Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass
Publication date: Available online 4 June 2021Source: Molecular MetabolismAuthor(s): Berta Serra-Navarro, Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, Marta Pradas-Juni, Eduardo Fernández-Rebollo, Yaiza Esteban, Joan Mir-Coll, Julia Mathieu, Stephane Dalle, Max Hahn, Ulf Ahlgren, Lee S. Weinstein, Josep Vidal, Ramon Gomis, Rosa Gasa (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 5, 2021 Category: Endocrinology Source Type: research

Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression
Publication date: Available online 5 June 2021Source: Molecular MetabolismAuthor(s): Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 5, 2021 Category: Endocrinology Source Type: research

LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway
Publication date: Available online 5 June 2021Source: Molecular MetabolismAuthor(s): Sonia Spinelli, Giulia Begani, Lucrezia Guida, Mirko Magnone, Denise Galante, Cristina D’Arrigo, Claudia Scotti, Luisa Iamele, Hugo De Jonge, Elena Zocchi, Laura Sturla (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 5, 2021 Category: Endocrinology Source Type: research

Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions
Publication date: Available online 21 May 2021Source: Molecular MetabolismAuthor(s): Deepali Gupta, Anna M. Patterson, Sherri Osborne-Lawrence, Angie L. Bookout, Salil Varshney, Kripa Shankar, Omprakash Singh, Nathan P. Metzger, Corine P. Richard, Steven C. Wyler, Joel K. Elmquist, Jeffrey M. Zigman (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 4, 2021 Category: Endocrinology Source Type: research

Hemostatic alterations linked to body fat distribution, fatty liver and insulin resistance
Publication date: Available online 31 May 2021Source: Molecular MetabolismAuthor(s): Sebastian Hörber, Rainer Lehmann, Norbert Stefan, Jürgen Machann, Andreas L. Birkenfeld, Robert Wagner, Martin Heni, Hans-Ulrich Häring, Andreas Fritsche, Andreas Peter (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 1, 2021 Category: Endocrinology Source Type: research

Understanding insulin and its receptor from their three-dimensional structures
Publication date: Available online 13 May 2021Source: Molecular MetabolismAuthor(s): Michael C. Lawrence (Source: Molecular Metabolism)
Source: Molecular Metabolism - June 1, 2021 Category: Endocrinology Source Type: research

Insulin action, type 2 diabetes, and branched-chain amino acids: a two-way street
Publication date: Available online 24 May 2021Source: Molecular MetabolismAuthor(s): Phillip J. White, Robert W. McGarrah, Mark A. Herman, James R. Bain, Svati H. Shah, Christopher B. Newgard (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 26, 2021 Category: Endocrinology Source Type: research

Antagonistic epistasis of Hnf4α and FoxO1 metabolic networks through enhancer interactions in β-cell function
Publication date: Available online 25 May 2021Source: Molecular MetabolismAuthor(s): Taiyi Kuo, Wen Du, Yasutaka Miyachi, Prasanna K. Dadi, David A. Jacobson, Daniel Segrè, Domenico Accili (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 26, 2021 Category: Endocrinology Source Type: research

Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
Publication date: Available online 23 May 2021Source: Molecular MetabolismAuthor(s): Nicolas O. Jørgensen, Rasmus Kjøbsted, Magnus R. Larsen, Jesper B. Birk, Nicoline R. Andersen, Bina Albuquerque, Peter Schjerling, Russell Miller, David Carling, Christian K. Pehmøller, Jørgen F.P. Wojtaszewski (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 24, 2021 Category: Endocrinology Source Type: research

Myosin 1c: A novel regulator of glucose uptake in brown adipocytes
Publication date: Available online 7 May 2021Source: Molecular MetabolismAuthor(s): Alice Åslund, Muhammad Hamza Bokhari, Erika Wetterdal, René Martin, Hans-Joachim Knölker, Tore Bengtsson (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 22, 2021 Category: Endocrinology Source Type: research

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes
Publication date: Available online 12 May 2021Source: Molecular MetabolismAuthor(s): Daniel S. de Jesus, Tracy C.S. Mak, Yi-Fang Wang, Yorrick von Ohlen, Ying Bai, Eva Kane, Pauline Chabosseau, Catherine M. Chahrour, Walter Distaso, Victoria Salem, Alejandra Tomas, Markus Stoffel, Guy A. Rutter, Mathieu Latreille (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 22, 2021 Category: Endocrinology Source Type: research

Disrupting the ghrelin-growth hormone axis limits ghrelin’s orexigenic but not glucoregulatory actions
Publication date: Available online 21 May 2021Source: Molecular MetabolismAuthor(s): Deepali Gupta, Anna M. Patterson, Sherri Osborne-Lawrence, Angie L. Bookout, Salil Varshney, Kripa Shankar, Omprakash Singh, Nathan P. Metzger, Corine P. Richard, Steven C. Wyler, Joel K. Elmquist, Jeffrey M. Zigman (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 21, 2021 Category: Endocrinology Source Type: research

Deconstructing the Origins of Sexual Dimorphism in Sensory Modulation of Pancreatic β Cells
Publication date: Available online 21 May 2021Source: Molecular MetabolismAuthor(s): Sara McEwan, Hyokjoon Kwon, Azeddine Tahiri, Nivetha Shanmugarajah, Weikang Cai, Jin Ke, Tianwen Huang, Ariana Belton, Bhagat Singh, Le Wang, Zhiping Pang, Ercument Dirice, Esteban A. Engel, Abdelfattah El Ouaamari (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 21, 2021 Category: Endocrinology Source Type: research

Insulin-like growth factors: Ligands, binding proteins, and receptors
Publication date: Available online 4 May 2021Source: Molecular MetabolismAuthor(s): Derek LeRoith, Jeff M.P. Holly, Briony Forbes (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 20, 2021 Category: Endocrinology Source Type: research

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
Publication date: Available online 4 May 2021Source: Molecular MetabolismAuthor(s): Georgina K.C. Dowsett, Brian Y.H. Lam, John A. Tadross, Irene Cimino, Debra Rimmington, Anthony P. Coll, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, Giles S.H. Yeo (Source: Molecular Metabolism)
Source: Molecular Metabolism - May 20, 2021 Category: Endocrinology Source Type: research