Optimal Use of Novel Agents in Chronic Lymphocytic Leukemia
(Source: Leukemia Research)
Source: Leukemia Research - May 7, 2018 Category: Hematology Authors: Mitchell R. Smith, Robert F. Weiss Source Type: research

High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ na ïve lymphocytes and prevents TTV reactivation
(Source: Leukemia Research)
Source: Leukemia Research - May 2, 2018 Category: Hematology Authors: Lorenzo Iovino, Francesco Mazziotta, Giovanni Carulli, Francesca Guerrini, Riccardo Morganti, Valentina Mazzotti, Fabrizio Maggi, Lisa Macera, Enrico Orciuolo, Gabriele Buda, Edoardo Benedetti, Francesco Caracciolo, Sara Galimberti, Mauro Pistello, Mario Tags: Meeting report Source Type: research

Shifting of Erythroleukemia to Myelodysplastic Syndrome according to the Revised WHO classification: Biologic and Cytogenetic features of Shifted Erythroleukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 28, 2018 Category: Hematology Authors: Sohee Ryu, Hee Sue Park, Sung-Min Kim, Kyongok Im, Jung-Ah Kim, Sang Mee Hwang, Sung-Soo Yoon, Dong Soon Lee Source Type: research

Corrigendum to ’CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia’ [leukemia research. 2018; 66: 15-19]
The authors regret that Lifang Huang and Miao Zheng contributed equally to this work and should be considered as co-first authors. (Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Authors: Jinjin Huang, Zhiqiong Wang, Lifang Huang, Miao Zheng Source Type: research

Editorial Board
(Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Source Type: research

Elevated miR-20b-5p expression in peripheral blood mononuclear cells: a novel, independent molecular biomarker of favorable prognosis in chronic lymphocytic leukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 26, 2018 Category: Hematology Authors: Sotirios G. Papageorgiou, Christos K. Kontos, Panagiotis Tsiakanikas, Georgia Stavroulaki, Anthi Bouchla, Diamantina Vasilatou, Efthymia Bazani, Afroditi Lazarakou, Andreas Scorilas, Vasiliki Pappa Tags: Research paper Source Type: research

High dose daunorubicin: New standard of care for FLT3 ITD mutant AML
Despite decades of use of cytarabine and anthracycline-based (7  + 3) chemotherapy as standard induction therapy for young patients with newly diagnosed AML, controversy regarding the specific anthracycline drug remains [1,2]. Is idarubicin or daunorubicin better? For which patients? At what dose? At many centers, the choice and dose of anthracycline depends upon patient age and/or institutional preference. Recently, however, the ability of clinicians to rapidly identify and delineate newly diagnosed AML patients based on specific mutational profiles has not only allowed for use of molecularly targeted agents (FLT3 and...
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Eunice S. Wang, Kristen O ’Dwyer Tags: Commentary Source Type: research

Phenotype variability of patients with post polycythemia vera and post essential thrombocythemia myelofibrosis is associated with the time to progression from polycythemia vera and essential thrombocythemia
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Barbara Mora, Toni Giorgino, Paola Guglielmelli, Elisa Rumi, Margherita Maffioli, Alessandro Rambaldi, Marianna Caramella, Rami Komrokji, Jason Gotlib, Jean Jacques Kiladjian, Francisco Cervantes, Timothy Devos, Francesca Palandri, Valerio De Stefano, Mar Tags: Letter to the Editor Source Type: research

High Dose Daunorubicin: New standard of care for FLT3 ITD mutant AML
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Eunice S. Wang, Kristen O ’Dwyer Tags: Commentary Source Type: research

Phenotype variability of patients with post polycythemia vera and post essential thrombocythemia myelofibrosis is associated with the time to progression from polycythemia vera and essential thrombocythemia
(Source: Leukemia Research)
Source: Leukemia Research - April 23, 2018 Category: Hematology Authors: Barbara Mora, Toni Giorgino, Paola Guglielmelli, Elisa Rumi, Margherita Maffioli, Alessandro Rambaldi, Marianna Caramella, Rami Komrokji, Jason Gotlib, Jean Jacques Kiladjian, Francisco Cervantes, Timothy Devos, Francesca Palandri, Valerio De Stefano, Mar Tags: Letter to the Editor Source Type: research

Monitoring of clonal evolution of double C-KIT exon 17 mutations by Droplet Digital PCR in patients with core-binding factor acute myeloid leukemia
(Source: Leukemia Research)
Source: Leukemia Research - April 22, 2018 Category: Hematology Authors: Yanhong Tan, Zhuang Liu, Wenjun Wang, Guiyang Zhu, Jianli Guo, Xiuhua Chen, Chaofeng Zheng, Zhifang Xu, Jianmei Chang, Fanggang Ren, Hongwei Wang Tags: Research paper Source Type: research

Chinese and Europeans with Acute Myeloid Leukemia Have Discordant Mutation Topographies
(Source: Leukemia Research)
Source: Leukemia Research - April 21, 2018 Category: Hematology Authors: Min Zhang, Jiawei Yin, Qinghua He, Fan Zhang, Hongyu Huang, Biao Wu, Xuedong Wang, Hong Liu, Hongchao Yin, Yan Zeng, Robert Peter Gale, Depei Wu, Bin Yin Source Type: research

Associations of myeloid hematological diseases of the elderly with osteoporosis: A longitudinal analysis of routine health care data
With 27.5 million patients in Europe osteoporosis (OSP) is one of the most frequently occurring disorders in elderly people leading to an increased risk of fractures and falls due to progressive loss of bone strength [1]. 3.5 million incident fractures, possibly related to OSP, were estimated for the year 2010 [1] in Europe. Myelodysplastic syndromes (MDS) represent a group of common hematological malignancies of the elderly caused by heterogeneous clonal disorders of hematopoietic stem and progenitor cells (HSPC). (Source: Leukemia Research)
Source: Leukemia Research - April 20, 2018 Category: Hematology Authors: Thomas Datzmann, Freya Trautmann, Falko Tesch, Anna Mies, Lorenz C. Hofbauer, Uwe Platzbecker, Jochen Schmitt Tags: Research paper Source Type: research