Extract of the Microalga Nitzschia laevis Prevents High ‐Fat‐Diet Induced Obesity in Mice by Modulating the Composition of Gut Microbiota
Conclusions: NLE supplementation demonstrated a protective effect against HFD ‐induced obesity in mice, which was associated with reshaping the profile of gut microbiota. To the best of our knowledge, this has been the first report on the potential of microalgal extract to prevent obesity by modulating gut microbiota.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 26, 2018 Category: Nutrition Authors: Bingbing Guo,
Bin Liu,
Hehong Wei,
Ka ‐Wing Cheng,
Feng Chen Tags: Research Article Source Type: research
Transcriptional profiling of dendritic cells in a mouse model of food ‐antigen induced anaphylaxis reveals the upregulation of multiple immune‐related pathways
Conclusions: Our findings provide a comprehensive overview of the transcriptional changes occurring in DCs during anaphylaxis and help elucidate the mechanisms involved. They add further weight to the putative role of these cells in anaphylaxis and highlights genes that may represent potential therapeutic targets.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 20, 2018 Category: Nutrition Authors: Maria Jose Rodriguez,
Francisca Palomares,
Gador Bogas,
Maria Jose Torres,
Araceli Diaz ‐Perales,
Javier Rojo,
Maria del Carmen Plaza‐Seron,
Alba Rodriguez‐Nogales,
Christine Orengo,
Cristobalina Mayorga,
James Richard Perkins Tags: Research Article Source Type: research
Food ‐Derived Xeno‐microRNAs: Influence of Diet and Detectability in Gastrointestinal Tract—Proof‐of‐Principle Study
ConclusionsFood provides a great source of miRNAs and diet may be associated with changes in xenomiRs. Plant ‐derived miR‐168 is ubiquitously present in feces, normal mucosa, and cancer. Further studies are needed to evaluate the functional interaction between diet‐derived miRNAs and GI tract. (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 20, 2018 Category: Nutrition Authors: Jastin Link,
Cosima Thon,
Denny Schanze,
Ruta Steponaitiene,
Juozas Kupcinskas,
Martin Zenker,
Ali Canbay,
Peter Malfertheiner,
Alexander Link Tags: Research Article Source Type: research
Products of Early and Advanced Glycation in the Soy Milk Proteome
ConclusionThe qualitative and quantitative data obtained here indicted that early glycation increases with harsher processing conditions (SIFs) and the addition of hexose ‐containing sweeteners (SSMs), whereas the latter sweeteners, but not the harsher processing triggered more AGE‐modifications.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 15, 2018 Category: Nutrition Authors: Sanja Milkovska ‐Stamenova,
Laura Krieg,
Ralf Hoffmann Tags: Research Article Source Type: research
Body Mass Index as a determinant of systemic exposures to gallotannin metabolites during six ‐week consumption of mango (Mangifera Indica L.) and modulation of intestinal microbiota in lean and obese individuals
ConclusionContinuous mango intake significantly increased systemic exposure to gallotannin ‐ metabolites and induced increased trend for fecal short‐chain fatty acids in lean but not obese individuals. This pharmacokinetic discrepancy may result in BMI‐associated reduced gallotannin‐derived health benefits.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 14, 2018 Category: Nutrition Authors: Ryan C. Barnes,
Hyemee Kim,
Chuo Fang,
William Bennett,
Matthew Nemec,
Maritza A. Sirven,
Jan S. Suchodolski,
Nicolaas Deutz,
Robert A. Britton,
Susanne U. Mertens ‐Talcott,
Stephen T. Talcott Tags: Research Article Source Type: research
Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages
ConclusionsThese novel findings demonstrate remarkable plasticity of macrophages to respond to their environment with specific modulation of ABCA1 depending on whether classical pro ‐inflammatory or metabolic cues predominate.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 9, 2018 Category: Nutrition Authors: Marcella E. O'Reilly,
Sarina Kajani,
Jessica C. Ralston,
Yvonne M. Lenighan,
Helen M. Roche,
Fiona C. McGillicuddy Tags: Research Article Source Type: research
High ‐Saturated Fat High‐Sugar Diet Accelerates Left‐Ventricular Dysfunction Faster than High‐Saturated Fat Diet Alone via Increasing Oxidative Stress and Apoptosis in Obese‐Insulin Resistant Rats
Conclusion: Both HFD and HFHS caused cardiometabolic dysfunction. HFHS caused more severe metabolic disturbance, oxidative stress, and apoptosis than HFD, which led to an accelerated LV dysfunction in HFHS rats.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 9, 2018 Category: Nutrition Authors: Nattayaporn Apaijai,
Apiwan Arinno,
Siripong Palee,
Wasana Pratchayasakul,
Sasiwan Kerdphoo,
Thidarat Jaiwongkam,
Titikorn Chunchai,
Siriporn C Chattipakorn,
Nipon Chattipakorn Tags: Research Article Source Type: research
Higher Chain Length Distribution in Debranched Type ‐3 Resistant Starches (RS3) Increases TLR Signaling and Supports Dendritic Cell Cytokine Production
Conclusions: We show here that chain length and particularly dextrose equivalent are critical features for immune activation. This knowledge might lead to tailoring and design of immune active RS formulations.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 9, 2018 Category: Nutrition Authors: Alexia F.P. L épine,
Roderick H. J. Hilster,
Hans Leemhuis,
Lizette Oudhuis,
Piet L. Buwalda,
Paul Vos Tags: Research Article Source Type: research
Dietary Daidzein Supplementation During Pregnancy Facilitates Fetal Growth in Rats
ConclusionThese results not only indicate a beneficial effect of daidzein supplementation on reproductive performance but also offer potential mechanisms behind daidzein ‐facilitated fetal growth in rats. (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 9, 2018 Category: Nutrition Authors: Qiqi Zhang,
Hongmei Xie,
Daiwen Chen,
Bing Yu,
Zhiqing Huang,
Ping Zheng,
Xiangbing Mao,
Jie Yu,
Yuheng Luo,
Junqiu Luo,
Jun He Tags: Research Article Source Type: research
Human Milk Oligosaccharides Increase Mucin Expression in Experimental Necrotizing Enterocolitis
ConclusionsTaken together, our results provide insights to the possible mechanisms by which HMOs protect the neonatal intestine through upregulation of mucins.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 8, 2018 Category: Nutrition Authors: Richard You Wu,
Bo Li,
Yuhki Koike,
Pekka M äättänen,
Hiromu Miyake,
Marissa Cadete,
Kathene C. Johnson‐Henry,
Steven R. Botts,
Carol Lee,
Thomas R. Abrahamsson,
Eva Landberg,
Agostino Pierro,
Philip M. Sherman Tags: Research Article Source Type: research
Evaluation of 2 ‐thiothiazolidine‐4‐carboxylic Acid, a Common Metabolite of Isothiocyanates as a Potential Biomarker of Cruciferous Vegetable Intake
ConclusionCollectively, TTCA appears to be common isothiocyanate ‐derived metabolite that has the capacity to be utilized as a biomarker of cruciferous vegetables which would be beneficial for objective and quantitative tracking of intake in studies.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 8, 2018 Category: Nutrition Authors: Dushani L. Palliyaguru,
Sonia R. Salvatore,
Francisco J. Schopfer,
Xuemei Cheng,
Jingyang Zhou,
Thomas W. Kensler,
Stacy G. Wendell Tags: Research Article Source Type: research
Mild methylenetetrahydrofolate reductase deficiency alters inflammatory and lipid pathways in liver
ConclusionIndividuals with the MTHFR variant may be at increased risk for liver disease and related complications, particularly when consuming high ‐fat diets.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 8, 2018 Category: Nutrition Authors: Daniel Leclerc,
Karen E. Christensen,
Olivia Cauvi,
Ethan Yang,
Fr édéric Fournelle,
Renata H. Bahous,
Olga V. Malysheva,
Liyuan Deng,
Qing Wu,
Zili Zhou,
Gao Zu‐hua,
Pierre Chaurand,
Marie A. Caudill,
Rima Rozen Tags: Research Article Source Type: research
The Anti ‐Arthritis Effect of Olive‐Derived Maslinic Acid in mice is Due to its Promotion of Tissue Formation and its Anti‐Inflammatory Effects
ConclusionsThe preventive effect of MA on arthritis is attributable to the promotion of tissue formation as well as suppression of inflammation in the synovium via inactivation of Toll ‐like receptor signaling and downregulation of leukotrienes through the glucocorticoid receptor.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 8, 2018 Category: Nutrition Authors: Kyoko Shimazu,
Satoshi Fukumitsu,
Tomoko Ishijima,
Tsudoi Toyoda,
Yuji Nakai,
Keiko Abe,
Kazuhiko Aida,
Shinji Okada,
Akihiro Hino Tags: Research Article Source Type: research
p107 Deficiency Increases Energy Expenditure by Inducing Brown ‐fat Thermogenesis and Browning of White Adipose Tissue
Molecular Nutrition&Food Research,Volume 0, Issue ja, -Not available-. (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 1, 2018 Category: Nutrition Authors: Juan Cunarro,
Xabier Buque,
Sabela Casado,
Javier Lugilde,
Anxo Vidal,
Alfonso Mora,
Guadalupe Sabio,
Rub én Nogueiras,
Patricia Aspichueta,
Carlos Diéguez,
Sulay Tovar Source Type: research
Pigmented Rice ‐derived Phenolic Compounds Reduce Biomarkers of Oxidative Stress and Inflammation in Human Umbilical Vein Endothelial Cells
Molecular Nutrition&Food Research,Volume 0, Issue ja, -Not available-. (Source: Molecular Nutrition)
Source: Molecular Nutrition - November 1, 2018 Category: Nutrition Authors: Esther T Callcott,
Christopher L Blanchard,
Prakash Oli,
Abishek B Santhakumar Source Type: research
