Micellar solubilisation enhances the antiinflammatory activities of curcumin and boswellic acids in rats with adjuvant-induced arthritis
Inflammation is one of the major causes of the development of various diseases like arthritis, cancer, cardiovascular disease, diabetes, obesity, osteoporosis, inflammatory bowel disease, asthma, and even central nervous system (CNS)-related diseases such as depression and Parkinson's disease [1]. Reports in the literature suggest that almost 90% of synthetic antiinflammatory drugs produce drug-related toxicities, iatrogenic reactions, and adverse effects compromising the treatment process [2,3]. (Source: Nutrition)
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Mohamed T. Khayyal, Rania M. El-Hazek, Walaa A. El-Sabbagh, Jan Frank, Dariush Behnam, Mona Abdel-Tawab Tags: Basic nutritional investigation Source Type: research
Protective effect of the riboflavin-overproducing strain Lactobacillus plantarum CRL2130 on intestinal mucositis in mice
Mucositis refers to mucosal inflammation and frequently occurs as a side effect of cancer treatments such as chemotherapy and radiation therapy. Fluorouracil (5-FU) is one of the most prescribed chemotherapeutic agents because of its ability to interrupt DNA synthesis and stimulate cell apoptosis [1]. However, one important limitation of 5-FU use is that this drug is not cell-specific because of cytotoxic exertion on both cancerous and other fast-reproducing cells [2]. In this sense, the intestinal epithelium is one of the tissues most sensitive to 5-FU because it is one of the most rapidly renewing tissues in adult mammal...
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Romina Levit, Graciela Savoy de Giori, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc Tags: Basic nutritional investigation Source Type: research
Micellar solubilisation enhances the anti-inflammatory activities of curcumin and boswellic acids in rats with adjuvant-induced arthritis
Using advanced micellation technology, stable solubilisates of curcumin and boswellia extracts with markedly enhanced bioavailability were prepared. The drugs were given daily for 3 weeks, starting from the day of Freund complete adjuvant innoculation. Solubilized curcumin showed a reduction in paw volume, tumor necrosis factor- α, interleukin-6 and C-reactive protein, myloperoxidase and lipid peroxidation markers as well as an increase in total antioxidant capacity, an effect which wass equivalent to diclofenac. (Source: Nutrition)
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Mohamed T. Khayyal, Rania M. El-Hazek, Walaa A. El-Sabbagh, Jan Frank, Dariush Behnam, Mona Abdel-Tawab Source Type: research
Protective effect of the riboflavin-overproducing strain lactobacillus plantarum CRL 2130 on intestinal mucositis in mice
Mucositis refers to mucosal inflammation and frequently occurs as a side effect of cancer treatments such as chemotherapy and radiotherapy. Fluorouracil (5-FU) is one of the most prescribed chemotherapeutic agents, due to its ability to interrupt DNA (deoxyribonucleic acid) synthesis and to stimulate cell apoptosis [1]. However, one important limitation of 5-FU use is that this drug is not cell specific since it exerts cytotoxity not only on cancerous cells, but also on other fast reproducing ones [2]. (Source: Nutrition)
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Romina Levit, Graciela Savoy de Giori, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc Source Type: research
Micellar solubilisation enhances the anti-inflammatory activities of curcumin and boswellic acids in rats with adjuvant-induced arthritis
Using advanced micellation technology, stable solubilisates of curcumin and boswellia extracts with markedly enhanced bioavailability were prepared. The drugs were given daily for 3 weeks, starting from the day of Freund complete adjuvant innoculation. Solubilized curcumin showed a reduction in paw volume, tumor necrosis factor- α, interleukin-6 and C-reactive protein, myloperoxidase and lipid peroxidation markers as well as an increase in total antioxidant capacity, an effect which wass equivalent to diclofenac. (Source: Nutrition)
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Mohamed T. Khayyal, Rania M. El-Hazek, Walaa A. El-Sabbagh, Jan Frank, Dariush Behnam, Mona Abdel-Tawab Source Type: research
Protective effect of the riboflavin-overproducing strain lactobacillus plantarum CRL 2130 on intestinal mucositis in mice
Mucositis refers to mucosal inflammation and frequently occurs as a side effect of cancer treatments such as chemotherapy and radiotherapy. Fluorouracil (5-FU) is one of the most prescribed chemotherapeutic agents, due to its ability to interrupt DNA (deoxyribonucleic acid) synthesis and to stimulate cell apoptosis [1]. However, one important limitation of 5-FU use is that this drug is not cell specific since it exerts cytotoxity not only on cancerous cells, but also on other fast reproducing ones [2]. (Source: Nutrition)
Source: Nutrition - April 23, 2018 Category: Nutrition Authors: Romina Levit, Graciela Savoy de Giori, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc Source Type: research
Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial
As a result of the rapid increases in the prevalence of type 2 diabetes mellitus and obesity, non-nutritive sweeteners (NNS) have become popular as alternatives to added sugars because they contain no or fewer calories while preserving palatability [1,2]. Unexpectedly, an accumulation of studies have suggested that NNS may increase the risk of excessive weight gain [3], metabolic syndrome [4,5], and type 2 diabetes mellitus [6,7]. There are several potential mechanisms that may induce NNS to cause glucose intolerance. (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Amornpan Lertrit, Sasinee Srimachai, Sunee Saetung, Suwannee Chanprasertyothin, La-or Chailurkit, Chatvara Areevut, Pornalat Katekao, Boonsong Ongphiphadhanakul, Chutintorn Sriphrapradang Tags: Applied nutritional investigation Source Type: research
Association of proinflammatory diet with low-grade inflammation: results from the Moli-sani study
It has been shown that dietary components are associated with a variety of chronic conditions ranging from cardiovascular diseases (CVDs) to cancer and mental disorders [1 –4]. Acute inflammatory response is the process of the body's natural reaction to injury or infection to heal wounds and promote tissue regeneration [5,6]. Chronic, low-grade (or subclinical) systemic inflammation is associated with numerous chronic conditions [7,8] and the ironic inability to mou nt a competent immune response to injury or infection [9]. (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Nitin Shivappa, Marialaura Bonaccio, James R. Hebert, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, George Pounis, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Moli-sani study Investigators Tags: Applied nutritional investigation Source Type: research
Effects of Sucralose on Insulin and GLP-1 Secretion in Healthy Subjects: A Randomized Double-Blind, Placebo Controlled Trial
• Four-week consumption of sucralose decreased insulin sensitivities in healthy volunteers.• Acute insulin response was also reduced after sucralose consumption.• Glucose-stimulated GLP-1 secretion was enhanced after chronic sucralose exposure.• Sucralose is not metabolically inactive, but a ffects insulin and GLP-1 responses (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Amornpan Lertrit, Sasinee Srimachai, Sunee Saetung, Suwannee Chanprasertyothin, La-or Chailurkit, Chatvara Areevut, Pornalat Katekao, Boonsong Ongphiphadhanakul, Chutintorn Sriphrapradang Source Type: research
Association of pro-inflammatory diet with low-grade inflammation: results from the moli-sani study
Dietary components have been shown to be associated with a variety of chronic conditions ranging from cardiovascular diseases to cancer and mental disorders [1-4]. Acute inflammatory response is the process of body's natural reaction to injury or infection in order to heal wounds and promote tissue regeneration [5,6]. Chronic, low-grade (or subclinical) systemic inflammation is associated with numerous chronic conditions [7,8] and the ironic inability to mount a competent immune response to injury or infection [9]. (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Nitin Shivappa, Marialaura Bonaccio, James R. Hebert, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, George Pounis, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Moli-sani study Investigators Source Type: research
Effects of Sucralose on Insulin and GLP-1 Secretion in Healthy Subjects: A Randomized Double-Blind, Placebo Controlled Trial
• Four-week consumption of sucralose decreased insulin sensitivities in healthy volunteers.• Acute insulin response was also reduced after sucralose consumption.• Glucose-stimulated GLP-1 secretion was enhanced after chronic sucralose exposure.• Sucralose is not metabolically inactive, but a ffects insulin and GLP-1 responses (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Amornpan Lertrit, Sasinee Srimachai, Sunee Saetung, Suwannee Chanprasertyothin, La-or Chailurkit, Chatvara Areevut, Pornalat Katekao, Boonsong Ongphiphadhanakul, Chutintorn Sriphrapradang Source Type: research
Association of pro-inflammatory diet with low-grade inflammation: results from the moli-sani study
Dietary components have been shown to be associated with a variety of chronic conditions ranging from cardiovascular diseases to cancer and mental disorders [1-4]. Acute inflammatory response is the process of body's natural reaction to injury or infection in order to heal wounds and promote tissue regeneration [5,6]. Chronic, low-grade (or subclinical) systemic inflammation is associated with numerous chronic conditions [7,8] and the ironic inability to mount a competent immune response to injury or infection [9]. (Source: Nutrition)
Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Nitin Shivappa, Marialaura Bonaccio, James R. Hebert, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, George Pounis, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Moli-sani study Investigators Source Type: research
Changes in food habits in cancer patients in Italy: a survey. AIOM - SINPE - FAVO
Over the past 50 y, the role of diet as a potentially modifiable risk factor for the development of diseases [1] has been increasing. The World Cancer Research Fund (WCRF) has a Continuous Update Project that analyses global research on how diet, nutrition, physical activity, and weight affect cancer risk and survival to update the cancer prevention recommendations, published in 2007 [2]. (Source: Nutrition)
Source: Nutrition - April 19, 2018 Category: Nutrition Authors: Cecilia Gavazzi, Sabina Sieri, Francesca Tracl ò, Alessandro Sproviero, Giulia Vandoni, Roberta Ricci, Silvia Stragliotto, Vittorina Zagonel, AIOM-SINPE-FAVO working group Tags: Brief report Source Type: research
Ultrasound measurement of intraabdominal fat thickness as a predictor of insulin resistance and low HDL cholesterol in Asians
There has been a growing interest in regional body fat distribution rather than total body fat per se as a metabolic risk factor. Numerous studies have suggested that obesity-related metabolic abnormalities are usually linked to intraabdominal fat accumulation [1 –5]. In 1983, Tokunaga et al. [6] used computed tomography (CT) to classify abdominal fat into two types (i.e., visceral and subcutaneous fat). Compared with subcutaneous fat, visceral fat is associated more often with abnormal glucose tolerance or diabetes, hyperlipidemia, hypertension, and insu lin resistance (IR) [7–9]. (Source: Nutrition)
Source: Nutrition - April 19, 2018 Category: Nutrition Authors: Xinyan Bi, Yi Ting Loo, Christiani Jeyakumar Henry Tags: Applied nutritional investigation Source Type: research
Low calcium intakes among Australian adolescents and young adults are associated with higher consumption of discretionary foods and beverages
Calcium is an essential nutrient required for peak bone mass growth during adolescence and into young adulthood. The aim of this study was to examine the calcium intake of Australian adolescents and young adults from both food sources and supplements; and the relationship between calcium intake and intake of food groups. (Source: Nutrition)
Source: Nutrition - April 19, 2018 Category: Nutrition Authors: Anika Saiyara Rouf, Zhixian Sui, Anna Rangan, Amanda Grech, Margaret Allman-Farinelli Tags: Applied nutritional investigation Source Type: research
