Subcortical neural tracks play an important role in executive function in schizophrenia: An experimental study among patients with schizophrenia and healthy comparisons
Publication date: December 2020Source: Schizophrenia Research: Cognition, Volume 22Author(s): Noa Peskin, Dan Koren, Shai Gabay (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 23, 2020 Category: Psychiatry Source Type: research

The effect of bilateral high frequency repetitive transcranial magnetic stimulation on cognitive functions in schizophrenia
Publication date: December 2020Source: Schizophrenia Research: Cognition, Volume 22Author(s): Mehmet Diyaddin Güleken, Taner Akbaş, Selime Çelik Erden, Veysel Akansel, Zeliha Cengiz Al, Ömer Akil Özer (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 18, 2020 Category: Psychiatry Source Type: research

Correlations between age, biomedical variables, and cognition in patients with schizophrenia
Publication date: December 2020Source: Schizophrenia Research: Cognition, Volume 22Author(s): Wei Tang, Kai-li Fan, Shu-zhen Zhao, Yao-yao Zhang, Yan Li, Sheng-min Shao, Zheng Wang, Jiang-qiong Ke (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - June 17, 2020 Category: Psychiatry Source Type: research

Evaluation of executive functions and everyday life for people with severe mental illness: A systematic review
Publication date: September 2020Source: Schizophrenia Research: Cognition, Volume 21Author(s): Sivan Regev, Naomi Josman (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 25, 2020 Category: Psychiatry Source Type: research

Gaze direction biases emotion categorisation in schizophrenia
Publication date: September 2020Source: Schizophrenia Research: Cognition, Volume 21Author(s): Nathan Caruana, Christine Inkley, Marwa El Zein (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 22, 2020 Category: Psychiatry Source Type: research

Does childhood trauma influence cognitive functioning in schizophrenia? The association of childhood trauma and cognition in schizophrenia spectrum disorders.
Publication date: September 2020Source: Schizophrenia Research: Cognition, Volume 21Author(s): N. Mørkved, E. Johnsen, R.A. Kroken, R. Gjestad, D. Winje, J. Thimm, F. Fathian, M. Rettenbacher, L.G. Anda, E.M. Løberg (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 20, 2020 Category: Psychiatry Source Type: research

A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine
Publication date: September 2020Source: Schizophrenia Research: Cognition, Volume 21Author(s): Katherine E. Burdick, Mercedes Perez-Rodriguez, Rebecca Birnbaum, Megan Shanahan, Emmett Larsen, Cierra Harper, Jessica Poskus, Pamela Sklar (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 19, 2020 Category: Psychiatry Source Type: research

Verbal memory measurement towards digital perspectives in first-episode psychosis: A review
Publication date: September 2020Source: Schizophrenia Research: Cognition, Volume 21Author(s): Can Mişel Kilciksiz, Richard Keefe, James Benoit, Dost Öngür, John Torous (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 16, 2020 Category: Psychiatry Source Type: research

Risk perception in paranoia and anxiety: Two investigations across clinical and non-clinical populations
Publication date: Available online 29 March 2020Source: Schizophrenia Research: CognitionAuthor(s): Suzanne Ho-wai So, Xiaoqi Sun, Gloria Hoi Kei Chan, Iris Hiu Hung Chan, Chui De Chiu, Sherry Kit Wa Chan, Wai Yin Elisabeth Wong, Patrick Wing-leung Leung, Eric Yu Hai Chen (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 31, 2020 Category: Psychiatry Source Type: research

False memory production in schizophrenia: A neurophysiological investigation
Publication date: June 2020Source: Schizophrenia Research: Cognition, Volume 20Author(s): Grégoire Favre, Sibylle K. Horat, François R. Herrmann, Isabelle Gothuey, Joseph Ventura, Marco C.G. Merlo, Pascal Missonnier (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 3, 2020 Category: Psychiatry Source Type: research

Cognitive functioning in adolescents with schizophrenia treated with paliperidone extended-release: 6-Month exploratory analysis from an open-label, single-arm safety study
Publication date: June 2020Source: Schizophrenia Research: Cognition, Volume 20Author(s): Gahan Pandina, Isaac Nuamah, Timothy Petersen, Jaskaran Singh, Adam Savitz, David Hough (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 3, 2020 Category: Psychiatry Source Type: research

Neurocognitive variability in schizophrenia spectrum disorders: relationship to real-world functioning
Publication date: June 2020Source: Schizophrenia Research: Cognition, Volume 20Author(s): Lars Helldin, Christine Mohn, Anna-Karin Olsson, Fredrik HjärthagAbstractNeurocognitive variability exists within the schizophrenia spectrum disorder (SSD) population, with subgroups performing at the same level as healthy samples Here we study the relationship between different levels of neurocognitive responding and real-world functioning. The participants were 291 SSD patients and 302 healthy controls that were assessed with a comprehensive neurocognitive battery. In addition, the patients were assessed with the Specific Level...
Source: Schizophrenia Research: Cognition - February 15, 2020 Category: Psychiatry Source Type: research

Six month durability of targeted cognitive training supplemented with social cognition exercises in schizophrenia
ConclusionsBoth TCT + SCT and TCT-only result in durable improvements in cognition, symptoms, and functional capacity six months post-intervention. Supplementing TCT with social cognitive training offers greater and enduring benefits in prosody identification and reward processing. These results suggest that novel cognitive training approaches that integrate social cognitive exercises may lead to greater improvements in reward processing and functioning in individuals with schizophrenia. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - December 28, 2019 Category: Psychiatry Source Type: research

Susceptibility to distraction during analogical reasoning in schizophrenia
Publication date: Available online 11 December 2019Source: Schizophrenia Research: CognitionAuthor(s): Hanna Kucwaj, Adam ChuderskiAbstractProportional analogies between four objects (e.g., a squirrel is to tree as a golden fish is to? aquarium) were examined in 30 schizophrenia patients and 30 healthy controls. Half of the problems included distracting response options: remote semantic associates (fishing rod) and perceptually similar salient distractors (shark). Although both patients and controls performed fairly accurately on the no-distraction analogies, patients’ performance in the presence of distractors was d...
Source: Schizophrenia Research: Cognition - December 13, 2019 Category: Psychiatry Source Type: research

Evaluation of social cognitive measures in an Asian schizophrenia sample
ConclusionHere, we examined the psychometric properties of a comprehensive social cognition battery based on the SCOPE study in an Asian schizophrenia population. Continued evaluation and standardization of social cognitive measures are needed to refine our understanding of this construct in schizophrenia. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - December 11, 2019 Category: Psychiatry Source Type: research

Schizophrenia, recovery and the self: An introduction to the special issue on metacognition
Publication date: Available online 4 November 2019Source: Schizophrenia Research: CognitionAuthor(s): Paul H. Lysaker, Jennifer E. Keane, Sara Poirier Culleton, Nancy B. LundinAbstractIn this special issue, work is presented linking metacognition among persons with schizophrenia with a range of psychosocial outcomes including vocational functioning, empathy, motivation, self-evaluation, and other cognitive functions. This overview will highlight how these works allow for the quantitative study of processes which underpin alterations in self-experience in schizophrenia, which in turn allows self-experience to be studied as ...
Source: Schizophrenia Research: Cognition - November 6, 2019 Category: Psychiatry Source Type: research

Examining motion speed processing in schizophrenia using the flash lag illusion
Publication date: Available online 31 October 2019Source: Schizophrenia Research: CognitionAuthor(s): Mariia Kaliuzhna, Timo Stein, Philipp Sterzer, Kiley J. SeymourAbstractResearch on visual perception in schizophrenia suggests a deficit in motion processing. Specifically, difficulties with discriminating motion speed are commonly reported. However, speed discrimination tasks typically require participants to make judgments about the difference between two stimuli in a two-interval forced choice (2IFC) task. Such tasks not only tap into speed processing mechanisms, but also rely on higher executive functioning including w...
Source: Schizophrenia Research: Cognition - November 1, 2019 Category: Psychiatry Source Type: research

Cognition and violent behavior in psychotic disorders: A nationwide case-control study
ConclusionImpairments in EFs and ToM are unlikely to provide useful targets for risk assessment and interventions. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 1, 2019 Category: Psychiatry Source Type: research

The characteristics of cognitive neuroscience tests in a schizophrenia cognition clinical trial: Psychometric properties and correlations with standard measures
Publication date: Available online 31 October 2019Source: Schizophrenia Research: CognitionAuthor(s): Michael S. Kraus, James M. Gold, Deanna M. Barch, Trina M. Walker, Charlotte A. Chun, Robert W. Buchanan, John G. Csernansky, Donald C. Goff, Michael F. Green, L. Fredrik Jarskog, Daniel C. Javitt, David Kimhy, Jeffrey A. Lieberman, Joseph P. McEvoy, Raquelle I. Mesholam-Gately, Larry J. Seidman, M. Patricia Ball, Robert S. Kern, Robert P. McMahon, James RobinsonAbstractIn comparison to batteries of standard neuropsychological tests, cognitive neuroscience tests may offer a more specific assessment of discrete neurobiologi...
Source: Schizophrenia Research: Cognition - November 1, 2019 Category: Psychiatry Source Type: research

The association of autistic traits with Theory of Mind and its training efficacy in patients with schizophrenia
Publication date: Available online 31 October 2019Source: Schizophrenia Research: CognitionAuthor(s): Margherita Bechi, Giulia Agostoni, Mariachiara Buonocore, Davide Gritti, Mattia Mascia, Marco Spangaro, Laura Bianchi, Federica Cocchi, Carmelo Guglielmino, Marta Bosia, Roberto CavallaroAbstractLiterature has recently identified a discrete subgroup of patients affected by schizophrenia that also present autistic traits (ATs), showing a peculiar cognitive, clinical and functional profile. Theory of Mind (ToM) represents a core, impaired feature in both schizophrenia and Autism Spectrum Disorder (ASD), ToM in patients with ...
Source: Schizophrenia Research: Cognition - October 31, 2019 Category: Psychiatry Source Type: research

Impaired facial emotion perception of briefly presented double masked stimuli in violent offenders with schizophrenia spectrum disorders
Publication date: Available online 24 October 2019Source: Schizophrenia Research: CognitionAuthor(s): Lennart Högman, Marianne Kristiansson, Håkan Fischer, Anette GM JohanssonAbstractSocial interactions require decoding of subtle rapidly changing emotional cues in others to facilitate socially appropriate behaviour. It is possible that impairments in the ability to detect and decode these signals may increase the risk for aggression. Therefore, we examined violent offenders with schizophrenia spectrum disorders (SSD) and compared these with healthy controls on a computerized paradigm of briefly presented double ...
Source: Schizophrenia Research: Cognition - October 24, 2019 Category: Psychiatry Source Type: research

A systematic review of moderators of cognitive remediation response for people with schizophrenia
ConclusionsThere was no high-quality replicated evidence which identifies reliable moderators of CR response. Many moderators were not replicated or presented in single, underpowered studies. Studies also investigated moderators independently despite their potential to overlap (e.g. age and education). Future research should concentrate on evaluating, with sound studies, the role moderators may play in affecting CR treatment response. This information can inform who will benefit most from the therapy and help to improve the benefits of CR. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - September 6, 2019 Category: Psychiatry Source Type: research

Non-literal understanding and psychosis: Metaphor comprehension in individuals with a diagnosis of schizophrenia
Publication date: December 2019Source: Schizophrenia Research: Cognition, Volume 18Author(s): Felicity Deamer, Ellen Palmer, Quoc C. Vuong, Nicol Ferrier, Andreas Finkelmeyer, Wolfram Hinzen, Stuart WatsonAbstractPrevious studies suggest that understanding of non-literal expressions, and in particular metaphors, can be impaired in people with schizophrenia; although it is not clear why. We explored metaphor comprehension capacity using a novel picture selection paradigm; we compared task performance between people with schizophrenia and healthy comparator subjects and we further examined the relationships between the abili...
Source: Schizophrenia Research: Cognition - August 27, 2019 Category: Psychiatry Source Type: research

Determinants of occupational outcome in recent-onset psychosis: The role of cognition
Publication date: December 2019Source: Schizophrenia Research: Cognition, Volume 18Author(s): William Pothier, Caroline Cellard, Marc Corbière, Patrizia Villotti, Amélie M. Achim, Andréanne Lavoie, Mélissa Turcotte, Chantal Vallières, Marc-André RoyAbstractWorking or studying is a common goal among people with recent-onset psychosis. Cognitive deficits have been reported to influence occupational outcome, but to date few studies have evaluated if cognitive deficits independently predict occupational outcome when taking into account other important determinants, such as self-esteem,...
Source: Schizophrenia Research: Cognition - August 21, 2019 Category: Psychiatry Source Type: research

A comparison of compensatory and restorative cognitive interventions in early psychosis
This study concluded that both CAT and ABCR hold promise as interventions for early intervention psychosis populations but more work is needed to identify illness severity, subtype and contextual considerations that might indicate an emphasis on more compensatory versus more restorative cognitive interventions. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 24, 2019 Category: Psychiatry Source Type: research

Approaches to attenuated psychosis syndrome treatments: A perspective on the regulatory issues
Publication date: December 2019Source: Schizophrenia Research: Cognition, Volume 18Author(s): Luca Pani, Richard S.E. Keefe (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - June 15, 2019 Category: Psychiatry Source Type: research

Publisher's Note
Publication date: September 2019Source: Schizophrenia Research: Cognition, Volume 17Author(s): (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 29, 2019 Category: Psychiatry Source Type: research

Affective prosody and facial emotion recognition in first-episode schizophrenia: Associations with functioning & symptoms
This study aimed to examine how facial emotion and affective prosody recognition are related to functioning and symptoms in a first-episode schizophrenia sample. Further, in light of research suggesting variable emotion-specific performance in people with schizophrenia, this study explored emotion-specific performance. Participants were 49 people with a recent first episode of schizophrenia taking part in a larger RCT. Results revealed that affective prosody recognition was significantly correlated with both role and social functioning. Regarding associations with psychiatric symptoms, facial emotion recognition was signif...
Source: Schizophrenia Research: Cognition - May 26, 2019 Category: Psychiatry Source Type: research

Motivation and engagement during cognitive training for schizophrenia spectrum disorders
ConclusionsObjective measures of treatment engagement were better predictors of treatment outcomes than subjective measures of motivation. Homework completion was most strongly related to treatment outcomes and mediated the relationship between session attendance and treatment outcomes, suggesting continued engagement with cognitive stimulation may be an especially important component of cognitive remediation programs. Future research should examine methods to improve homework completion and session attendance to maximize therapeutic outcomes. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 23, 2019 Category: Psychiatry Source Type: research

Metacognition over time is related to neurocognition, social cognition, and intrapsychic foundations in psychosis
In conclusion, over time, improvements in metacognition across domains co-occur with other core cognitive and social capacities in persons with schizophrenia. As persons became better able to form integrated senses of themselves and adaptively use this knowledge, improvements in neurocognition, social cognition, and intrapsychic foundations were also present. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 17, 2019 Category: Psychiatry Source Type: research

Functional deficits in attenuated psychosis syndrome and related conditions: Current and future treatment options
Publication date: September 2019Source: Schizophrenia Research: Cognition, Volume 17Author(s): Philip D. Harvey, Mackenzie Taylor Jones (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 17, 2019 Category: Psychiatry Source Type: research

Training engagement, baseline cognitive functioning, and cognitive gains with computerized cognitive training: A cross-diagnostic study
Publication date: Available online 13 May 2019Source: Schizophrenia Research: CognitionAuthor(s): Philip D. Harvey, Alexandra M. Balzer, Raymond J. KotwickiAbstractComputerized cognitive training (CCT) interventions are increasing in their use in outpatient mental health settings. These interventions have demonstrated efficacy for improving functional outcomes when combined with rehabilitation interventions. It has recently been suggested that patients with more cognitive impairment have a greater therapeutic response and that reduced engagement in training can identify cases who manifest low levels of benefit from treatme...
Source: Schizophrenia Research: Cognition - May 14, 2019 Category: Psychiatry Source Type: research

What variables predict cognitive remediation associated improvement in individuals with psychosis?
Publication date: Available online 1 May 2019Source: Schizophrenia Research: CognitionAuthor(s): Joanna M. Fiszdon, Matthew M. Kurtz, Lori Parente, Jimmy ChoiAbstractOn average, cognitive remediation (CR) is effective in improving cognitive function in individuals with psychosis, though there is considerable variability in treatment response. No consensus has emerged to date about the potential influence of patient and illness characteristics on CR efficacy. In the current analyses, we examined baseline demographic, cognitive, clinical, and functional ability variables as potential moderators of cognitive improvements duri...
Source: Schizophrenia Research: Cognition - May 3, 2019 Category: Psychiatry Source Type: research

Cognitive and metacognitive factors predict engagement in employment in individuals with first episode psychosis
This study assessed whether metacognition, intellectual aptitude and functional capacity can predict engagement in work and number of hours of work within FEP.MethodsFifty-two individuals with psychosis, from an Early Intervention in Psychosis service, completed measures of IQ, metacognition (Metacognitive Assessment Interview), functional capacity (UPSA), and functional outcome (hours spent in structured activity per week, including employment).ResultsTwenty-six participants (22 males, 4 females) were employed and twenty-six (22 males, 4 females) were not employed. IQ and metacognition were significantly associated with w...
Source: Schizophrenia Research: Cognition - May 3, 2019 Category: Psychiatry Source Type: research

The role of genetics in cognitive remediation in schizophrenia: A systematic review
Publication date: Available online 1 May 2019Source: Schizophrenia Research: CognitionAuthor(s): Rafael Penadés, Marta Bosia, Rosa Catalán, Marco Spangaro, Clemente García-Rizo, Silvia Amoretti, Miquel Bioque, Miquel BernardoAbstractThe role of genetics in cognitive remediation therapies in schizophrenia has not been completely understood yet. Different genes involved in neurotrophic, dopaminergic and serotonin systems have reported to influence cognitive functioning in schizophrenia. These genetic factors could also be contributing to the variability in responsiveness to cognitive treatments. No compr...
Source: Schizophrenia Research: Cognition - May 1, 2019 Category: Psychiatry Source Type: research

Metacognitive function and fragmentation in schizophrenia: Relationship to cognition, self-experience and developing treatments
We describe the rationale and support for one method for quantifying metacognition and its potential to study the fragmentation of a person's sense of themselves, others and the relative place of themselves and others in the larger human community. We summarize research using that method which suggests that deficits in metacognition commonly occur in schizophrenia and are related to basic neurobiological indices of brain functioning. We also present findings indicating that the capacity for metacognition in schizophrenia is positively related to a broad range of aspects of psychological and social functioning when measured...
Source: Schizophrenia Research: Cognition - April 26, 2019 Category: Psychiatry Source Type: research

The synergistic benefits of physical and cognitive exercise in schizophrenia: Promoting motivation to enhance community effectiveness
We present the first community effectiveness data for PE and CT that included a motivationally-enhancing, self-determined approach to exercise, in lieu of participant payment. Eighty-five outpatients with schizophrenia attending an intensive outpatient program were randomized to 18 h of either (A) self-determined PE regimen with choice from a menu of different activities; (B) tablet-based neurofeedback CT focused on processing speed (PS) and working memory (WM), or (C) a time-matched combination of PE and CT. Assessments were conducted at baseline, post, and follow-up (2 mo). All groups improved in WM from baseline to ...
Source: Schizophrenia Research: Cognition - April 26, 2019 Category: Psychiatry Source Type: research

Assessing the potential of longitudinal smartphone based cognitive assessment in schizophrenia: A naturalistic pilot study
DiscussionIt is feasible for those with schizophrenia to use their own smartphones to complete cognitive assessments and other measures related to their mental health. While we did not investigate the correlations between these cognitive assessments and other smartphone captured metrics like step count or self-reported symptoms, the potential to longitudinally assess cognition in the context of patients' environments outside of the clinic presents unique opportunities for characterizing cognitive burden in schizophrenia. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 19, 2019 Category: Psychiatry Source Type: research

Differential improvement of negative-symptom subfactors after cognitive remediation in low-functioning individuals with schizophrenia
This study used the model of expressive and experiential negative symptoms subfactors to decrease this heterogeneity. It examined these subfactors and cognition before and after treatment with computerized cognitive remediation training (CRT) in chronically-hospitalized individuals with psychosis and predominant negative symptoms.MethodsSeventy-eight adult participants with a DSM-IV-TR diagnosis of schizophrenia or schizoaffective disorder were enrolled in a 12-week CRT program. Assessments of demographic and illness variables, baseline and endpoint assessments of psychopathology (Positive and Negative Syndrome Scale) and ...
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Emotion-specific performance across empathy tasks in schizophrenia: Influence of metacognitive capacity
This study aimed to: 1) examine emotion-specific performance on an empathy task, and 2) elucidate associations with four metacognitive domains: self-reflectivity, understanding of others' minds, decentration, and mastery. Fifty-seven people with schizophrenia or schizoaffective disorder participated. All were administered a computerized, performance-based measure of empathy and an interview-based measure of metacognitive capacity. Results revealed that, consistent with research on facial affect recognition, participants performed significantly better when recognizing happiness in empathic stimuli than all other emotions. R...
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Metacognition moderates the relationship between self-reported and clinician-rated motivation in schizophrenia
DiscussionMetacognition appears to be a key variable impacting the strength of the relationship between self-reported and clinician-rated motivation measures and may help to partly explain the varied relationships observed in prior work. Using a metacognitive framework to guide assessment interviews and targeting metacognition in psychosocial treatments may help to improve the synchrony between self-perceptions and clinician ratings of motivation. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Visualizing mental representations in schizophrenia patients: A reverse correlation approach
Conclusion: These novel findings provide a proof of principle that the reverse correlation technique can be applied to investigate mental representations in schizophrenia patients. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 7, 2019 Category: Psychiatry Source Type: research

Social skills, executive functioning and social engagement
Publication date: September 2019Source: Schizophrenia Research: Cognition, Volume 17Author(s): Nir Madjar, Elena Chubarov, Gil Zalsman, Mark Weiser, Gal ShovalAbstractThe study explored hypothesized mediation of social interaction skills between executive functions and social engagement among adolescents diagnosed with schizophrenia. Participants (N = 92; 62% boys; age = 16.8) were assessed four weeks after hospitalization using previously validated scales. A regression mediation analysis followed by Structural Equation Modeling (SEM; with bootstrap analysis) supported the hypothesis. Executive functions were signi...
Source: Schizophrenia Research: Cognition - April 6, 2019 Category: Psychiatry Source Type: research

Cognitive impairment and its improvement after six months in adolescents with schizophrenia
ConclusionsWe observed cognitive impairments on schizophrenic adolescents, which improved after six months of treatment in almost all domains. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 27, 2019 Category: Psychiatry Source Type: research

Association of genetic variants at 22q11.2 chromosomal region with cognitive performance in Japanese patients with schizophrenia
Publication date: Available online 26 March 2019Source: Schizophrenia Research: CognitionAuthor(s): Kazufumi Akiyama, Atsushi Saito, Satoshi Saito, Yuji Ozeki, Takashi Watanabe, Kumiko Fujii, Kazutaka ShimodaAbstract22q11.2 heterozygous multigene deletions confer an increased risk of schizophrenia with marked impairment of cognition. We explored whether genes on 22q11.2 are associated with cognitive performance in patients with idiopathic schizophrenia. A total of 240 schizophrenia patients and 240 healthy controls underwent the Japanese-language version of the Brief Assessment of Cognition in Schizophrenia (BACS) and were...
Source: Schizophrenia Research: Cognition - March 26, 2019 Category: Psychiatry Source Type: research

Disturbed time experience during and after psychosis
Publication date: Available online 21 March 2019Source: Schizophrenia Research: CognitionAuthor(s): D.H.V. Vogel, T. Beeker, T. Haidl, C. Kupke, M. Heinze, K. VogeleyAbstractDisturbances in time experience have been argued to play a significant, if not causative role in the clinical presentation of schizophrenia. Phenomenological considerations suggest a fragmented or dis-articulated time experience causing both primary symptoms such as hallucinations, delusions, and self-disorders, as well as an intersubjective desynchronization. We employed content analysis on material collected from patients diagnosed with schizophrenia...
Source: Schizophrenia Research: Cognition - March 21, 2019 Category: Psychiatry Source Type: research

The continuing story of schizophrenia and schizoaffective disorder: One condition or two?
This study asked whether schizophrenia and schizoaffective disorder are distinguishable on selected cognitive, social cognitive and structural social brain measures. Outpatients with a diagnosis of schizophrenia (n = 44) or schizoaffective disorder (n = 29) and non-psychiatric control participants (n = 62) were studied. Patients were assessed clinically (Positive and Negative Syndrome Scale) and all participants were administered a battery of cognitive (MATRICS Consensus Cognitive Battery; Wechsler Abbreviated Scale of Intelligence, Wide Range Achievement Reading) and social cognitive (Reading the Mind in the E...
Source: Schizophrenia Research: Cognition - February 11, 2019 Category: Psychiatry Source Type: research

Confidence, performance, and accuracy of self-assessment of social cognition: A comparison of schizophrenia patients and healthy controls
This study examines the correlations between performance on a social cognitive test, confidence in performance, effort allocated to the task, and correlates of confidence in patients with schizophrenia and healthy controls (HC). Measures included self-reports of depression, social cognitive ability, and social functioning. A performance-based emotion recognition test assessed social cognitive performance and provided the basis for confidence judgments. Although schizophrenia patients had reduced levels of overall confidence, there was a substantial subset of schizophrenic patients who manifested extreme overconfidence and ...
Source: Schizophrenia Research: Cognition - February 8, 2019 Category: Psychiatry Source Type: research

Limited changes in activities of daily life performance ability among people with schizophrenia at clinical settings and the factors moderating the changes
ConclusionsImpairment of ADL ability is recalcitrant in schizophrenia. The improvement was modest and occurred only in a proportion of participants. However, promisingly, chronic illness, low baseline ADL ability, treatment with clozapine and presence of treatment-resistant schizophrenia did not have an adverse effect on the outcome. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - January 17, 2019 Category: Psychiatry Source Type: research

Modified Work Behavior Inventory assessment: Evaluation of psychometric properties
Publication date: June 2019Source: Schizophrenia Research: Cognition, Volume 16Author(s): Jason E. Peer, Joanna E. Strong Kinnaman, Wendy N. TenhulaAbstractThe Work Behavior Inventory (WBI) is a widely used and validated assessment of work functioning in people with schizophrenia. WBI ratings are based on workplace observation and interview with work supervisors. Workplace observation may not be acceptable in all employment settings. A WBI assessment based only on supervisor interview may offer more utility. The current study evaluated the psychometric properties of a modified WBI among individuals with schizophrenia parti...
Source: Schizophrenia Research: Cognition - January 10, 2019 Category: Psychiatry Source Type: research