Martha Wadsworth: battling social injustice for the sake of youth mental health
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Priya Venkatesan (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

Man on the moon
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Simon Guerrier (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

“Poor baby”: The Love Witch
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Laura Thomas (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

Notes on a Nervous Planet, Matt Haig. Canongate Books (2018), 320, £12.99, ISBN: 9781786892676
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Andrew Bianchi (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

Careless communities
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Talha Burki (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

Environmental risk factors and biomarkers for autism spectrum disorder: an umbrella review of the evidence
We examined small study effects and excess significance. We did analyses under credibility ceilings. This review is registered with PROSPERO, number CRD42018091704.Findings46 eligible articles yielded data on 67 environmental risk factors (544 212 cases, 81 708 787 individuals) and 52 biomarkers (15 614 cases, 15 433 controls). Evidence of association was convincing for maternal age of 35 years or over (relative risk [RR] 1·31, 95% CI 1·18–1·45), maternal chronic hypertension (odds ratio [OR] 1·48, 1·29–1·70), maternal gestational hypertension (OR 1·37,...
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

Tapering of SSRI treatment to mitigate withdrawal symptoms – Authors' reply
Publication date: July 2019Source: The Lancet Psychiatry, Volume 6, Issue 7Author(s): Mark Abie Horowitz, David Taylor (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 21, 2019 Category: Psychiatry Source Type: research

ADHD medication treatment and risk of psychosis
Publication date: Available online 17 June 2019Source: The Lancet PsychiatryAuthor(s): Lily Hechtman (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 18, 2019 Category: Psychiatry Source Type: research

Methylphenidate and the risk of psychosis in adolescents and young adults: a population-based cohort study
Publication date: Available online 17 June 2019Source: The Lancet PsychiatryAuthor(s): Chris Hollis, Qi Chen, Zheng Chang, Patrick D Quinn, Alexander Viktorin, Paul Lichtenstein, Brian D'Onofrio, Mikael Landén, Henrik LarssonSummaryBackgroundThere is a clinical concern that prescribing methylphenidate, the most common pharmacological treatment for attention-deficit hyperactivity disorder (ADHD), might increase the risk of psychotic events, particularly in young people with a history of psychosis. We aimed to determine whether the risk of psychotic events increases immediately after initiation of methylphenidate trea...
Source: The Lancet Psychiatry - June 18, 2019 Category: Psychiatry Source Type: research

Rising opioid-related deaths in England and Scotland must be recognised as a public health crisis
Publication date: Available online 11 June 2019Source: The Lancet PsychiatryAuthor(s): Jo Kimber, Matt Hickman, John Strang, Kyla Thomas, Sharon Hutchinson (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 12, 2019 Category: Psychiatry Source Type: research

A diversified theory of catatonia
Publication date: Available online 10 June 2019Source: The Lancet PsychiatryAuthor(s): Mark Oldham (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 11, 2019 Category: Psychiatry Source Type: research

Catatonia and the immune system: a review
Publication date: Available online 10 June 2019Source: The Lancet PsychiatryAuthor(s): Jonathan P Rogers, Thomas A Pollak, Graham Blackman, Anthony S DavidSummaryCatatonia is a psychomotor disorder featuring stupor, posturing, and echophenomena. This Series paper examines the evidence for immune dysregulation in catatonia. Activation of the innate immune system is associated with mutism, withdrawal, and psychomotor retardation, which constitute the neurovegetative features of catatonia. Evidence is sparse and conflicting for acute-phase activation in catatonia, and whether this feature is secondary to immobility is unclear...
Source: The Lancet Psychiatry - June 11, 2019 Category: Psychiatry Source Type: research

Structure and neural mechanisms of catatonia
Publication date: Available online 10 June 2019Source: The Lancet PsychiatryAuthor(s): Sebastian Walther, Katharina Stegmayer, Jo Ellen Wilson, Stephan HeckersSummaryCatatonia is a psychomotor syndrome associated with several psychiatric and medical conditions. Psychomotor signs range from stupor to agitation, and include pathognomonic features such as verbigeration and waxy flexibility. Disturbances of volition led to the classification of catatonia as a subtype of schizophrenia, but changes in nosology now recognise the high prevalence in mood disorders, overlap with delirium, and comorbidity with medical conditions. Ini...
Source: The Lancet Psychiatry - June 11, 2019 Category: Psychiatry Source Type: research

Correction to Lancet Psychiatry 2019; 6: 464
Publication date: Available online 7 June 2019Source: The Lancet PsychiatryAuthor(s): (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 8, 2019 Category: Psychiatry Source Type: research

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis
Publication date: Available online 6 June 2019Source: The Lancet PsychiatryAuthor(s): Toshi A Furukawa, Andrea Cipriani, Philip J Cowen, Stefan Leucht, Matthias Egger, Georgia SalantiSummaryBackgroundDepression is the single largest contributor to non-fatal health loss worldwide. Second-generation antidepressants are the first-line option for pharmacological management of depression. Optimising their use is crucial in reducing the burden of depression; however, debate about their dose dependency and their optimal target dose is ongoing. We have aimed to summarise the currently available best evidence to inform this clinica...
Source: The Lancet Psychiatry - June 7, 2019 Category: Psychiatry Source Type: research

Which antidepressant doses are optimal?
Publication date: Available online 6 June 2019Source: The Lancet PsychiatryAuthor(s): Fredrik Hieronymus (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 7, 2019 Category: Psychiatry Source Type: research

Prevalence of non-suicidal self-harm and service contact in England, 2000–14: repeated cross-sectional surveys of the general population
Publication date: Available online 4 June 2019Source: The Lancet PsychiatryAuthor(s): Sally McManus, David Gunnell, Claudia Cooper, Paul E Bebbington, Louise M Howard, Traolach Brugha, Rachel Jenkins, Angela Hassiotis, Scott Weich, Louis ApplebySummaryBackgroundThe number of people presenting to hospital emergency departments after self-harming has increased in England. However, most people who self-harm do not present to hospitals, so whether this rise reflects an increase in the prevalence of self-harm in the community is unknown. Also unknown is whether the prevalence of non-suicidal self-harm (NSSH) or suicidal self-ha...
Source: The Lancet Psychiatry - June 5, 2019 Category: Psychiatry Source Type: research

Responding to the rising prevalence of self-harm
Publication date: Available online 4 June 2019Source: The Lancet PsychiatryAuthor(s): Rohan Borschmann, Stuart A Kinner (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 5, 2019 Category: Psychiatry Source Type: research

Multiple adverse outcomes following first discharge from inpatient psychiatric care: a national cohort study
Publication date: Available online 3 June 2019Source: The Lancet PsychiatryAuthor(s): Florian Walter, Matthew J Carr, Pearl L H Mok, Sussie Antonsen, Carsten B Pedersen, Louis Appleby, Seena Fazel, Jenny Shaw, Roger T WebbSummaryBackgroundDischarged psychiatric inpatients are at elevated risk of serious adverse outcomes, but no previous study has comprehensively examined an array of multiple risks in a single cohort.MethodsWe used data from the Danish Civil Registration System to delineate a cohort of all individuals born in Denmark in 1967–2000, who were alive and residing in Denmark on their 15th birthday, and who ...
Source: The Lancet Psychiatry - June 5, 2019 Category: Psychiatry Source Type: research

A lifespan strategy to prevent adverse outcomes associated with psychiatric hospitalisation
Publication date: Available online 3 June 2019Source: The Lancet PsychiatryAuthor(s): Simone N Vigod, Paul A Kurdyak (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 5, 2019 Category: Psychiatry Source Type: research

Predatory journals in psychiatry
Publication date: Available online 30 May 2019Source: The Lancet PsychiatryAuthor(s): Jaafar Omer, Shvan H Mohammed, Rawezh Q Salih, Fahmi H Kakamad, Tomas M Mikael, Karukh K Mohammed, Masrur S Aziz, Dahat A Hussein, Goran A Qadr, Abdulwahid M Salih (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - June 1, 2019 Category: Psychiatry Source Type: research

Emerging challenges in pharmacotherapy research on attention-deficit hyperactivity disorder—outcome measures beyond symptom control and clinical trials
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Ian C K Wong, Tobias Banaschewski, Jan Buitelaar, Samuele Cortese, Manfred Döpfner, Emily Simonoff, David Coghill, European ADHD Guidelines GroupSummaryAlthough pharmacological therapies are recommended as a key component in the treatment of attention-deficit hyperactivity disorder, their use continues to prompt intense debate. Despite considerable research efforts, several gaps in the knowledge base and several questions over the quality of evidence exist. Particular issues surrounding pharmacological treatments include uncertaintie...
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Five years
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Niall Boyce, Joan Marsh, Dustin Graham (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Problems with the ICD-11 classification of personality disorder
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Jay Watts (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

High-potency cannabis and incident psychosis: correcting the causal assumption
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Nathan A Gillespie, Joelle A Pasman, Jorien L Treur, Eske M Derkes, Karin J H Verweij, Jacqueline M Vink (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

High-potency cannabis and incident psychosis: correcting the causal assumption
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Iris E Sommer, Wim van den Brink (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

High-potency cannabis and incident psychosis: correcting the causal assumption
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Clas Linnman (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

High-potency cannabis and incident psychosis: correcting the causal assumption – Authors' reply
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Marta Di Forti, Craig Morgan, Jean-Paul Selten, Michael Lynskey, Robin M Murray (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Prevalence of mental disorders in China – Author's reply
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Yueqin Huang (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

High-potency cannabis and incident psychosis: correcting the causal assumption
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Carey S Clark (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Research round-up
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Seema Kang (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Non-conforming, part 1: ICD-11
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Dustin M Graham (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Eiko Fried: organising incoherence with models, networks, and systems
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Jules Morgan (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

I remember, I remember: the therapeutic power of the medical memoir
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Linda Gask (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Endurance
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Alex Langford (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Living with a black hole
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Simon Guerrier (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

The PET and the pendulum: investigating hypnosis and the brain
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Peter Ranscombe (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Prevalence of mental disorders in China
Publication date: June 2019Source: The Lancet Psychiatry, Volume 6, Issue 6Author(s): Yu-Tao Xiang, Qinge Zhang, Gang Wang, Liang-Nan Zeng, Gabor S Ungvari (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 21, 2019 Category: Psychiatry Source Type: research

Correction to Lancet Psychiatry 2018; 5: 411–23
Publication date: Available online 17 May 2019Source: The Lancet PsychiatryAuthor(s): (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 18, 2019 Category: Psychiatry Source Type: research

Ethnic density and other neighbourhood associations for mortality in severe mental illness: a retrospective cohort study with multi-level analysis from an urbanised and ethnically diverse location in the UK
Publication date: Available online 13 May 2019Source: The Lancet PsychiatryAuthor(s): Jayati Das-Munshi, Peter Schofield, Vishal Bhavsar, Chin-Kuo Chang, Michael E Dewey, Craig Morgan, Robert Stewart, Graham Thornicroft, Martin J PrinceSummaryBackgroundNeighbourhood social context might play a role in modifying mortality outcomes in severe mental illness, but has received little attention to date. Therefore, we aimed to assess in an ethnically diverse and urban location the association of neighbourhood-level characteristics and individual-level factors for all-cause, natural-cause, and unnatural-cause mortality in those wi...
Source: The Lancet Psychiatry - May 15, 2019 Category: Psychiatry Source Type: research

Neighbourhood and mortality in severe mental illness
Publication date: Available online 13 May 2019Source: The Lancet PsychiatryAuthor(s): Ezra Susser, James B Kirkbride (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 15, 2019 Category: Psychiatry Source Type: research

Equity effects of parenting interventions for child conduct problems: a pan-European individual participant data meta-analysis
Publication date: Available online 6 May 2019Source: The Lancet PsychiatryAuthor(s): Frances Gardner, Patty Leijten, Victoria Harris, Joanna Mann, Judy Hutchings, Jennifer Beecham, Eva-Maria Bonin, Vashti Berry, Sinead McGilloway, Maria Gaspar, Maria João Seabra-Santos, Bram Orobio de Castro, Ankie Menting, Margiad Williams, Ulf Axberg, Willy-Tore Morch, Stephen Scott, Sabine LandauSummaryBackgroundChildhood conduct problems are a costly public health problem and are five times more common in socially disadvantaged groups than they are in advantaged groups. Untreated, conduct problems have a poor prognosis, with inc...
Source: The Lancet Psychiatry - May 8, 2019 Category: Psychiatry Source Type: research

Parenting groups can be effective across the social spectrum: the next step is access
Publication date: Available online 6 May 2019Source: The Lancet PsychiatryAuthor(s): Helen Minnis (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 8, 2019 Category: Psychiatry Source Type: research

Mapping genotype to phenotype in neurodevelopmental copy number variants
Publication date: Available online 2 May 2019Source: The Lancet PsychiatryAuthor(s): Varun Warrier, Simon Baron-Cohen (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 3, 2019 Category: Psychiatry Source Type: research

Considerations for clinicians treating Muslim patients with psychiatric disorders during Ramadan
Publication date: Available online 2 May 2019Source: The Lancet PsychiatryAuthor(s): Zainab Furqan, Rania Awaad, Paul Kurdyak, Muhammad I Husain, Nusrat Husain, Juveria Zaheer (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - May 3, 2019 Category: Psychiatry Source Type: research

Genotype–phenotype associations in children with copy number variants associated with high neuropsychiatric risk in the UK (IMAGINE-ID): a case-control cohort study
Publication date: Available online 2 May 2019Source: The Lancet PsychiatryAuthor(s): Samuel J R A Chawner, Michael J Owen, Peter Holmans, F Lucy Raymond, David Skuse, Jeremy Hall, Marianne B M van den BreeSummaryBackgroundSeveral copy number variants (CNVs) are associated with a high risk of neurodevelopmental and psychiatric disorders (referred to as ND-CNVs). We aimed to characterise the effect of ND-CNVs on childhood development and investigate whether different ND-CNVs lead to distinct and specific patterns of cognitive and behavioural outcomes.MethodsIn this case-control study, we used data from the Intellectual Disab...
Source: The Lancet Psychiatry - May 3, 2019 Category: Psychiatry Source Type: research

In-utero and perinatal influences on suicide risk: a systematic review and meta-analysis
This study was registered with PROSPERO, number CRD42018091205.FindingsWe identified 42 eligible studies; they had a low risk of bias (median quality score 9/9 [IQR 8–9]). Family or parental characteristics, such as high birth order (eg, for fourth-born or later-born vs first-born, pooled OR 1·51 [95% CIs 1·21–1·88]), teenage mothers (1·80 [1·52–2·14]), single mothers (1·57 [1·31–1·89]); indices of socioeconomic position, such as low maternal (1·36 [1·28–1·46]) and paternal (1·38 [1·27–1&mid...
Source: The Lancet Psychiatry - April 26, 2019 Category: Psychiatry Source Type: research

A few more questions for suicide prevention
Publication date: Available online 24 April 2019Source: The Lancet PsychiatryAuthor(s): Kees van Heeringen (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - April 26, 2019 Category: Psychiatry Source Type: research

Towards understanding atypical social affiliation in psychopathy
Publication date: May 2019Source: The Lancet Psychiatry, Volume 6, Issue 5Author(s): Essi Viding, Eamon McCrorySummaryOne distinctive feature of individuals with psychopathy is their reduced motivation and capacity to develop authentic social relationships, which are founded on an enjoyment of prosocial interactions or concern for others. Surprisingly, potential neurocognitive vulnerabilities contributing to atypical social affiliation, and lack of prosocial behaviours in psychopathy, have yet to be systematically investigated. Research efforts have largely focused on how individuals with psychopathy process negative emoti...
Source: The Lancet Psychiatry - April 21, 2019 Category: Psychiatry Source Type: research

A question of substance
Publication date: May 2019Source: The Lancet Psychiatry, Volume 6, Issue 5Author(s): The Lancet Psychiatry (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - April 21, 2019 Category: Psychiatry Source Type: research