Cost of intensive routine control and incremental cost of insecticide-treated curtain deployment in a setting with low Aedes aegypti infestation
CONCLUSIONS At current curtain prices, ITC deployment can hardly be considered an efficient option in Guantanamo and other comparable environments. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - September 2, 2016 Category: Tropical Medicine Source Type: research

Transition of the morbidity and mortality profile in a municipality in the interior of the Brazilian Amazon
CONCLUSIONS These results point to a fragility in the public policies for prevention and awareness of this problem. Infectious and parasitic diseases contribute only 4.5% of deaths, but had the third highest Disa bility-Adjusted Life Year score (1,190 days). Improving support to the Estratégia Saúde da Família (Family Health Strategy) program and implementing a death verification service would significantly aid in reducing the occurrence of non-transmissible chronic diseases and clarifying unknown causes of death. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - September 2, 2016 Category: Tropical Medicine Source Type: research

Pierre Ambroise-Thomas: a loyal friend and a strong supporter of tropical medicine in Brazil
Abstract: Our colleagues at the Sociedade Brasileira de Medicina Tropical have been informed of the demise of Professor Pierre Ambroise-Thomas (1937-2014). However, considering that the tribute we paid to him in 2015 - at the 20th anniversary of the Semin ário Laveran& Deane sobre Mal ária - is equally true today, it is worth sharing it with the readers of the RSBMT, in recognition of his many virtues. Pierre Ambroise-Thomas (MD in 1963 and DSc in 1969) was Honorary Professor of Parasitology and Tropical Medicine at the Faculté de Médecine de Grenoble (France), Honorary Presid ent of the Aca...
Source: Revista da Sociedade Brasileira de Medicina Tropical - September 2, 2016 Category: Tropical Medicine Source Type: research

Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis
Abstract: Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease, problems related to the development of parasite resistance and side effects associated with the compounds used have been noted. Hence, alternative approaches for VL control are desirable. Some methods, such as vector control and culling of infected dogs, are insufficiently effective, with the latter not ethically recommended. The development of vaccines to prevent VL is a feasible and desirable measure for disease control; for example, some vaccines designed to pr...
Source: Revista da Sociedade Brasileira de Medicina Tropical - September 2, 2016 Category: Tropical Medicine Source Type: research

The challenges on developing vaccine against visceral leishmaniasis
(Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - September 2, 2016 Category: Tropical Medicine Source Type: research

Aedes aegypti (Diptera: Culicidae) in a tree hole in Brazil
Abstract: Freshwater stingray injuries are a common problem in the Brazilian Amazon, affecting mostly riverine and indigenous populations. These injuries cause severe local and regional pain, swelling and erythema, as well as complications, such as local necrosis and bacterial infection. Herein, we report a case of bacterial infection and hallux necrosis, after a freshwater stingray injury in the Brazilian Amazon, which eventually required amputation. Different antimicrobial regimens were administered at different stages of the disease; however, avoiding amputation through effective treatment was not achieved. (Source: Rev...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Two cases of lepidopterism caused by indoor exposure to moths
Abstract: Freshwater stingray injuries are a common problem in the Brazilian Amazon, affecting mostly riverine and indigenous populations. These injuries cause severe local and regional pain, swelling and erythema, as well as complications, such as local necrosis and bacterial infection. Herein, we report a case of bacterial infection and hallux necrosis, after a freshwater stingray injury in the Brazilian Amazon, which eventually required amputation. Different antimicrobial regimens were administered at different stages of the disease; however, avoiding amputation through effective treatment was not achieved. (Source: Rev...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Hallux amputation after a freshwater stingray injury in the Brazilian Amazon
Abstract: Freshwater stingray injuries are a common problem in the Brazilian Amazon, affecting mostly riverine and indigenous populations. These injuries cause severe local and regional pain, swelling and erythema, as well as complications, such as local necrosis and bacterial infection. Herein, we report a case of bacterial infection and hallux necrosis, after a freshwater stingray injury in the Brazilian Amazon, which eventually required amputation. Different antimicrobial regimens were administered at different stages of the disease; however, avoiding amputation through effective treatment was not achieved. (Source: Rev...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Chronic kidney disease related to renal tuberculosis: a case report
Abstract: Genitourinary tuberculosis (TB) is the third most common form of extrapulmonary TB. A 34-year-old man with severe kidney function loss secondary to renal TB initially presented with urinary symptoms, including dysuria and polacyuria. The diagnosis was based on clinical history and laboratory tests; the urinalysis revealed acid-fast bacilli. The patient's condition stabilized after beginning TB-specific treatment, but the right kidney function loss persisted. Renal TB can lead to irreversible loss of renal function. As such, renal function should be considered in all patients from TB-endemic areas who present with...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Neurobrucellosis and venous sinus thrombosis: an uncommon association
Abstract: Brucellosis is a commonly diagnosed zoonosis and neurological involvement is rare. A 30-year-old woman presented with a pulsatile headache that was exacerbated by the Valsalva maneuver and refractory to analgesic therapy. The patient also had nausea, cough, and coryza that evolved over 7 days. The neurological examination was unremarkable. Thrombosis of the lateral and sigmoid sinus and ipsilateral internal jugular vein were diagnosed and anticoagulation therapy was started. Brucella spp was identified in a sample of cerebrospinal fluid (CSF); five months after treatment with rifampicin and doxycycline, CSF was s...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Dengue as a cause of fever during pregnancy: a report of two cases
Abstract: Dengue infection has not been routinely investigated among pregnant women and parturients with acute febrile syndrome in endemic settings. Here, we report two cases of dengue fever detected at the time of delivery in parturients enrolled in a cohort prospective study conducted in a hospital in Recife, Brazil. The parturients reported fever onset within seven days prior to delivery, and dengue infection was confirmed upon detection of viral ribonucleic acid (RNA) by using the reverse transcriptase-polymerase chain reaction. Dengue infection should be considered as a diagnostic possibility in cases of fever during ...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

A profile of scorpionism, including the species of scorpions involved, in the State of Amazonas, Brazil
CONCLUSIONS: Our results reaffirm the notion of scorpionism being a public health hazard and provide data that can guide public policy aimed at scorpionism prevention and treatment. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Analysis of cutaneous tuberculosis cases reported from 2000 to 2013 at a university hospital in Rio de Janeiro
CONCLUSIONS: This study confirms the rarity of CTB and highlights the need for multicenter studies in order to obtain an adequate number of cases for analysis. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Semisolid liver infusion tryptose supplemented with human urine allows growth and isolation of Trypanosoma cruzi and Trypanosoma rangeli clonal lineages
CONCLUSIONS SSL-HU medium constitutes a novel tool for obtaining T. cruzi and T. rangeli clonal lineages. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

First report of Rhodnius stali (Hemiptera, Reduviidae, Triatominae) in the State of Acre and in the Brazilian Amazon
CONCLUSIONS: The occurrence of R. stali is worrisome, since this species has been found naturally infected by Trypanosoma cruzi and there has been evidence of its domiciliation capabilities. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.
CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Detection of antibodies to Oropouche virus in non-human primates in Goiânia City, Goiás
CONCLUSIONS This is the first report demonstrating the detection of OROV antibodies in Goiás State and may represent the introduction/circulation of OROV in the region and a potential risk to the human population. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Diversity of yellow fever mosquito vectors in the Atlantic Forest of Rio de Janeiro, Brazil
CONCLUSION: There is a potential for the transmission of arboviruses in and around these natural reserves. Therefore, it is necessary to maintain entomological surveillance programs in the region. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Serological evidence of hantavirus infection in an urban area in Mato Grosso State, Brazil
CONCLUSIONS: Our findings suggest circulation of hantavirus in Sinop. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Performance of POC-CCA® in diagnosis of schistosomiasis mansoni in individuals with low parasite burden
Abstract: INTRODUCTION: Schistosomiasis, caused by Schistosoma mansoni, is a public health concern in Brazil. However, the most popular diagnostic method, the Kato-Katz technique, exhibits low sensitivity in low-endemicity areas. We aimed to compare the performance of an immunological assay, the point-of-care circulating cathodic antigen (POC-CCA®) test, with that of two parasitological techniques in a low-endemicity population. METHODS: Our study included 141 individuals living in Estreito de Miralta, Minas Gerais, Brazil. Fecal samples were obtained from all participants and analyzed for schistosomiasis using two par...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Does my patient have chronic Chagas disease? Development and temporal validation of a diagnostic risk score
CONCLUSIONS: A nomogram and an online calculator (available at http://shiny.ipec.fiocruz.br:3838/pedrobrasil/chronic_chagas_disease_prediction/) were developed to aid in individual risk estimation. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Cardiac rehabilitation program in patients with Chagas heart failure: a single-arm pilot study
CONCLUSIONS: CR was feasible, safe, and has important clinical benefits for patients with CHF, specifically for cardiac function and muscle respiratory strength. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Prevalence and factors associated with Chlamydia trachomatis infection among women with HIV in São Paulo
This study aimed to estimate the prevalence and risk factors associated with Chlamydia trachomatis (CT) infection among women with HIV in São Paulo. METHODS: This cross-sectional study included women with HIV who were receiving care from sixteen public health services in São Paulo (October 2013 to March 2014). All participants answered a questionnaire regarding their sociodemographic, behavioral, and clinical characteristics. A urine sample was tested for CT and Neisseria gonorrhoeae (NG) using the polymerase chain reaction. The chi-square test and a logistic regression model were used to test the association...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Clinical and microbiological features of infections caused by Pseudomonas aeruginosa in patients hospitalized in intensive care units
CONCLUSIONS This study's findings show that P. aeruginosa has a high death rate, and that inadequate treatment and invasive procedures are risk factors for infection. This is the first report describing the detection of the blaSPM-1-like gene in northern Brazil. These results highlight the need for better monitoring and a greater understanding of nosocomial infections and their public health impacts. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Antimicrobial susceptibility of Acinetobacter clinical isolates and emerging antibiogram trends for nosocomial infection management
CONCLUSIONS: The present study showed the alarming trends of resistance of Acinetobacter strains isolated from clinical specimens to the various classes of antimicrobials. The improvement of microbiological techniques for earlier and more accurate identification of bacteria is necessary for the selection of appropriate treatments. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Coagulase-negative staphylococci in Southern Brazil: looking toward its high diversity
CONCLUSIONS: Our results suggest a major shift in SCCmec types within a short period and reveal a different behavior of S. epidermidis with regard to the association between the presence of multiple SCCmec types and MDR profile. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

High prevalence of plasmid-mediated quinolone resistance determinants in Enterobacter cloacae isolated from hospitals of the Qazvin, Alborz, and Tehran provinces, Iran
CONCLUSIONS: This study describes, for the first time, the high prevalence of the qnrB1, qnrS1, and qnrB4 genes among E. cloacae isolates in Iran. The detection of qnr genes emphasizes the need for establishing tactful policies associated with infection control measures in hospital settings in Iran. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Evaluation and optimization of SYBR Green real-time reverse transcription polymerase chain reaction as a tool for diagnosis of the Flavivirus genus in Brazil
CONCLUSIONS: The real-time RT-PCR method may be very useful for preliminary diagnoses in screenings, outbreaks, and other surveillance studies. Moreover, this assay can be easily applied to monitor viral activity and to measure viral load in pathogenesis studies. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Could Plasmodium vivax malaria trigger malnutrition? Revisiting the Bradford Hill criteria to assess a causal relationship between two neglected problems
Abstract: The benign characteristics formerly attributed to Plasmodium vivax infections have recently changed owing to the increasing number of reports of severe vivax malaria resulting in a broad spectrum of clinical complications, probably including undernutrition. Causal inference is a complex process, and arriving at a tentative inference of the causal or non-causal nature of an association is a subjective process limited by the existing evidence. Applying classical epidemiology principles, such as the Bradford Hill criteria, may help foster an understanding of causality and lead to appropriate interventions being prop...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?
Abstract: The Zika virus epidemic that started in Brazil in 2014 has spread to>30 countries and territories in Latin America, leading to a rapid rise in the incidence of microcephalic newborns and adults with neurological complications. At the beginning of the outbreak, little was known about Zika virus morphology, genome structure, modes of transmission, and its potential to cause neurological malformations and disorders. With the advancement of basic science, discoveries of the mechanisms of strain variability, viral transfer to the fetus, and neurovirulence were published. These will certainly lead to the development...
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Serious disease outbreaks caused by viruses transmitted by Aedes aegypti in Brazil
(Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 1, 2016 Category: Tropical Medicine Source Type: research

Cysticerci located in the fourth ventricle causing obstructive hydrocephalus: a radiological emergency requiring prompt diagnosis
We describe two immunocompetent patients who presented with chronic diarrhea that was ultimately found to be caused by continuous exposure to well water contaminated with the microbial cysts (oocysts) of the Cryptosporidium spp parasite. We describe the patients' histories and possible explanations for their prolonged symptoms. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Secondary transmission of cryptosporidiosis associated with well water consumption: two case studies
We describe two immunocompetent patients who presented with chronic diarrhea that was ultimately found to be caused by continuous exposure to well water contaminated with the microbial cysts (oocysts) of the Cryptosporidium spp parasite. We describe the patients' histories and possible explanations for their prolonged symptoms. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Case report of vancomycin-induced pancytopenia
We describe a case of a 56-year-old man who was diagnosed with chronic paraspinal abscess and started on intravenous vancomycin. He was re-admitted two weeks later with new-onset pancytopenia. Discontinuation of vancomycin resulted in improved cell counts. Physicians should monitor cell counts in patients who are on long-term intravenous vancomycin. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Assessment of schistosomiasis in the semi-arid Northeast region of Brazil: the São Francisco River large-scale water transposition project
CONCLUSIONS: There is evidence of active schistosomiasis transmission in the area; thus, intensive surveillance actions are required. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Factors associated with non-adherence to the treatment of vivax malaria in a rural community from the Brazilian Amazon Basin
CONCLUSIONS Treatment interruption is significantly associated with treatment adherence. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

New cases of Chagas disease in a rural area of Northeast Brazilian
CONCLUSIONS: The detection of a case indicated transmission, which was also evidenced by the presence of triatomines and poor housing conditions. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Acceptance and potential barriers to effective use of diagnostic tests for visceral leishmaniasis in an urban area in Brazil
CONCLUSIONS: Patients and healthcare professionals in Ribeirão das Neves demonstrated a high degree of acceptance of the IT LEISH(r) and DAT-LPC. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Prevalence and genotype distribution of human papillomavirus: implications for cancer screening and vaccination in Henan province, China
CONCLUSIONS: The data support close surveillance of women for cervical cancer screening, and HPV prophylactic vaccines including HPV16, HPV 52, and HPV 58 might offer greater protection in this area. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Evaluation of human T-lymphotropic virus prevalence/co-infection rates for a four-year period in a non-metropolitan blood center in Southeast Brazil
CONCLUSIONS: Our findings provide data for the prevalence of HTLV in Brazil and demonstrate the importance of regional and global hemovigilance. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Spatial distribution of disseminated histoplasmosis and AIDS co-infection in an endemic area of Northeastern Brazil
CONCLUSION: Risk factors other than AIDS infection must affect histoplasmosis development in this area. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Knowledge and practices related to dengue and its vector: a community-based study from Southeast Brazil
CONCLUSIONS: The results emphasize the relevance of health education programs, the continuous promotion of educational campaigns in the media, the role of the television as a source of information, and the importance of motivating the population to control the vector. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Two decades of tuberculosis in a city in Northeastern Brazil: advances and challenges in time and space
This study presents two decades of epidemiological data on tuberculosis (TB), in order to understanding the disease profile and its spatiotemporal dynamics. METHODS This descriptive study was performed in the City of Olinda/Pernambuco, Brazil, from 1991-2010, and it analyzed new patients with TB living in the city. We used the χ²-test with a p-value
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Molecular characterization of Mycobacterium tuberculosis isolates from Tehran, Iran by restriction fragment length polymorphism analysis and spoligotyping
CONCLUSIONS A higher prevalence of Ural family MTB isolates among Afghan patients than among Iranian patients suggests the possible transmission of this lineage following the immigration of Afghans to Iran. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Antimonial drugs entrapped into phosphatidylserine liposomes: physicochemical evaluation and antileishmanial activity
CONCLUSIONS: Antimonial drug-containing liposomes are more effective against Leishmania-infected macrophages than the non-liposomal drugs. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Extraction of Trypanosoma cruzi DNA from food: a contribution to the elucidation of acute Chagas disease outbreaks
CONCLUSIONS: The method for T. cruzi detection in food is a powerful tool in the epidemiological investigation of outbreaks as it turns epidemiological evidence into supporting data that serve to confirm T. cruzi infection in the foods. It also facilitates food quality control and assessment of good manufacturing practices involving acai-based products. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Trypanosoma cruzi isolated from a triatomine found in one of the biggest metropolitan areas of Latin America
CONCLUSIONS: Our biological and molecular characterizations helped understand parasite-host interactions and their evolutionary history in context of the associations between vectors, ecotopes, hosts, and groups of the parasite. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Secular trends in Klebsiella pneumoniae isolated in a tertiary-care hospital: increasing prevalence and accelerated decline in antimicrobial susceptibility
CONCLUSIONS Our study indicates that K. pneumoniae has become a major pathogen among hospitalized patients and confirms its recent trend of increasing antimicrobial resistance. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Monoterpene isolated from the essential oil of Trachyspermum ammi is cytotoxic to multidrug-resistant Pseudomonas aeruginosa and Staphylococcus aureus strains
Abstract INTRODUCTION: The aim of this study was to determine whether an herbal extract containing monoterpene exhibited activity against multidrug-resistant Staphylococcus aureus and Pseudomonas aeruginosa isolated from clinical infection samples. METHODS: The essential oil of Trachyspermum ammi (L.) Sprague ex Turrill (Apiaceae) fruit was extracted by hydrodistillation. Fruit residues were treated with hydrochloric acid and re-hydrodistilled to obtain volatile compounds. Compounds in the distilled oil were identified using gas-chromatography (GC) and GC-mass spectrometry (MS). The antibiotic susceptibility of all bacteri...
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research

Over expression of AdeABC and AcrAB-TolC efflux systems confers tigecycline resistance in clinical isolates of Acinetobacter baumannii and Klebsiella pneumoniae
CONCLUSIONS: Tigecycline resistance in A. baumannii and K. pneumoniae was strongly associated with the overexpression of efflux systems. More studies are needed to elucidate whether there are other regulators that affect the expression of adeB in A. baumannii and how ramA affects the expression of acrB in K. pneumoniae. (Source: Revista da Sociedade Brasileira de Medicina Tropical)
Source: Revista da Sociedade Brasileira de Medicina Tropical - May 17, 2016 Category: Tropical Medicine Source Type: research