Neuropathology and Applied Neurobiology 
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Neuropathology and Applied Neurobiology, Ahead of Print. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 27, 2017 Category: Neurology Source Type: research
Myoblots: dystrophin quantification by in ‐cell western assay for a streamlined development of Duchenne muscular dystrophy (DMD) treatments
ConclusionsWe expect that this new tool to quantify muscle proteins in DMD and other muscle disorders will aid in their diagnosis and in the development of new therapies. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 27, 2017 Category: Neurology Authors: E. Ruiz ‐Del‐Yerro, I. Garcia‐Jimenez, K. Mamchaoui, V. Arechavala‐Gomeza Tags: Original Article Source Type: research
Low FoxG1 and high Olig ‐2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)‐mutant gliomas
ConclusionsWhile the combined FoxG1/Olig‐2 profile may discriminate H3F3A K27‐ and G34‐mutant tumours and define a prognostically favourable subset in IDH‐mutant gliomas, our data show that labelling indices of these transcription factors overlap with adult IDH‐mutant and wild‐type tumour classes. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 23, 2017 Category: Neurology Authors: S. Sch äfer, F. Behling, M. Skardelly, M. Koch, I. Ott, F. Paulsen, G. Tabatabai, J. Schittenhelm Tags: Original Article Source Type: research
Animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 12, 2017 Category: Neurology Authors: Albert J. Becker Tags: Invited Review Source Type: research
Concomitant IDH ‐wildtype glioblastoma and IDH1‐mutant anaplastic astrocytoma in a patient with constitutional mismatch repair deficiency syndrome
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 12, 2017 Category: Neurology Authors: Francesca Galuppini, Enrico Opocher, Uri Tabori, Isabella Mammi, Melissa Edwards, Britany Campbell, Jacalyn Kelly, Alessandra Viel, Michele Quaia, Francesca Rivieri, Domenico D'Avella, Antonella Arcella, Felice Giangaspero, Matteo Fassan, Marina Paola Gar Tags: Scientific Correspondence Source Type: research
Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease
Our understanding of the underlying biology of Alzheimer's disease (AD) has been steadily progressing; however, this is yet to translate into a successful treatment in humans. The use of transgenic mouse models has helped to develop our understanding of AD, not only in terms of disease pathology, but also with the associated cognitive impairments typical of AD. Plaques and neurofibrillary tangles are often among the last pathological changes in AD mouse models, after neuronal loss and gliosis. There is a general consensus that successful treatments need to be applied before the onset of these pathologies and associated cog...
Source: Neuropathology and Applied Neurobiology - November 9, 2017 Category: Neurology Authors: K. E. Ameen ‐Ali, S. B. Wharton, J. E. Simpson, P. R. Heath, P. Sharp, J. Berwick Tags: Review Source Type: research
In This Issue
(Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 9, 2017 Category: Neurology Tags: In This Issue Source Type: research
Issue Information
(Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 9, 2017 Category: Neurology Tags: Issue Information Source Type: research
Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post mortem study
Neuropathology and Applied Neurobiology,Volume 44, Issue 3, Page 298-313, April 2018. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 17, 2017 Category: Neurology Source Type: research
Myoblots: dystrophin quantification by in ‐cell western assay for a streamlined development of DMD treatments
ConclusionsWe expect that this new tool to quantify muscle proteins in DMD and other muscle disorders will aid in their diagnosis and in the development of new therapies.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Est íbaliz Ruiz‐Del‐Yerro, Iker Garcia‐Jimenez, Kamel Mamchaoui, Virginia Arechavala‐Gomeza Tags: Original Article Source Type: research
Low FoxG1 and high Olig ‐2 labelling indices define a prognostically favorable subset in IDH‐mutant gliomas
ConclusionsWhile the combined FoxG1/Olig‐2 profile may discriminate H3F3A K27‐ and G34‐mutant tumors and define a prognostically favourable subset in IDH‐mutant gliomas, our data show that labelling indices of these transcription factors overlap with adult IDH‐mutant and wildtype tumor classes.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Sarah Sch äfer, Felix Behling, Marco Skardelly, Marilin Koch, Ines Ott, Frank Paulsen, Ghazaleh Tabatabai, Jens Schittenhelm Tags: Original Article Source Type: research
Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post ‐mortem study
ConclusionsOverall, we found that the neuroinflammatory pathological markers in late stage AD human tissue to have a similar pattern in both EOAD and LOAD, though the severity of the pathological markers in the younger group was higher. Understanding the age effect in AD will be important when testing modifying agents that act on the neuroinflammation.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Ricardo Taipa, Vitor Ferreira, Paulo Brochado, Andrew Robinson, In ês Reis, Fernanda Marques, David M Mann, Manuel Melo Pires, Nuno Sousa Tags: Original Article Source Type: research
Neuroinflammatory pathways as treatment targets and biomarker candidates in epilepsy: emerging evidence from preclinical and clinical studies
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - October 1, 2017 Category: Neurology Authors: Erwin A. van Vliet, Eleonora Aronica, Annamaria Vezzani, Teresa Ravizza Tags: Annual Review Issue ‐Review Source Type: research
CNS embryonal tumours: WHO 2016 and beyond
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - September 26, 2017 Category: Neurology Authors: Jessica C Pickles, Cynthia Hawkins, Torsten Pietsch, Thomas S Jacques Tags: Short Review Source Type: research
