Integration of rare cell capture technology into cytologic evaluation of cerebrospinal fluid specimens from patients with solid tumors and suspected leptomeningeal metastasis
ConclusionsIn this proof-of-principle pilot study, we demonstrate that the CellSearch assay can be successfully integrated with the routine CSF cytologic workflow to aid in the diagnosis of solid tumor LM. Importantly, CTCs detected by this rare cell capture assay are found in a subset of patients with non-positive routine CSF cytology, which may have significant implications for patient management. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - September 12, 2019 Category: Cytology Source Type: research

Results from the 2019 American Society of Cytopathology survey on rapid on-site evaluation—Part 1: objective practice patterns
ConclusionsThe results from our survey of cytologists have shown that the reported practice patterns for the usage of ROSE vary considerably. The presented data can help inform future guideline recommendations and the implementation of ROSE in different clinical settings. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - September 6, 2019 Category: Cytology Source Type: research

Role of cytotechnologists in rapid onsite adequacy assessment of cytology materials for diagnostic workup and specimen allocation for ancillary testing using a standardized protocol
Publication date: Available online 21 August 2019Source: Journal of the American Society of CytopathologyAuthor(s): Russel Fetzer, Michelle Duey, Valerie Pena, Dana Wanzer, James Kirkpatrick, Donnie Chau, Venetia R. SarodeAbstractIntroductionData on the performance of cytotechnologists in assessing specimen adequacy of needle core biopsies (NCB) is scant and their role in specimen triaging for ancillary studies have not been well established.Materials and methodsWe retrospectively analyzed ROSE performed exclusively by cytotechnologists on 248 NCB and fine needle aspiration (FNA) specimens. Overall adequacy and accuracy ra...
Source: Journal of the American Society of Cytopathology - August 22, 2019 Category: Cytology Source Type: research

Utility of Subcategorization of Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Category in Ultrasound-Guided Thyroid Fine-Needle Aspiration in a Large Referral Cancer Center
ConclusionsSubclassification of AUS/FLUS into three groups based on cytopathologic findings alone not only improved the triage of patients for subsequent clinical management but also effectively stratified the risk of malignancy. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - August 21, 2019 Category: Cytology Source Type: research

Invasive cervical cancer after treatment of CIN
ConclusionsResidual disease may be inconspicuous or absent on cytology, colposcopy and/or histology. Management taking account of risk of recurrence (age, CIN3 depth, incomplete initial excision) could avoid some post-treatment cancers. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - August 18, 2019 Category: Cytology Source Type: research

It is all in the bag: collodion bag versus HistoGel cell block method
ConclusionsThe collodion bag method produced superior cell blocks for both morphologic and molecular studies more consistently, with lower volume specimens and with less time per specimen.Graphical abstract (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - August 15, 2019 Category: Cytology Source Type: research

Granulomatous Inflammation Diagnosed by Fine Needle Aspiration Biopsy
Publication date: Available online 14 August 2019Source: Journal of the American Society of CytopathologyAuthor(s): Dianna L. Ng, Ronald BalassanianAbstractIntroductionFine needle aspiration biopsy (FNAB) is a minimally invasive biopsy technique and is an important tool for diagnosing infectious diseases. Rapid on-site evaluation allows for triage for ancillary testing, including microbiologic cultures. We aim to determine the etiology of granulomatous inflammation diagnosed by FNAB by correlating with culture results and clinical history.Materials and methodsA 16-year retrospective review of cases diagnosed as “gran...
Source: Journal of the American Society of Cytopathology - August 15, 2019 Category: Cytology Source Type: research

Results from the 2019 American Society of Cytopathology Survey on Rapid On-Site Evaluation (ROSE). Part 1: Objective practice patterns
ConclusionsBased on the results of this survey of cytologists, the reported practice patterns for the utilization of ROSE vary considerably. The data presented here can help inform future guideline recommendations and the implementation of ROSE in different clinical settings. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - August 9, 2019 Category: Cytology Source Type: research

Cytologic Processing of Ureteral Microbiopsies is Associated with Higher Sensitivity for Detection of Urothelial Carcinoma Compared to Conventional Biopsy Processing
ConclusionsCytologic processing of ureteral microbiopsies shows superior sensitivity for detecting HGUC, apparently due to increased cellular recovery. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - August 9, 2019 Category: Cytology Source Type: research

Proceedings of the American Society of Cytopathology Companion Session at the 2019 United States and Canadian Academy of Pathology Annual Meeting, Part 2: Effusion cytology with focus on Theranostics and Diagnosis of Malignant Mesothelioma
Publication date: Available online 8 August 2019Source: Journal of the American Society of CytopathologyAuthor(s): Momin T. Siddiqui, Fernando Schmitt, Andrew ChurgAbstractWe live in the “era” of minimally invasive procedures, molecular testing and personalized care. Effusions have a high sensitivity and often yield diagnostic cytological material. This companion session presented by the American Society of Cytopathology at the 2019 USCAP meeting outlined our current and future projected practices in characterizing, handling and diagnosing serous cavity fluids, and in this second part, the role of theranostics ...
Source: Journal of the American Society of Cytopathology - August 9, 2019 Category: Cytology Source Type: research

Insulinoma-associated protein 1 is a sensitive and specific marker for lung neuroendocrine tumors in cytologic and surgical specimens
ConclusionsThe results from our study have further established the high sensitivity and specificity of INSM1 in the largest pulmonary cytologic and surgical cohorts to date. INSM1 either matched or outperformed the performance of existing neuroendocrine markers, and its combination with CD56 appeared to maximize test performance. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 24, 2019 Category: Cytology Source Type: research

Eye tracking in cytotechnology education: “Visualizing” students becoming experts
ConclusionsThis study demonstrated that students had decreased time, number of fixation points, gaze observations on ROI, and increased agreement with the reference interpretations at the end of the training program, indicating that their screening skills were progressing towards the level of practicing cytotechnologists. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 11, 2019 Category: Cytology Source Type: research

It’s all in the Bag: Collodion Bag Versus HistoGel Cell Block Method
ConclusionsThe collodion bag method produced superior cell blocks for both morphologic and molecular studies more consistently, with lower volume specimens and with less time per specimen.Graphical abstract (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 6, 2019 Category: Cytology Source Type: research

Significance of Atypical Endometrial Cells in Women Younger than 40 Years of Age
ConclusionsOur study suggests that it is important to recognize the presence of atypical endometrial cells in Pap tests in young patients, given its association with the finding of premalignant and malignant pathology in the subsequent endometrial biopsies. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 6, 2019 Category: Cytology Source Type: research

Table of contents
Publication date: July–August 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 4Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 2, 2019 Category: Cytology Source Type: research

Editorial Board
Publication date: July–August 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 4Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - July 2, 2019 Category: Cytology Source Type: research

Self-collected Papanicolaou tests in the United States market: more questions than answers
Publication date: Available online 27 May 2019Source: Journal of the American Society of CytopathologyAuthor(s): Paul N. Staats, Christine N. Booth, Dorothy L. Rosenthal, Barbara A. CrothersThe United States Food and Drug Administration held a public hearing in January 2018 to consider how it should evaluate a self-collection device for cervical cytology. Although no such device has been approved for use in the US market, the implications for patients and cytologists could be both sweeping and complex. Herein, the existing literature basis for self-collected Papanicolaou testing is reviewed, and some questions raised by th...
Source: Journal of the American Society of Cytopathology - June 28, 2019 Category: Cytology Source Type: research

Insulinoma-associated protein 1 (INSM1) is a Sensitive and Specific Marker for Lung Neuroendocrine Tumors in Cytologic and Surgical Specimens
ConclusionsOur study further establishes high sensitivity and specificity of INSM1 in the largest pulmonary cytologic and surgical cohorts to date. INSM1 either matches or outperforms existing neuroendocrine markers and in combination with CD56 appears to maximize test performance. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - June 26, 2019 Category: Cytology Source Type: research

A Review Of The Fda-Approved Molecular Testing Platforms For Human Papillomavirus
Publication date: Available online 13 June 2019Source: Journal of the American Society of CytopathologyAuthor(s): Katrina L. Salazar, Daniel J. Duhon, Randall Olsen, Michael Thrall (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - June 15, 2019 Category: Cytology Source Type: research

The Color of Urine: Then and now - A Comprehensive Review of the Literature with Emphasis on Intracytoplasmic Pigments Encountered in Urinary Cytology
We present a review of the significance of pigmented cells in urine cytology. The presence of intracellular pigment granules, their color, size, shape and variation in size and shape, as well as their staining reactions with special stains can provide useful diagnostic insight, especially when interpreted in the cytologic context (type of pigmented cell and its degree of atypicality) and patient’s clinical context. The main differential diagnosis of cytoplasmic pigmented granules includes hemosiderin, lipofuscin, and melanin, each having a different pathogenesis and significance. The goal of this manuscript is to des...
Source: Journal of the American Society of Cytopathology - June 14, 2019 Category: Cytology Source Type: research

Role of ThinPrep liquid-based cytology in evaluation of the endocervical canal in patients with abnormal cervical screening
ConclusionsTP LBC is capable of detecting endocervical epithelial abnormalities and may be used as a substitute for endocervical curettings. Performing a CB did not lead to detection of additional abnormalities, although it complemented TP findings and facilitates the performance of ancillary studies. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - June 9, 2019 Category: Cytology Source Type: research

Self-Collected Pap Tests in the United States Market: More Questions Than Answers
Publication date: Available online 27 May 2019Source: Journal of the American Society of CytopathologyAuthor(s): Paul N. Staats, Christine N. Booth, Dorothy L. Rosenthal, Barbara A. CrothersAbstractThe United States Food and Drug Administration (FDA) held a public hearing in January 2018 to consider how the FDA should evaluate a self-collection device for cervical cytology. While no such device has been approved for use in the US market, the implications for patients and cytologists could be both sweeping and complex. Herein, the existing literature basis for self-collected Pap testing is reviewed, and some questions raise...
Source: Journal of the American Society of Cytopathology - May 29, 2019 Category: Cytology Source Type: research

Role of ThinPrep® liquid-based cytology in evaluation of the endocervical canal in patients with abnormal cervical screening
ConclusionsTP LBC is capable of detecting endocervical epithelial abnormalities and may be used as a substitute for ECC. Performing a CB did not lead to detection of additional abnormalities, although it complemented TP findings and facilitates the performance of ancillary studies. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 18, 2019 Category: Cytology Source Type: research

Mucoepidermoid carcinoma, acinic cell carcinoma, and adenoid cystic carcinoma on fine-needle aspiration biopsy and The Milan System: an international multi-institutional study
ConclusionsThe DA of 78.7% for MECa, 75% for ACCa, and 89% for ADCa is reasonable in FNA specimens. Although the management of definitive cases of malignancy remains unchanged, the MSRSGC provides a ROM for SM and SUMP categories, which can improve patient management. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 17, 2019 Category: Cytology Source Type: research

Table of contents
Publication date: May–June 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 3Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 14, 2019 Category: Cytology Source Type: research

Erratum to New Quantitative Data on Cell Blocks. Journal of the American Society of Cytopathology Volume 8, Issue 2, March–April 2019, Pages 49-51
Publication date: May–June 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 3Author(s): Andrew H. Fischer (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 14, 2019 Category: Cytology Source Type: research

Editorial Board
Publication date: May–June 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 3Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 14, 2019 Category: Cytology Source Type: research

Diagnostic yield of the SharkCore EUS-guided fine-needle biopsy
ConclusionsSC-FNB shows high diagnostic yield and accuracy and provides diagnostic tissue for ROSE. SC-FNB is an effective alternative to conventional FNA. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - May 8, 2019 Category: Cytology Source Type: research

Comparison of the collection approaches of 2 large thyroid fine-needle aspiration practices reveals differing advantages for cytology and molecular testing adequacy rates
In this study, we compared the cytology and molecular adequacy rates of these 2 thyroid FNA practices, which differ on several aspects of specimen procurement.Materials and methodsAll thyroid FNA specimens from Endocrinology and Radiology practices between September 2008 and December 2016 were included. Over this time frame, the molecular testing modality transitioned from polymerase chain reaction (PCR)-based (7-gene panel era) to next generation sequencing (NGS)-based (ThyroSeq era). In measuring cytology adequacy, the Bethesda System unsatisfactory rate was determined. Molecular adequacy was categorized as Optimal, Limi...
Source: Journal of the American Society of Cytopathology - April 30, 2019 Category: Cytology Source Type: research

Reactivity with the EpCAM-specific Antibodies MOC-31 and Ber-Ep4 in Plasma Cell Neoplasms: A Potential Diagnostic Pitfall in Cytology Samples
Publication date: Available online 18 April 2019Source: Journal of the American Society of CytopathologyAuthor(s): Cody Weimholt (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - April 18, 2019 Category: Cytology Source Type: research

Mucoepidermoid Carcinoma, Acinic Cell Carcinoma, and Adenoid Cystic Carcinoma on Fine Needle Aspiration Biopsy and Milan System: An International Multi-Institutional Study
ConclusionThe DA of 78.7% for MECa, 75% for ACCa, and 89% for ADCa is reasonable in FNA specimens. While the management of definitive cases of malignancy remains unchanged, the MSRSGC provides a ROM for SM and SUMP categories, which can improve the patient management. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - April 9, 2019 Category: Cytology Source Type: research

Comparison of the Collection Approaches of Two Large Thyroid Fine Needle Aspiration Practices Reveals Differing Advantages for Cytology and Molecular Testing Adequacy Rates
In this study, we compared the cytology and molecular adequacy rates of these two thyroid FNA practices, which differ on several aspects of specimen procurement.Materials and MethodsAll thyroid FNA specimens from Endocrinology and Radiology practices between September 2008 and December 2016 were included. Over this time frame, the molecular testing modality transitioned from polymerase chain reaction (PCR)-based (7-gene panel era) to Next Generation Sequencing (NGS)-based (ThyroSeq era). In measuring cytology adequacy, the Bethesda System unsatisfactory rate was determined. Molecular adequacy was categorized as Optimal, Li...
Source: Journal of the American Society of Cytopathology - April 4, 2019 Category: Cytology Source Type: research

The impact of primary HPV screening on the incidence of cervical cancer in New Zealand
ConclusionsThe results indicate that lengthening the screening interval concurrently with changing to HPV testing may reduce the protection from invasive cervical cancer for women. Women in New Zealand should continue to be screened by cytology every 3 years. Changes to screening policy should be carefully designed so that changes in screening effectiveness can be accurately measured. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - March 30, 2019 Category: Cytology Source Type: research

A small-scale experimental study of breast FNA consultation on the internet using Panoptiq
ConclusionsOur small-scale experimental study, in which Panoptiq was used in the diagnosis of cases that were difficult to diagnose definitively by breast FNA, revealed a positive CB score by every reviewer and the representative diagnosis showed a significant CB. The study suggests that Panoptiq could be used for cytopathology consultation. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - March 29, 2019 Category: Cytology Source Type: research

Artificial Intelligence in Cytopathology: A Review of the Literature and Overview of Commercial Landscape
Publication date: Available online 25 March 2019Source: Journal of the American Society of CytopathologyAuthor(s): Michael S. Landau, Liron PantanowitzAbstractArtificial Intelligence (AI) has made impressive strides recently in interpreting complex images, thanks to improvements in deep learning techniques and increasing computational power. Researchers have started applying these advanced techniques to pathology images, although most efforts have been focused on histopathology. Cytopathology, however, remains the original field of pathology for which AI models for clinical use were successfully commercialized, to assist w...
Source: Journal of the American Society of Cytopathology - March 26, 2019 Category: Cytology Source Type: research

Biphasic Chest wall Synovial Sarcoma with Epithelial Pleural Effusion: A Diagnostic Challenge
Publication date: Available online 18 March 2019Source: Journal of the American Society of CytopathologyAuthor(s): Hoda Zeinab M. Amer, Rongqin Ren, Rulong Shen (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - March 18, 2019 Category: Cytology Source Type: research

Fine-needle aspiration specimens of 3 cases of intra-abdominal Rosai-Dorfman disease with comprehensive review of the literature
ConclusionOur experience and an extensive review of the literature suggest that extranodal RDD can be diagnosed on FNA, and that the recognition of histiocytes with emperipolesis may be less challenging cytologically than histologically. The fibrosis frequently seen in extranodal RDD may lead to nondiagnostic aspirates, however. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - March 12, 2019 Category: Cytology Source Type: research

Diagnostic yield of the SharkCoreTM EUS-guided fine biopsy needle
ConclusionsSC-FNB shows high diagnostic yield and accuracy and provides diagnostic tissue for ROSE. SC-FNB is an effective alternative to the conventional FNA. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - March 12, 2019 Category: Cytology Source Type: research

Nationwide survey of cervical cytology laboratory practices in China
ConclusionAbnormal cytology rates were not significantly different when different levels of hospitals were compared. The survey identified nationwide opportunities for cytology quality improvement, including low rates of reporting of unsatisfactory cases and low rates for atypical glandular cells. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 22, 2019 Category: Cytology Source Type: research

Diagnostic utility of fluorescence in situ hybridization testing on cytology cell blocks for the definitive classification of salivary gland neoplasms
ConclusionsFISH testing performed on cytology cell blocks is a useful adjunct in establishing the diagnosis of salivary gland neoplasms by FNAB. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 17, 2019 Category: Cytology Source Type: research

Fine needle aspiration diagnosis of metastatic Leydig cell tumor. Report of a case and review of the literature
Publication date: Available online 16 February 2019Source: Journal of the American Society of CytopathologyAuthor(s): John Biemer, Stefan E. Pambuccian, Güliz A. BarkanAbstractLeydig cell tumors are rare sex cord-stromal tumors that account for less than 1% of all testicular tumors. Less than 10% of these tumors show metastatic malignant behavior.Herein we present a case of metastatic malignant Leydig cell tumor in an iliac lymph node diagnosed on fine-needle aspiration (FNA) in a 70-year-old man. The patient was referred from an outside institution with lymphadenopathy and had a past medical history of lymphoplasmacy...
Source: Journal of the American Society of Cytopathology - February 17, 2019 Category: Cytology Source Type: research

Editorial Board
Publication date: March–April 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 2Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 9, 2019 Category: Cytology Source Type: research

Table of contents
Publication date: March–April 2019Source: Journal of the American Society of Cytopathology, Volume 8, Issue 2Author(s): (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 9, 2019 Category: Cytology Source Type: research

Previous Papanicolaou and Hybrid Capture 2 human papillomavirus testing results of 5699 women with histologically diagnosed cervical intraepithelial neoplasia 2/3
ConclusionsThe present study has reported the previous results of HPV testing and Pap cytology for patients with high-grade cervical squamous precursor lesions in a population of women in China who had not undergone intensive previous screening. Both high-risk HPV and Pap cytology had similar negative testing rates for these women, although double negative results were less common. These results support the value of combined testing in the detection of cervical cancer precursors. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 8, 2019 Category: Cytology Source Type: research

Fine-Needle Aspiration Specimens of Three Cases of Intraabdominal Rosai-Dorfman Disease with Comprehensive Review of the Literature
ConclusionOur experience and an extensive review of the literature suggest that extranodal RDD can be diagnosed on FNA, and that the recognition of histiocytes with emperipolesis may be less challenging cytologically than histologically. However, the fibrosis frequently seen in extranodal RDD may lead to nondiagnostic aspirates. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - February 5, 2019 Category: Cytology Source Type: research

Implementing the Papanicolaou Society of Cytopathology Terminology System for reporting pancreaticobiliary cytology refines risk of malignancy in pancreatic specimens
Publication date: Available online 30 January 2019Source: Journal of the American Society of CytopathologyAuthor(s): Mauro Saieg (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - January 30, 2019 Category: Cytology Source Type: research

Diagnostic value of imprint cytology testing in kidney tumors: review of 200 cases
ConclusionsThe relatively low diagnostic value of IC testing for renal tumors showed it to be less powerful for screening than its use in other organs. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - January 28, 2019 Category: Cytology Source Type: research

Diagnostic Utility of Fluorescence in Situ Hybridization (FISH) Testing on Cytology Cell Blocks for the Definitive Classification of Salivary Gland Neoplasms
ConclusionsIn summary, FISH testing performed on cytology cell blocks is a useful adjunct in establishing the diagnosis of salivary gland neoplasms by FNAB. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - January 26, 2019 Category: Cytology Source Type: research

Incidence of noninvasive follicular thyroid neoplasm with papillary-like nuclear features and change in risk of malignancy for The Bethesda System for Reporting Thyroid Cytology
ConclusionIn our institution, NIFTP accounts for 13% of all malignant thyroid neoplasms since the NC. While ROM decreases in affected categories - absolute statistically significant decreases in ROM are 15% and 16.2% for categories III and IV, respectively, - the overall ROM change is marginal. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - January 23, 2019 Category: Cytology Source Type: research

Prior PAP and HC2 HPV testing results of 5699 women with histologically diagnosed cervical intraepithelial neoplasia 2/3
ConclusionThis study demonstrates prior results of HPV testing and PAP cytology for patient with high grade cervical squamous precursor lesions in a population of women in China who had not undergone intensive prior screening. Both hrHPV and PAP cytology had similar negative testing rates for these women but double negative results were less common. These results support the value of co-testing in the detection of cervical cancer precursors. (Source: Journal of the American Society of Cytopathology)
Source: Journal of the American Society of Cytopathology - January 18, 2019 Category: Cytology Source Type: research