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Antigen presentation capability and AP-1 activation accompany methotrexate-induced colon cancer cell senescence in the context of aberrant β-catenin signaling
Publication date: Available online 15 June 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Magdalena Dabrowska, Łukasz Uram, Michał Dabrowski, Ewa Sikora (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - June 16, 2021 Category: Geriatrics Source Type: research

Caloric restriction enhances vascular tone of cerebral and mesenteric resistance arteries in aged rats
Publication date: Available online 12 June 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Teresa Tropea, Maurizio Mandalà (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - June 14, 2021 Category: Geriatrics Source Type: research

Coenzyme Q10 supplementation – in ageing and disease
Publication date: Available online 12 June 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Jan Aaseth, Jan Alexander, Urban Alehagen (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - June 14, 2021 Category: Geriatrics Source Type: research

Sex-dependent monoamine oxidase isoforms expression patterns during human brain ageing
Publication date: Available online 5 June 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Cristina Sanfilippo, Paola Castrogiovanni, Rosa Imbesi, Giuseppe Lazzarino, Valentina Di Pietro, Giovanni Li Volti, Daniele Tibullo, Ignazio Barbagallo, Giacomo Lazzarino, Roberto Avola, Giuseppe Musumeci, Francesco Fazio, Manlio Vinciguerra, Michelino Di Rosa (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - June 5, 2021 Category: Geriatrics Source Type: research

No association between frailty index and epigenetic clocks in Italian semi-supercentenarians
Publication date: July 2021Source: Mechanisms of Ageing and Development, Volume 197Author(s): Maria Giulia Bacalini, Davide Gentilini, Daniela Monti, Paolo Garagnani, Daniela Mari, Matteo Cesari, Giulia Ogliari, Giuseppe Passarino, Claudio Franceschi, Chiara Pirazzini, Beatrice Arosio (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - June 5, 2021 Category: Geriatrics Source Type: research

Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm
Publication date: Available online 29 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Gabriella Teti, Francesca Chiarini, Eleonora Mazzotti, Alessandra Ruggeri, Francesco Carano, Mirella Falconi (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 30, 2021 Category: Geriatrics Source Type: research

A Role for Estrogen in Skin Ageing and Dermal Biomechanics
Publication date: Available online 25 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Holly N. Wilkinson, Matthew J. Hardman (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 26, 2021 Category: Geriatrics Source Type: research

NFKB2 inhibits NRG1 transcription to affect nucleus pulposus cell degeneration and inflammation in intervertebral disc degeneration
Publication date: Available online 21 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Xiaobin Wang, Hailin Wu, Qianshi Zhang, Fusheng Liu, Jingyu Wang, Chao Wei, Fubin Liu, Jing Li (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 21, 2021 Category: Geriatrics Source Type: research

Editorial Board
Publication date: June 2021Source: Mechanisms of Ageing and Development, Volume 196Author(s): (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 21, 2021 Category: Geriatrics Source Type: research

The old guard: age-related changes in microglia and their consequences
Publication date: Available online 19 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Jéssica Costa, Solange Martins, Pedro Ferreira, Ana M.S. Cardoso, Joana R. Guedes, João M. Peça, Ana L. Cardoso (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 20, 2021 Category: Geriatrics Source Type: research

New insights into molecular changes in skeletal muscle aging and disease: Differential alternative splicing and senescence
Publication date: Available online 19 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Elizaveta Solovyeva, Chikwendu Ibebunjo, Stephan Utzinger, John K. Eash, Andrew Dunbar, Ulrike Naumann, Yunyu Zhang, Fabrizio C. Serluca, Sabrina Demirci, Berndt Oberhauser, Frederique Black, Martin Rausch, Sebastian Hoersch, Angelika Meyer (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 19, 2021 Category: Geriatrics Source Type: research

Malnutrition is associated with poor trajectories of activities of daily living in geriatric rehabilitation inpatients: RESORT
Publication date: Available online 16 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Jeewanadee Hettiarachchi, Esmee M. Reijnierse, Cheng Hwee Soh, Bridget Agius, Kate Fetterplace, Wen Kwang Lim, Andrea Britta Maier (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 17, 2021 Category: Geriatrics Source Type: research

Long-term tobacco exposure and immunosenescence: paradoxical effects on T-cells telomere length and telomerase activity
Publication date: Available online 15 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Juliana Ruiz Fernandes, Thalyta Nery Carvalho Pinto, Lucas Lopes Piemonte, Liã Barbara Arruda, Cibele Cristine Berto Marques da Silva, Celso Ricardo Fernandes de Carvalho, Regina Maria Carvalho Pinto, Alberto José da Silva Duarte, Gil Benard (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 16, 2021 Category: Geriatrics Source Type: research

Progresses in both basic research and clinical trials of NAD+ in Parkinson’s disease
Publication date: Available online 11 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): María José Pérez, Pascale Baden, Michela Deleidi (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 12, 2021 Category: Geriatrics Source Type: research

Supplementation with phosphatidylethanolamine confers anti-oxidant and anti-aging effects via hormesis and reduced insulin/IGF-1-like signaling in C. elegans
Publication date: Available online 8 May 2021Source: Mechanisms of Ageing and DevelopmentAuthor(s): Suhyeon Park, Bo-Kyoung Kim, Sang-Kyu Park (Source: Mechanisms of Ageing and Development)
Source: Mechanisms of Ageing and Development - May 10, 2021 Category: Geriatrics Source Type: research