A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease
Publication date: Available online 18 March 2020Source: Progress in NeurobiologyAuthor(s): Tyler B. Johnson, Jon J. Brudvig, Kimmo K. Lehtimäki, Jacob T. Cain, Katherine A. White, Timo Bragge, Jussi Rytkönen, Tuulia Huhtala, Derek Timm, Maria Vihma, Jukka T. Puoliväli, Pekka Poutiainen, Antti Nurmi, Jill M. Weimer (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 18, 2020 Category: Neuroscience Source Type: research
Changes in human brain dynamics during behavioral priming and repetition suppression
Publication date: Available online 18 March 2020Source: Progress in NeurobiologyAuthor(s): Anna Korzeniewska, Yujing Wang, Heather L. Benz, Matthew S. Fifer, Max Collard, Griffin Milsap, Mackenzie C. Cervenka, Alex Martin, Stephen J. Gotts, Nathan E. Crone (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 18, 2020 Category: Neuroscience Source Type: research
Editorial Board
Publication date: April 2020Source: Progress in Neurobiology, Volume 187Author(s): (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 15, 2020 Category: Neuroscience Source Type: research
Primary afferent-driven presynaptic inhibition of C-fiber inputs to spinal lamina I neurons
Publication date: Available online 12 March 2020Source: Progress in NeurobiologyAuthor(s): E.C. Fernandes, C. Pechincha, L.L. Luz, E. Kokai, P. Szucs, B.V. Safronov (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 13, 2020 Category: Neuroscience Source Type: research
Network neuroscience of apathy in cerebrovascular disease
Publication date: Available online 6 March 2020Source: Progress in NeurobiologyAuthor(s): Jonathan Tay, Danuta M. Lisiecka-Ford, Matthew J. Hollocks, Anil M. Tuladhar, Thomas R. Barrick, Anne Forster, Michael J. O’Sullivan, Masud Husain, Frank-Erik de Leeuw, Robin G. Morris, Hugh S. Markus (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 7, 2020 Category: Neuroscience Source Type: research
A thermodynamic function of glycogen in brain and muscle
Publication date: Available online 6 March 2020Source: Progress in NeurobiologyAuthor(s): Raymond A. Swanson (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 7, 2020 Category: Neuroscience Source Type: research
Platelets promote epileptic seizures by modulating brain serotonin level, enhancing neuronal electric activity, and contributing to neuroinflammation and oxidative stress
Publication date: Available online 3 March 2020Source: Progress in NeurobiologyAuthor(s): Ekaterina Kopeikina, Marina Dukhinova, Amanda W.Y. Yung, Tatyana Veremeyko, Inna S. Kuznetsova, Thomas Y.B. Lau, Kseniia Levchuk, Eugene D. Ponomarev (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - March 4, 2020 Category: Neuroscience Source Type: research
Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy
Publication date: Available online 24 February 2020Source: Progress in NeurobiologyAuthor(s): Seulgi Shin, Dohee Kim, Ji Yeon Song, Hyeanjeong Jeong, Seung Jae Hyeon, Neil W. Kowall, Hoon Ryu, Ae Nim Pae, Sungsu Lim, Yun Kyung Kim (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - February 25, 2020 Category: Neuroscience Source Type: research
The functional architecture, receptive field characteristics, and representation of objects in the visual network of the pigeon brain
Publication date: Available online 22 February 2020Source: Progress in NeurobiologyAuthor(s): William James Clark, Michael ColomboAbstractWe provide an extensive review of the pigeon visual system, focussing on the known cell types, receptive field characteristics, mechanisms of perception/visual attention, and projection profiles of neurons in the thalamofugal and tectofugal pathways. The similarities and differences with the primate visual system at each stage of the visual hierarchy are highlighted. We conclude with a discussion of object and face processing in birds, as well as the current state of knowledge in the sea...
Source: Progress in Neurobiology - February 23, 2020 Category: Neuroscience Source Type: research
Distinct roles of parvalbumin- and somatostatin-expressing neurons in flexible representation of task variables in the prefrontal cortex
Publication date: Available online 15 February 2020Source: Progress in NeurobiologyAuthor(s): Huijeong Jeong, Dohoung Kim, Min Song, Se-Bum Paik, Min Whan JungABSTRACTA hallmark of the prefrontal cortex (PFC) is flexible representation of task-relevant variables. To investigate roles of different interneuron subtypes in this process, we examined discharge characteristics and inactivation effects of parvalbumin (PV)- and somatostatin (SST)-expressing neurons in the mouse PFC during probabilistic classical conditioning. We found activity patterns and inactivation effects differed between PV and SST neurons: SST neurons conve...
Source: Progress in Neurobiology - February 16, 2020 Category: Neuroscience Source Type: research
Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson’s disease
Publication date: Available online 11 February 2020Source: Progress in NeurobiologyAuthor(s): Phillippa J Carling, Heather Mortiboys, Claire Green, Simeon Mihaylov, Cynthia Sandor, Aurelie Schwartzentruber, Rosie Taylor, Wenbin Wei, Chris Hastings, Siew Wong, Christine Lo, Samuel Evetts, Hannah Clemmens, Matthew Wyles, Sam Willcox, Thomas Payne, Rachel Hughes, Laura Ferraiuolo, Caleb Webber, Winston HideAbstractMechanistic disease stratification will be crucial to develop a precision medicine approach for future disease modifying therapy in sporadic Parkinson’s disease (sPD). Mitochondrial and lysosomal dysfunction are k...
Source: Progress in Neurobiology - February 13, 2020 Category: Neuroscience Source Type: research
Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation
Publication date: Available online 11 February 2020Source: Progress in NeurobiologyAuthor(s): Mahesh M. Karnani, Cornelia Schöne, Edward F. Bracey, J. Antonio González, Paulius Viskaitis, Han-Tao Li, Antoine Adamantidis, Denis BurdakovSummary<-- -->Appropriate motor control is critical for normal life, and requires hypothalamic hypocretin/orexin neurons (HONs). HONs are slowly regulated by nutrients, but also display rapid (subsecond) activity fluctuations in vivo. The necessity of these activity bursts for sensorimotor control and their roles in specific phases of movement are unknown. Here we show that temporally-r...
Source: Progress in Neurobiology - February 11, 2020 Category: Neuroscience Source Type: research
Editorial Board
Publication date: March 2020Source: Progress in Neurobiology, Volume 186Author(s): (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - February 11, 2020 Category: Neuroscience Source Type: research
Cysteine String Proteins
Publication date: Available online 7 February 2020Source: Progress in NeurobiologyAuthor(s): Cameron B. GundersenAbstractCysteine string protein (CSP) was discovered by use of a synapse-specific, monoclonal antibody to screen a cDNA expression library in Drosophila. A vertebrate CSP homolog was later identified and shown to co-purify with synaptic vesicles. CSP-α is now recognized as a membrane constituent of many regulated secretory organelles. Knockout of the csp gene in Drosophila produced temperature-sensitive paralysis reflecting a loss of evoked (but not spontaneous) transmitter release. However, CSP’s role in reg...
Source: Progress in Neurobiology - February 9, 2020 Category: Neuroscience Source Type: research
White matter structure and myelin-related gene expression alterations with experience in adult rats
In conclusion, macroscale measures of WM plasticity are supported by both molecular and cellular evidence and confirm that myelination is one of the underlying mechanisms. (Source: Progress in Neurobiology)
Source: Progress in Neurobiology - January 29, 2020 Category: Neuroscience Source Type: research
