Radium-223 in mCPRC patients: a large real-life Italian multicenter study.
CONCLUSIONS: This study offers a cross-section of the clinical performance of Radium-223 treatment in a real-world context, confirming on a large scale the effectiveness of Radium-223 in improving the OS and quality of life, along with the preservation of an excellent safety profile. PMID: 32748619 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 13, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Retzius-sparing robot-assisted radical prostatectomy versus open retropubic radical prostatectomy: a prospective comparative study with 19-month follow-up.
CONCLUSIONS: RS-RARP had better perioperative outcomes and faster recovery of urinary continence compared with ORP. Short-term oncological outcomes were comparable between both surgical approaches. PMID: 32748620 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 13, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Robot-assisted laparoscopic pyeloplasty in children: a systematic review.
CONCLUSIONS: RALP offers excellent outcomes in the pediatric population. However, there is still a strong need for higher quality evidence in the form of prospective observational studies and clinical trials. The rising of new robotic systems, such as single-port platform, might further enhance the applications of RALP in children. PMID: 32748621 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 13, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Functional and oncological outcomes of 3D clampless sutureless laparoscopic partial nephrectomy for renal tumors with low nephrometry score.
CONCLUSIONS: Different techniques has been proposed to reduce WIT. In our experience we found many benefits in an off-clamp procedure: it gives an ischemiarelated advantage, reduces the overall operating time, eliminates the risks associated with the isolation of hilar vassels. In conclusion CSLPN is a safe and effective procedure for selected renal masses; it doesn't increase complication rate and offers excellent functional and oncological outcomes. PMID: 32748622 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 13, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Triggers for delayed intervention in patients with small renal masses undergoing active surveillance: a systematic review.
CONCLUSIONS: The available evidence shows that both tumor-related and patient-related factors are ultimate triggers for DI in patients with SRMs undergoing AS. However, the level of evidence is still low and further research is needed to individualize AS strategies according to both tumor biology and patient-related characteristics and values. PMID: 32734748 [PubMed - in process] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 1, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Complications and quality of life of ileal conduit, orthotopic neobladder and ureterocutaneostomy: systematic review of reports using the Clavien-Dindo Classification.
CONCLUSIONS: The use of a standardized system such as CCS improves analyses of literature. However, rigorous patient selection for UD type makes unable a randomized comparison between UDs in terms of complications and QoL impact. PMID: 32734749 [PubMed - in process] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - August 1, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Four dilation techniques in percutaneous nephrolithotomy: a single-institute comparative analysis.
CONCLUSIONS: Different dilation methods are equally effective and safe to use in a PCNL procedurefor kidney stone treatment, allowing similar stone free rates and risk of complications. The OS dilation techniques seem to allow a shorter X-ray exposure time, which might be beneficial for both patients and operators. The use of a 16F dilator can reduce the postoperative morbidity. Risk of sepsis should be always kept in mind. PMID: 32638574 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - July 10, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Artifacts and abnormal findings may limit the use of asymptomatic volunteers as controls for studies of multi-channel urodynamics.
CONCLUSIONS: This study demonstrated that healthy, asymptomatic volunteers have high rates of abnormal urodynamic findings, suggesting that asymptomatic participants are not the ideal controls in research studies that involve urodynamic testing. PMID: 32638575 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - July 10, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Focal irreversible electroporation for localized prostate cancer management: prospective assessment of efficacy and safety.
Authors: Enikeev D, Taratkin M, Morozov A, Shpikina A, Singla N, Rivas JG, Barret E, Glybochko P PMID: 32638576 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - July 10, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

What is the role of residents during a pandemic?
Authors: Esperto F, Papalia R, Pang KH, Cataldo R, Scarpa RM PMID: 32580536 [PubMed - in process] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - June 27, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

On-clamp versus purely off-clamp robot-assisted partial nephrectomy in solitary kidneys: comparison of perioperative outcomes and chronic kidney disease progression at two high- volume centers.
CONCLUSIONS: eGFRd and WIT during RPN are independent predictors of pCKD in SK. In this setting a critical reduction of WIT should be achieved according to the oncologic outcome. In patients with SK, WIT represents the only surgical modifiable factor of RPN for avoiding a quicker onset of pCKD. PMID: 32573170 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - June 24, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Is urodynamic evaluation able to change and improve the management of women with idiopathic overactive bladder?
CONCLUSIONS: we showed that OAB management tailored according to the UDS diagnosis results in higher subjective satisfaction if compared with a pharmacological treatment symptoms-based. Our study confirmed a lack of correlation between OAB symptoms and the urodynamically proven diagnosis of detrusor overactivity (DO). It also suggested that UDS can determine the underlying pathophysiology of every woman with OAB syndrome, whether complicated or uncomplicated, allowing treatment to be appropriately tailored with better results. PMID: 32573171 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - June 24, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Bipolar plasmakinetic transurethral enucleation and resection versus bipolar plasmakinetic transurethral resection for surgically treating large ( ≥ 60 g) prostates: a propensity score-matched analysis with a 3-year follow-up.
CONCLUSIONS: For patients with large (≥ 60 g) prostates, BP-TUERP and BP-TURP are safe options, but the former is a more effective choice in long-term follow-up outcomes. BP-TUERP is related to reduced CT and hemoglobin decrease with more removal of prostatic tissue at the expense of longer OT than BP-TURP. PMID: 32573172 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - June 24, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

The efficacy and safety of the tranexamic acid in reducing blood loss and transfusion requirements during percutaneous nephrolithotomy: a systematic review and meta-analysis of randomized controlled trials.
CONCLUSIONS: Our work assessing the use of TA in the clinical management of patients undergoing PCNL indicated promising results. Further well-designed trials are warranted to determine the optimal dose and indications of this drug in practice. PMID: 32573173 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - June 24, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Urologic surgery in a safe hospital during the COVID-19 pandemic scenario.
Authors: Papalia R, Cataldo R, Alloni R, Pang KH, Alcini A, Flammia G, Salerno A, Notarangelo MG, Angeletti S, Venditti A, Sommella L, Scarpa RM, Esperto F Abstract The COVID-19 pandemic induced a global emergency that overwhelmed most hospitals around the world. Access to Hospitals has been restricted to selective oncological and urgent patients to minimize surgeries requiring Intensive Care Unit care. All other kind of non- urgent and benign surgeries have been rescheduled. The burden of oncological and urgent cases on the healthcare system has increased. We have been asked to become the referral center ...
Source: Minerva Urologica e Nefrologica - June 24, 2020 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research