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Trauma in childhood associated with risk to female offspring
Can childhood trauma be inherited or passed on in some way? The answer is yes, but exactly how is unclear. Adverse childhood experiences (ACEs) are not only associated with scarring in adulthood, but there is evidence that the harms could be passed down to the next generation as well. In one study looking specifically at psychiatric hospitalization, researchers have found that the risk was passed down from mothers, but not fathers, and passed down only to females, not males. The highest risk in offspring was for mood disorders. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - December 26, 2017 Category: Psychiatry Tags: ACEs Source Type: research

Buprenorphine and Vivitrol perform equally well in head ‐to‐head study
The first head‐to‐head study comparing buprenorphine‐naloxone with extended‐release naltrexone in the United States has found both medications are equally successful at retaining patients 6 months later. The study, published online Nov. 14 in The Lancet, was led by senior author John Rotrosen, M.D., and colleagues at the NYU School of Medicine, and conducted in eight sites throughout the United States. The study was funded by the National Institute on Drug Abuse (NIDA). (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 28, 2017 Category: Psychiatry Tags: Substance use disorders Source Type: research

FDA approves Abilify pill with sensor that tracks compliance
The U.S. Food and Drug Administration last month approved the first drug in the United States with a digital ingestion tracking system. Abilify MyCite (aripiprazole tablets with sensor) has an ingestible sensor embedded in the pill that records that the medication was taken. The product is approved for the treatment of schizophrenia, for acute treatment of manic and mixed episodes associated with bipolar I disorder, and for use as an add‐on treatment for depression in adults. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 28, 2017 Category: Psychiatry Tags: From the FDA Source Type: research

Approach to drug crisis shifts as illicit fentanyl and heroin overtake prescription opioids
There's an innovation of sorts going on in the federal approach to opioid overdoses; a year ago, the federal Centers for Disease Control and Prevention (CDC) was saying that the best way to deal with the problem was to reduce access to prescription opioids. At the same time, the CDC also denied that these cutbacks were not driving people to illicit opioids. In the wake of several reports, however, the tone has changed. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 28, 2017 Category: Psychiatry Tags: What's New in Research Source Type: research

Novel approaches for preventing substance use
Researchers at the AMERSA (Association for Medical Education and Research in Substance Abuse) meeting in early November talked about prevention among youth, highlighting some innovative approaches. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 28, 2017 Category: Psychiatry Tags: What's New in Research Source Type: research

Metformin can treat antipsychotic ‐induced overweight in young people with autism
It is known that atypical antipsychotics cause weight gain and metabolic problems; however, metformin can result in reduction in body mass index (BMI) and weight when prescribed to children and adolescents with autism spectrum disorder (ASD) who are prescribed atypical antipsychotics for irritability and aggression; those improvements level off at 16 weeks, a new study has found. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 28, 2017 Category: Psychiatry Tags: Autism spectrum disorders Source Type: research

Review: CBT and SSRIs/SNRIs effective for childhood anxiety disorders, but more comparison studies needed
When treating anxiety, clinicians have options between multiple treatments. Specifically, cognitive behavioral therapy (CBT) and pharmacotherapy exist for childhood anxiety disorders. Researchers conducted a literature search to compare the effectiveness of the two treatments. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: Anxiety Source Type: research

Codeine and tramadol can cause breathing problems for children
Codeine and tramadol are opioid medicines that may be used to treat pain. Codeine is also in some cough and cold remedies. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: From the FDA Source Type: research

Research Roundup
Baclofen found ineffective in AUD RCT Doctors fear loss of medical license if they seek mental health care UCLA embarking on depression study with incoming freshmen (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: Research Roundup Source Type: research

Heroin tops list of first opioid of use
For the first time, data shows that heroin and not a prescription opioid has become the most common opioid of initial use, suggesting that addiction treatment programs likely will be seeing a younger, sicker patient base — if these individuals ever make it to treatment at all. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: What's New in Research Source Type: research

Aftereffects of bullying can decline over time
Although children exposed to bullying experience symptoms of depression and anxiety, these effects dissipated over time, highlighting the potential for resilience in children who are bullied, along with the need for interventions that address pre‐existing vulnerabilities, according to researchers of a new study published online Oct. 4 in JAMA Psychiatry. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: What's New in Research Source Type: research

Civil commitment for SUDs: One answer for families?
This summer, the Hazelden Betty Ford Foundation released a research paper embracing the concept of civil commitment for substance use disorders (SUDs). The driving force is similar to that for suicidality: saving the life of a possible overdose victim. In issuing this paper, called “Involuntary Commitment for Substance Use Disorders,” Hazelden Betty Ford has opened a national dialogue among treatment providers on this controversial issue. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - October 27, 2017 Category: Psychiatry Tags: Substance Use Disorders Source Type: research

Pharmacologic algorithm helps clinicians treat children at risk for bipolar disorder
Depression with brief manic periods can presage bipolar disorder in children who have a parent or sibling with the disorder. However, there is no evidence for medications for these children, so researchers proposed a pharmacologic algorithm for high‐risk youth. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - September 25, 2017 Category: Psychiatry Tags: Bipolar Disorder Source Type: research

FDA permits marketing of mobile medical application for substance use disorder
Last month, the U.S. Food and Drug Administration permitted marketing of the first mobile medical application to help treat substance use disorder (SUD). The Reset application is intended to be used with outpatient therapy to treat alcohol, cocaine, marijuana, and stimulant SUDs. The application is not intended to be used to treat opioid dependence. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - September 25, 2017 Category: Psychiatry Tags: From the FDA Source Type: research

Experts: CDC stats on suicide rates for teen girls alarming, action needed
While experts cannot say what specific factors have contributed to the increased suicide rates among teen girls, hitting an all‐time high in 2015, according to the Centers for Disease Control & Prevention (CDC), the statistics are alarming and more action is needed toward efforts in preventing suicide in children, teens, and young adults, they said. (Source: The Brown University Child and Adolescent Psychopharmacology Update)
Source: The Brown University Child and Adolescent Psychopharmacology Update - September 25, 2017 Category: Psychiatry Tags: News Source Type: research