Supplementation of Specific Carbohydrates Results in Enhanced Deposition of Chondrogenic ‐Specific Matrix during Mesenchymal Stem Cell Differentiation
Abstract Repair or regeneration of hyaline cartilage in knees, shoulders, intervertebral discs and other assorted joints is a major therapeutic target. To date, therapeutic strategies utilizing chondrocytes or mesenchymal stem cells are limited by expandability or the generation of mechanically inferior cartilage. Our objective is to generate robust cartilage‐specific matrix from human mesenchymal stem cells suitable for further therapeutic development. Human mesenchymal stem cells, in an alginate 3D format, were supplied with individual sugars and chains which comprise the glycan component of proteoglycans in articular ...
Source: Journal of Tissue Engineering and Regenerative Medicine - February 1, 2018 Category: Biotechnology Authors: Trudy Christiansen ‐Weber, Alexander Noskov, Dylan Cardiff, Ibon Garitaonandia, Alexa Dillberger, Andrey Semechkin, Rodolfo Gonzalez, Russell Kern Tags: RESEARCH ARTICLE Source Type: research

The roles of cellular and molecular components of a hematoma at early stage of bone healing
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 31, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 31, 2018 Category: Biotechnology Source Type: research

Development of lacrimal gland spheroids for lacrimal gland tissue regeneration
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 29, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 29, 2018 Category: Biotechnology Source Type: research

Segregation of motor and sensory axons regenerating through bicompartmental tubes by combining extracellular matrix components with neurotrophic factors
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 28, 2018 Category: Biotechnology Source Type: research

A review on gradient hydrogel/fiber scaffolds for osteochondral regeneration
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 28, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 28, 2018 Category: Biotechnology Source Type: research

Issue Information
No abstract is available for this article. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 26, 2018 Category: Biotechnology Tags: ISSUE INFORMATION Source Type: research

Cover Image, Volume 12, Issue 1
The cover image, by I. Stefani et al., is based on the Research Article A double chamber rotating bioreactor for enhanced tubular tissue generation from human mesenchymal stem cells: a promising tool for vascular tissue regeneration, DOI: 10.1002/term.2341. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 26, 2018 Category: Biotechnology Authors: I. Stefani, M.A. Asnaghi, J.J. Cooper ‐White, S. Mantero Tags: COVER IMAGE Source Type: research

Generation of full ‐thickness skin equivalents using hair follicle‐derived primary human keratinocytes and fibroblasts
SUMMARY Skin equivalents are increasingly used as human‐based test systems for basic and preclinical research. Most of the established skin equivalents are composed of primary keratinocytes and fibroblasts, isolated either from excised human skin or juvenile foreskin following circumcisions. Although the potential of hair follicle‐derived cells for the generation of skin equivalents has been shown, this approach normally requires microdissections from the scalp for which there is limitted subject compliance or ethical approval. In the present study, we report a novel method to isolate and cultivate keratinocytes and fi...
Source: Journal of Tissue Engineering and Regenerative Medicine - January 26, 2018 Category: Biotechnology Authors: Anna L öwa, Annika Vogt, Sabine Kaessmeyer, Sarah Hedtrich Tags: RESEARCH ARTICLE Source Type: research

Biomimetic fetal rotation bioreactor for engineering bone tissues —Effect of cyclic strains on upregulation of osteogenic gene expression
Journal of Tissue Engineering and Regenerative Medicine, EarlyView. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 25, 2018 Category: Biotechnology Source Type: research

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Journal of Tissue Engineering and Regenerative Medicine, Ahead of Print. (Source: Journal of Tissue Engineering and Regenerative Medicine)
Source: Journal of Tissue Engineering and Regenerative Medicine - January 25, 2018 Category: Biotechnology Source Type: research