Promoter polymorphisms in TGF ‐®1 and IL‐10 genes influence tumor dendritic cells infiltration, development and prognosis of colorectal cancer
ConclusionThe T‐allele of TGFB1 ‐509C/T SNP might be a protective factor for development of CRC, but in the course of the disease this variant allele might be associated with more unfavorable prognosis of the patients. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - January 1, 2018 Category: Genetics & Stem Cells Authors: Maya Gulubova, Elina Aleksandrova, Tatyana Vlaykova Tags: RESEARCH ARTICLE Source Type: research
MMP ‐3 (–1171 5A/6A; Lys45Glu) variants affect serum levels of matrix metalloproteinase (MMP)‐3 and correlate with severity of COPD: A study of MMP‐3, MMP‐7 and MMP‐12 in a Tunisian population
ConclusionsMMP‐3 (–1171) 5A/6A and Lys45Glu (A/G) polymorphisms were associated with the decline of lung function among COPD patients. These results could be linked to the upregulation of MMP‐3 in serum from COPD patients carrying the (–1171) 6A and 45 G homozygous genotypes. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 29, 2017 Category: Genetics & Stem Cells Authors: Sarra Bchir, Hela Nasr, Abdelhamid Garrouch, Amel Anes, Ammar Abbassi, Zouhair Tabka, Karim Chahed Tags: RESEARCH ARTICLE Source Type: research
Impact of cellular restriction gene (TRIM5 α, BST‐2) polymorphisms on the acquisition of HIV‐1 and disease progression
The Journal of Gene Medicine,Volume 20, Issue 2-3, February-March 2018. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 28, 2017 Category: Genetics & Stem Cells Source Type: research
Issue Information
No abstract is available for this article. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 20, 2017 Category: Genetics & Stem Cells Tags: ISSUE INFORMATION Source Type: research
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The Journal of Gene Medicine,Volume 20, Issue 1, January 2018. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 15, 2017 Category: Genetics & Stem Cells Source Type: research
Co ‐delivery of hypoxia inducible factor‐1α small interfering RNA and 5‐fluorouracil to overcome drug resistance in gastric cancer SGC‐7901 cells
ConclusionsCo‐delivery of siRNA and 5‐fluorouracil chitosan nanoparticles is an attractive strategy for overcoming multidrug resistance. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 11, 2017 Category: Genetics & Stem Cells Authors: Yunna Chen, Li Sun, Dongdong Guo, Ziteng Wu, Weidong Chen Tags: RESEARCH ARTICLE Source Type: research
Mesenchymal stem cell therapy: A promising cell ‐based therapy for treatment of myocardial infarction
Abstract
For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases as regenerative therapy. This review is an attempt to summarize the types of MSCs involved in myocardial infarction (MI) therapy, as well as its possible mechanisms effects, especially the paracrine one in MI focusing on the studies (human and animal) conducted within the last 10 years. Recently, reports showed that MSC therapy could have infarct‐limiting effects after MI in both experimental and clinical trials. In this context, various types of MSCs can help cardiac regeneration by either revitalizing the cardiac stem cells ...
Source: The Journal of Gene Medicine - December 8, 2017 Category: Genetics & Stem Cells Authors: Ayman El ‐Sayed Shafei, Mahmoud Ahmed Ali, Hazem G. Ghanem, Ahmed I. Shehata, Ahmed A. Abdelgawad, Hossam R. Handal, Kareem A. Talaat, Ahmed E. Ashaal, Amal S. El‐Shal Tags: REVIEW ARTICLE Source Type: research
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The Journal of Gene Medicine,Volume 20, Issue 1, January 2018. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 7, 2017 Category: Genetics & Stem Cells Source Type: research
Association of IGFN1 Variant with Polypoidal Choroidal Vasculopathy
ConclusionsOur findings indicate that although some of the susceptibility loci are shared between PCV and nAMD, a unique genetic signature may decide the pathogenesis of PCV. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 1, 2017 Category: Genetics & Stem Cells Authors: Xiaofeng Wen, Yu Liu, Qi Yan, Minling Liang, Miao Tang, Ran Liu, Jianying Pan, Qiuhui Liu, Tingting Chen, Shixin Guo, Juanran Liang, Lin Lu, Xiaoyan Ding, Wei Chen, Lai Wei Tags: RESEARCH ARTICLE Source Type: research
Impact of cellular restriction gene (TRIM5 α, BST‐2) polymorphisms on the acquisition of HIV‐1 and disease progression
ConclusionTRIM5α haplotypes and BST‐2 i19 allele may significantly affect the modulation of HIV‐1 acquisition and its progression. TRIM5α rs7127617 CC and BST‐2 Δ19/i19 genotypes in alcohol using HIV patients elevated the risk of HIV disease progression. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - December 1, 2017 Category: Genetics & Stem Cells Authors: HariOm Singh, Dharmesh Samani, Manisha V. Ghate, R.R. Gangakhedkar Tags: RESEARCH ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - November 28, 2017 Category: Genetics & Stem Cells Tags: ISSUE INFORMATION Source Type: research
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The Journal of Gene Medicine,Volume 20, Issue 1, January 2018. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - November 22, 2017 Category: Genetics & Stem Cells Source Type: research
IL ‐1RN gene polymorphisms are associated with breast cancer risk in a Chinese Han population
ConclusionsThe data obtained in the present study shed new light on the association between genetic polymorphisms of IL‐1RN and BC susceptibility in the Chinese Han population. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - November 9, 2017 Category: Genetics & Stem Cells Authors: Tianbo Jin, Wei Cao, Xiaoxiao Zuo, Miao Li, Ya Yang, Tiansong Liang, Hongyao Yang, Xinhan Zhao, Daoke Yang Tags: RESEARCH ARTICLE Source Type: research
Intra ‐articular Injection of Autologous Adipose Derived Mesenchymal Stem Cells in Treatment of Knee Osteoarthritis
ConclusionsOur results give a good basis for prospective randomized controlled clinical trials regarding the usage of AD‐MSCs in the treatment of osteoarthritis. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - November 1, 2017 Category: Genetics & Stem Cells Authors: Du ško Spasovski, Vesna Spasovski, Zoran Baščarević, Maja Stojiljković, Miša Vreća, Marina Andjelković, Sonja Pavlović Tags: RESEARCH ARTICLE Source Type: research
Association of PNPLA3 rs738409 polymorphism with Liver Steatosis but not with Cirrhosis in Patients with HBV Infection: Systematic Review with Meta ‐analysis
ConclusionsAlthough the PNPLA3 rs738409 G allele has been associated with the risk of steatosis in CHB patients, no association between this polymorphism and the risk of cirrhosis was seen. (Source: The Journal of Gene Medicine)
Source: The Journal of Gene Medicine - November 1, 2017 Category: Genetics & Stem Cells Authors: Saman Ghalamkari, Heidar Sharafi, Seyed Moayed Alavian Tags: REVIEW ARTICLE Source Type: research
