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Strategies in genotoxicology: Acceptance of innovative scientific methods in a regulatory context and from an industrial perspective
Publication date: Available online 18 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Guy Steiblen, Jan van Benthem, Georges Johnson (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 20, 2020 Category: Genetics & Stem Cells Source Type: research

Key Read Across Framework Components and Biology Based Improvements
Publication date: Available online 16 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Nicholas Ball, Judith Madden, Alicia Paini, Miriam Mathea, Andrew David Palmer, Saskia Sperber, Thomas Hartung, Bennard van Ravenzwaay (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 17, 2020 Category: Genetics & Stem Cells Source Type: research

Increased micronucleus frequencies in reticulocytes of children exposed to industrial pollution: oxidative stress and the OGG1 S326C polymorphism
Publication date: Available online 14 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Regina D. Montero-Montoya, Rocío López-Vargas, Alejandra Méndez-Serrano, Isaías Galicia-Alonso, Guadalupe García-Vargas, Luis Serrano-García, Rosa Beltrán-Portugal, Samuel Rosado-Zaidi, Arnulfo Albores-Medina, Luis Oropeza-Hernández, Leticia Hernández-Cadena, Francisco Mercado-Calderón, Esmeralda Alvarado-Toledo, Selene Herrera-Morales, Omar Arellano-Aguilar (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 15, 2020 Category: Genetics & Stem Cells Source Type: research

Genotoxic and cytotoxic properties of two medical plants (Teucrium arduini L. And Teucrium flavum L.) in relation to their polyphenolic contents
Publication date: Available online 12 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Darko Grujicic, Aleksandra Markovic, Jovana Tubic Vukajlovic, Milan Stankovic, Marina Radovic Jakovljevic, Andrija Ciric, Katarina Djordjevic, Nevena Planojevic, Milena Milutinovic, Olivera Milosevic-Djordjevic (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 12, 2020 Category: Genetics & Stem Cells Source Type: research

Benchmark dose analyses of γH2AX and pH3 endpoints for quantitative comparison of in vitro genotoxicity potential of lipophilic phycotoxins
Publication date: Available online 10 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Ludovic Le Hegarat, Alain-Claude Roudot, Valérie Fessard (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 11, 2020 Category: Genetics & Stem Cells Source Type: research

Loci associated with genomic damage levels in chronic kidney disease patients and controls
Publication date: Available online 10 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Zuray Corredor, Miguel Inácio da Silva Filho, Lara Rodríguez-Ribera, Calogerina Catalano, Kari Hemminki, Elisabeth Coll, Irene Silva, Juan Manuel Diaz, José Aurelio Ballarin, Alba Henández, Asta Försti, Ricard Marcos, Susana Pastor (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 11, 2020 Category: Genetics & Stem Cells Source Type: research

Preface to the Special Issue dedicated to the 47th annual conference of the European Environmental Mutagen and Genomics Society (EEMGS)
Publication date: Available online 7 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Helga Stopper, Lisbeth E. Knudsen, Ludovic Le Hegarat (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 8, 2020 Category: Genetics & Stem Cells Source Type: research

Evaluation of the genotoxic potential of apoptosis inducers with the γH2AX assay in human cells
Publication date: Available online 5 March 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Laure Khoury, Daniel Zalko, Marc Audebert (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 7, 2020 Category: Genetics & Stem Cells Source Type: research

The Iberian legacy into a young genetic xeroderma pigmentosum cluster in central Brazil
Publication date: Available online 29 February 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): L.P. Castro, M. Sahbatou, F.S.G. Kehdy, A. A Farias, A.A. Yurchenko, T.A. de Souza, R.C.A. Rosa, C.T. Mendes-Junior, V. Borda, V. Munford, É.A. Zanardo, S.N. Chehimi, L.D. Kulikowski, M.M. Aquino, T.P. Leal, E. Tarazona-Santos, S.C. Chaibub, B. Gener, N. Calmels, V. Laugel (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - March 1, 2020 Category: Genetics & Stem Cells Source Type: research

Cardiac catheterization procedures in children with congenital heart disease: increased chromosomal aberrations in peripheral lymphocytes
Publication date: Available online 25 February 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Yu Gao, Ping Wang, Yinping Su, Zhaonan Wang, Lin Han, Jie Li, Yinghua Fu, Fengling Zhao, Quanfu Sun, Yumin Lyu (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 27, 2020 Category: Genetics & Stem Cells Source Type: research

Occupational exposure of dental technicians to methyl methacrylate: genotoxicity assessment
Publication date: Available online 25 February 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Buğra Soykut, Onur Erdem, Can Özgür Yalçin, Aylin Üstündağ, Yalçın Duydu, Cemal Akay, Bülent Pişkin (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 27, 2020 Category: Genetics & Stem Cells Source Type: research

Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase
Publication date: Available online 22 February 2020Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Lindsay Reed, Ian W.H. Jarvis, David H. Phillips, Volker M. ArltAbstractDiet is a major source of human exposure to polycyclic aromatic hydrocarbons (PAHs), of which benzo[a]pyrene (BaP) is the most commonly studied and measured. BaP has been considered to exert its genotoxic effects after metabolic activation by cytochrome P450 (CYP) enzymes whose activity can be modulated by cytochrome P450 oxidoreductase (POR), the electron donor to CYP enzymes. Previous studies showed that BaP-DNA addu...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 23, 2020 Category: Genetics & Stem Cells Source Type: research

Differential toxic effects of food contaminant mixtures in HepaRG cells after single or repeated treatments
In conclusion, our study demonstrated that longer-term treatments for in vitro toxicological evaluation, instead of the classical 24 h treatment, may be more relevant regarding human toxicology assessment. (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 21, 2020 Category: Genetics & Stem Cells Source Type: research

DNA damage, repair and the improvement of cancer therapy – a tribute to the life and research of Barbara Tudek
This article presents her outstanding character and most important lines of research. The focus of her studies covered alkylative and oxidative damage to DNA bases, in particular mutagenic and carcinogenic properties of purines with an open imidazole ring and 8-oxo-7,8-dihydroguanine (8-oxoGua). They also included analysis of mutagenic properties and pathways for the repair of DNA adducts of lipid peroxidation (LPO) products arising in large quantities during inflammation. Professor Tudek did all of this in the hope of deciphering the mechanisms of DNA damage removal, in particular by the base excision repair (BER) pathway...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 21, 2020 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: January 2020Source: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 849Author(s): (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - February 20, 2020 Category: Genetics & Stem Cells Source Type: research