are most likely the result of changes in sex-specific hormones. Although the exact mechanisms and pathophysiology of sex hormones on the QTc-interval are not known, testosterone appears to shorten the QTc-interval. In females, however, there is a more complex interaction between progesterone and estrogen. In patients with an impaired repolarization, such as Long-QT syndrome (LQTS), the effect of these sex hormones on the QTc-interval is more pronounced with a differing sensitivity between the LQTS genotypes. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - August 3, 2017 Category: Cardiology Authors: A. Suzanne Vink, Sally-Ann B. Clur, Arthur A.M. Wilde, Nico A. Blom Source Type: research

Predicting Death after Acute Myocardial Infarction
Recognizing and understanding the risk factors for mortality after acute myocardial infarction (AMI) provides clinicians and patients important information to determine prognosis and guide treatment. Most risk stratification models use demographic and clinical information that exists prior to hospitalization plus clinical presentation characteristics to estimate a patient's risk of mortality. In this review, we summarize the most important risk factors and discuss current models to predict mortality. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - August 2, 2017 Category: Cardiology Authors: Yulanka Castro-Dominguez, Kumar Dharmarajan, Robert L McNamara Source Type: research

Atrial arrhythmias after lung transplantation
In this report, we review the incidence and risk factors of post lung transplant AA, their pathogenesis and their impact on short and longer term outcomes. Pharmacological management options are reviewed. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 31, 2017 Category: Cardiology Authors: Henri Roukoz, David G. Benditt Source Type: research

CredibleMeds.org: What does it offer?
Since the 1990's, when numerous non-cardiac drugs were first recognized to have the potential to prolong the QT interval and cause torsades de pointes(TdP), clinicians, drug regulators, drug developers and clinical investigators have become aware of the complexities of assessing evidence and determining TdP causality for the many drugs being marketed or under development. To facilitate better understanding, the Arizona Center for Education and Research on Therapeutics, known as AZCERT, has developed the CredibleMeds.org website which includes QTdrugs, a listing of over 220 drugs placed in four risk categories based on thei...
Source: Trends in Cardiovascular Medicine - July 31, 2017 Category: Cardiology Authors: Raymond L. Woosley, Kristin Black, C. William Heise, Klaus Romero Source Type: research

Editorial commentary: Burnout in cardiology —Going to the heart of the misunderstanding
Burnout has been defined as a work-induced syndrome combining emotional exhaustion, depersonalization, and a sense of reduced personal accomplishment. Over the last years, the burnout phenomenon has elicited growing interest among the medical community. Studies seeking to estimate the prevalence of burnout among physicians, across various specialties and geographic areas, have multiplied. Such studies have generally yielded alarming results, giving rise to numerous calls for action. In their review, Panagioti et al. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 28, 2017 Category: Cardiology Authors: Renzo Bianchi, Eric Laurent Source Type: research

Burnout in cardiology: Going to the heart of the misunderstanding
Burnout has been defined as a work-induced syndrome combining emotional exhaustion, depersonalization, and a sense of reduced personal accomplishment. Over the last years, the burnout phenomenon has elicited growing interest among the medical community. Studies seeking to estimate the prevalence of burnout among physicians, across various specialties and geographic areas, have multiplied. Such studies have generally yielded alarming results, giving rise to numerous calls for action. In their review, Panagioti et al. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 28, 2017 Category: Cardiology Authors: Renzo Bianchi, Eric Laurent Source Type: research

Editorial Commentary: Clinical management of cardiovascular disease in HIV-infected patients
Human immunodeficiency virus (HIV) is no longer a deadly disease, but is now a chronic condition since the introduction of antiretroviral therapy (ART) [1]. Cardiovascular disease (CVD), specifically coronary artery disease, is becoming a significant health burden in HIV-infected (HIV+) patients. Our current understanding of the mechanisms underlying HIV-associated CVD is largely obtained from clinical observations [1]. ART treatment suppresses, but does not eradicate HIV. Extensive clinical evidence indicates that well-controlled HIV infection with or without ART (e.g., in HIV+ patients or HIV+ elite controllers) accelera...
Source: Trends in Cardiovascular Medicine - July 21, 2017 Category: Cardiology Authors: Alison Kearns, Tricia H. Burdo, Xuebin Qin Source Type: research

Clinical management of cardiovascular disease in HIV-infected patients
Human immunodeficiency virus (HIV) is no longer a deadly disease, but is now a chronic condition since the introduction of antiretroviral therapy (ART) [1]. Cardiovascular disease (CVD), specifically coronary artery disease, is becoming a significant health burden in HIV-infected (HIV+) patients. Our current understanding of the mechanisms underlying HIV-associated CVD is largely obtained from clinical observations [1]. ART treatment suppresses, but does not eradicate HIV. Extensive clinical evidence indicates that well-controlled HIV infection with or without ART (eg. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 21, 2017 Category: Cardiology Authors: Alison Kearns, Tricia H. Burdo, Xuebin Qin Source Type: research

Editorial Board
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 20, 2017 Category: Cardiology Source Type: research

Table of Contents
(Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 20, 2017 Category: Cardiology Source Type: research

Editorial commentary: Cardiac amyloidosis —Reversing the mindset and the cardiomyopathy
Cardiac amyloidosis has an unfortunate historical reputation as an uncommon disease with a poor prognosis and no treatment options. Anecdotally, this has led to an under-diagnosis and under-referral of patients. Recently, interest from the heart failure and cardiac imaging communities has led to an increase in recognition through multimodality imaging, while pharmaceutical companies have several novel treatment options in clinical trials for both light chain (AL) and transthyretin (ATTR) amyloidosis. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 17, 2017 Category: Cardiology Authors: Brett W. Sperry Source Type: research

Editorial commentary: Arrhythmias in patients with left ventricular assist devices: Pump fixed; rhythm … not so much
Left ventricular assist devices (LVADs) provide great benefit to patients with advanced systolic heart failure, including those awaiting heart transplantation. As there is a limited supply of donor hearts, increasing numbers of patients are supported by LVAD therapy for prolonged periods. As with most advances, LVADs carry with them both benefits and challenges. (Source: Trends in Cardiovascular Medicine)
Source: Trends in Cardiovascular Medicine - July 17, 2017 Category: Cardiology Authors: Daniel P. Morin Source Type: research