Open Cardiovascular Medicine Journal 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth.
Authors: Hussain A, Suleiman MS, George SJ, Loubani M, Morice A
Abstract
Hypoxic Pulmonary vasoconstriction (HPV) describes the physiological adaptive process of lungs to preserves systemic oxygenation. It has clinical implications in the development of pulmonary hypertension which impacts on outcomes of patients undergoing cardiothoracic surgery. This review examines both acute and chronic hypoxic vasoconstriction focusing on the distinct clinical implications and highlights the role of calcium and mitochondria in acute versus the role of reactive oxygen species and Rho GTPases in chronic HPV. Furthermore...
Source: Open Cardiovascular Medicine Journal - February 23, 2017 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Risk of Cerebral Embolization with Caseous Calcification of the Mitral Annulus: Review Article.
CONCLUSION: Based on our review, it would be reasonable to consider elective surgical resection of CCMA in asymptomatic patients who are good surgical candidates, because patients with CCMA may be at increased risk of embolic strokes, which are unrelated to AF.
PMID: 27990181 [PubMed - in process] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - December 21, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Effect of ATP-binding Cassette Transporter A1 (ABCA1) Gene Polymorphisms on Plasma Lipid Variables and Common Demographic Parameters in Greek Nurses.
CONCLUSION: Findings suggested that only R1587K polymorphism of ABCA1 gene was associated with lipid variables, age, and gender of Greek nurses. These findings may be helpful in assessing the risk factors for premature coronary heart disease and distinct individuals with lower/higher atherosclerotic burden.
PMID: 27990182 [PubMed - in process] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - December 21, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Correlation between Diastolic Function and Endothelial Function in Patients with Type 2 Diabetes and Hypertension.
CONCLUSION: The endothelial function assessed by FMD was worse in hypertensive diabetic patients with diastolic dysfunction. There were correlations between the diastolic function indexes and the endothelial function indexes in our sample.
PMID: 27867429 [PubMed - in process] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - November 22, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Insights in Hypothesis Testing and Making Decisions in Biomedical Research.
Authors: Sacha V, Panagiotakos DB
Abstract
It is a fact that p values are commonly used for inference in biomedical and other social fields of research. Unfortunately, the role of p value is very often misused and misinterpreted; that is why it has been recommended the use of resampling methods, like the bootstrap method, to calculate the confidence interval, which provides more robust results for inference than does p value. In this review a discussion is made about the use of p values through hypothesis testing and its alternatives using resampling methods to develop confidence intervals of the tested st...
Source: Open Cardiovascular Medicine Journal - October 14, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Life-threatening Rupture of a Femoral Pseudoaneurysm after Cardiac Catheterization.
Authors: Petrou E, Malakos I, Kampanarou S, Doulas N, Voudris V
Abstract
A pseudoaneurysm refers to a defect in the arterial wall, allowing communication of arterial blood with the adjacent extra-luminal space. Pseudoaneurysms result from traumatic arterial injury. With the increasing utilization of percutaneous arterial interventions, iatrogenic arterial injury has become the predominant cause of pseudoaneurysm formation. Rupture of the pseudoaneurysm comprises a vascular emergency. Clinical suspicion and imaging techniques are the cornerstones of timely diagnosis and appropriate management of the conditi...
Source: Open Cardiovascular Medicine Journal - October 14, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Chest Pain of Uncertain Aetiology: Role of Contrast Enhanced Computed Tomography in the Emergency Department.
We report a case where non ECG gated contrast enhanced CT in the emergency department for rule-out of pulmonary embolus guided to the actual diagnosis, which was, acute coronary event, as evidenced by the presence of perfusion defect.
PMID: 27733870 [PubMed - in process] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - October 14, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
The Current Indication for Pacemaker in Patients with Cardioinhibitory Vasovagal Syncope.
Authors: da Silva RM
Abstract
The most frequent cause of syncope is vasovagal reflex. It is associated with worse quality of life, depression, fatigue and physical injury. Recurrence of vasovagal syncope is an aggravating, reaching the rate of 69%. Initial step and pharmacological treatment may not work, especially in patients with recurrent syncope without prodrome. These patients can present cardioinhibitory response with asystole. Studies were designed to analyses the effectiveness of pacemaker for prevention of syncope. In this review, nonrandomized clinical trials, open-label randomized, double-blind ...
Source: Open Cardiovascular Medicine Journal - September 22, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Pulse Wave Analysis by Applanation Tonometry for the Measurement of Arterial Stiffness.
In conclusion, PWA is strongly correlated with PWV as a method for the evaluation of arterial stiffness.
PMID: 27651842 [PubMed - as supplied by publisher] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - September 22, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Heparin Versus Bivalirudin in Acute Myocardial Infarction: Unfractionated Heparin Monotherapy Elevated to Primary Treatment in Contemporary Percutaneous Coronary Intervention.
Authors: Centurión OA
Abstract
Bivalirudin, a direct thrombin inhibitor, was developed as an antithrombin agent for patients undergoing percutaneous coronary interventions (PCI) with the hypothesis that it would reduce bleeding complications without compromising the rate of ischemic events compared to heparin plus GP IIb/IIIa inhibitors. Although the cumulative evidence makes a strong argument for the use of bivalirudin rather than heparin plus systematic GP IIb/IIIa inhibitors for the great majority of patients with acute myocardial infarction (AMI) undergoing PCI, the benefit observed with bivalirudin w...
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
The Effects of Levosimendan and Sodium Nitroprusside Combination on Left Ventricular Functions After Surgical Ventricular Reconstruction in Coronary Artery Bypass Grafting Patients.
CONCLUSION: This study showed that LS and SNP combination impressive increase in left ventricular systolic and diastolic functions including LVEF. The use of this combination achieved more less inotrophics and IABP requirement. We therefore suggest preoperative and peroperative levosimendan and SNP combination.
PMID: 27583039 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Impaired Myocardial Bioenergetics in HFpEF and the Role of Antioxidants.
This article is a summative review of the recent relevant literature that addresses cardiac bioenergetics, deficiency in myocardial bioenergetics, and increased reactive oxygen species associated with HFpEF and the promising potential use of antioxidants in managing this condition.
PMID: 27583040 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Initial Experience with Renal Denervation for the Treatment of Resistant Hypertension - The Utility of Novel Anesthetics and Metaiodobenzylguanidine Scintigraphy (MIBG).
CONCLUSION: Patients with resistant hypertension who underwent RDN in our department had a significant reduction in BP 6 months after the intervention. (123)I-MIBG was not useful in predicting RDN response. Dexmedetomidine and remifentanil provided sufficient patient comfort during the procedure, allowing an adequate number of ablations per renal artery to be performed, and this could probably lead to improved RDN results.
PMID: 27583041 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Comparison of the Effects of Dialysis Methods (Haemodialysis vs Peritoneal Dialysis) on Diastolic Left Ventricular Function Dialysis Methods and Diastolic Function.
CONCLUSION: The method of dialysis seems to influence LV diastolic function. We observed a higher prevalence of diastolic LV dysfunction in the PD group. Echocardiographic follow up is essential as this could improve the management of cardiovascular complications in dialysis patients.
PMID: 27583042 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - September 3, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
Cardiac Dual-source Computed Tomography for the Detection of Left Main Compression Syndrome in Patients with Pulmonary Hyper-tension.
CONCLUSION: DSCT may represent the initial testing modality in PH patients with dilated PA trunk to exclude LMCS. A periodical rule-out of this rare entity, as assessed by DSCT, in patients with a severely dilated PA seems to be mandatory for PH patients contributing to survival improvement.
PMID: 27499817 [PubMed] (Source: Open Cardiovascular Medicine Journal)
Source: Open Cardiovascular Medicine Journal - August 9, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
