Incontinentia Pigmenti with Persistent Hypercalcemia: Case Report
We report a case of persistent hypercalcemia (10.6–11.3 mg/dL) in a 19‐month‐old Caucasian boy with clinical IP. The proposed mechanism for his hypercalcemia is discussed. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 30, 2016 Category: Dermatology Authors: Jacob Adashek, Weiyi Mu, Jacquelyn Francis, Bernard Cohen, Cozumel Pruette, Annie Grossberg, Joann Bodurtha Tags: Case Report Source Type: research

Congenital Malalignment of the Great Toenails With Acute Paronychia
Abstract Congenital malalignment of the great toenails (CMGT) has been well documented. In the present case, it was complicated by acute paronychia. It is important for physicians to recognize and treat CMGT to prevent sequelae such as onychocryptosis, onychogryphosis, and recurrent paronychia. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 30, 2016 Category: Dermatology Authors: Shari R. Lipner, Richard K. Scher Tags: Brief Report Source Type: research

Is Gianotti –Crosti Syndrome Associated with Atopy? A Case–Control Study and a Postulation on the Intrinsic Host Factors in Gianotti–Crosti Syndrome
ConclusionGCS is significantly associated with AD and the presence of atopic conditions. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 23, 2016 Category: Dermatology Authors: Antonio Chuh, Vijay Zawar, Albert Lee, Gabriel Sciallis Tags: Original Article Source Type: research

Pediatric Erythema Annulare Centrifugum Treated with Oral Fluconazole: A Retrospective Series
ConclusionOral fluconazole was an effective treatment in five children with EAC. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 23, 2016 Category: Dermatology Authors: Lacey L. Kruse, Brandi M. Kenner‐Bell, Anthony J. Mancini Tags: Original Article Source Type: research

Vesicular Hand Dermatitis in a Child: Allergy to Methylisothiazolinone
Abstract A 7‐year‐old girl presented with a history of vesicular hand dermatitis that only partially improved with the use of steroids. Patch testing revealed a 1+ reaction to 0.2% aqueous methylisothiazolinone (MI) and 0.01% aqueous methylchloroisothazolinone/methylisothiazolinone (MCI/MI). Dyshidrosiform hand dermatitis is rare in children younger than 10 years of age, and this pattern has not been reported with MCI/MI allergy. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 23, 2016 Category: Dermatology Authors: Saira Khanna, Margo Reeder Tags: Brief Report Source Type: research

A Case of Blau Syndrome with NOD2 E383K Mutation
We report a 3.5‐year‐old Japanese boy who developed lichenoid papules and erythema with noncaseating epithelioid cell granulomas with a scant lymphocytic infiltrate histologically on his limbs at the age of 8 months. Genetic analysis of the patient and his parents, who had no medical past history, revealed heterozygous 1147G>A (E383K) mutation of NOD2 in the patient and in his father, so the patient was diagnosed with Blau syndrome and his father as an asymptomatic carrier. Although Blau syndrome has been reported as a genetic disease with high penetrance, asymptomatic carrier cases of a family with the same E383K m...
Source: Pediatric Dermatology - June 23, 2016 Category: Dermatology Authors: Jun Harada, Takeshi Nakajima, Nobuo Kanazawa Tags: Case Report Source Type: research

Is Gianotti–Crosti Syndrome Associated with Atopy? A Case–Control Study and a Postulation on the Intrinsic Host Factors in Gianotti–Crosti Syndrome
ConclusionGCS is significantly associated with AD and the presence of atopic conditions. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 23, 2016 Category: Dermatology Authors: Antonio Chuh, Vijay Zawar, Albert Lee, Gabriel Sciallis Tags: Original Article Source Type: research

A Rare Presentation of a Dermoid Cyst with Draining Sinus in a Child: Case Report and Literature Review
We report a rare case wherein a frontotemporal dermoid in a 21‐month‐old girl presented with a draining sinus tract to the skin and extended intracranially through the sphenoid bone. It was removed surgically and a dermoid cyst was removed from the frontotemporal region, extending superficially from the skin sinus tract through the sphenoid bone and attaching to the dura of the anterior temporal lobe. In addition to our case presentation, a literature review was performed to identify the few reported similar cases in the published literature, the combination of which suggests that frontotemporal dermoid cysts with asso...
Source: Pediatric Dermatology - June 13, 2016 Category: Dermatology Authors: Chen Yan, David W. Low Tags: Case Report Source Type: research

Late ‐Onset Nail Changes Associated with Hand, Foot, and Mouth Disease: A Clinical Analysis of 56 Cases
Abstract ObjectivesTo investigate the development and clinical characteristics of nail changes in hand, foot, and mouth disease (HFMD). MethodsA telephone survey was conducted with the parents of patients diagnosed with HFMD in the Fourth General Hospital of Nanhai from June to August 2013 to document nail changes within 3 months of diagnosis of HFMD. ResultsValid survey results were obtained from 273 cases. Definitive nail changes were identified in 56 patients (20.5%). More boys (25.8%) than girls (10.6%) (p 
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Dong ‐ling Long, Shi‐yuan Zhu, Cai‐zi Li, Cui‐yan Chen, Wan‐tao Du, Xi Wang Tags: Original Article Source Type: research

Prognosis and Management of Congenital Hair Shaft Disorders with Fragility —Part I
The objective was to review the literature regarding the prognosis and treatment options of hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in the English language related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, wooly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili annula...
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Gaurav Singh, Mariya Miteva Tags: Review Source Type: research

Prognosis and Management of Congenital Hair Shaft Disorders without Fragility —Part II
The objective of this study was to review the literature regarding the prognosis and treatment options for hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in English related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, woolly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili ann...
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Gaurav Singh, Mariya Miteva Tags: Review Source Type: research

Neurodevelopmental Outcomes in Children with PHACE Syndrome
ConclusionAlthough most children in this cohort of patients with PHACE syndrome did not have significant neurodevelopmental deficits, a subset of patients had delays in multiple areas. Practitioners who work with these children should routinely ask about neurocognitive and developmental skills. Children with more severe phenotypes should be referred for appropriate evaluations and intervention services. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Cheryl L. Brosig, Dawn H. Siegel, Anita N. Haggstrom, Ilona J. Frieden, Beth A. Drolet Tags: Original Article Source Type: research

Risk Factors for Premature Hair Graying in Young Turkish Adults
ConclusionPHG is closely related to factors causing oxidative stress, such as emotional stress, alcohol consumption, and chronic diseases in genetically predisposed men and women. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Asli Akin Belli, Fatma Etgu, Seyran Ozbas Gok, Bilge Kara, Gursoy Dogan Tags: Original Article Source Type: research

Late‐Onset Nail Changes Associated with Hand, Foot, and Mouth Disease: A Clinical Analysis of 56 Cases
Abstract ObjectivesTo investigate the development and clinical characteristics of nail changes in hand, foot, and mouth disease (HFMD). MethodsA telephone survey was conducted with the parents of patients diagnosed with HFMD in the Fourth General Hospital of Nanhai from June to August 2013 to document nail changes within 3 months of diagnosis of HFMD. ResultsValid survey results were obtained from 273 cases. Definitive nail changes were identified in 56 patients (20.5%). More boys (25.8%) than girls (10.6%) (p 
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Dong‐ling Long, Shi‐yuan Zhu, Cai‐zi Li, Cui‐yan Chen, Wan‐tao Du, Xi Wang Tags: Original Article Source Type: research

Prognosis and Management of Congenital Hair Shaft Disorders with Fragility—Part I
The objective was to review the literature regarding the prognosis and treatment options of hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in the English language related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, wooly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili annula...
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Gaurav Singh, Mariya Miteva Tags: Review Source Type: research

Prognosis and Management of Congenital Hair Shaft Disorders without Fragility—Part II
The objective of this study was to review the literature regarding the prognosis and treatment options for hair shaft disorders. We used keywords in the search engines PubMed and Medline to identify all publications in English related to the prognosis and management of hair shaft disorders. Data were extracted from 96 articles that met search criteria. Findings were limited to case reports and small case series, as no studies were found. Disorders that improve in childhood include pili torti, trichorrhexis invaginata, woolly hair, and pili trianguli et canaliculi. Others, such as trichorrhexis nodosa, monilethrix, pili ann...
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Gaurav Singh, Mariya Miteva Tags: Review Source Type: research

Ultrasound Diagnosis and Staging in Pediatric Hidradenitis Suppurativa
In conclusion, ultrasound can be a reliable and safe imaging tool to support diagnosis and staging and may help in the noninvasive monitoring of treatment in children. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 12, 2016 Category: Dermatology Authors: Ximena Wortsman, Carolyn Rodriguez, Carolina Lobos, Gonzalo Eguiguren, Maria Teresa Molina Tags: Brief Report Source Type: research

Koebner's Phenomenon in Childhood Henoch ‐Schönlein Purpura: A Report of Two Cases
We report two children with HSP who developed Koebner's phenomenon on the second day after the onset of rash. The first was an 11‐year‐old girl with rheumatic heart disease who presented with abdominal pain for 1 month and subsequently developed rash and nephritis. The second patient was a 7‐year‐old girl who presented with rash and polyarthritis. To the best of our knowledge, Koebner's phenomenon in childhood HSP has not been reported. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Shreya Sharma, Venkatesh Chandrasekaran, Sriram Krishnamurthy, Suresh Mekala, Subramanian Mahadevan Tags: Case Report Source Type: research

Verrucous Penile Plaque in an 11 ‐Year‐Old Boy
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Anisha Sethi, Sunil Kumar Gupta, Gurpoonam Jatana Tags: Photoquiz Source Type: research

Multifocal Lymphangioendotheliomatosis with Thrombocytopenia: Presentation of Two Cases Treated with Sirolimus
We present two cases of MLT treated with sirolimus. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Agustina Lanöel, Adriana Natalia Torres Huamani, Aurora Feliú, María Josefina Sala, Mariana Alvarez, Andrea Bettina Cervini Tags: Case Report Source Type: research

Congenital Milia En Plaque
Abstract Milia en plaque is a rare, benign, localized, entity typically seen in adults after the third decade of life. Although there have been a few cases described in children, we describe the first case in a newborn. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Annie R. Wang, Lionel Bercovitch Tags: Brief Report Source Type: research

Koebner's Phenomenon in Childhood Henoch‐Schönlein Purpura: A Report of Two Cases
We report two children with HSP who developed Koebner's phenomenon on the second day after the onset of rash. The first was an 11‐year‐old girl with rheumatic heart disease who presented with abdominal pain for 1 month and subsequently developed rash and nephritis. The second patient was a 7‐year‐old girl who presented with rash and polyarthritis. To the best of our knowledge, Koebner's phenomenon in childhood HSP has not been reported. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Shreya Sharma, Venkatesh Chandrasekaran, Sriram Krishnamurthy, Suresh Mekala, Subramanian Mahadevan Tags: Case Report Source Type: research

A Report of Two Patients with Darier Disease and Hidradenitis Suppurativa
We report two unique cases of patients with Darier disease and hidradenitis suppurativa. Although it is unknown whether there is a connection between the two diseases, it is possible that an interaction between sarcoendoplasmic reticulum calcium transport ATPase and Notch homolog 1, translocation‐associated (Drosophila) caused both diseases in these individuals. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Jennifer Ornelas, Raja Sivamani, Smita Awasthi Tags: Brief Report Source Type: research

Successful Treatment of Keratosis Pilaris Rubra with Pulsed Dye Laser
ConclusionsPDL is an effective, easily accessible, and underused therapy in the treatment of keratosis pilaris rubra. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 9, 2016 Category: Dermatology Authors: Jennifer J. Schoch, Megha M. Tollefson, Patricia Witman, Dawn M.R. Davis Tags: Original Article Source Type: research

Brimonidine Toxicity Secondary to Topical Use for an Ulcerated Hemangioma
We report the case of a 2‐month‐old girl who developed life‐threatening brimonidine toxicity requiring intubation and mechanical ventilation secondary to central nervous system depression and apnea after topical application to an ulcerated IH. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - June 8, 2016 Category: Dermatology Authors: Kamalvir Gill, Cheryl Bayart, Ritu Desai, Alex Golden, Patricia Raimer, Joan Tamburro Tags: Case Report Source Type: research

Myelodysplastic Syndrome Occurring in a Patient with Gorlin Syndrome
We report a case of myelodysplastic syndrome (MDS) occurring in an African American boy with Gorlin syndrome with a novel PTCH1 mutation. Before developing MDS, the patient had been treated with chemotherapy and radiation for a medulloblastoma. He received a bone marrow transplant for the MDS and eventually died of treatment complications. Secondary hematologic malignancies are a known complication of certain chemotherapeutics, although whether a patient with Gorlin syndrome has a greater propensity for the development of such malignancies is unclear. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 30, 2016 Category: Dermatology Authors: Jamie L. Mull, Lisa M. Madden, Susan J. Bayliss Tags: Brief Report Source Type: research

Neonatal Alopecia Due to Birth Trauma: Case Report and Trichoscopic Findings
Abstract A 4‐day‐old boy was referred for evaluation of an oval patch of occipital alopecia associated with caput succedaneum and ipsilateral eyelid ecchymoses. Based on the history of a prolonged, difficult labor with vacuum‐assisted delivery, the diagnosis of neonatal alopecia associated with birth trauma was made. Trichoscopy showed purple dots corresponding to blood extravasation and follicular ostia. We also review the trichoscopic differential diagnosis of focal neonatal alopecia. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 30, 2016 Category: Dermatology Authors: Giulia Liberati, Michela Starace, Annalisa Patrizi, Bianca Maria Piraccini Tags: Brief Report Source Type: research

Mucocutaneous Findings in 100 Children with Down Syndrome
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Tags: Erratum Source Type: research

Pediatric Skin of ColorNanette B. Silverberg, Carola Durán‐McKinster, Yong‐Kwang Tay, eds., Pediatric Skin of Color, New York: Springer, 2015, ISBN 978‐1‐4614‐6654‐3
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: John C. Browning Tags: Book Review Source Type: research

Medallion‐Like Dermal Dendrocytic Hamartoma, Dermatofibrosarcoma Protuberans, and Adenosine Deaminase–Deficient Severe Combined Immunodeficiency
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Edward W. Cowen, Dominique C. Pichard, Elizabeth Garabedian, Markku Miettinen Tags: Correspondence Source Type: research

Varicella within a Prior Immunization Reaction Site: Another Example of “Isovaccinetopic Response”
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Stefano Caccavale, Tobia Caccavale, Maddalena La Montagna Tags: Correspondence Source Type: research

Enlarging Neck Mass in an Adolescent Boy
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Samantha C. Gordon, Swati Mehrotra, Lily C. Uihlein Tags: Photoquiz Source Type: research

Unilateral Petechial and Pigmentary Macules in a 12‐Year‐Old Boy
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Thomas King, Pick‐Ngor Woo, Antonia Barbieri Tags: Photoquiz Source Type: research

Ulcerated Skin Nodule on the Chest
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Ahu Kara, Nuri Bayram, Malik Ergin, Ilker Devrim Tags: Photoquiz Source Type: research

An Infant with a Lump on the Earlobe
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Dirk Van Gysel, Hendrik De Raeve, Bruno Bruylants Tags: Photoquiz Source Type: research

A Symmetrical Flexural Rash
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Authors: Viviana Lora, Bruno Capitanio, Carlo Cota Tags: Photoquiz Source Type: research

Patient Perspectives: The importance of sun protection
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Tags: Patient Perspectives Source Type: research

Issue Information ‐ Table of Contents
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Tags: Issue Information Source Type: research

Issue Information ‐ Editorial Board
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - May 12, 2016 Category: Dermatology Tags: Issue Information Source Type: research

Longitudinal Antibiotic Susceptibility Profiles of Staphylococcus aureus Cutaneous Infections in a Pediatric Outpatient Population
Abstract This longitudinal update on Staphylococcus aureus prevalence and antibiotic resistance patterns surveyd 291 cultures from 188 patients in a pediatric outpatient dermatology clinic with suspected skin and soft tissue infections. The prevalence of methicillin‐resistant Staphylococcus aureus remained stable at 24%. Staphylococcus aureus resistance to tetracyclines modestly but demonstrably increased in the interval since 2009. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Nathaniel A. Slater, Peter H. Gilligan, Dean S. Morrell Tags: Brief Report Source Type: research

Radiation Recall Dermatitis Secondary to Dactinomycin
We report the case of a 15‐month‐old boy with RRD to dactinomycin. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Brea Prindaville, Kimberly A. Horii, Kristi M. Canty Tags: Brief Report Source Type: research

Bullous Kaposiform Hemangioendothelioma Masquerading as Aplasia Cutis Congenita
We present the case of a male infant with violaceous bullae on the scalp that were initially thought to be bullous aplasia cutis but at 3 months of age were diagnosed as a kaposiform hemangioendothelioma. This diagnosis should be considered when evaluating newborns with bullous plaques on the scalp that do not heal in the first 2–3 weeks of life. Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that typically presents as a violaceous to purpuric plaque at birth or early infancy. It may be associated with Kasabach‐Merritt phenomenon (KMP), a potentially life‐threatening consumptive coagulopathy. (Sou...
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Aaron J. Steen, Joseph H. Shin, Nicole C. Pace, Mark Edgar, Michael R. Clay, Konstantinos Linos, Dorothea T. Barton, Julianne A. Mann Tags: Brief Report Source Type: research

Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation
We present the first case of FCTN with multiple agminated lesions on the leg of an infant and the difficulties encountered in the differential diagnosis with dermatofibrosarcoma protuberans. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Camila Downey, Luis Requena, Silvia Bagué, Miquel Ángel Sánchez Martínez, Josep Lloreta, Eulalia Baselga Tags: Case Report Source Type: research

Atypical Forms of Hand, Foot, and Mouth Disease: A Prospective Study of 47 Italian Children
ConclusionOur prospective study allowed the identification of three HFMD phenotypes differing from the classical form. Clinical care of these patients should include symptomatic treatment of extracutaneous features and, if necessary, hospitalization for complications. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Iria Neri, Arianna Dondi, Andreas Wollenberg, Lorenza Ricci, Giampaolo Ricci, Giulia Piccirilli, Tiziana Lazzarotto, Annalisa Patrizi Tags: Original Article Source Type: research

Verrucous Penile Plaque in an 11‐Year‐Old Boy
(Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Anisha Sethi, Sunil Kumar Gupta, Gurpoonam Jatana Tags: Photoquiz Source Type: research

Study of the Atopic March: Development of Atopic Comorbidities
ConclusionsThis longitudinal observation of infants with AD provides evidence of the atopic march. Pimecrolimus was safe and effective in infants with mild to moderate AD. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Lynda Schneider, Jon Hanifin, Mark Boguniewicz, Lawrence F. Eichenfield, Jonathan M. Spergel, Rada Dakovic, Amy S. Paller Tags: Original Article Source Type: research

Adverse Events in Young and Preterm Infants Receiving Topical Timolol for Infantile Hemangioma
ConclusionIn this cohort of at‐risk infants, topical timolol appeared to provide safe treatment for IHs in full‐term infants receiving a dose of less than 0.2 mg/kg/day, but infants with a PMA of less than 44 weeks and weight at treatment initiation of less than 2,500 g may be at risk of adverse events, including bradycardia, hypotension, apnea, and hypothermia. We recommend close monitoring of temperature, blood pressure, and heart rate in premature and low‐birthweight infants with IHs at initiation of and during therapy with topical timolol. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Peter Frommelt, Anna Juern, Dawn Siegel, Kristen Holland, Marcia Seefeldt, JiaDe Yu, Michael Uhing, Kelly Wade, Beth Drolet Tags: Original Article Source Type: research

Contact Sensitization in Children: A Retrospective Study of 2,614 Children from a Single Center
The objective was to evaluate contact sensitization in children with suspected contact dermatitis, the relationship with atopic dermatitis (AD), and the most common allergens. MethodsThe same team patch tested 2,614 children younger than 11 years old with a standard series of 30 allergens. ResultsA total of 1220 children (46.7%) developed at least one positive reaction, 606 of which were clinically relevant (49.7%). The most frequent reactions were to nickel sulfate (22.7%), cobalt chloride (11.1%), potassium dichromate (9.9%), neomycin sulfate (5.2%), thimerosal (4.2%), cocamidopropyl betaine (3.4%), and methylchloroisoth...
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Anna Belloni Fortina, Elena Fontana, Andrea Peserico Tags: Original Article Source Type: research

Crisaborole Topical Ointment, 2% in Patients Ages 2 to 17 Years with Atopic Dermatitis: A Phase 1b, Open‐Label, Maximal‐Use Systemic Exposure Study
ConclusionsThis open‐label study provides evidence that crisaborole topical ointment, 2% was well tolerated, with limited systemic exposure under maximal‐use conditions in patients ages 2 years and older. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Lee T. Zane, Leon Kircik, Robert Call, Eduardo Tschen, Zoe Diana Draelos, Sanjay Chanda, Merrie Van Syoc, Adelaide A. Hebert Tags: Original Article Source Type: research

Benign Nerve Sheath Myxoma in an Infant Misdiagnosed as Infantile Digital Fibromatosis
We present this case to emphasize that nerve sheath myxomas (also known as myxoid neurothekeoma) should be included in the differential diagnosis of dermal nodules in infants. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 30, 2016 Category: Dermatology Authors: Şule Güngör, Servet Şişman, Emek Kocaturk, Ilteris Oguz Topal, Selda Yıldırım Tags: Brief Report Source Type: research