Editorial - Autologous Bone Marrow Transplantations in Neurological Disorders.
Authors: Bansal H
PMID: 28296859 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Evaluation of Bone Marrow Processing Protocol for Therapeutic Applications via Culture and Characterization of Mesenchymal Stem Cells.
Conclusion: MSCs from the bone marrow were isolated and differentiated. These cells were morphologically healthy and passed CFU assay. The cells exhibited differentiation potential into bone, fat and neural tissue. These cells can be used in therapeutic applications.
PMID: 28296860 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Therapy with Bone Marrow-Derived Autologous Adult Stem Cells in Quadriparesis due to Motor Neuron Disease.
Conclusion: The local application of a cocktail of regenerative cell population found in an MNC fraction of bone marrow was safe and effective in improving quality of life and muscle strength in ALS patients. This case opens the need for further investigations on Autogenic stem cell transplant therapies for MND disease.
PMID: 28296861 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
A Short Study Report on Bone Marrow Aspirate Concentrate Cell Therapy in Ten South Asian Indian Patients with Autism.
We report promising results in this small pilot study using autologous Bone Marrow Aspirate Concentrate (BMAC) injected intrathecally into these ten enrolled autistic patients.
PMID: 28296862 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Administration of Autologous Bone Marrow-Derived Stem Cells for Treatment of Cerebral Palsy Patients: A Proof of Concept.
Conclusion: Our results indicated that bone marrow derived MNCs are safe and effective for the treatment of motor deficits related to cerebral palsy. Further randomized clinical trials are necessary to establish the efficacy of this procedure.
PMID: 28296863 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Autologous Bone Marrow-Derived Stem Cells in Spinal Cord Injury.
Conclusion: This preliminary proof of patient improvement reinforces the potential of autologous bone marrow stem cell treatment in the patients suffering from Spinal Cord Injury. Although the results are encouraging further studies are needed to substantiate the claims.
PMID: 28296864 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Revisiting Terminology and Characteristics of Stem Cells.
Authors: Pechersky AV
Abstract
The majority of populations of differentiated cells are subject to renewal. Progenitor cells (cells-predecessors) and differentiated cells, having started the differentiation pathway or having finished it, can divide a limited number of times and are not capable of ensuring tissue regeneration during the whole period of ontogenesis. Renewal of tissues over such a long period is impossible without the participation of a specialized system which is responsible for regeneration. The given system is represented by pluripotent stem cells. Pluripotent stem cells, which conduct rege...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Immune System and Regeneration.
Authors: Pechersky AV, Pechersky VI, Aseev MV, Droblenkov AV, Semiglazov VF
Abstract
The review article is devoted to a role of pluripotent stem cells and immune system in renewal of tissues (regeneration). Cell-precursors (progenitor cells) and differentiated cells can be divided a limited number of times and aren't capable of ensuring regeneration of tissues during the whole process of ontogenesis. The renewal of tissues during the whole long period is impossible without the participation of a specialized system which is responsible for regeneration. The given system is made up of pluripotent stem cells ...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Regeneration and Cicatrization.
Authors: Pechersky AV, Pechersky VI, Shpilenya ES, Gaziev AH, Semiglazov VF
Abstract
Cicatricial tissue, being the local center of sclerosis, replaces the wound or focus of cell death. Scarring is caused by various types of injuries, including operations, as well as by a number of diseases. Scarring often culminates in the formation of strictures and other complications. Integrated stimulation of regeneration that takes the role of the immune system into account, in conjunction with the prescription of enzyme preparations possessing proteolytic activity, can be used to reduce the severity of sclerosis of d...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Influence of Violation of Regeneration in People over 35-40 Years Old on Decrease in Production of Sexual Hormones.
Authors: Pechersky AV
Abstract
With age the quantity of pluripotent stem cells gradually decreases. It leads to violation of renewal of tissues, including tissues of endocrine organs, at people over 35-40 years old. Artificial formation of the chimeral individual may be used for recovery of the pool of pluripotent stem cells in patients older than 40-50 years old. Transfusions of mononuclear fraction of peripheral blood procured from young donors 18-23 years old with the same blood groups and sex as the recipient (patent of the Russian Federation № 2350340), allows people over 40 years old to reestablish...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Editorial - Mesenchymal Stem Cells in Androgenic Alopecia: Hair Loss Regeneration.
Authors: Koka PS
PMID: 28296869 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Platelet-Rich Plasma Growth Factor Concentrated Spray (Keratogrow ®) as a Potential Treatment for Androgenic Alopecia.
The objective is to investigate the safety and clinical efficacy of Autologous Platelet Rich Plasma Concentrated Spray (Keratogrow®), for hair loss. Autologous -PRP spray, prepared from a small volume of blood, was applied on the selected patients' scalps at least twice daily. Three months treatments were given for each patient. The effectiveness of the medication was measured by changes in hair regrowth after 3 months determined by physical exam and digital photography. At the end of the 3 cycles of treatment, the patients presented clinical improvement in the mean number of hairs, with a mean increase of hairs in the ta...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Efficacy of Activated 3X Platelet-Rich Plasma in the Treatment of Androgenic Alopecia.
Conclusion: PRP appears to be a cheap, effective and promising therapy for androgenic alopecia with no major adverse effects.
PMID: 28296871 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications.
Authors: Ramdasi S, Tiwari SK
Abstract
Hair loss can have major psychological impact on affected population belonging to varied ethnic background. Hair is a mini organ in itself and serves many distinguishing functions ranging from maintaining body temperature to promoting social interactions. Major cause of hair loss is androgenic alopecia. Hair follicles possess receptor for androgen. However, DHT (Dihydrotestosterone) in excess results into shrinkage of hair follicle affecting hair growth adversely.
The present review is focused on etiology of hair loss, traditional treatment approach and their ...
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
Combined Ex Vivo Organ Perfusion and Mesenchymal Stem Cells Transplantation.
Conclusion: The combined EVOP-MSCs is a therapeutic technique that should be soon applied in the practice of solid organ transplants. However, certain remarks should be considered on the pre-clinical levels before taking the studies further into the clinical levels. Although the present report will focus on the lung transplant, the ideas and the remarks are also to be considered for all other solid organ transplants, such as heart, liver and kidney.
PMID: 28296873 [PubMed - in process] (Source: Journal of Stem Cells)
Source: Journal of Stem Cells - March 18, 2017 Category: Stem Cells Tags: J Stem Cells Source Type: research
