Protein tyrosine phosphatase 1B inhibitory triterpene glycosides from Mussaenda pilosissima Valeton
Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Vu Kim Thu, Nguyen Xuan Bach, Nguyen Thi Thu Hien, Hua Thi Son, Tran Hong Quang, Youn-Chul Kim, Hyuncheol Oh, Phan Van KiemAbstractThree new triterpene glycosides, mussapilosides A–C (1-3) together with six known triterpene glycosides, cincholic acid-28-O-β-d-glucopyranosyl ester (4), mussaendoside S (5), quinovic acid 28-O-β-d-glucopyranosyl ester (6), glycoside A (7), glycoside B (8), and quinovic acid 3-O-β-d-glucopyranosyl(1→2)-β-d-glucopyranoside (9) were isolated from the leaves of Mussaenda pilosissima. Their chemical structures ...
Source: Phytochemistry Letters - February 21, 2020 Category: Chemistry Source Type: research
A-type doubly linked proanthocyanidin trimer and other metabolites from Canthium venosum fruits, and their biological activities
Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Appolinaire Kene Dongmo, Raymond Ngansop Nono, Fatma Kaaniche, Isabelle Kamga Mawabo, Marcel Frese, Jean Rodolphe Chouna, Celine Nguefeu Nkenfou, Bruno Ndjakou Lenta, David Ngnokam, Pépin Nkeng-Efouet-Alango, Norbert SewaldAbstractPhytochemical investigation of Canthium venosum fruits led to the isolation of a new doubly linked A-type proanthocyanidin trimer: epicatechin-(2β→O→7, 4β →8)-catechin-(5→O→2β, 6→4β)-epicatechin [venosumtannin A-1 (1)], along with twenty known compounds 2-21. Allyl (9a) and acetyl (9b) derivatives of ...
Source: Phytochemistry Letters - February 21, 2020 Category: Chemistry Source Type: research
Analysis of chemical composition of Inula japonica Thunb. extract and in vitro screening for anti-pulmonary fibrosis active components
In conclusion, chemical components of the extract from Inula japonica Thunb. might be potential agents for the treatment of IPF.Graphical abstract (Source: Phytochemistry Letters)
Source: Phytochemistry Letters - February 21, 2020 Category: Chemistry Source Type: research
New phenylethanoid from the flower of Osmanthus fragrans and their bioactivities on human dermal fibroblasts
In conclusion, we demonstrated that the aqueous extract of flower of O. fragrans contained phenylethanoid-rich constituents which revealed bioactivities at the cellular level of HDFs.Graphical abstract (Source: Phytochemistry Letters)
Source: Phytochemistry Letters - February 14, 2020 Category: Chemistry Source Type: research
New flavones from the stems of Dracaena angustifolia
Publication date: April 2020Source: Phytochemistry Letters, Volume 36Author(s): Ting Zhao, Xu-Hua Nong, Bin Zhang, Min-Min Tang, Dan-Yu Huang, Jia-Li Wang, Jun-Lu Xiao, Guang-Ying ChenAbstractFour new flavone derivatives (1–4), together with six known flavones (5-10), were isolated from the stems of Dracaena angustifolia. The complete structures of new compounds were elucidated by analyses of spectroscopic data and quantum chemistry calculations. Compounds 2, 9 and 10 displayed weak anti-inflammatory activity with IC50 values of 45, 33 and 61 μM, respectively.Graphical abstract (Source: Phytochemistry Letters)
Source: Phytochemistry Letters - February 13, 2020 Category: Chemistry Source Type: research
