Machine learning on drug-specific data to predict small molecule teratogenicity
Publication date: Available online 16 May 2020Source: Reproductive ToxicologyAuthor(s): Anup P. Challa, Andrew L. Beam, Min Shen, Tyler Peryea, Robert R. Lavieri, Ethan S. Lippmann, David M. Aronoff (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 18, 2020 Category: Toxicology Source Type: research

Naringin regulates erectile dysfunction by abolition of apoptosis and inflammation through NOS/cGMP/PKG signalling pathway on exposure to Bisphenol-A in hypertensive rat model
Publication date: Available online 16 May 2020Source: Reproductive ToxicologyAuthor(s): J.K. Akintunde, T.E. Akintola, F.H. Aliu, M.O. Fajoye, S.O. Adimchi (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 18, 2020 Category: Toxicology Source Type: research

In utero exposure to arsenite contributes to metabolic and reproductive dysfunction in male offspring of CD-1 mice
Publication date: Available online 17 May 2020Source: Reproductive ToxicologyAuthor(s): Karina Rodriguez, Namya Mellouk, Erica Ungewitter, Barbara Nicol, Chang Liu, Paula R Brown, Cynthia J. Willson, Humphrey H.-C. Yao (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 18, 2020 Category: Toxicology Source Type: research

Olive oil supplementation prevents extracellular matrix deposition and reduces prooxidant markers and apoptosis in the offspring´s heart of diabetic rats
Publication date: Available online 15 May 2020Source: Reproductive ToxicologyAuthor(s): Sabrina L. Roberti, Romina Higa, Hugo Sato, Dalmiro Gomez Ribot, Evangelina Capobianco, Alicia Jawerbaum (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 16, 2020 Category: Toxicology Source Type: research

Developmental exposure to tetrabromobisphenol A has minimal impact on male rat reproductive health
Publication date: Available online 13 May 2020Source: Reproductive ToxicologyAuthor(s): Paula R. Brown, Sagi Enicole A. Gillera, Suzanne E. Fenton, Humphrey Hung-Chang Yao (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 14, 2020 Category: Toxicology Source Type: research

Enhanced normograms and pregnancy outcome analysis in nonhuman primate developmental toxicity studies
Publication date: Available online 13 May 2020Source: Reproductive ToxicologyAuthor(s): Heiko Grossmann, Gerhard F. Weinbauer, Ann Baker, Antje Fuchs, C. Marc Luetjens (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 13, 2020 Category: Toxicology Source Type: research

Pregnancy outcomes in patients treated with leflunomide, the parent compound of the multiple sclerosis drug teriflunomide
Publication date: Available online 11 May 2020Source: Reproductive ToxicologyAuthor(s): Lily J. Henson, Salman Afsar, Lynn Davenport, Annie Purvis, Elizabeth M. Poole, Philippe Truffinet (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 12, 2020 Category: Toxicology Source Type: research

Vascular and inflammatory effects of estrogen and anti-androgen therapy in the testis and epididymis of male to female transgender adults
Publication date: Available online 11 May 2020Source: Reproductive ToxicologyAuthor(s): Cristina Peña Barreno, Pilar Gonzalez-Peramato, Manuel Nistal (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 12, 2020 Category: Toxicology Source Type: research

“Real life” polycyclic aromatic hydrocarbon (PAH) mixtures modulate hCG, hPL and hPLGF levels and disrupt the physiological ratio of MMP-2 to MMP-9 and VEGF expression in human placenta cell lines
Publication date: Available online 11 May 2020Source: Reproductive ToxicologyAuthor(s): Eliza Drwal, Agnieszka Rak, Wacław Tworzydło, Ewa Łucja Gregoraszczuk (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 11, 2020 Category: Toxicology Source Type: research

Effects of single and repetitive valproic acid administration on the gene expression of placental transporters in pregnant rats: An analysis by gestational perio
Publication date: Available online 11 May 2020Source: Reproductive ToxicologyAuthor(s): Naoko Jinno, Ayako Furugen, Yuko Kurosawa, Yuki Kanno, Katsuya Narumi, Masaki Kobayashi, Ken Iseki (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 11, 2020 Category: Toxicology Source Type: research

Prenatal exposure to phthalates and male reproductive system development: results from a Canadian pregnancy cohort study
Publication date: Available online 5 May 2020Source: Reproductive ToxicologyAuthor(s): Rodrigo L.P. Romao, Linda Dodds, Jillian Ashley-Martin, Patricia Monnier, Tye E. Arbuckle (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - May 5, 2020 Category: Toxicology Source Type: research

Sex- and age-dependent effects of maternal organophosphate flame-retardant exposure on neonatal hypothalamic and hepatic gene expression
Publication date: Available online 29 April 2020Source: Reproductive ToxicologyAuthor(s): Samantha Adams, Kimberly Wiersielis, Ali Yasrebi, Kristie Conde, Laura Armstrong, Grace L. Guo, Troy A. Roepke (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - April 30, 2020 Category: Toxicology Source Type: research

Associations of exposure to phthalates and environmental phenols with gynecological disorders
Publication date: Available online 28 April 2020Source: Reproductive ToxicologyAuthor(s): Jangwoo Lee, Yunsun Jeong, Sori Mok, Kyungho Choi, Jeongim Park, Hyo-Bang Moon, Gyuyeon Choi, Hai-Joong Kim, Su Young Kim, Sooran Choi, Sungkyoon Kim (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - April 29, 2020 Category: Toxicology Source Type: research

Computational approach for collection and prediction of molecular initiating events in developmental toxicity
Publication date: Available online 26 April 2020Source: Reproductive ToxicologyAuthor(s): Xabier Cendoya, Celia Quevedo, Maitane Ipiñazar, Francisco J. Planes (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - April 29, 2020 Category: Toxicology Source Type: research

The aryl hydrocarbon receptor mediates sex ratio distortion in the embryos sired by TCDD-exposed male mice
Publication date: Available online 23 April 2020Source: Reproductive ToxicologyAuthor(s): Kristin M. Bircsak, Latresa T. Copes, Sara King, Andrew M. Prantner, Wei-Ting Hwang, George L. Gerton (Source: Reproductive Toxicology)
Source: Reproductive Toxicology - April 24, 2020 Category: Toxicology Source Type: research