Analysis of Follow ‐Up Methods of Vascular Access and Patient Outcomes in Hemodialysis at a Tertiary Care Hospital in China
Abstract Arteriovenous fistula is the preferred option for vascular access in hemodialysis patients. The aim of this study was to assess different follow‐up methods for hemodialysis patients in our hemodialysis center in China. A cohort of 124 patients with stage 3 chronic kidney disease was recruited and double‐blind randomly assigned into two groups. Patients in Group A received phone calls to schedule their next consultation a week in advance. Patients in Group B scheduled their next appointment at the end of each visit. A total of 116 patients were included in the study and eight dropped out. Twenty‐seven patient...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Ying Zhang, Xianglei Kong, Lijun Tang, Yong Wei, Dongmei Xu Tags: Original Article Source Type: research

Involvement of p38MAPK in Impaired Neutrophil Bactericidal Activity of Hemodialysis Patients
Abstract Mortality from infections has been reported to be higher in hemodialysis (HD) patients. Although dysfunction of neutrophils against bacterial infection was reported in HD patients, the precise mechanism remains to be clarified. We therefore examined the impacts of neutrophil inflammatory signaling on bactericidal activity in HD patients. Comprehensive analyses of intracellular signalings were performed in whole blood of HD patients and control using a microarray system. To confirm the contribution of the signaling to bactericidal activity in neutrophils, we examined the phosphorylation, bacterial killing function,...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Yasutaka Kamikawa, Norihiko Sakai, Taito Miyake, Akihiro Sagara, Yasuyuki Shinozaki, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Ryu Imamura, Takashi Suda, Shuichi Kaneko, Takashi Wada Tags: Original Article Source Type: research

Author ’s Reply to Oka and Colleagues
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Kojiro Nagai, Kenji Tsuchida, Noriyuki Ishihara, Naoto Minagawa, Go Ichien, Satoshi Yamada, Daisuke Hirose, Hiroyuki Michiwaki, Hiro ‐omi Kanayama, Toshio Doi, Jun Minakuchi Tags: Letter to the Editor Source Type: research

Authors Should Pay Attention to the Confounding by Indication of Observational Study Using Propensity Score
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Yoshinari Oka, Hiroaki Matsuda, Masashi Miyazaki Tags: Letter to the Editor Source Type: research

Barriers to Effective Case Management for Disabled Patients on Hemodialysis
Abstract The present study examined the performance level and its related factors on the process of case management for disabled patients on hemodialysis. Case management performance was evaluated at three stages: patient assessment, making a care plan, and monitoring/evaluation. Candidates for targeting the factors relating to performance included four dimensions: nursing care level, physical malfunction, cognitive malfunction, and barriers to service were used as patient factors; the period of case management for the patient and the knowledge of dialysis emerged as case manager factors; work load was included as an organ...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Hidehiro Sugisawa, Yumiko Shimizu, Tamaki Kumagai, Hiroaki Sugisaki, Seiji Ohira, Toshio Shinoda Tags: Original Article Source Type: research

Aldosterone and Insulin Resistance: Vicious Combination in Patients on Maintenance Hemodialysis
In conclusion, in hemodialysis patients, aldosterone levels and insulin resistance are closely interrelated and the constellation of the two is related to severe cardiovascular tissue damages. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Shu Wakino, Hitoshi Minakuchi, Keiko Miya, Norimichi Takamatsu, Hiroaki Tada, Erina Tani, Hajime Inamoto, Jun Minakuchi, Shu Kawashima, Hiroshi Itoh Tags: Original Article Source Type: research

Targeting Albumin Binding Function as a Therapy Goal in Liver Failure: Development of a Novel Adsorbent for Albumin Dialysis
In this study, we introduced a new adsorbent material for albumin dialysis treatments that improves albumin binding capacity. The new charcoal adsorbent was developed by an evolutionary test schedule. Batch testing of charcoals was performed as steady‐state experiments. The charcoal reflecting the highest increase in albumin binding capacity was then introduced to kinetic models: Perfusion tests were designed to evaluate adsorption capacity and kinetics for liver failure marker toxins. A dynamic recirculation model for liver failure was used for upscaling and comparison against conventional MARS adsorbents as the gold st...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Adrian Dominik, Jan Stange, Anja K Baumann, Claudia Pfensig, Matthias Suraj, Badr Ibrahim, Martin Eggert Tags: Original Article Source Type: research

Atypical Hemolytic Uremic Syndrome: A Meta ‐Analysis of Case Reports Confirms the Prevalence of Genetic Mutations and the Shift of Treatment Regimens
Abstract Atypical hemolytic uremic syndrome (aHUS) is a rare life‐threatening thrombotic microangiopathy (TMA) affecting multiple organ systems. Recently, aHUS has been shown to be associated with uncontrolled complement activation due to mutations in the alternative pathway of complement components paving the way for targeted drug therapy. By meta‐analysis of case reports, we discuss the impact of new treatment strategies on the resolution time of aHUS symptoms and mortality, and the distribution of genetic mutations. A PubMed/Medline search was conducted for “atypical hemolytic uremic syndrome” case reports publi...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Vinod Krishnappa, Mohit Gupta, Mohamed Elrifai, Bahar Moftakhar, Michael J Ensley, Tushar J Vachharajani, Sidharth Kumar Sethi, Rupesh Raina Tags: Original Article Source Type: research

Role of Plasmapheresis in the Management of Acute Kidney Injury in Patients With Multiple Myeloma: Should We Abandon It?
Abstract The aim of the current study was to determine whether plasmapheresis in combination with chemotherapy could significantly remove free light chains (FLC) in multiple myeloma (MM) patients with acute kidney injury (AKI) and therefore improve renal recovery and patient survival. During the study period, 29 patients with MM and AKI presented to our unit and were treated with two different therapy modalities (plasmapheresis with chemotherapy or bortezomib). At the end of treatment, a significant decrease of FLCs was present in the group treated with plasmapheresis compared to the bortezomib group. Patients treated with...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Vedran Premuzic, Josip Batinic, Pavle Roncevic, Nikolina Basic ‐Jukic, Damir Nemet, Bojan Jelakovic Tags: Original Article Source Type: research

Increased Serum Level of IGF ‐1 Correlates With Better Cognitive Status in End‐Stage Renal Disease Patients Undergoing Hemodialysis
This study included 93 ESRD patients undergoing hemodialysis two or three times a week in three centers for hemodialysis in Montenegro. The cognitive status of patients was assessed using the mini mental score examination (MMSE) test. All 93 patients have been divided into three groups according to the results of MMSE. Patients in the first group had severe cognitive impairment and MMSE score below 17 (26.88%), patients in the second group with MMSE score 18–23 had moderate cognitive impairment (40.86%) and third group of patients have MMSE >24 and no cognitive impairment (32.26%). There were no significant difference...
Source: Therapeutic Apheresis and Dialysis - December 1, 2017 Category: Hematology Authors: Vladimir Prelevic, Danilo Radunovic, Tanja Antunovic, Marina Ratkovic, Najdana Gligorovic ‐Bahranovic, Branka Gledovic, Snezana Vujosevic, Mirjana Nedovic‐Vukovic, Nikolina Basic‐Jukic Tags: Original Article Source Type: research

Quality of Life and Depression Among Mexican Americans on Hemodialysis: A Preliminary Report
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 28, 2017 Category: Hematology Source Type: research

Peritoneal Dialysis Related Peritonitis by Sphingomonas Paucimobilis
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 28, 2017 Category: Hematology Source Type: research

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Therapeutic Apheresis and Dialysis, Ahead of Print. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 28, 2017 Category: Hematology Source Type: research

Peritoneal Dialysis Related Peritonitis by Sphingomonas Paucimobilis
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 28, 2017 Category: Hematology Authors: Fatih Y ılmaz, Feyza Bora, Fevzi Ersoy Tags: Letter to the Editor Source Type: research