Determination of “Fitness-for-Purpose” of Quantitative Structure-Activity Relationship (QSAR) Models to Predict (Eco-)Toxicological Endpoints for Regulatory Use
Publication date: Available online 9 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Samuel J. Belfield, Steven J. Enoch, James W. Firman, Judith C. Madden, Terry W. Schultz, Mark T.D. Cronin (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 10, 2021 Category: Toxicology Source Type: research

The Evolution of SEND at AstraZeneca
Publication date: Available online 8 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Claire Kent, Brett Coupland, Claire Barnard, Jason Schofield, Shameen Afif-Rider (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 9, 2021 Category: Toxicology Source Type: research

Developing a Database of Systematic Reviews of Animal Studies
Publication date: Available online 6 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Miranda W. Langendam, Kristen Magnuson, Ashley R. Williams, Vickie R. Walker, Kembra L. Howdeshell, Andrew A. Rooney, Carlijn R. Hooijmans (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 6, 2021 Category: Toxicology Source Type: research

Editorial Board
Publication date: June 2021Source: Regulatory Toxicology and Pharmacology, Volume 122Author(s): (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 6, 2021 Category: Toxicology Source Type: research

Use of An Animal Model of Disease for Toxicology Enables Identification of a Juvenile No Observed Adverse Effect Level for Cyclocreatine in Creatine Transporter Deficiency
Publication date: Available online 4 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Minh-Ha T. Do, Joy Cavagnaro, Mark Butt, Pramod S. Terse, John C. McKew (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 6, 2021 Category: Toxicology Source Type: research

Safety evaluation of BPL9K-4 rice in a subchronic rodent feeding study
Publication date: Available online 30 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Yuzhe Li, Chunlai Liang, Jing Hu, Xue Geng, Haibo Liu, Yongquan Feng, Yuan Zhi, Zhou Yu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2021 Category: Toxicology Source Type: research

Comprehensive Investigation Evaluating the Carcinogenic Hazard Potential of Acetaminophen
Publication date: Available online 30 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Jay E. Sirois (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2021 Category: Toxicology Source Type: research

Support vector machine-based model for toxicity of organic compounds against fish
Publication date: Available online 30 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Xinliang Yu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2021 Category: Toxicology Source Type: research

Fertility and early embryonic development toxicity assessment of naringin in Sprague-Dawley rats
Publication date: Available online 29 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Yonggang Wang, Hao Wu, Pan Chen, Weiwei Su, Wei Peng, Peibo Li (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 29, 2021 Category: Toxicology Source Type: research

A comprehensive review of mechanistic insights into formaldehyde-induced nasal cavity carcinogenicity
Publication date: Available online 24 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Akiyoshi Nishikawa, Kasuke Nagano, Hajime Kojima, Kumiko Ogawa (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 25, 2021 Category: Toxicology Source Type: research

New Framework for a Non-Animal Approach Adequately Assures the Safety of Cosmetic Ingredients – A Case Study on Caffeine
Publication date: Available online 24 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Dagmar Bury, Camilla Alexander-White, Harvey J. Clewell, Mark Cronin, Bertrand Desprez, Ann Detroyer, Alina Efremenko, James Firman, Eric Hack, Nicola J. Hewitt, Gerry Kenna, Martina Klaric, Cathy Lester, Catherine Mahony, Gladys Ouedraogo, Alicia Paini, Andreas Schepky (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 25, 2021 Category: Toxicology Source Type: research

Next Generation Risk Assessment for Skin Sensitisation: A Case Study with Propyl Paraben
Publication date: Available online 24 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Hind Assaf Vandecasteele, Françoise Gautier, Fleur Tourneix, Erwin van Vliet, Dagmar Bury, Nathalie Alépée (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 25, 2021 Category: Toxicology Source Type: research

A simplified index to quantify the irritation/corrosion potential of chemicals – Part II: Eye
Publication date: Available online 24 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Carole CHARMEAU-GENEVOIS, Satinder SARANG, Mélissa PEREA, Nathalie MAYER, Charles EADSFORTH, Tom AUSTIN, Paul THOMAS (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 24, 2021 Category: Toxicology Source Type: research

Subchronic Oral Toxicity Study of Rhubarb Extract in Sprague-Dawley Rats
Publication date: Available online 21 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Chunxia Liu, Ji Liu, Yanhua Zheng, Jingjing Qu, Wenxiang Yang, Xiaoqiao Tang, Hong Bai, Bolin Fan (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 22, 2021 Category: Toxicology Source Type: research

Comparisons of PNEC Derivation Logic Flows Under Example Regulatory Schemes and Implications for ecoTTC
Publication date: Available online 20 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): S.E. Belanger, A. Beasley, J.L. Brill, J. Krailler, K.A. Connors, G.J. Carr, M. Embry, M.G. Barron, R. Otter, A. Kienzler (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 21, 2021 Category: Toxicology Source Type: research