Using actigraphy to assess sleep and wake rhythms of narcolepsy type 1 patients: a comparison with primary insomniacs and healthy controls
It has been shown that actigraphy may have discriminant function (DS) for the diagnosis for narcoleptic type 1 patients (NT1) based on the combination of nighttime and daytime parameters. Here, we aimed to test those findings using another actigraph model with a different clinical sample as control (i.e., primary insomniacs, PI), carrying out a secondary analysis of previously collected data. (Source: Sleep Medicine)
Source: Sleep Medicine - August 31, 2018 Category: Sleep Medicine Authors: Damien Leger, Caroline Gauriau, Lorenzo Tonetti, Michaele Lantin, Marco Filardi, Pierre Philip, Brice Faraut, Vincenzo Natale Source Type: research

Benzodiazepines and Z-drugs may cause prolonged cognitive issues in young adults – are hypnotics not only a geriatric dilemma?
The risks of benzodiazepines (BZDs) in the elderly are well known. BZD use has been associated with increased risks of fallings, fractures, disabilities of mobility, deteriorated activities of daily living, traffic accidents, chemical restraining and mortality [1-6]. Moreover, acute psychocognitive and motor complications related to BZDs have been shown in short-term, randomized, controlled trials [7]. In addition, the newer ‘Z-drugs’ such as zopiclone, zolpidem or zolpidem have not been shown to be better than conventional BZDs [8]. (Source: Sleep Medicine)
Source: Sleep Medicine - August 31, 2018 Category: Sleep Medicine Authors: Juha Puustinen Source Type: research

Effects of Zero-time Exercise on inactive adults with insomnia disorder: A pilot randomized controlled trial
To evaluate the feasibility and clinical effects of a lifestyle-integrated exercise, namely zero-time exercise (ZTEx), on improving insomnia in inactive adults with insomnia disorder. (Source: Sleep Medicine)
Source: Sleep Medicine - August 24, 2018 Category: Sleep Medicine Authors: Wing-Fai Yeung, Agnes Yuen-Kwan Lai, Fiona Yan-Yee Ho, Lorna Kwai-Ping Suen, Ka-Fai Chung, Janice Yuen-Shan Ho, Lai-Ming Ho, Branda Yee-Man Yu, Lily Ying-Tung Chan, Tai-Hing Lam Tags: Original Article Source Type: research

A narrative review of interventions for improving sleep and reducing circadian disruption in medical inpatients
Sleep and circadian rhythm disruption are frequently observed in patients across hospital departments. This is alarming since impaired nocturnal sleep and disruption to a normal circadian rhythm can compromise health and disturb processes involved in recovery from illness (eg, immune functions). With this in mind, the present narrative review discusses how patient characteristics (sleep disorders, anxiety and stress, chronotype and disease), hospital routines (pain management, timing of medication, nocturnal vital sign monitoring and physical inactivity), and hospital environment (light, noise) may all contribute to sleep ...
Source: Sleep Medicine - August 23, 2018 Category: Sleep Medicine Authors: Xiao Tan, Lieve van Egmond, Markku Partinen, Tanja Lange, Christian Benedict Tags: Review Article Source Type: research

Association between sleep duration during pregnancy and gestational diabetes mellitus: a meta-analysis
Sleep is critical for glucose metabolism. Pregnant women often have sleep disturbances and extreme sleep duration. Investigations of the relationship between sleep duration during pregnancy and gestational diabetes mellitus (GDM) have reported inconsistent results. The present study aimed to meta-analyze the relationship between sleep duration during pregnancy and GDM risk. (Source: Sleep Medicine)
Source: Sleep Medicine - August 22, 2018 Category: Sleep Medicine Authors: Ya-hui Xu, Le Shi, Yan-Ping Bao, Si-Jing Chen, Jie Shi, Rui-Ling Zhang, Lin Lu Source Type: research

The association between multiple sleep-related characteristics and the metabolic syndrome in the general population: The New Hoorn study
Previous studies have investigated the association between sleep duration, insomnia, day-time napping and the metabolic syndrome individually, but never in combination; the association with sleep medication use has yet to be investigated. We aimed to examine the associations between these sleep-related characteristics and the metabolic syndrome, individually and conjointly, in a population-based cohort. (Source: Sleep Medicine)
Source: Sleep Medicine - August 22, 2018 Category: Sleep Medicine Authors: Kaira C. van der Pal, Anitra DM. Koopman, Jeroen Lakerveld, Amber A. van der Heijden, Petra J. Elders, Joline W. Beulens, Femke Rutters Source Type: research

Polysomnographic Correlates of Endothelial Function in Children with Obstructive Sleep Apnea
To evaluate endothelial function in a large cohort of children clinically referred for suspected obstructive sleep apnea syndrome (OSAS), and to identify risk factors contributing to the presence of endothelial dysfunction (ED). (Source: Sleep Medicine)
Source: Sleep Medicine - August 22, 2018 Category: Sleep Medicine Authors: Fengjie Zhang, Yunxiao Wu, Guoshuang Feng, Xin Ni, Zhifei Xu, David Gozal Tags: Original Article Source Type: research

Early Nighttime Parental Interventions and Infant Sleep Regulation Across the First Year
This study used observational and survey data to investigate how sleeping arrangement and two types of nighttime interventions at one and three months (non-distress-initiated and distress-initiated) are associated with infants ’ sleep development across the first 9 months. Distress-initiated interventions were identified as parents’ responses to infants’ distress signals whereas non-distress initiated interventions were identified as parents’ behaviors in response to non-distressed vocalizations or while infants w ere asleep. (Source: Sleep Medicine)
Source: Sleep Medicine - August 20, 2018 Category: Sleep Medicine Authors: Sabrina T. Voltaire, Douglas M. Teti Tags: Original Article Source Type: research

Last Night ’s Sleep in Relation to Academic Achievement and Neurocognitive Testing Performance in Adolescents with and without ADHD
Objectives were to (1) examine previous night ’s sleep in relation to next day performance on standardized academic achievement and neurocognitive assessments in adolescents, and (2) explore whether previous night’s sleep is differentially associated with testing performance for adolescents with and without attention-deficit/hyperactivity d isorder (ADHD). (Source: Sleep Medicine)
Source: Sleep Medicine - August 20, 2018 Category: Sleep Medicine Authors: Caroline N. Cusick, Paul A. Isaacson, Joshua M. Langberg, Stephen P. Becker Tags: Brief Communication Source Type: research

Sharpening the contours of positional OSA
Editorial accompanying the original paper ‘A systematic comparison of factors that could impact recommendations for patients with Positional Obstructive Sleep Apnea (POSA)’. (Source: Sleep Medicine)
Source: Sleep Medicine - August 17, 2018 Category: Sleep Medicine Authors: M. Sastry, D. Pevernagie Tags: Editorial Source Type: research

Music therapy in a sleepless child with Pierre Robin sequence, partial trisomy 14 and partial monosomy 21
Originally described in 1923 by Pierre Robin, Pierre Robin sequence (PRS) is a condition characterized by a triad consisting of micrognathia, glossoptosis and breathing problems due to obstruction of the upper airway [1]. The prevalence of PRS is highly variable and reported to be between 1 in 2000 to 1 in 30,000 [2]. PRS can be found as isolated disease or in association with other syndromes such as Stickler sundrome, Fetal Alcohol Syndrome and Monosomy 22q11 or DiGeorge Syndrome [3]. Although the strong concurrence of Obstructive Sleep Apnea and PRS has been known, no previous study has reported other sleep problems and ...
Source: Sleep Medicine - August 17, 2018 Category: Sleep Medicine Authors: Duygu Duran Orlowski, Levent Öztürk Tags: Letter to the Editor Source Type: research

Assessment of Change in Restless Legs Syndrome Symptoms during the Acute Drug-withdrawal Period
The standard treatment of restless legs syndrome (RLS) with dopaminergic (DA) agents is complicated by the eventual development of augmentation and the need for alternative therapy [1-6]. Part of the treatment for subjects augmented on DA agents is to taper down and off of the DA agent [6]. Clinical reports during the first several days off the DA agents indicate patients may experience severe sleep loss with worsening of RLS symptoms. This experience may result in the failure to get off the medication [7]. (Source: Sleep Medicine)
Source: Sleep Medicine - August 17, 2018 Category: Sleep Medicine Authors: Allan Wang, Keyana Foster, Patrick Skeba, Kasidet Hiranniramol, Christopher J. Earley, Richard P. Allen Tags: Original Article Source Type: research

Chronotype, Social Jet Lag, Sleep Debt and Food Timing in Inflammatory Bowel Disease
The preference of the sleep/wake cycle can be grouped into categories or chronotypes. Inflammatory bowel disease (IBD) has been linked to poor sleep quality which correlates with disease severity. Social jet lag (SJL) is the difference between sleep timing on work and free days and is a marker for circadian misalignment which has been linked to increased inflammation. We investigated whether chronotype, SJL, sleep debt, and food timing were associated with an IBD specific complications and a lower quality of life. (Source: Sleep Medicine)
Source: Sleep Medicine - August 16, 2018 Category: Sleep Medicine Authors: Prachi S. Chakradeo, Ali Keshavarzian, Shubha Singh, Akram E. Dera, James Philip G. Esteban, Alice A. Lee, Helen J. Burgess, Louis Fogg, Garth R. Swanson Tags: Original Article Source Type: research

Alpha-synuclein aggregates in the parotid gland of idiopathic REM sleep behavior disorder
We report a patient with video-polysomnography-confirmed idiopathic REM sleep behavior disorder that underwent parotidectomy because of parotid gland cancer. Immunohistochemistry of the gla nd tissue revealed abundant pAS deposits. One year after surgery the patient was diagnosed with PD. Prompted by this observation we examined the parotid gland in 10 consecutive individuals that underwent elective parotidectomy irrespective of their clinical condition. (Source: Sleep Medicine)
Source: Sleep Medicine - August 13, 2018 Category: Sleep Medicine Authors: Ana Fern ández-Arcos, Isabel Vilaseca, Iban Aldecoa, Mónica Serradell, Eduard Tolosa, Joan Santamaría, Ellen Gelpi, Alex Iranzo Tags: Brief Communication Source Type: research

Sleep, pain, and the problem with treating sleep to relieve pain
Sleep and pain are reliably linked. Numerous reviews and meta-analyses have reached this conclusion [1 –5], and work on this subject has accelerated in recent years. A very basic Google Scholar search of articles including the terms “sleep” and “pain” yields 866,000 results over the past decade compared to 386,000 results over the prior decade. As research methods have become more intricate and interest in the association of sleep and pain has burgeoned, clear directional relations between sleep and pain have emerged, suggesting that treating sleep might improve chronic pain. (Source: Sleep Medicine)
Source: Sleep Medicine - August 10, 2018 Category: Sleep Medicine Authors: Patrick H. Finan Tags: Editorial Source Type: research