Eliminating bias and accelerating the clinical translation of oral microbiome research in oral oncology
Dear Sirs, (Source: Oral Oncology)
Source: Oral Oncology - March 1, 2018 Category: Cancer & Oncology Authors: Rohit Kunnath Menon, Divya Gopinath Tags: Letter to the editor Source Type: research

RETRACTED: Systemic therapy in the management of metastatic or advanced salivary gland cancers
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). (Source: Oral Oncology)
Source: Oral Oncology - February 28, 2018 Category: Cancer & Oncology Authors: Aymen Lagha, Nesrine Chraiet, Mouna Ayadi, Sarra Krimi, Bassem Allani, Hela Rifi, Henda Raies, Amel Mezlini Source Type: research

Editorial Board/Aims & Scope
(Source: Oral Oncology)
Source: Oral Oncology - February 28, 2018 Category: Cancer & Oncology Source Type: research

Are oral mucosal nevi potential precursors for oral mucosal melanoma?
The origin of oral mucosal melanoma remains controversial with oral mucosal nevi being hypothesized to be a possible precursor. The hypotheses can be supported by the characteristics shared by the nevus cells and the melanoma cells including spindle-shaped, lack of dendritic processes, lack of contact inhibition and inability to transfer the melanosomes to the keratinocytes [1]. (Source: Oral Oncology)
Source: Oral Oncology - February 28, 2018 Category: Cancer & Oncology Authors: A. Thirumal Raj, Shankargouda Patil, Chandini Rajkumar Tags: Letter to the editor Source Type: research

Primary synovial sarcoma (SS) of larynx: An unusual site
Soft tissue sarcomas (STSs) are heterogeneous disorders comprises myriad subtypes originated from mesenchymal stem cells. Synovial sarcomas (SSs) are belligerent malignant tumours included in this group affecting extremities of patients ’ age ranging between 15 and 35 years. SS taking place in head and neck region is rare event and primary laryngeal involvement is even rarer happening. There are 20 odd published cases documented in world literature so far. Here we are presenting primary laryngeal SS occurred in 31 year old ma le patient initially mimicking laryngeal carcinoma as patient was chronic smoker and classic...
Source: Oral Oncology - February 26, 2018 Category: Cancer & Oncology Authors: Irappa Madabhavi, Vishalkumar Bhardawa, Mitul Modi, Apurva Patel, Malay Sarkar Tags: Letter to the editor Source Type: research

Locoregional extension and patterns of failure for nasopharyngeal carcinoma with intracranial extension
IMRT has been accepted as the standard treatment technique of nasopharyngeal carcinoma (NPC) [1]. Clinical target volume (CTV) delineation is the key point in local tumor control and normal tissue protection. Although the CTV definitions are different in different centers, the 5-year local recurrence-free survival (LFFS) for NPC after IMRT is about 90% and the late toxicities are well tolerable [2 –4]. However, radiotherapy of NPC with intracranial extension is technically challenging. In the study of 70 patients with T4 classification NPC after IMRT, 16 patients developed local failure, the images of 2 patients with onl...
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Caineng Cao, Feng Jiang, Qifeng Jin, Ting Jin, Shuang Huang, Qiaoying Hu, Yuanyuan Chen, Yongfeng Piao, Yonghong Hua, Xinglai Feng, Xiaozhong Chen Source Type: research

Cause-specific mortality in patients with head and neck cancer: Long-term follow-up of a population-based cohort from 1986 to 2012 accounting for competing risks
Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with approximately 630,000 annual cases diagnosed worldwide [1]. Despite the declining prevalence of smoking, the incidence of HNSCC is increasing [2], although the 5-year relative survival rate has improved somewhat through a changing etiology coupled with a rise in human papillomavirus (HPV)-associated disease and advances in treatment [3,4]. (Source: Oral Oncology)
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Janne A. V äisänen, Olli-Pekka Alho, Petri T. Koivunen, Esa Läärä Source Type: research

Optimizing the induction chemotherapy regimen for patients with locoregionally advanced nasopharyngeal Carcinoma: A big-data intelligence platform-based analysis
This study aimed at identifying the optimal induction chemotherapy regimen for patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated by intensity-modulated radiotherapy. (Source: Oral Oncology)
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Hao Peng, Ling-Long Tang, Bin-Bin Chen, Lei Chen, Wen-Fei Li, Yan-Ping Mao, Xu Liu, Yuan Zhang, Li-Zhi Liu, Li Tian, Ying Guo, Ying Sun, Jun Ma Source Type: research

The impact of HPV status on weight loss and feeding tube use in oropharyngeal carcinoma
Patients with oropharyngeal carcinoma (OPC) are at nutritional risk due to the effects of the tumour itself and the toxicities of the treatment modalities used [1 –3]. It has been well established that malnutrition and weight loss is common in head and neck cancer (HNC), and critical weight loss (CWL) (defined as ≥5% loss in one month [4,5]), has been shown to affect outcomes and survival [6–8]. The epidemiology of OPC has changed in the last decade wit h the increasing incidence of human papillomavirus (HPV)-associated disease [9]. (Source: Oral Oncology)
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Belinda Vangelov, Damian P. Kotevski, Janet R. Williams, Robert I. Smee Source Type: research

Tumor volume as a predictor of survival in T3 glottic carcinoma: A novel approach to patient selection
Advanced laryngeal cancer will affect over 4000 Americans this year [1]. Critical functions of breathing, swallowing and speech may be decimated by the disease if not by our treatments for the disease. Thus, modern head and neck cancer care strives to achieve a delicate balance between maximizing survival, functional outcomes and quality of life. (Source: Oral Oncology)
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Peter T. Dziegielewski, William J. Reschly, Chris G. Morris, Reordan Danny DeJesus, Natalie Silver, Brian J. Boyce, Inocente Santiago, Robert J. Amdur, William M. Mendenhall Source Type: research

Locoregional extension and patterns of failure for nasopharyngeal carcinoma with intracranial extension
IMRT has been accepted as the standard treatment technique of nasopharyngeal carcinoma (NPC) [1]. Clinical target volume (CTV) delineation is the key point in local tumor control and normal tissue protection. Although the CTV definitions are different in different centers, the 5-year local recurrence-free survival (LFFS) for NPC after IMRT is about 90% and the late toxicities are well tolerable [2 –4]. However, radiotherapy of NPC with intracranial extension is technically challenging. In the study of 70 patients with T4 classification NPC after IMRT, 16 patients developed local failure, the images of 2 patients with onl...
Source: Oral Oncology - February 20, 2018 Category: Cancer & Oncology Authors: Caineng Cao, Feng Jiang, Qifeng Jin, Ting Jin, Shuang Huang, Qiaoying Hu, Yuanyuan Chen, Yongfeng Piao, Yonghong Hua, Xinglai Feng, Xiaozhong Chen Source Type: research