Ventricular fibrillation induced by 2-aminoethoxydiphenyl borate under conditions of hypoxia/reoxygenation.
CONCLUSIONS: The obtained results indicate that the effect of arrhythmogenic chemicals, for example, proarrhythmic drugs that affect the myocardial [Ca2+]in, depended on the oxygen supply to the heart. The components of the store operated calcium entry and gap junctions can become promising therapeutic targets for controlling the physiological disorders of the heart and blood vessels caused or accompanied by reoxygenation.
PMID: 33059404 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Further advancement in the percutaneous revascularization of coronary chronic total occlusions: the redefined "Minimalistic Hybrid Approach" algorithm.
Authors: Vescovo GM, Zivelonghi C, Scott B, Agostoni P
Abstract
A careful angiographic assessment of a chronic total occlusion (CTO) is essential for optimal procedural planning. In the classic Hybrid Approach, the insertion of two guiding catheters at the beginning of the intervention is recommended. This is fundamental to perform simultaneous double injection, to achieve complete visualization of the coronary circulation and to choose the best starting strategy between antegrade wire escalation (AWE), antegrade dissection and re-entry (ADR) and the retrograde techniques (retrograde wire escalation [RWE] ...
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Ventricular arrhythmic risk prediction: simpler is easier.
Authors: Radu S, Floria M
PMID: 33059406 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Sodium-glucose co-transporter-2 inhibitors in heart failure patients: an appraisal of recent cardiovascular outcome trials.
Authors: Kocyigit D, Kocyigit AS, Hussain M
Abstract
Although initially introduced as a novel oral glucose-lowering agent class, cumulative evidence from randomized controlled trials (RCTs) have led sodium-glucose co-transporter-2 inhibitors (SGLT2i) to become a component of primary and secondary prevention of atherosclerotic cardiovascular disease management in patients with type 2 diabetes mellitus (T2DM). Dapagliflozin, one of the agents of this class, was investigated in 2019 in patients with heart failure (HF) independent of being diagnosed with T2DM at baseline. Since then, many other studies in this...
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Potential use of frontal QRS-T angle for sudden death risk stratification in athletes.
Authors: Scacciavillani R, Galli M
PMID: 33059408 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Emergency and regionalism in healthcare: challenges for the Italian National Health Service during COVID-19 pandemic.
Authors: Morana D
PMID: 33059409 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Marijuana influence on cardiac modulation and heart rate: novel hypotheses and gaps in evidence.
Authors: Iannaccone G, Porto I
PMID: 33059410 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Implantable loop recorder for syncope: essential tool or double-edged weapon?
Authors: Ebrille E, Crea P
PMID: 33059411 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 20, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Provisional stenting or not provisional stenting: seven critical points for bifurcations treatment with a glimpse on LM bifurcation stenting.
Authors: Iorio R, Cereda A, Vecchia A, Romagnoli E, Cioffi P, Chiricolo G, Sangiorgi G
Abstract
Stenting of coronary bifurcation lesions represents a challenge for the interventional cardiologist. A bifurcation lesion could be treated with several techniques. Therefore, it is of paramount importance to decide the strategical approach at the beginning of the procedure evaluating the patient's bifurcation anatomy, the angle between main and side branch, plaque burden at the level of the carina, and size of the side branch. Although it is clear that all bifurcation's treatment techniques have each one their a...
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Left ventricular concentric remodeling and impaired cardiorespiratory fitness in patients with heart failure and preserved ejection fraction.
CONCLUSIONS: Post-exercise reduced LV volumes correlate with measures of impaired CRF in patients with HFpEF, thus supporting a pathophysiologic role of concentric remodeling in impaired CRF in HFpEF.
PMID: 32996304 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Disentangling the epigenetic landscape in cardiovascular patients: a path toward personalized medicine.
Authors: Ambrosini S, Mohammed SA, Costantino S, Paneni F
Abstract
Despite significant advances in our understanding of cardiovascular disease (CVD) we are still far from having developed breakthrough strategies to combat coronary atherosclerosis and heart failure, which account for most of CV deaths worldwide. Available cardiovascular therapies have failed to show to be equally effective in all patients, suggesting that interindividual diversity is an important factor when it comes to conceive and deliver effective personalized treatments. Genome mapping has proved useful in identifying patients who could...
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Should different ECG-QRSd criteria be used for men and women with heart failure for cardiac resynchronization therapy?
Authors: Moti H
Abstract
In the present paper we review data of the efficacy of CRT based on baseline QRS duration and morphology in patients with heart failure due to left ventricle systolic dysfunction. We specifically review data that analyzed men and women separately. The main findings suggest benefit of CRT in patients with baseline LBBB, but not in patients without LBBB. Benefit is directly related to QRS duration at baseline with increasing rates and magnitude of echocardiographic response ( in terms of improvement in ejection fraction and decrease un LV size) and clinical response with increasing b...
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Cardiovascular effects of heat-not-burn and electronic-vaping-cigarettes in smokers.
Authors: Lombardi M, Nunes JP, Carbone S
PMID: 32996307 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Circulating VEGF and atherosclerosis risk: is it perhaps the case to reevaluate association with the inflammatory state?
Authors: Carrizzo A, Pagano F
PMID: 32996308 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Depression is associated with an increased risk of readmission in patients with heart failure: a systematic review and meta-analysis.
CONCLUSIONS: Our meta-analysis demonstrated that depression is associated with an increased risk of hospital readmission in patients with HF.
PMID: 32996309 [PubMed - as supplied by publisher] (Source: Minerva Cardioangiologica)
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
