The effect of systematic conversion to generic Mycophenolate mofetil (MMF) in kidney transplantation;A single center clinical experience from Japan.
Recently, more and more generic drugs have been used for immunosuppressive drugs in the field of organ transplantation. Some reports have indicated that blood concentration of most generic drugs is difficult to maintain stability, and it may cause the difference in graft survival of transplanted organs between original drugs and generic drugs. In this article, we report the cases could not maintain blood concentration of generic drugs of mycophenolate mofetil (MMF). (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 3, 2018 Category: Transplant Surgery Authors: Hajime Hirano, Tomohisa Matsunaga, Ryouichi Maenosono, Shunri Taniguchi, Hirofumi Uehara, Hayahito Nomi, Yusuke Kano, Yuya Fujiwara, Atsushi Ichihashi, Daisuke Kobayashi, Takeshi Tsutsumi, Kazumasa Komura, Naokazu Ibuki, Taruo Inamoto, Hideki Matsumura, A Source Type: research
Identification of the subsets of IL-10 producing-regulatory B cells in the course of tolerance induction and maintenance in islet allotransplantation
In this study, we aimed to detect the subsets of the Bregs possessing the ability to produce IL-10 in the early stage and tolerance maintenance stage of allogeneic islet transplantation treated by dual anti-CD45RB/anti-TIM-1. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 3, 2018 Category: Transplant Surgery Authors: S. Li, X. Li, M. Yang, L. Wei, L. Wei, S. Deng, G.Zhao Source Type: research
Infusion of lymphocytes treated with 8-methoxypsoralen and ultraviolet A light induces CD19+IL-10+ regulatory B cells and promotes skin allograft survival
Extracorporeal photopheresis (ECP) represents an alternative to immunosuppression, as a means of reducing rejection after thoracic organ transplantation. The mechanism by which ECP exerts its protective effects, until now, has remained elusive. Infusion of ECP-treated splenic lymphocytes (PUVA-SP) can induce CD4+CD25highFoxp3+ regulatory T cells. However, the regulatory effect of PUVA-SP on B cells remains poorly understood. In the present study, we measured IL-10 secretion from CD19+ B cells of peripheral blood mononuclear cells. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 3, 2018 Category: Transplant Surgery Authors: YuXiang Wei, Li Xiao, Bin Sun, BingYi Shi Source Type: research
Combined liver-kidney transplantation in children: single center experiences and long-term results
Combined liver-kidney transplantation (CLKT) is a rare procedure in pediatric patients, in which liver and kidney from one donor are transplanted to a recipient during single operation. The aim of our study was the retrospective analysis of indications and results of CLKT in children (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 2, 2018 Category: Transplant Surgery Authors: M. Szymczak, P. Kalici ński, M. Markiewicz-Kijewska, G. Kowalewski, D. Broniszczak, H. Ismail, M. Stefanowicz, A. Kowalski, J. Rubik, I. Jankowska, B. Piątosa, J. Teisseyre, R. Grenda Source Type: research
Graft Contrast –Induced Nephropathy Caused by Prerenal Transplant Computed Tomography: A Case Report
We report a case of posttransplant contrast-induced nephropathy (CIN) that occurred after performing computed tomography (CT) scanning for pretransplant cardiac and vascular evaluation. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: S.D. Hwang, K.-M. Park, S.W. Lee, J.-Y. Han, M.-J. Kim, J.H. Song Tags: Asian Transplantation Week 2017 Source Type: research
Efficacy and Safety of Induction Therapy in Kidney Transplantation: A Network Meta-Analysis
Rejection and infection can occur after kidney transplantation and are important factors in preserving graft kidney function. The use of immunosuppressant agents in transplantation is therefore important, and the question of which induction therapy should be used as an immunosuppressant is controversial. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: S.D. Hwang, J.H. Lee, S.W. Lee, K.-M. Park, J.K. Kim, M.-J. Kim, J.H. Song Tags: Asian Transplantation Week 2017 Source Type: research
CYP3A5*3 Genetic Polymorphism and Tacrolimus Concentration in Myanmar Renal Transplant Patients
Genetic polymorphism is an important factor that influences tacrolimus concentrations and has the potential to predict the optimal dosage of tacrolimus in personalized medicine. Tacrolimus, a drug of narrow therapeutic index, is used in renal transplant recipients as an immunosuppressant agent. It is a substrate of cytochrome P450 3A (CYP3A) and has highly variable pharmacokinetic parameters. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: Y.Y. Htun, H.K. Swe, T.M. Saw Tags: Asian Transplantation Week 2017 Source Type: research
Cycling of Dexmedetomidine May Prevent Delirium After Liver Transplantation
This study found that dexmedetomidine cycling may prevent delirium by restoration of the circadian rhythm. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: K.S. Hong, N.R. Kim, S.H. Song, G. Hong Tags: Asian Transplantation Week 2017 Source Type: research
Application of the Revised Cardiac Risk Index to the Model for End-Stage Liver Disease Score Improves the Prediction of Cardiac Events in Patients Undergoing Liver Transplantation
Although the revised cardiac risk index (RCRI) is a useful tool for estimating the risk of postoperative cardiac events, whether it improves the prediction of cardiac events in patients undergoing liver transplantation (LT) has not been sufficiently demonstrated. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: Y.-S. Park, Y.-J. Moon, I.-G. Jun, J.-G. Song, G.-S. Hwang Tags: Asian Transplantation Week 2017 Source Type: research
Changing Paradigm in the Surgical Management of Hepatocellular Carcinoma With Salvage Transplantation
The objective of this study was to compare the long-term outcomes of primary and salvage liver transplantation for patients with hepatocellular carcinoma (HCC). (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: K.W. Ma, A.C.Y. Chan, B.W.H. She, K.S.H. Chok, T.T. Cheung, J.W.C. Dai, J.Y.Y. Fung, C.M. Lo Tags: Asian Transplantation Week 2017 Source Type: research
Duodenal Ulcer as a Postoperative Complication in the Donor in Living-Donor Liver Transplantation
Donor safety is one of the most important factors in living-donor liver transplantation. Duodenal ulcer (DU) is a common postoperative complication. Here we aimed to reveal the risk factors associated with postoperative DU in the donors. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: M. Kadohisa, Y. Sugawara, K. Shimata, S. Kawabata, Y. Narita, K. Uto, D. Yoshii, S. Hayashida, Y. Oya, H. Yamamoto, H. Yamamoto, Y. Inomata, T. Hibi Tags: Asian Transplantation Week 2017 Source Type: research
Is the Clinical Outcome Good or Bad in Patients Hospitalized Within 1 Year After Kidney Transplantation?
Although the hospitalization rate at early period of kidney transplantation (KT) is still high, the association between the hospitalization within 1 year after KT and graft survival is unclear. We investigated the incidence and causes of hospitalization and clinical outcome of the patients hospitalized within 1 year after KT. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: W.Y. Park, S.S. Kang, K. Jin, S.B. Park, S. Han Tags: Asian Transplantation Week 2017 Source Type: research
Predictive Factors of Liver Dysfunction After Right Hemihepatectomy for Adult Living Donor Liver Transplantation
Living liver donors represent a special group of patients. They are healthy individuals who are exposed to a major surgery, in which the dominant liver proportion is extracted as a graft. Of all potential donor-related morbidities, posthepatectomy liver dysfunction (PHLD) is the most significant as it may be directly related to donor mortality. We aimed to review our data of adult living donor liver transplantation (LDLT) utilizing the right hemiliver grafts to determine the incidence and potential predictors for the development of PHLD, defined according to the International Study Group of Liver Surgery. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: M. Elshoubary, A. Shehta, T. Salah, A.M. Sultan, A.M. Yassen, M. Abdulrazek, E.A. El-Magd, A.N. Elghawalby, U. Shiha, M. Elmorshedi, M. Elsadany, E. Abdelkhalek, O. Fathy, M.A. Wahab Tags: Asian Transplantation Week 2017 Source Type: research
Urinary Liver Type Fatty Acid Binding Protein Is Negatively Associated With Estimated Glomerular Filtration Rate in Renal Transplant Recipients With Graft Loss
Liver type fatty acid binding protein (L-FABP) is abundant not only in the liver but also in the kidney and is excreted in urine. Its primary function is to facilitate intracellular long chain fatty acid transport and it might also act as an endogenous antioxidant molecular. The purpose of this study was to investigate whether plasma or urinary L-FABP levels were associated with graft function in renal transplant recipients. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: Y.-C. Huang, Y.-S. Chang, C.-C. Chen, S.-F. Tsai, T.-M. Yu, M.-J. Wu, C.-H. Chen Tags: Asian Transplantation Week 2017 Source Type: research
How to Reconstruct Middle Hepatic Vein Branches With Explanted Portal Vein and Inferior Mesenteric Vein Graft: A Case Report
We report the technique of using explanted portal vein and inferior mesenteric vein graft in sequential fashion. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: S. Junrungsee, W. Lapisatepun, A. Chotirosniramit, T. Sandhu, K. Udomsin, W. Ko-iam, P. Chanthima, W. Lapisatepun, S. Boonsri, S. Lorsomradee Tags: Asian Transplantation Week 2017 Source Type: research
