Theoretical Biology and Medical Modelling This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

MiStImm: an agent-based simulation tool to study the self-nonself discrimination of the adaptive immune response
There is an increasing need for complex computational models to perform in silico experiments as an adjunct to in vitro and in vivo experiments in immunology. We introduce Microscopic Stochastic Immune System ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - May 2, 2019 Category: Biomedical Science Authors: Csaba Kerepesi, Tibor Bak ács and Tamás Szabados Tags: Software Source Type: research

Gene regulatory networks on transfer entropy (GRNTE): a novel approach to reconstruct gene regulatory interactions applied to a case study for the plant pathogen Phytophthora infestans
The increasing amounts of genomics data have helped in the understanding of the molecular dynamics of complex systems such as plant and animal diseases. However, transcriptional regulation, although playing a ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - April 9, 2019 Category: Biomedical Science Authors: Juan Camilo Castro, Ivan Vald és, Laura Natalia Gonzalez-García, Giovanna Danies, Silvia Cañas, Flavia Vischi Winck, Carlos Eduardo Ñústez, Silvia Restrepo and Diego Mauricio Riaño-Pachón Tags: Research Source Type: research

Correction to: High resolution hemodynamic profiling of murine arteriovenous fistula using magnetic resonance imaging and computational fluid dynamics
After publication of the original article (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - April 9, 2019 Category: Biomedical Science Authors: Daniel Pike, Yan-Ting Shiu, Maheshika Somarathna, Lingling Guo, Tatyana Isayeva, John Totenhagen and Timmy Lee Tags: Correction Source Type: research

Quantifying heterogeneous contact patterns in Japan: a social contact survey
Social contact surveys can greatly help in quantifying the heterogeneous patterns of infectious disease transmission. The present study aimed to conduct a contact survey in Japan, offering estimates of contact... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 20, 2019 Category: Biomedical Science Authors: Lankeshwara Munasinghe, Yusuke Asai and Hiroshi Nishiura Tags: Research Source Type: research

Mathematical modeling of septic shock based on clinical data
Mathematical models of diseases may provide a unified approach for establishing effective treatment strategies based on fundamental pathophysiology. However, models that are useful for clinical practice must o... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 6, 2019 Category: Biomedical Science Authors: Yukihiro Yamanaka, Kenko Uchida, Momoka Akashi, Yuta Watanabe, Arino Yaguchi, Shuji Shimamoto, Shingo Shimoda, Hitoshi Yamada, Masashi Yamashita and Hidenori Kimura Tags: Research Source Type: research

How to eliminate taeniasis/cysticercosis: porcine vaccination and human chemotherapy (Part 2)
The application of effective vaccines against pig cysticercosis and mass chemotherapy against pig cysticercosis and human taeniasis have shown the feasibility of interrupting the parasite ’s life cycle in endem... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 26, 2019 Category: Biomedical Science Authors: Norma Y. S ánchez-Torres, Juan R. Bobadilla, Juan P. Laclette and Marco V. José Tags: Research Source Type: research

Analysis of the role of thrombomodulin in all-trans retinoic acid treatment of coagulation disorders in cancer patients
Clinical studies have shown that all-trans retinoic acid (RA), which is often used in treatment of cancer patients, improves hemostatic parameters and bleeding complications such as disseminated intravascular ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 14, 2019 Category: Biomedical Science Authors: Hamed Ghaffari, Jeffrey D. Varner and Linda R. Petzold Tags: Research Source Type: research

Modeling Clostridium difficile in a hospital setting: control and admissions of colonized and symptomatic patients
Clostridium difficile (C. difficile) infection is an important cause of healthcare-associated diarrhea. Several factors such as admission of colonized patients, levels of serum antibodies in patients, and control... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 31, 2019 Category: Biomedical Science Authors: Farida Chamchod and Prasit Palittapongarnpim Tags: Research Source Type: research

Assessing parameter identifiability in compartmental dynamic models using a computational approach: application to infectious disease transmission models
Mathematical modeling is now frequently used in outbreak investigations to understand underlying mechanisms of infectious disease dynamics, assess patterns in epidemiological data, and forecast the trajectory ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 14, 2019 Category: Biomedical Science Authors: Kimberlyn Roosa and Gerardo Chowell Tags: Research Source Type: research

Model based on GA and DNN for prediction of mRNA-Smad7 expression regulated by miRNAs in breast cancer
The Smad7 protein is negative regulator of the TGF- β signaling pathway, which is upregulated in patients with breast cancer. miRNAs regulate proteins expressions by arresting or degrading the mRNAs. The purpos... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 29, 2018 Category: Biomedical Science Authors: Edgar Manzanarez-Ozuna, Dora-Luz Flores, Everardo Guti érrez-López, David Cervantes and Patricia Juárez Tags: Research Source Type: research

Kinetic modeling of tumor regression incorporating the concept of cancer stem-like cells for patients with locally advanced lung cancer
Personalized medicine for patients receiving radiation therapy remains an elusive goal due, in part, to the limits in our understanding of the underlying mechanisms governing tumor response to radiation. The p... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 27, 2018 Category: Biomedical Science Authors: Hualiang Zhong, Stephen Brown, Suneetha Devpura, X. Allen Li and Indrin J. Chetty Tags: Research Source Type: research

Mathematical model of the life cycle of taenia-cysticercosis: transmission dynamics and chemotherapy (Part 1)
Taenia solium is the aetiological agent of human taeniasis, pig cysticercosis and human neurocysticercosis, which are serious public health problems, especially in developing countries. (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 19, 2018 Category: Biomedical Science Authors: Marco V. Jos é, Juan R. Bobadilla, Norma Y. Sánchez-Torres and Juan Pedro Laclette Tags: Research Source Type: research

A modified particle swarm optimization algorithm for parameter estimation of a biological system
Mathematical modeling has achieved a broad interest in the field of biology. These models represent the associations among the metabolism of the biological phenomenon with some mathematical equations such that... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 5, 2018 Category: Biomedical Science Authors: Raziyeh Mosayebi and Fariba Bahrami Tags: Research Source Type: research

Demographic supply-demand imbalance in industrial structure in the super-aged nation Japan
Japan has a rapidly decreasing population, with ultra-low fertility and extremely fast aging. The rapid dynamics constitute a warning that change in the industrial structure may be unable to meet the changing ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 1, 2018 Category: Biomedical Science Authors: Naoki Kishida and Hiroshi Nishiura Tags: Research Source Type: research

Novel neural network application for bacterial colony classification
Bacterial colony morphology is the first step of classifying the bacterial species before sending them to subsequent identification process with devices, such as VITEK 2 automated system and mass spectrometry ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 30, 2018 Category: Biomedical Science Authors: Lei Huang and Tong Wu Tags: Research Source Type: research