Patients’ view of the differences in topical creams for radiation dermatitis prevention. A pilot study of cosmetic properties
ConclusionsTopical agents for preventive ARD are reported by patients to show different cosmetic properties. Cosmetic properties are important when choosing topical agents for ARD prevention. Recommending those with better cosmetic profiles would improve patient adherence to treatments. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - June 7, 2019 Category: Cancer & Oncology Source Type: research

MC safe bunker designing for an 18 MV linac with nanoparticles included primary barriers and effect of the nanoparticles on the shielding aspects
ConclusionsIt was concluded that application of some nanoparticles in the shielding materials structures in megavoltage radiotherapy can make the shielding effective. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - June 6, 2019 Category: Cancer & Oncology Source Type: research

MRI in medical practice and its future use in radiation oncology. Resume of XXV GOCO Congress (Montpellier) 2017
Publication date: July–August 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 4Author(s): Xavier Druet, Estrella Acosta Sanchez, Ken Soleakhena, Anne Laprie, Jordi Sáez, Stéphanie Nougaret, Olivier Riou, Elodie Rigal, Laura Kibranian, Miguel Palacios, Ismael MembriveAbstractThis publication is a resume of the GOCO Congress (Montpellier 2017). A part of this congress was about the use of MRI in clinical practice, focused on the oncology field. The role of this tool was described in diagnosis, staging of tumors, evaluation of treatment response and the future use in prognost...
Source: Reports of Practical Oncology and Radiotherapy - June 6, 2019 Category: Cancer & Oncology Source Type: research

Successful treatment of refractory chylous ascites due to follicular lymphoma with very low-dose radiotherapy
Publication date: July–August 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 4Author(s): Márcio Tavares, Sofia Ramalheira, Sérgio Chacim, Rui Henrique, Ângelo Oliveira, José Mário MarizAbstractChylous ascites is an extremely rare complication of lymphoma. Here, we discuss the case of a patient presenting with refractory chylous ascites due to a massive retroperitoneal follicular lymphoma, staged as IVB. The patient was unresponsive to chemoimmunotherapy, which prompted us to consider alternative treatment strategies. Low-dose radiotherapy was initiated...
Source: Reports of Practical Oncology and Radiotherapy - June 4, 2019 Category: Cancer & Oncology Source Type: research

Adoption of an incident learning system in a regionally expanding academic radiation oncology department
We describe a successful implementation of a departmental incident learning system (ILS) across a regionally expanding academic radiation oncology department, dovetailing with a structured integration of the safety and quality program across clinical sites.Materials and methods mOver 6 years between 2011 and 2017, a long-standing departmental ILS was deployed to 4 clinical locations beyond the primary clinical location where it had been established. We queried all events reported to the ILS during this period and analyzed trends in reporting by clinical site. The chi-square test was used to determine whether differences ov...
Source: Reports of Practical Oncology and Radiotherapy - June 2, 2019 Category: Cancer & Oncology Source Type: research

Determination of initial electron parameters by means of Monte Carlo simulations for the Siemens Artiste Linac 6 MV photon beam
ConclusionsThe initial parameters especially depend on components of a linac head. The phase space file which was obtained from Monte Carlo Simulation for a linac can be used as calculation of scattering, MLC leakage, to compare dose distribution on patients and in various studies. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - June 1, 2019 Category: Cancer & Oncology Source Type: research

Dosimetric comparison of conformal technique (3D) with volumetric modulated arc therapy with respect to doses obtained in the temporal lobe area in patients irradiated for brain meningioma
ConclusionApplication of VMAT in patients treated for meningioma of the brain is not related to higher doses of radiation in the temporal lobe area, compared with the conformal technique. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - June 1, 2019 Category: Cancer & Oncology Source Type: research

Skin surface markers for stereotactic body radiation therapy of sternal metastasis
Publication date: July–August 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 4Author(s): Hossein Hemmatazad, Daniel Schmidhalter, Olgun Elicin, Daniel M. Aebersold, Evelyn HerrmannAbstractStereotactic body radiation therapy is an effective and safe treatment modality for bone metastasis which allows clinicians to accurately target lesions to high doses while minimizing dose to organs at risk. The commercially available CyberKnife® Xsight™ Spine Tracking System (Accuray, Inc., Sunnyvale, CA) tracks static skeletal structures and eliminates the need for implanted fiducial marke...
Source: Reports of Practical Oncology and Radiotherapy - June 1, 2019 Category: Cancer & Oncology Source Type: research

Definitive, intensity modulated tomotherapy with a simultaneous integrated boost for prostate cancer patients – Long term data on toxicity and biochemical control
ConclusionSIB-IMRT using daily MV-CT guidance showed excellent long-term biochemical control and low toxicity rates. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - May 30, 2019 Category: Cancer & Oncology Source Type: research

Superparamagnetic iron oxide nanoparticles (SPIONs) as a multifunctional tool in various cancer therapies
Publication date: July–August 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 4Author(s): Marika Musielak, Igor Piotrowski, Wiktoria M. SuchorskaAbstractOver the past two decades nanotechnology has become an important part of novel medical research. Researchers have made great progress in developing nanotechnology applications used for detecting and treating oncological diseases. Recently, many research groups have focused on the use of superparamagnetic iron oxide nanoparticles (SPIONs) in cancer treatment. Due to the range of therapeutic properties and possibilities of various modific...
Source: Reports of Practical Oncology and Radiotherapy - May 21, 2019 Category: Cancer & Oncology Source Type: research

Editorial board
Publication date: May–June 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 3Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - May 17, 2019 Category: Cancer & Oncology Source Type: research

Late toxicity for prostate cancer patients treated with hypofractionated helical tomotherapy
ConclusionsHypofractionated HT can be delivered safely with limited rates of moderate and severe late toxicity. The proportion of the rectum that receives a moderate and high dose, having comorbidities, and PSA at diagnosis seem to associate with long term toxicity. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - May 9, 2019 Category: Cancer & Oncology Source Type: research

Use of the g-index for assessment of citation-based scholarly activity of United States radiation oncology residents and subsequent choice of academic versus private practice career
Publication date: May–June 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 3Author(s): Shearwood McClelland III, Timur Mitin, Nima Nabavizadeh, Clifton David Fuller, Charles R. Thomas Jr, Jerry J. JaboinAbstractIntroductionThe Hirsch index (h-index) evaluates citation-based scholarly activity, but has limited ability to acknowledge those publishing a smaller number of manuscripts with exceedingly high citations. The g-index addresses this limitation by assessing the largest number of manuscripts (g) by an author cited at least (g × g) times, but has yet to be applied to ...
Source: Reports of Practical Oncology and Radiotherapy - May 1, 2019 Category: Cancer & Oncology Source Type: research

Estimation of tumor and local tissue dose in gold nanoparticles radiotherapy for prostate cancer
ConclusionsAccording to the MCNP results, 198AuNPs are a promising modality to treat prostate cancer and other cancers and 199AuNPs could be used for imaging purposes. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - April 10, 2019 Category: Cancer & Oncology Source Type: research

Analysis of pre-residency research productivity, dual degree status, and gender distribution of underrepresented minorities among a current United States radiation oncology junior resident class
ConclusionUnderrepresented minorities were comparable to the remainder of their Radiation Oncology resident class regarding gender distribution, dual degrees status, and likelihood of having at least two peer-reviewed publications cited in PubMed during the calendar year of residency application. Further studies will be needed to determine how these findings translate into future scholarly activity and post-graduate career choice. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - April 7, 2019 Category: Cancer & Oncology Source Type: research

Radiation oncology crossword: Genitourinary cancer
Publication date: May–June 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 3Author(s): Shearwood McClelland, Timur Mitin, Charles R. Thomas (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - April 7, 2019 Category: Cancer & Oncology Source Type: research

On the use of AAA and AcurosXB algorithms for three different stereotactic ablative body radiotherapy (SABR) techniques: Volumetric modulated arc therapy (VMAT), intensity modulated radiation therapy (IMRT) and 3D conformal radiotherapy (3D-CRT)
ConclusionThis study showed that the treatment planning results obtained using the Acuros XB algorithm was better than those using the AAA algorithm in SABR lung radiotherapy. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 25, 2019 Category: Cancer & Oncology Source Type: research

Enhanced dermatologic toxicity following concurrent treatment with palbociclib and radiation therapy: A case report
ConclusionThis case highlights the importance of using caution when combining radiation with the new targeted therapies. Until more data becomes available, physicians are recommended to exercise clinical judgment when deciding on whether to continue or discontinue a CDK4/6 inhibitor in a patient who may need radiation. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 22, 2019 Category: Cancer & Oncology Source Type: research

Adaptive radiotherapy in patients receiving neoadjuvant radiation for soft tissue sarcoma
ConclusionsChange in soft tissue sarcoma volume during radiation is not uncommon. Image guidance should be used to reduce setup errors and to detect differences in tumor volume. Image guidance and adaptive radiation are paramount to ensure optimal radiation delivery. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 19, 2019 Category: Cancer & Oncology Source Type: research

Modulated volumetric arc therapy for total marrow irradiation: A feasibility study in the oncology hospital of CMN SXXI from a medical physics approach
ConclusionThe results analysis shows that the proposed TMI technique is feasible and applicable in the Mexican public health system. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 19, 2019 Category: Cancer & Oncology Source Type: research

Editorial board
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 15, 2019 Category: Cancer & Oncology Source Type: research

Validation of dose distribution computation on sCT images generated from MRI scans by Philips MRCAT
ConclusionsThe dose calculation accuracy on MRCAT was not significantly compromised in the majority of clinical relevant DVH points. The introduction of MRCAT into practise would eliminate systematic errors, increase patients’ comfort and reduce treatment expenses. Institutions interested in MRCAT commissioning must, however, consider changes to established workflow. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 4, 2019 Category: Cancer & Oncology Source Type: research

Calculation and measurement of doses in the surface layers of a phantom when using Tomotherapy
ConclusionThe analysis of results showed that the relative percentage difference between measured and planned dose in the field of irradiation was less than 10%, while the largest differences were on the board of the field of radiation and outside of the field of irradiation, where the dose was 0.08 Gy to 1 Gy. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - March 4, 2019 Category: Cancer & Oncology Source Type: research

Management of interruptions in radiotherapy treatments: Adaptive implementation in high workload sites
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Gustavo Pozo, Maria Angeles Pérez-Escutia, Ana Ruíz, Alejandro Ferrando, Ana Milanés, Eduardo Cabello, Raul Díaz, Alejandro Prado, Jose Fermin Pérez-RegaderaAbstractOwing to predictable or unpredictable causes, interruptions may arise during therapy. On average, the extension of fractionated radiotherapy treatments is prone to be delayed by several weeks and interruptions can come up extending overall treatment time (OTT). Clonogenic cells of aggressive tumors mig...
Source: Reports of Practical Oncology and Radiotherapy - February 27, 2019 Category: Cancer & Oncology Source Type: research

Effect of image quality on correlation modeling error using a fiducial marker in a gimbaled linear accelerator
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Hideharu Miura, Shuichi Ozawa, Tsubasa Enosaki, Fumika Hosono, Kiyoshi Yamada, Yasushi NagataAbstractThe purpose of this study was to investigate the effect of image quality under various imaging parameters (60, 70, 80, 90, 100, 110, and 120 kV at 200 mA and 10 ms/63, 80, 100, 160, 200, 250, and 320 mA at 120 kV and 10 ms) and the diameter of the fiducial marker (0.25, 0.50, 0.75, and 1.10 mm) on the correlation modeling error for dynamic tumor tracking (DTT) in t...
Source: Reports of Practical Oncology and Radiotherapy - February 27, 2019 Category: Cancer & Oncology Source Type: research

Performance of the eclipse monitor unit objective tool utilizing volumetric modulated arc therapy for rectal cancer
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Alejandro Prado, Ángel Gaitán, Mario Leonor, Marta Manzano, Eduardo Cabello, Raúl Díaz, Alejandro Ferrando, Ana Milanés, Gustavo PozoAbstractAimTo assess the performance of the monitor unit (MU) Objective tool in Eclipse treatment planning system (TPS) utilizing volumetric modulated arc therapy (VMAT) for rectal cancer.BackgroundEclipse VMAT planning module includes a tool to control the number of MUs delivered: the MU Objective tool. This tool could be utilized t...
Source: Reports of Practical Oncology and Radiotherapy - February 26, 2019 Category: Cancer & Oncology Source Type: research

Investigation of the changes in the prostate, bladder, and rectal wall sizes during external beam radiotherapy
ConclusionsThe volume of the bladder wall decreased during IMRT. The range of subtraction of the volume of the bladder wall was extensive. Thus, the estimation of the bladder wall may be useful to reduce the inter-fraction variation. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 23, 2019 Category: Cancer & Oncology Source Type: research

Radiopotentiation of enzalutamide over human prostate cancer cells as assessed by real-time cell monitoring
ConclusionsThese results provide evidence that the enzalutamide/radiotherapy combination could maximize therapeutic responses in patients with enzalutamide-sensitive prostate cancer. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 23, 2019 Category: Cancer & Oncology Source Type: research

A review of automatic lung tumour segmentation in the era of 4DCT
ConclusionAuto-contouring is reliable and efficient, producing accurate contours with better consistency compared to manual contours. However, manual inputs would still be required both before and after auto-propagation. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 23, 2019 Category: Cancer & Oncology Source Type: research

The case for radiotherapy in a Value based environment
ConclusionsIn the United States, stabilizing costs in the face of increasing work, better outcomes, and decreased toxicity contributes to increasing RT value over the past 10 years. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 21, 2019 Category: Cancer & Oncology Source Type: research

Dosimetric impact of statistical uncertainty on Monte Carlo dose calculation algorithm in volumetric modulated arc therapy using Monaco TPS for three different clinical cases
ConclusionFor VMAT plans, SU can be accepted from 1% to 3% per plan with reduced calculation time without compromising plan quality and deliverability by accepting variations in point dose within the target. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 19, 2019 Category: Cancer & Oncology Source Type: research

Gene delivery methods and genome editing of human pluripotent stem cells
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Patrycja Czerwińska, Sylwia Mazurek, Iga Kołodziejczak, Maciej WiznerowiczAbstractInduced pluripotent stem cells derived from normal somatic cells could be utilized to study tumorigenesis through overexpression of specific oncogenes, downregulation of tumor suppressors and dysregulation of other factors thought to promote tumorigenesis. Therefore, effective approaches that provide direct modifications of induced pluripotent stem cell genome are extremely needed. Emerging strategies are expected t...
Source: Reports of Practical Oncology and Radiotherapy - February 19, 2019 Category: Cancer & Oncology Source Type: research

Variables altering the impact of respiratory gated CT simulation on planning target volume in radiotherapy for lung cancer
ConclusionThe use of 4D-simulation reduces the PTV for the primary tumor in lung cancer cases. Further studies with larger samples are required to confirm the benefit of 4D-simulation in decreasing PTV in lung cancer. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 17, 2019 Category: Cancer & Oncology Source Type: research

Effectiveness of different accelerated partial breast irradiation techniques for the treatment of breast cancer patients: Systematic review using indirect comparisons of randomized clinical trials
ConclusionsBased on indirect comparisons, no differences in clinical outcomes were observed among diverse APBI techniques in published clinical trials that formally compared WBI to APBI. However wide confidence intervals and high risk of inconsistency precluded a sound conclusion. Further head-to-head clinical trials comparing different APBI techniques are required to confirm our findings. Studies comparing different techniques using individual participant data and/or real-life data from population-based studies/registries could also provide more robust results. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 16, 2019 Category: Cancer & Oncology Source Type: research

In vivo dosimetry of the rectum in image-guided adaptive interstitial-intracavitary brachytherapy of cervix cancer – A feasibility study
ConclusionsUnder treatment conditions, the semiconductor diode does not provide reliable measured data. The probe pushes the rectal wall closer to the high dose areas and underestimates the dose of it. Semiconductor probe is not recommended for in vivo dosimetry of the rectum in image-guided brachytherapy of cervical cancer. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - February 15, 2019 Category: Cancer & Oncology Source Type: research

Radiosensitizing properties of magnetic hyperthermia mediated by superparamagnetic iron oxide nanoparticles (SPIONs) on human cutaneous melanoma cell lines
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Jakub Dalibor RybkaAbstractMelanoma is responsible for the majority of deaths related to skin cancer. Worryingly, prognoses show an increasing number of melanoma cases each year worldwide. Radiotherapy, which is a cornerstone of cancer treatment, has proved to be useful but insufficient in melanoma management due to exceptionally high radioresistance of melanoma cells. This problem could be overcome by superparamagnetic iron oxide nanoparticles (SPIONs) used as heat mediators in magnetic hypertherm...
Source: Reports of Practical Oncology and Radiotherapy - February 7, 2019 Category: Cancer & Oncology Source Type: research

Corrigendum to “Why should radiation oncology do translational research?” [Rep Pract Oncol Radiother 2019;24(1):60–64]
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Rut Cañas, Isabel Linares, Ferran Guedea, Miguel Ángel Berenguer Francés (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - January 25, 2019 Category: Cancer & Oncology Source Type: research

Local control rates in stereotactic body radiotherapy (SBRT) of lung metastases associated with the biologically effective dose
Publication date: March–April 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 2Author(s): Daniel Zucca Aparicio, Ovidio Hernando Requejo, Miguel Ángel de la Casa de Julián, Carmen Rubio Rodríguez, Pedro Fernández LetónAbstractAimTo evaluate dose differences in lung metastases treated with stereotactic body radiotherapy (SBRT), and the correlation with local control, regarding the dose algorithm, target volume and tissue density.BackgroundSeveral studies showed excellent local control rates in SBRT for lung metastases, with different fractionation schem...
Source: Reports of Practical Oncology and Radiotherapy - January 23, 2019 Category: Cancer & Oncology Source Type: research

Improved error detection using a divided treatment plan in volume modulated arc therapy
ConclusionThe error discrimination ability was improved by dividing and verifying the portal imaging. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - January 23, 2019 Category: Cancer & Oncology Source Type: research

Editorial board
Publication date: January–February 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 1Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - January 20, 2019 Category: Cancer & Oncology Source Type: research

Editorial board
Publication date: November–December 2018Source: Reports of Practical Oncology & Radiotherapy, Volume 23, Issue 6Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 1, 2018 Category: Cancer & Oncology Source Type: research

Acknowledgement of reviewers
Publication date: November–December 2018Source: Reports of Practical Oncology & Radiotherapy, Volume 23, Issue 6Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 1, 2018 Category: Cancer & Oncology Source Type: research

Dosimetric and Monte Carlo verification of jaws-only IMRT plans calculated by the Collapsed Cone Convolution algorithm for head and neck cancers
ConclusionsAccording to the results, it is concluded that the CCC algorithm was adequate for most of the IMRT H&N cases where the target was not immediately adjacent to the critical structures. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 29, 2018 Category: Cancer & Oncology Source Type: research

Patterns of post-operative irradiation in breast cancer patients submitted to neoadjuvant chemotherapy
ConclusionsAfter NAC, most patients received irradiation of the breast/chest wall and axillary and supraclavicular nodes. In this setting, PORT to breast/chest wall with or without regional nodal irradiation was safe and effective, with acceptable disease-free and overall survival rates reported in this high-risk population. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 29, 2018 Category: Cancer & Oncology Source Type: research

Multi-institutional evaluation using the end-to-end test for implementation of dynamic techniques of radiation therapy in Thailand
ConclusionsThe 8 participating RT centers achieved a satisfactory quality level of IMRT/VMAT clinical implementation. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 29, 2018 Category: Cancer & Oncology Source Type: research

Tracking, gating, free-breathing, which technique to use for lung stereotactic treatments? A dosimetric comparison
ConclusionsEvery technique provides plans with a good target coverage and lung protection. While irradiation with free-breathing increases doses to GTV, irradiation with the tracking technique spares better the lung but can dramatically increase the treatment complexity. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 25, 2018 Category: Cancer & Oncology Source Type: research

Adjuvant gamma knife surgery and image-guided, intensity-modulated radiation therapy for the treatment of sacral chordomas
ConclusionsWe confirmed that adjuvant radiotherapy improved RFS but not OS in sacral chordoma patients after surgery. Furthermore, favorable RFS and low adverse event rates were observed following IG-IMRT. Our results suggest that high dose IG-IMRT is an appropriate module of adjuvant radiotherapy for sacral chordoma patients. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 23, 2018 Category: Cancer & Oncology Source Type: research

Dose to pelvic lymph nodes in image based high dose rate brachytherapy of carcinoma cervix
ConclusionsThere is a significant dose contribution to the pelvic lymph nodal groups during intracavitary brachytherapy. There is a low degree of correlation between point B dose and dosimetric parameters of the individual nodal groups. Hence, it is important to analyse the dose delivered to individual nodal groups during intracavitary brachytherapy, at least in patients with enlarged lymph nodes to calculate the cumulative dose delivered. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 23, 2018 Category: Cancer & Oncology Source Type: research

Nanoparticles as a promising method to enhance the abscopal effect in the era of new targeted therapies
Publication date: January–February 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 1Author(s): Ignacio Morales-Orue, Rodolfo Chicas-Sett, Pedro C. LaraAbstractOver the last decade, immunotherapy has emerged as a hopeful alternative in cancer therapy. Different drugs are used to stimulate the immune system and block negative immune regulatory pathways, known as “immune checkpoint inhibitors (ICI)”. Although clinical studies have reported efficacy and safety with the use of ICI, only a small group of patients have obtained a clinical benefit. Because of this, immunomodulation ...
Source: Reports of Practical Oncology and Radiotherapy - November 23, 2018 Category: Cancer & Oncology Source Type: research

Analysis of a volumetric-modulated arc therapy (VMAT) single phase prostate template as a class solution
Publication date: January–February 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 1Author(s): Matthew Hoffmann, Jacqueline Pacey, Josie Goodworth, Andrea Laszcyzk, Richard Ford, Brendon Chick, Stuart Greenham, Justin WesthuyzenAbstractAimTo assess a class solution template for volumetric-modulated arc therapy (VMAT) for prostate cancer using plan analysis software.BackgroundVMAT is a development of intensity-modulated radiotherapy (IMRT) with potential advantages for the delivery of radiotherapy (RT) in prostate cancer. Class solutions are increasingly used for facilitating RT planning...
Source: Reports of Practical Oncology and Radiotherapy - November 23, 2018 Category: Cancer & Oncology Source Type: research