Identification and characterization of acetyltransferase ‐type toxin‐antitoxin locus in Klebsiella pneumoniae
Molecular Microbiology, EarlyView. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 8, 2018 Category: Microbiology Source Type: research
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Molecular Microbiology, Ahead of Print. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 8, 2018 Category: Microbiology Source Type: research
Identification and characterization of acetyltransferase ‐type toxin‐antitoxin locus in Klebsiella pneumoniae
Summary
A type II toxin‐antitoxin (TA) system, in which the toxin contains a Gcn5‐related N‐acetyltransferase (GNAT) domain, has been characterized recently. GNAT toxin acetylates aminoacyl‐tRNA and blocks protein translation. It is abolished by the cognate antitoxin that contains the ribbon‐helix‐helix (RHH) domain. Here, we present an experimental demonstration of the interaction of the GNAT‐RHH complex with TA promoter DNA. First, the GNAT‐RHH TA locus kacAT was found in Klebsiella pneumoniae HS11286, a strain resistant to multiple antibiotics. Overexpression of KacT halted cell growth and resulted in pe...
Source: Molecular Microbiology - March 8, 2018 Category: Microbiology Authors: Hongliang Qian, Qingqing Yao, Cui Tai, Zixin Deng, Jianhua Gan, Hong ‐Yu Ou Tags: Research Article Source Type: research
Methionine is required for cAMP ‐PKA‐mediated morphogenesis and virulence of Candida albicans
Molecular Microbiology, EarlyView. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
DNA gyrase activity regulates DnaA ‐dependent replication initiation in Bacillus subtilis
Molecular Microbiology, EarlyView. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli
Molecular Microbiology, EarlyView. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
Structural insights into the binding and catalytic mechanisms of the Listeria monocytogenes bacteriophage glycosyl hydrolase PlyP40
Molecular Microbiology, EarlyView. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
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Molecular Microbiology, Ahead of Print. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
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Molecular Microbiology,Volume 107, Issue 6, March 2018. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
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Molecular Microbiology,Volume 107, Issue 6, Page i-i, March 2018. (Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Source Type: research
Issue Information
(Source: Molecular Microbiology)
Source: Molecular Microbiology - March 6, 2018 Category: Microbiology Tags: Issue Information Source Type: research
