Comparison of the Rotational Stability of Two Toric Intraocular Lenses in 1273 Consecutive Eyes
To compare the rotational stability of the 2 most commonly used toric intraocular lenses (TIOLs). (Source: Ophthalmology)
Source: Ophthalmology - March 12, 2018 Category: Opthalmology Authors: Bryan S. Lee, David F. Chang Source Type: research

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti –Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
To assess systemic vascular endothelial growth factor (VEGF)-A levels after treatment with intravitreous aflibercept, bevacizumab, or ranibizumab. (Source: Ophthalmology)
Source: Ophthalmology - March 7, 2018 Category: Opthalmology Authors: Lee M. Jampol, Adam R. Glassman, Danni Liu, Lloyd Paul Aiello, Neil M. Bressler, Elia J. Duh, Susan Quaggin, John A. Wells, Charles C. Wykoff, Diabetic Retinopathy Clinical Research Network Source Type: research

Visual and Refractive Outcomes in Manual versus Femtosecond Laser –Assisted Cataract Surgery
This study compares postoperative refractive and visual outcomes in eyes receiving MCS or FLACS. (Source: Ophthalmology)
Source: Ophthalmology - March 6, 2018 Category: Opthalmology Authors: Thomas A. Berk, Matthew B. Schlenker, Xavier Campos-M öller, Austin M. Pereira, Iqbal Ike K. Ahmed Source Type: research

Efficacy of a Deep Learning System for Detecting Glaucomatous Optic Neuropathy Based on Color Fundus Photographs
To assess the performance of a deep learning algorithm for detecting referable glaucomatous optic neuropathy (GON) based on color fundus photographs. (Source: Ophthalmology)
Source: Ophthalmology - March 2, 2018 Category: Opthalmology Authors: Zhixi Li, Yifan He, Stuart Keel, Wei Meng, Robert T. Chang, Mingguang He Source Type: research

A Randomized Trial of a Short 34-Gauge Needle for Intravitreal Injections
Intravitreal injections of anti –vascular endothelial growth factor agents have achieved excellent results1,2 and have become one of the most frequently performed intraocular procedures. Although intravitreal drug delivery of anti–vascular endothelial growth factor agents is effective, patients often report discomfort during t he procedure. A literature review in a previous study of the use of a 33-gauge needle for intravitreal injections3 indicated that there is no consensus regarding the effect of the intravitreal needle size and perceived pain. (Source: Ophthalmology)
Source: Ophthalmology - February 28, 2018 Category: Opthalmology Authors: Hirofumi Sasajima, Kotaro Tsuboi, Hikari Ono, Kenta Murotani, Motohiro Kamei Tags: Reports Source Type: research

Clinical Predictors of Regression of Choroidal Melanomas after Brachytherapy
To build multivariate models to assess correctly and efficiently the contribution of tumor characteristics on the rate of regression of choroidal melanomas after brachytherapy in a way that adjusts for confounding and takes into account variation in tumor regression patterns. (Source: Ophthalmology)
Source: Ophthalmology - February 27, 2018 Category: Opthalmology Authors: Mamunur Rashid, Jorma Heikkonen, Arun D. Singh, Tero T. Kivel ä Source Type: research

Choroidal Microvasculature Dropout Is Associated with Progressive Retinal Nerve Fiber Layer Thinning in Glaucoma with Disc Hemorrhage
We used OCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature dropout (MvD) in glaucomatous eyes with or without disc hemorrhage (DH), and the association with changes in retinal nerve fiber layer (RNFL) thickness. (Source: Ophthalmology)
Source: Ophthalmology - February 24, 2018 Category: Opthalmology Authors: Hae-Young Lopilly Park, Jin Woo Kim, Chan Kee Park Source Type: research

Laser Peripheral Iridotomy in Primary Angle Closure
To examine the efficacy and complications of laser peripheral iridotomy (LPI) in subjects with primary angle closure (PAC). (Source: Ophthalmology)
Source: Ophthalmology - February 23, 2018 Category: Opthalmology Authors: Sunita Radhakrishnan, Philip P. Chen, Anna K. Junk, Kouros Nouri-Mahdavi, Teresa C. Chen Tags: Ophthalmic Technology Assessment Source Type: research

Vision-Related Quality of Life Associated with Unilateral and Bilateral Ocular Conditions
To present ophthalmic patient time-tradeoff vision utilities for quantifying vision-related quality-of-life when the fellow eye still has good vision. These utilities are important for performing reliable cost-utility analyses. (Source: Ophthalmology)
Source: Ophthalmology - February 21, 2018 Category: Opthalmology Authors: Gary C. Brown, Melissa M. Brown, Joshua D. Stein, William E. Smiddy, Ophthalmic Utility Research Study Group Source Type: research

Characterizing Anterior Segment OCT Angle Landmarks of the Trabecular Meshwork Complex
To identify the presence or absence of 3 identifiable landmarks: trabecular meshwork (TM), Schlemm's canal (SC), and a novel landmark termed the band of extracanalicular limbal lamina (BELL), which is a landmark adjacent to SC visible on anterior segment (AS) OCT. These landmarks also were analyzed pathologically to identify all 3 landmarks. (Source: Ophthalmology)
Source: Ophthalmology - February 21, 2018 Category: Opthalmology Authors: Eric L. Crowell, Laura Baker, Alice Z. Chuang, Robert M. Feldman, Nicholas P. Bell, Patricia Ch évez-Barrios, Lauren S. Blieden Source Type: research

Macular Atrophy in the HARBOR Study for Neovascular Age-Related Macular Degeneration
To evaluate macular atrophy (MA) presence in the 24-month HARBOR study (NCT00891735) for neovascular age-related macular degeneration (AMD). (Source: Ophthalmology)
Source: Ophthalmology - February 21, 2018 Category: Opthalmology Authors: SriniVas R. Sadda, Lisa L. Tuomi, Beiying Ding, Anne E. Fung, J. Jill Hopkins Source Type: research

Endophthalmitis after Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors
We describe the presentation of patients developing endophthalmitis after intravitreal injection with vascular endothelial growth factor (VEGF) inhibitors. Moreover, we evaluate the management by comparing the outcomes of immediate tap and injection of intravitreal antibiotics (TAI) versus initial surgical pars plana vitrectomy (PPV). Finally, we analyze the predictive factors of visual outcomes at 6-month follow-up. (Source: Ophthalmology)
Source: Ophthalmology - February 21, 2018 Category: Opthalmology Authors: Kunyong Xu, Eric K. Chin, Steven R. Bennett, David F. Williams, Edwin H. Ryan, Sundeep Dev, Robert A. Mittra, Polly A. Quiram, John B. Davies, D. Wilkin Parke, Jill B. Johnson, Herbert L. Cantrill, David R.P. Almeida Source Type: research

Treatment Outcomes in the Primary Tube Versus Trabeculectomy Study after 1 Year of Follow-up
To report 1-year treatment outcomes in the Primary Tube Versus Trabeculectomy (PTVT) Study. (Source: Ophthalmology)
Source: Ophthalmology - February 21, 2018 Category: Opthalmology Authors: Steven J. Gedde, William J. Feuer, Wei Shi, Kin Sheng Lim, Keith Barton, Saurabh Goyal, Iqbal I.K. Ahmed, James Brandt, Primary Tube Versus Trabeculectomy Study Group Source Type: research

Re: Shantha et  al.: Ophthalmic manifestations and causes of vision impairment in Ebola virus disease survivors in Monrovia, Liberia (Ophthalmology. 2017;124:170-177)
We read with interest the study by Shantha et  al1 on the ophthalmic manifestations and causes of visual impairment in Ebola virus disease survivors in Monrovia. Our recent case-control study has provided additional information to help assist in the interpretation of the lesion attributed to Ebola seen in the fundus photograph (Fig 3 in their paper). The lesion they reported as a “chorioretinal scar with characteristic hyperpigmented scars with hypopigmented halo” was also present in 14.6% of our Ebola cohort, as well as 16.2% of our control population, suggesting an alternative etiology common in West Africa, such as...
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Paul J. Steptoe, Janet T. Scott, Foday Sahr, Matthew Vandy, Simon P. Harding, Nicholas A.V. Beare, Malcolm G. Semple Tags: Correspondence Source Type: research

Using Local Therapy to Control Noninfectious Uveitis
Treating uveitis aims to prevent the development of ocular structural changes related to intraocular inflammation that otherwise could lead to vision loss. Inflammation control is achieved with immunosuppressive drugs, primarily corticosteroids, and for many years has relied on these, particularly in cases with concomitant systemic diseases or bilateral uveitis.1 Although these drugs are effective in controlling the  inflammation, many patients do not have systemic involvement and are not keen to undertake systemic treatment. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Lazha Ahmed Talat Sharief, Sue Lightman, Oren Tomkins-Netzer Tags: Editorial Source Type: research