Extracorporeal membrane oxygenation (ECMO) during pregnancy and postpartum
Extracorporeal membrane oxygenation (ECMO) can provide respiratory support (VV-ECMO) or both respiratory and circulatory support (VA-ECMO). The use of ECMO has increased dramatically as a result of simpler technology. No level I evidence is yet available reflecting improved outcomes with ECMO. The use of this technology during pregnancy may be indicated in very select cases and should be delivered in centers with dedicated ECMO specialized units. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - November 24, 2017 Category: Perinatology & Neonatology Authors: Luis D. Pacheco, George R. Saade, Gary D.V. Hankins Source Type: research

Catastrophic antiphospholipid syndrome and pregnancy
Catastrophic antiphospholipid syndrome (CAPS) is a rare but life-threatening condition that may be precipitated by pregnancy. The condition can be hard to diagnose since it mimics other thrombotic microangiopathies that are associated with pregnancy. Accurate and timely diagnosis is critical for effective treatment. In this review, we highlight pertinent clinical features of CAPS so that obstetricians will be able to recognize and treat the condition. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - November 24, 2017 Category: Perinatology & Neonatology Authors: Robert M. Silver Source Type: research

The utility of bedside simulation for training in critical care obstetrics
Over the last 2 decades, the maternal mortality ratio in the United States has doubled from 7.4/100,000 live births in 1986 to 14.5/100,000 today. Despite great advances in health care, increasing rates of maternal morbidity and mortality in the United States have prompted calls to action to reverse this disturbing trend. Assisted reproductive technology has allowed women to delay childbearing to more advanced ages, resulting in a greater number of pregnancies complicated by one or more of the diseases associated with aging, such as cardiovascular disease, cancer, type 2 diabetes, and hypertension. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - November 24, 2017 Category: Perinatology & Neonatology Authors: Jean-Ju Sheen, Colleen Lee, Dena Goffman Source Type: research

Novel thoughts on preterm birth research proceedings of the 13th annual preterm birth international collaborative (PREBIC) meeting
In 1961, the World Health Organization (WHO) defined preterm birth (PTB) as birth before 37 completed weeks of gestation.1 Since which time, the rate of PTB has not decreased, albeit that the risk factors for PTB such as obesity, substance abuse and multiple pregnancy have increased. Thirty-seven weeks gestation was chosen because at this gestational age, 2500g represents the 10th centile for birth weight, and provides the definition of low birth weight (LBW). However, while 60% of PTBs occur after 35 completed weeks of gestation, about 90% of the associated morbidity and mortality occurs before this time. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 24, 2017 Category: Perinatology & Neonatology Authors: Cynthia Gyamfi-Bannerman, Ramkumar Menon, Elizabeth A. Bonney, Siobhan M. Dolan, Mark Johnson, Ronald F. Lamont, Sam Mesiano, Amy P. Murtha, Leslie Myatt, Indira Mysorekar, Scott M Williams, Nanbert Zhong, Hanns Helmer Source Type: research

Cover (pms 486 k)
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 24, 2017 Category: Perinatology & Neonatology Source Type: research

Masthead
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 24, 2017 Category: Perinatology & Neonatology Source Type: research

Topics
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 24, 2017 Category: Perinatology & Neonatology Source Type: research

Table of contents
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 24, 2017 Category: Perinatology & Neonatology Source Type: research

Current options for mechanical prevention of preterm birth
Cervical insufficiency can be defined by a combination of obstetric history, cervical dilation on exam, and/or short cervical length in women with prior preterm birth. Options for mechanical intervention include cerclage and pessary. There is evidence to support the benefit of a cervical cerclage in women with singleton gestations who have a diagnosis of cervical insufficiency either based on second trimester painless cervical dilatation leading to recurrent early preterm births, or a history of early spontaneous preterm birth and a second trimester transvaginal ultrasound short cervical length or cervical dilation on exam...
Source: Seminars in Perinatology - October 21, 2017 Category: Perinatology & Neonatology Authors: Rupsa C. Boelig, Vincenzo Berghella Source Type: research

Prevention of preterm birth: Novel interventions for the cervix
Preterm birth is the leading cause of neonatal mortality and morbidity worldwide. Spontaneous preterm birth is a complex, multifactorial condition in which cervical dysfunction plays an important role in some women. Current treatment options for cervical dysfunction include cerclage and supplemental progesterone. In addition, cervical pessary is being studied in research protocols. However, cerclage, supplemental progesterone and cervical pessary have well known limitations and there is a strong need for alternate treatment options. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 6, 2017 Category: Perinatology & Neonatology Authors: Bouchra Koullali, Andrea R. Westervelt, Kristin M. Myers, Michael D. House Tags: Regular Articles Source Type: research

The prevalence of selected major birth defects in the United States
This article provides an overview of the prevalence, trends and selected socio-demographic risk factors for several major birth defects, including neural tube defects, cranio-facial anomalies, congenital heart defects, trisomies 13, 18, and 21, and gastroschisis and omphalocele. Attention should focus on strengthening existing registries, creating birth defects surveillance programs in states that do not have them, and standardizing registry methods so that broadly national data to monitor these trends are available. (Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 1, 2017 Category: Perinatology & Neonatology Authors: Russell S. Kirby Source Type: research

Cover (pms 486 k)
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 1, 2017 Category: Perinatology & Neonatology Source Type: research

Masthead
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 1, 2017 Category: Perinatology & Neonatology Source Type: research

Topics
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 1, 2017 Category: Perinatology & Neonatology Source Type: research

Table of contents
(Source: Seminars in Perinatology)
Source: Seminars in Perinatology - October 1, 2017 Category: Perinatology & Neonatology Source Type: research