Journal of Pharmacology and Pharmacotherapeutics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Stevens-Johnson syndrome caused by Cefepime: Erratum
Journal of Pharmacology and Pharmacotherapeutics 2015 6(3):193-193 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Source Type: research

Naloxegol: First oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation
This article gives an overview of OIC, its current management and more specifically the development and approval of naloxegol, including pharmacokinetics, details of various clinical trials, adverse effects and its current status for the management of OIC. (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Tejus AnantharamuSushil SharmaAjay Kumar GuptaNavdeep DahiyaDick B Singh BrashierAshok Kumar Sharma Source Type: research

International conference on harmonization of technical requirements for registration of pharmaceuticals for human use
Jatinder SinghJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):185-187 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Jatinder Singh Source Type: research

New drugs: New hope in the treatment of MRSA
Podila Karuna Sree, Yadala Venkata RaoJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):184-184 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Podila Karuna SreeYadala Venkata Rao Source Type: research

Authors' reply
Jayanthi Mathaiyan, Tanvi Jain, Biswajit Dubashi, K Satyanarayana Reddy, Gitanjali BatmanabaneJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):182-183 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Jayanthi MathaiyanTanvi JainBiswajit DubashiK Satyanarayana ReddyGitanjali Batmanabane Source Type: research

Prescription errors in cancer chemotherapy: Omissions supersede potentially harmful errors
Subodh KumarJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):182-182 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Subodh Kumar Source Type: research

Life-threatening bradyarrhythmia with oral phenytoin overdose
We report a case of a 41-year-old lady, who developed severe hypotension and sinus bradycardia, following oral consumption of 20 g of phenytoin and 500 mg of glibenclamide. She required high dose of inotropes and a temporary transvenous pacer for her hemodynamic instability. This life-threatening cardiotoxicity of phenytoin could have been due to its interaction with sulphonylurea. It is imperative to be aware of drug interactions, due to which, life-threatening cardiovascular manifestations following phenytoin toxicity can occur. (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Giridharan SrinivasanMukta WyawaharePratheesh George MathenDharanipragada K Subrahmanyam Source Type: research

Complete resistance after maximal dose of rocuronium
Annalisa Capuano, Maria Giuseppa Sullo, Concetta Rafaniello, Liberata Sportiello, Pierfrancesco Fusco, Macella De Vizia, Fausto FerraroJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):175-178Rocuronium is a non-depolarizing neuromuscular blocking agent (NDNMBA), employed in the clinic as an adjunct to general anesthesia to facilitate tracheal intubation rapid sequence, and to provide skeletal muscle relaxation during surgery. Many cases of resistance to neuromuscular blocking agents (NMBAs) have been anecdotally reported. There are specific pathologic states, such as upper motor neuron lesions, severe thermal inj...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Annalisa CapuanoMaria Giuseppa SulloConcetta RafanielloLiberata SportielloPierfrancesco FuscoMacella De ViziaFausto Ferraro Source Type: research

Acalculous pyelonephritis and cholecystitis occurring simultaneously in a diabetic patient on sitagliptin therapy
Jayaprakash Sahoo, Sadishkumar Kamalanathan, Muthupillai Vivekanandan, Rathinam Palamalai SwaminathanJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):172-174Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of anti-diabetic drugs. They control both fasting and postprandial hyperglycemia by inhibiting degradation of incretin hormones, such as, glucagon-like peptide-1(GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Sitagliptin is the first DPP-4 inhibitor to be marketed in India. In addition to its glucose lowering effect, it also suppresses immunity resulting in various infections in a diabe...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Jayaprakash SahooSadishkumar KamalanathanMuthupillai VivekanandanRathinam Palamalai Swaminathan Source Type: research

Intestinal pseudo-obstruction following oral baclofen: An unusual complication
We report a 50-year-old male with spasticity following cervical discectomy (C3-4) on oral baclofen for 6 months with intestinal pseudo-obstruction. He had undergone open suprapubic cystostomy for traumatic urethral injury, 45 days prior to the presentation and adhesive intestinal obstruction was also considered a possibility. However, there were no air fluid levels on abdominal radiographs and ultrasound abdomen was non-contributory. Withdrawal of baclofen was therapeutic in this patient. This case is being reported to highlight the rare possibility of oral baclofen induced intestinal pseudo-obstruction. (Source: Journal o...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Vilvapathy Senguttuvan KarthikeyanKuppusamy SenthilkumaranBettaiyagowder EaswaranRajamariappan Rajbhaskar Source Type: research

Nebivolol-induced gynecomastia
Erkan Köklü, Şakir Arslan, İsa Öner Yüksel, Nermin Bayar, Deniz DemirciJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):166-168Adverse drug reactions play a substantial role in the etiology of gynecomastia. Gynecomastia as an adverse drug reaction, related to some cardiovascular drugs, has been reported in literature. Nebivolol is a third generation beta-blocker, and gynecomastia as an adverse effect on the consumption of this drug has not been reported in any article yet. We herein present the case of a 42-year-old male, who developed bilateral gyneco...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Erkan KöklüŞakir Arslanİsa Öner YükselNermin BayarDeniz Demirci Source Type: research

Exercise-induced anaphylaxis and antileukotriene montelukast
We report a rare case of exercise-induced anaphylaxis (EIA), occurring exclusively with exercise, without any other associated trigger, detected in the prodromal phase, and prevented from additional anaphylaxis episodes by treatment with cetirizine and 10 mg daily of antileukotriene montelukast to date. EIA is a syndrome in which patients experience a spectrum of the symptoms of anaphylaxis ranging from mild cutaneous signs to severe systemic manifestations such as hypotension, syncope, and even death after increased physical activity. Many people have triggers, such as, a variety of foods, various medications, alcohol, co...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Sapna GajbhiyeRajendra Prasad AgrawalShubham AtalVikalp TiwariPradeep Phadnis Source Type: research

Double trouble: Cyclosporine-induced thrombocytosis in a patient with methotrexate toxicity: Are they related?
Cherukuri Tejaswi, Saritha Mohanan, Rangaraj Murugaiyan, Kaliaperumal KarthikeyanJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):160-162Psoriasis is a common, chronic, disfiguring, inflammatory, and proliferative condition of the skin. It manifests with varying degrees of severity and can be treated with various immune modulators. This is a case report of a 57-year-old male patient of psoriasis on long-term oral methotrexate, who developed methotrexate toxicity when given an injection of methotrexate for unstable psoriasis. After recovery, the patient was started on cyclosporine 100 mg twice a day. After a week,...
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Cherukuri TejaswiSaritha MohananRangaraj MurugaiyanKaliaperumal Karthikeyan Source Type: research

Therapeutic drug monitoring of modified release once daily tacrolimus in de novo renal transplant with conversion to a twice daily generic in the stable period
Binu Susan Mathew, Ratna Prabha, Gopal Basu, Pradeep Rajkumar, Veerasamy Tamilarasi, Denise Helen FlemingJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):156-159 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Binu Susan MathewRatna PrabhaGopal BasuPradeep RajkumarVeerasamy TamilarasiDenise Helen Fleming Source Type: research

Identification and characterization of primate P-glycoprotein
Mesfin YimamJournal of Pharmacology and Pharmacotherapeutics 2015 6(3):154-156 (Source: Journal of Pharmacology and Pharmacotherapeutics)
Source: Journal of Pharmacology and Pharmacotherapeutics - August 4, 2015 Category: Drugs & Pharmacology Authors: Mesfin Yimam Source Type: research