Increased vasohibin-1 expression is associated with metastasis and poor prognosis of renal cell carcinoma patients
nori Okada (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Shuji Mikami Mototsugu Oya Takeo Kosaka Ryuichi Mizuno Yasumasa Miyazaki Yasufumi Sato Yasunori Okada Source Type: research

The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals
& Haibo Bai (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Nan Wu Quy Nguyen Ying Wan Tiaohao Zhou Julie Venter Gabriel A Frampton Sharon DeMorrow Duojia Pan Fanyin Meng Shannon Glaser Gianfranco Alpini Haibo Bai Source Type: research

Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis
hi Yokoi (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Yuji Shirai Shingo Oda Sayaka Makino Koichi Tsuneyama Tsuyoshi Yokoi Source Type: research

Hedgehog signaling pathway affects the sensitivity of hepatoma cells to drug therapy through the ABCC1 transporter
Jian Wu (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Jia Ding Xiao-Tian Zhou Hao-Yu Zou Jian Wu Source Type: research

Endothelial cell-specific activation of transforming growth factor- β signaling in mice induces cutaneous, visceral, and microvascular fibrosis
Endothelial cell-specific activation of transforming growth factor-β signaling in mice induces cutaneous, visceral, and microvascular fibrosis Laboratory Investigation 97, 806 (July 2017). doi:10.1038/labinvest.2017.23 Authors: Peter J Wermuth, Kellan R Carney, Fabian A Mendoza, Sonsoles Piera-Velazquez & Sergio A Jimenez (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Peter J Wermuth Kellan R Carney Fabian A Mendoza Sonsoles Piera-Velazquez Sergio A Jimenez Source Type: research

Advanced oxidation protein products promote NADPH oxidase-dependent β -cell destruction and dysfunction through the Bcl-2 / Bax apoptotic pathway
Advanced oxidation protein products promote NADPH oxidase-dependent β-cell destruction and dysfunction through the Bcl-2/Bax apoptotic pathway Laboratory Investigation 97, 792 (July 2017). doi:10.1038/labinvest.2017.24 Authors: Min Liang, Aiqing Li, Aiju Lou, Xifang Zhang, Youyuan Chen, Lei Yang, Yumin Li, Shenglin Yang & Fan Fan Hou (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Min Liang Aiqing Li Aiju Lou Xifang Zhang Youyuan Chen Lei Yang Yumin Li Shenglin Yang Fan Fan Hou Source Type: research

Cytochrome P450 (CYP) epoxygenases as potential targets in the management of impaired diabetic wound healing
p; Yuantao Liu (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Huichen Zhao Jicui Chen Jiachao Chai Yuchao Zhang Cong Yu Zhe Pan Peng Gao Chen Zong Qingbo Guan Yuqin Fu Yuantao Liu Source Type: research

Disruption of direct 3D telomere – TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed – Sternberg cells
Disruption of direct 3D telomere–TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed–Sternberg cells Laboratory Investigation 97, 772 (July 2017). doi:10.1038/labinvest.2017.33 Authors: Hans Knecht, Nathalie A Johnson, Tina Haliotis, Daniel Lichtensztejn & Sabine Mai (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Hans Knecht Nathalie A Johnson Tina Haliotis Daniel Lichtensztejn Sabine Mai Source Type: research

Angiotensin-converting enzyme affects the presentation of MHC class II antigens
Z Shen (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Authors: Tuantuan Zhao Kenneth E Bernstein Jianmin Fang Xiao Z Shen Source Type: research

Malignant melanoma: from cause to cure
Laboratory Investigation 97, 762 (July 2017). doi:10.1038/labinvest.2017.58 (Source: Laboratory Investigation)
Source: Laboratory Investigation - June 30, 2017 Category: Laboratory Medicine Source Type: research

The biological and prognostic significance of angiotropism in uveal melanoma
; Claire Lugassy (Source: Laboratory Investigation)
Source: Laboratory Investigation - May 26, 2017 Category: Laboratory Medicine Authors: Raymond L Barnhill Mengliang Ye Aude Batistella Marc-Henri Stern Sergio Roman-Roman R é mi Dendale Olivier Lantz Sophie Piperno-Neumann Laurence Desjardins Nathalie Cassoux Claire Lugassy Source Type: research

Adipogenic niches for melanoma cell colonization and growth in bone marrow
Cheng Qian (Source: Laboratory Investigation)
Source: Laboratory Investigation - May 26, 2017 Category: Laboratory Medicine Authors: Juan Wang Guang-liang Chen Shan Cao Ming-chun Zhao Yong-qing Liu Xiao-Xiang Chen Cheng Qian Source Type: research

Notch3 signaling-mediated melanoma – endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis
Notch3 signaling-mediated melanoma–endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis Laboratory Investigation 97, 725 (June 2017). doi:10.1038/labinvest.2017.1 Authors: Mei-Yu Hsu, Moon Hee Yang, Caroline I Schnegg, Soonyean Hwang, Byungwoo Ryu & Rhoda M Alani (Source: Laboratory Investigation)
Source: Laboratory Investigation - May 26, 2017 Category: Laboratory Medicine Authors: Mei-Yu Hsu Moon Hee Yang Caroline I Schnegg Soonyean Hwang Byungwoo Ryu Rhoda M Alani Source Type: research

Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
mp; Craig A Elmets (Source: Laboratory Investigation)
Source: Laboratory Investigation - May 26, 2017 Category: Laboratory Medicine Authors: Andrzej T Slominski Anna A Bro ż yna Michal A Zmijewski Wojciech J ó ź wicki Anton M Jetten Rebecca S Mason Robert C Tuckey Craig A Elmets Source Type: research

Mouse models of UV-induced melanoma: genetics, pathology, and clinical relevance
Michael (Source: Laboratory Investigation)
Source: Laboratory Investigation - May 26, 2017 Category: Laboratory Medicine Authors: Chi-Ping Day Rachel Marchalik Glenn Merlino Helen Michael Source Type: research