Effect of fentanyl on thermal and mechanical nociceptive thresholds in horses and estimation of anti-nociceptive plasma concentration
Publication date: Available online 31 May 2019Source: The Veterinary JournalAuthor(s): J. Echelmeyer, P.M. Taylor, K. Hopster, K. Rohn, J. Delarocque, S.B.R. KästnerAbstractThere are few investigations relating anti-nociception to plasma concentrations of fentanyl in horses. The study objective was to evaluate analgesic efficacy and duration in horses and determine the minimum anti-nociceptive plasma concentrations. Eight horses were treated with saline (P) and fentanyl (F2.5 = 2.5 µg/kg; F5 = 5 µg/kg; F10 = 10 µg/kg) given IV over 5 min, with a wash-out period of 10 days. To evaluate thermal (°C) ...
Source: The Veterinary Journal - June 1, 2019 Category: Veterinary Research Source Type: research
The utility of point-of-care ultrasound right-sided cardiac markers as a screening test for moderate to severe pulmonary hypertension in dogs
Publication date: Available online 31 May 2019Source: The Veterinary JournalAuthor(s): A.I. Vientós-Plotts, K.E. Wiggen, G.R. Lisciandro, C.R. ReineroAbstractDogs with respiratory disease can develop pulmonary hypertension (PH), a comorbid condition that can impact therapy and prognosis. Without confirmation using the criterion standard of echocardiography, this complication may be missed. Point-of-care ultrasound (POCUS) is a simple, non-invasive screening test that may suggest PH. It was hypothesized that in dogs POCUS right-sided cardiac markers (R-SCM) at the subxiphoid view would predict moderate to severe PH confirm...
Source: The Veterinary Journal - June 1, 2019 Category: Veterinary Research Source Type: research
Transrectal ultrasound of the combined thickness of the uterus and interplacentome region in healthy pregnant Holstein cows
Publication date: Available online 30 May 2019Source: The Veterinary JournalAuthor(s): Jennifer Koziol, George MooreAbstractCombined thickness of the uterus and placenta (CTUP) has been used for many years to assess fetal well-being and placental health in the mare and most recently the combined thickness of the uterus and interplacentome region (CTUIR) in water buffalo. The aim of this study was to develop normal reference ranges in regards to the CTUIR in 25 Holstein cows throughout pregnancy. The CTUIR was measured every 30 days from 60 days of gestation until 270 days of gestation. Measurements were obtained by transre...
Source: The Veterinary Journal - May 30, 2019 Category: Veterinary Research Source Type: research
Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs
Publication date: Available online 27 May 2019Source: The Veterinary JournalAuthor(s): L. Pelander, V. Brunchault, B. Buffin-Meyer, J. Klein, B. Breuil, P. Zürbig, P. Magalhães, W. Mullen, J. Elliott, H. Syme, J.P. Schanstra, J. Häggström, I. LjungvallAbstractChronic kidney disease (CKD) is clinically important in canine medicine. Current diagnostic tools lack sensitivity for detection of subclinical CKD. The aim of the present study was to evaluate urinary peptidome analysis for diagnosis of CKD in dogs. Capillary electrophoresis coupled to mass spectrometry analysis demonstrated presence of approximately 5400 peptide...
Source: The Veterinary Journal - May 28, 2019 Category: Veterinary Research Source Type: research
Hair cortisol concentration is inversely related to the severity of equine squamous gastric disease
Publication date: Available online 24 May 2019Source: The Veterinary JournalAuthor(s): Miguelita Prinsloo, Philip Hynd, Samantha Franklin, Sarah Weaver, Robin van den BoomAbstractEquine squamous gastric disease (ESGD) is common in horses and many factors, including stress, may play a role in lesion development. Hair cortisol concentration (HCC) provides a measure of medium to long-term stress and therefore, the relationship between HCC and ESGD was examined in this study. Hair samples were collected from 25 horses and gastroscopy was performed to determine the presence and severity of ESGD. Hair cortisol concentrations wer...
Source: The Veterinary Journal - May 25, 2019 Category: Veterinary Research Source Type: research
Effects of attenuated vaccine protocols against Salmonella Typhimurium on Salmonella serology in subclinically infected pig herds
Publication date: Available online 23 May 2019Source: The Veterinary JournalAuthor(s): L. Peeters, J. Dewulf, F. Boyen, C. Brossé, T. Vandersmissen, G. Rasschaert, M. Heyndrickx, M. Cargnel, F. Pasmans, D. MaesAbstractVaccination of pigs against Salmonella Typhimurium (S. Typhimurium) can be effective for the control of Salmonella infections at the farm level and reduce the risk of Salmonella contamination in the food chain. However, vaccination may interfere with herd serological status in serology-based Salmonella monitoring programs. The present study investigated the effects of an attenuated S. Typhimurium vaccine (Sa...
Source: The Veterinary Journal - May 24, 2019 Category: Veterinary Research Source Type: research
Corrigendum to: “Testing for food-specific antibodies in saliva and blood of food allergic and healthy dogs” [Vet. J. 245 (2019) 1–6]
Publication date: Available online 23 May 2019Source: The Veterinary JournalAuthor(s): L. Udraite Vovk, A. Watson, W.J. Dodds, C.J. Klinger, J. Classen, R.S. Mueller (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 24, 2019 Category: Veterinary Research Source Type: research
Implementation of high coverage mass rabies vaccination in rural Uganda using predominantly static point methodology
Publication date: Available online 23 May 2019Source: The Veterinary JournalAuthor(s): M.J. Evans, J.L. Burdon Bailey, F.E. Lohr, W. Opira, M. Migadde, A.D. Gibson, I.G. Handel, B.M. deC. Bronsvoort, R.J. Mellanby, L. Gamble, S. MazeriAbstractDespite successful eradication programmes in many regions, rabies remains responsible for approximately 60,000 human deaths annually, and no country in Africa is rabies-free. Dogs are the principal reservoir of the virus in Africa and the World Health Organisation recommends that at least 70% of the dog population be vaccinated in order to break the transmission cycle. Most attempts a...
Source: The Veterinary Journal - May 24, 2019 Category: Veterinary Research Source Type: research
Epileptic seizure frequency and semiology in dogs with idiopathic epilepsy after initiation of imepitoin or phenobarbital monotherapy
In this study, AEM-naïve DIE receiving imepitoin-monotherapy developed CS significantly more frequently and earlier in the course of the disease, and developed aggression and required earlier discontinuation of monotherapy than AEM-naïve DIE receiving phenobarbital-monotherapy. (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 24, 2019 Category: Veterinary Research Source Type: research
Duodenal expression of antimicrobial peptides in dogs with idiopathic inflammatory bowel disease and intestinal lymphoma
The objective of this study was to investigate the intestinal expression of AMPs in dogs with IBD or intestinal lymphoma. IBD was diagnosed in 44 dogs, small cell intestinal lymphoma in 25 dogs, and large cell intestinal lymphoma in 19 dogs. Twenty healthy beagles were used as normal controls. Duodenal mRNA expression of six representative AMPs ― lactoferrin, lysozyme, cathelicidin, secretory leukocyte peptidase inhibitor (SLPI), bactericidal/permeability increasing protein (BPI), and canine beta defensin (CBD103) ― was quantified by real-time reverse transcription polymerase chain reaction.The relative expression of B...
Source: The Veterinary Journal - May 22, 2019 Category: Veterinary Research Source Type: research
Editorial Board
Publication date: June 2019Source: The Veterinary Journal, Volume 248Author(s): (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 19, 2019 Category: Veterinary Research Source Type: research
Methods and basic concepts for microbiota assessment
The objective of this review is to describe some of the most common methods for characterization of microbial communities and to provide an overview of the basic concepts necessary for good interpretation of the research performed in this field. (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 15, 2019 Category: Veterinary Research Source Type: research
Performance comparison of 159 Thoroughbred racehorses and matched cohorts before and after desmotomy of the interspinous ligament
Publication date: Available online 11 May 2019Source: The Veterinary JournalAuthor(s): A.M. Derham, J.M. O’Leary, S.E. Connolly, J. Schumacher, G. KellyAbstractRacehorses may perform poorly because of impinging dorsal spinous processes (DSPs) of the thoracolumbar vertebrae. No study has looked objectively at the long-term outcome of racehorses undergoing desmotomy of the interspinous ligament as a treatment for horses with poor performance caused by impinging DSPs. The aim of this study was to examine objectively, by using pre-operative and post-operative racing records, the effectiveness of desmotomy of the interspinous...
Source: The Veterinary Journal - May 12, 2019 Category: Veterinary Research Source Type: research
Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas
Publication date: Available online 8 May 2019Source: The Veterinary JournalAuthor(s): J.G. Rushton, M. Korb, S. Kummer, U. Reichart, A. Fuchs-Baumgartinger, A. Tichy, B. NellAbstractFeline iris melanoma, the most common feline intraocular tumour, has a reported metastatic rate of 19–63%. However, there is a lack of knowledge about its molecular biology. Previous studies have reported that feline iris melanomas do not harbour mutations comparable to common mutations found in their human counterpart. Nevertheless, there are differences in the gene expression patterns. The aim of this study was to investigate the protein ex...
Source: The Veterinary Journal - May 10, 2019 Category: Veterinary Research Source Type: research
Occurrence of exercise-induced pulmonary haemorrhage in show jumping horses
In conclusion, pulmonary haemorrhage in jumping horses was associated with the level of performance. Further studies on the pathophysiology of exercise-induced pulmonary haemorrhage in this type of horses are required. (Source: The Veterinary Journal)
Source: The Veterinary Journal - May 7, 2019 Category: Veterinary Research Source Type: research
