Acupuncture for Acute Stroke [Cochrane Corner]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mangmang Xu, Dan Li, Shihong Zhang Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Cochrane Corner Source Type: research

Factor Xa Inhibitors Versus Vitamin K Antagonists for Prevention of Cerebral or Systemic Embolism in Patients With Atrial Fibrillation [Cochrane Corner]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Karsten M.H. Bruins Slot, Eivind Berge Tags: Atrial Fibrillation, Anticoagulants, Cerebrovascular Disease/Stroke Cochrane Corner Source Type: research

Role of Autophagy in Endothelial Damage and Blood-Brain Barrier Disruption in Ischemic Stroke [Basic Science Advances for Clinicians]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Kyeong-A Kim, Donggeun Shin, Jeong-Hyeon Kim, Young-Jun Shin, G.K. Rajanikant, Arshad Majid, Seung-Hoon Baek, Ok-Nam Bae Tags: Endothelium/Vascular Type/Nitric Oxide, Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Basic Science Advances for Clinicians Source Type: research

Stem Cell-Based Immunomodulation After Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Marieke C.S. Boshuizen, Gary K. Steinberg Tags: Inflammation, Stem Cells, Ischemic Stroke Topical Reviews Source Type: research

Imaging Endophenotypes of Stroke as a Target for Genetic Studies [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Xueqiu Jian, Myriam Fornage Tags: Genetic, Association Studies, Genetics, Cerebrovascular Disease/Stroke, Ischemic Stroke Topical Reviews Source Type: research

Patient-Reported Outcome Measures (PROMs) for Acute Stroke: Rationale, Methods and Future Directions [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Mathew Reeves, Lynda Lisabeth, Linda Williams, Irene Katzan, Moira Kapral, Anne Deutsch, Janet Prvu-Bettger Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke Topical Reviews Source Type: research

Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Jeffrey L. Saver, Heinrich P. Mattle, David Thaler Tags: Congenital Heart Disease, Treatment, Ischemic Stroke Topical Reviews Source Type: research

In the Era of Thrombectomy, Let Us Also Protect the Majority of Patients With Stroke Who Only Require Medical Treatment! [Comments and Opinions]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Enrique C. Leira, Sean I. Savitz Tags: Ethics and Policy, Health Services, Ischemic Stroke Comments and Opinions Source Type: research

Different Effects of Normobaric Oxygen in Normotensive Versus Hypertensive Rats After Focal Cerebral Ischemia [Brief Report]
Conclusions—NBO reduced infarction in Sprague–Dawley but not in spontaneously hypertensive rats. These findings suggest that comorbidities may influence responses to potential treatments after stroke. (Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Jing Lan, Elga Esposito, Cenk Ayata, Aneesh B. Singhal, Eng H. Lo, Xunming Ji Tags: Ischemic Stroke Brief Reports Source Type: research

Effect of Antihypertensive Medication on Cerebral Small Vessel Disease [Brief Report]
Conclusions—AHM has a protective effect on the progression of white matter hyperintensities, but no effect on brain atrophy. There are no trials on the effect of AHM on lacunes, microbleeds, enlarged perivascular spaces, or acute small subcortical infarcts. (Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Tessa van Middelaar, Tanja E. Argillander, Floris H.B.M. Schreuder, Jaap Deinum, Edo Richard, Catharina J.M. Klijn Tags: Primary Prevention, Hypertension, Magnetic Resonance Imaging (MRI), Meta Analysis, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Time to Decision and Treatment With tPA (Tissue-Type Plasminogen Activator) Using Telemedicine Versus an Onboard Neurologist on a Mobile Stroke Unit [Brief Report]
Conclusions—Assessment by a TM-VN is comparable with an OB-VN in making decisions about tPA administration on an MSU and does not lead to treatment delays.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02190500. (Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Ritvij Bowry, Stephanie A. Parker, Jose-Miguel Yamal, Hyunsoo Hwang, Savitri Appana, Nicole Rangel-Gutierrez, Tzu-Ching Wu, Suja S. Rajan, James C. Grotta Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Low Levels of Caveolin-1 Predict Symptomatic Bleeding After Thrombolytic Therapy in Patients With Acute Ischemic Stroke [Brief Report]
Background and Purpose—Experimental models of cerebral ischemia demonstrate that the decrease in the caveolin-1 membrane protein results in an increase in endothelial permeability. Because this phenomenon is responsible for hemorrhagic transformation (HT) after cerebral ischemia, we aimed to determine whether caveolin-1 levels may predict bleeding after recombinant tissue-type plasminogen activator (r-tPA) administration in patients with acute stroke.Methods—We studied 133 patients with a first hemispheric stroke treated with r-tPA within 4.5 hours of symptom onset. HT was evaluated and classified on cranial computed t...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Mar Castellanos, Cecile van Eendenburg, Carme Gubern, Elisabet Kadar, Gemma Huguet, Josep Puig, Tomas Sobrino, Gerard Blasco, Joaquin Serena, Juan Manuel Sanchez Tags: Biomarkers, Endothelium/Vascular Type/Nitric Oxide, Blood-Brain Barrier, Ischemic Stroke Brief Reports Source Type: research

Shorter Intensive Care Unit Stays? [Brief Report]
Conclusions—sICH associated with the administration of intravenous tPA typically occurs within the first 12 hours of treatment. Longer monitoring in an intensive care unit-like setting may be unnecessary for most individuals. (Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Adam Chang, Edward J. Llinas, Karen Chen, Rafael H. Llinas, Elisabeth B. Marsh Tags: Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Innovative Magnetic Resonance Imaging Markers of Hereditary Cerebral Amyloid Angiopathy at 7 Tesla [Brief Report]
Background and Purpose—The aim of the present study is to explore whether using 7 Tesla magnetic resonance imaging, additional brain changes can be observed in hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D) patients as compared with the established magnetic resonance imaging features of sporadic cerebral amyloid angiopathy.Methods—The local institutional review board approved this prospective cohort study. In all cases, informed consent was obtained. This prospective parallel cohort study was conducted between 2012 and 2014. We performed T2*-weighted magnetic resonance imaging performed at 7 Tesla...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Emma A. Koemans, Ellis S. van Etten, Anna M. van Opstal, Gerda Labadie, Gisela M. Terwindt, Marieke J.H. Wermer, Andrew G. Webb, Edip M. Gurol, Steven M. Greenberg, Mark A. van Buchem, Jeroen van der Grond, Sanneke van Rooden Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Vascular Disease Brief Reports Source Type: research

Distribution of Lacunar Infarcts in Asians With Intracerebral Hemorrhage [Brief Report]
Conclusions—Our findings expand on recent work showing that lobar lacunes are more frequent in CAA-ICH than hypertensive ICH. Their independent association with lobar cerebral microbleeds and brain amyloid deposition suggests a relationship with CAA even in an Asian cohort with overall higher hypertensive load. (Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Hsin-Hsi Tsai, Marco Pasi, Li-Kai Tsai, Ya-Fang Chen, Bo-Ching Lee, Sung-Chun Tang, Panagiotis Fotiadis, Chen-Yu Huang, Ruoh-Fang Yen, M. Edip Gurol, Jiann-Shing Jeng Tags: Intracranial Hemorrhage Brief Reports Source Type: research