Journal of Pharmacological and Toxicological Methods This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

External passive heat-generating devises and body temperature support in small animals
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Lewis B. Kinter, David K. Johnson (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Inclusion of telemetry cardiovascular parameters in small molecule repeat-dose toxicity studies, a potential refinement in animal use
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Dale W. Stevens, Lisa P. Wong, Leah Schutt, Tom Gelzleichter (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

The role of standard for exchange of nonclinical data (SEND) in safety pharmacology
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Michael K. Pugsley (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

3D-Cell device with aligned and multilayered myocardial tissue derived from iPS-cells for predictive drug safety applications
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Kosuke Hori, Noriyuki Kawahara, Koshi Kinoshita, Norie Tooi, Yuka Yamamoto, Mie Yabuuchi, Junki Uda, Norio Nakatsuji, Kazuhiro Aiba (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Assessment of hypertrophic cardiomyopathy using human induced pluripotent stem cell-derived cardiomyocytes reveals abnormal excitation contraction coupling
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Natsuyo Aoyama, Jing Liu, Souameng Lor, T.K. Feaster, Simon Hilcove, Eugenia Jones (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Bernard Fermini, Denise D. Sullivan, Jerome Chal, Eli J. Fine, Shawn T. Coyne, Alexia King, Jessica Johnson, Alexander Ulan Hernandez, Chinye F. Obata, Kevin P. Coyne (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Peter Linder, Matthias Beckler, Leo Doerr, Sonja Stoelzle-Feix, Niels Fertig, Alexander Jung, Manfred Staat, Matthias Gossmann (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Comprehensive in vitro cardiac safety assessment using human stem cell technology (CSAHi–The second stage) –Ca2+ transient platform
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Kiyoshi Takasuna, Yayoi Honda, Mahoko Asayama, Hideaki Mitsui, Chifumi Nagano, Natsumi Kato, Sunao Hisada (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Characterization of contractile properties of hIPSC-CMs cultured with or without fibroblast and chronic electrical stimulation
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Minxue Huang, Hong Shi, Paul Levesque (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Assessment of human induced pluripotent stem-cell derived cardiomyocytes for evaluating drug induced arrhythmias with multi-electrode array
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Said El-Haou, Robert W. Kirby, Louise Webdale, Marc Rogers (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

MEA analysis using human iPS cell-derived dopaminergic neurons as a model to assess central nervous system effects of pharmaceutical compounds
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Takuya Kondo, Junko Chikamoto, Hiroaki Oka, Fumio Morita, Shinji Okazaki (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Detecting drug-induced long QT and arrhythmic risks with 28 CIPA compounds using a Ca2+ transient assay in human induced pluripotent stem cell-derived cardiomyocytes: A consortium from 3 sites
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Hua Rong Lu, Haoyu Zeng, Ralf Kettenhofen, Liang Guo, Ivan Kopljar, Ammel, Tekle Fetene, Jennifer Pierson, David J. Gallacher (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Live-cell biosensors reveal novel insight into neurotoxic and cardiotoxic compound mediated cellular stress response
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Kevin Harlen, Thom Hughes, Chris Fleming, Greg Luerman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Farbod Famili, Tsang Wai Lam, Pieter van Loenen, Peter Nacken, Maaike Bras, Saman Honarnejad, Yang Jiang, Viola Borgdroff, Heribert Bohlen, Arie Reijerkerk, Helma Rutjes, Stefan Braam, Greg Luerman (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Tessa de Korte, Berend van Meer, Ana Krotenberg Garcia, Leon Tertoolen, Peter J. Clements, Anthony Bahinski, Eric I. Rossman, Xiaoping Xu, Samantha Turner, Chris Denning, Marijn Vlaming, Stefan Braam, Christine Mummery (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research