Mutations in the genes for keratin ‐4 and keratin‐13 in Swedish patients with white sponge nevus
ConclusionWe describe a novel heterozygous missense mutation in the keratin‐4 gene of a Swedish family with white sponge nevus. Our results support the notion that mutations in keratin‐4 and keratin‐13 are the underlying cause of white sponge nevus. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - November 1, 2017 Category: Pathology Authors: Maria Westin, Elham Rekabdar, Lena Blomstrand, Per Klintberg, Mats Jontell, Jairo Robledo ‐Sierra Tags: ORIGINAL ARTICLE Source Type: research

The role of human papillomavirus in p16 ‐positive oral cancers
ConclusionWe have shown that the presence of transcriptionally active HPV rarely occurs in OSCC and that p16 is not an appropriate surrogate marker for HPV in OSCC cases. We propose that non‐viral mechanisms are responsible for the majority of IHC p16 overexpression in OSCC. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 30, 2017 Category: Pathology Authors: Simone Belobrov, Alyssa M. Cornall, Richard J. Young, Kendrick Koo, Christopher Angel, David Wiesenfeld, Danny Rischin, Suzanne M. Garland, Michael McCullough Tags: ORIGINAL ARTICLE Source Type: research

Porphyromonas gingivalis lipopolysaccharide induces over production of CC chemokine ligand 2 via toll ‐like receptor‐4 in oral lichen planus
ConclusionIncreased TLR‐4 expression contributes to the upregulated expression of CCL2 in the epithelium of OLP lesions, which suggests that oral bacteria participate in the pathogenesis of OLP via the TLR‐4 pathway.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 23, 2017 Category: Pathology Authors: Qi Zeng, Xi Yang, Xiaobing Chen, Juan Xia, Bin Cheng, Xiaoan Tao Tags: Original Article Source Type: research

Tumor ‐derived exosomes enhance invasion and metastasis of salivary adenoid cystic carcinoma cells
ConclusionThe results suggested that SACC cells‐derived exosomes were loaded with individual components that could enhance invasiveness and induce microenvironment changes, thus promoting SACC aggression.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 23, 2017 Category: Pathology Authors: Jin Hou, Fangyuan Wang, Xiaohao Liu, Mengyang Song, Xuemin Yin Tags: Original Article Source Type: research

Cell proliferation is associated with intensity of tumor budding in oral squamous cell carcinoma
ConclusionCell proliferation is positively associated with intensity of tumor budding in OSCC. Moreover, in tumors showing high‐intensity tumor budding, the budding area is the location of higher cell proliferation. These findings reinforce the hypothesis that tumor budding is associated with the biological behavior of OSCC.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 20, 2017 Category: Pathology Authors: Helv écio Marangon Junior, Priscila Laiza Rubim Leão, Victória Vasconcellos Moreira Melo, Ângela Braga Caixeta, Paulo Eduardo Alencar Souza, Maria Cássia Ferreira Aguiar, Martinho Campolina Rebello Horta Tags: Original Article Source Type: research

Functional analysis of ESM1 by siRNA knockdown in primary and metastatic head and neck cancer cells
ConclusionThese findings suggest that ESM1 has roles on proliferation and migration of head and neck cancer cells.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 11, 2017 Category: Pathology Authors: Onur Bender, Mehmet Gunduz, Sadik Cigdem, Omer Faruk Hatipoglu, Muradiye Acar, Mesut Kaya, Reidar Grenman, Esra Gunduz, Kadriye Serife Ugur Tags: Original Article Source Type: research

Macrophages and prognosis of oral squamous cell carcinoma: A systematic review
Journal of Oral Pathology&Medicine, EarlyView. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 6, 2017 Category: Pathology Source Type: research

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Journal of Oral Pathology&Medicine, Ahead of Print. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 6, 2017 Category: Pathology Source Type: research

Should we be rethinking follow ‐up for oral cancer patients?
(Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 4, 2017 Category: Pathology Authors: Marieke T. Brands, Matthias A. W. Merkx, Sandra M. E. Geurts, Peter A. Brennan Tags: EDITORIAL Source Type: research

Ductal cells of minor salivary glands in Sj ögren's syndrome patients express LINE‐1 ORF2p and APOBEC3B
ConclusionsL1 ORF2p and APOBEC3B are expressed in the ductal epithelial cells of minor salivary glands that are among the key targets in Sjögren's syndrome. L1 ORF2p expression may promote the L1 ability to act as an intrinsic antigen in Sjögren's syndrome. The potential future use of L1 ORF2‐reverse transcriptase inhibitors in autoimmunity supports further investigation of L1 epigenetic regulation by APOBEC3 enzymes.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Eleni ‐Marina Kalogirou, Evangelia P. Piperi, Konstantinos I. Tosios, Evangelos Tsiambas, Galinos Fanourakis, Alexandra Sklavounou Tags: Original Article Source Type: research

Clinicopathologic significance of ROCK2 expression in oral squamous cell carcinomas
ConclusionsThe findings suggest that high ROCK2 expression in OSCC is associated with advanced disease and follows the increase in CAF density, which may be important for tumor progression.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Mauricio Rocha Dourado, Carine Ervolino Oliveira, Iris Sawazaki ‐Calone, Elias Sundquist, Ricardo D. Coletta, Tuula Salo Tags: Original Article Source Type: research

Mutations in the genes for keratin ‐4 and ‐13 in Swedish patients with white sponge nevus
ConclusionWe describe a novel heterozygous missense mutation in the keratin‐4 gene of a Swedish family with white sponge nevus. Our results support the notion that mutations in keratin‐4 and ‐13 are the underlying cause of white sponge nevus.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Maria Westin, Elham Rekabdar, Lena Blomstrand, Per Klintberg, Mats Jontell, Jairo Robledo ‐Sierra Tags: Original Article Source Type: research

MicroRNA profiling reveals dysregulated microRNAs and their target gene regulatory networks in cemento ‐ossifying fibroma
ConclusionmiRNA dysregulation occurs in COF and EZH2, XIAP, MET and TGFBR1 are potential targets for functional analysis validation.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Tha ís dos Santos Fontes Pereira, João Artur Ricieri Brito, André Luiz Sena Guimarães, Carolina Cavaliéri Gomes, Júlio Cesar Tanos de Lacerda, Wagner Henriques de Castro, Roney Santos Coimbra, Marina Gonçalves Diniz, Ricardo Santiago Gomez Tags: Original Article Source Type: research

The role of human papillomavirus in p16 positive oral cancers
ConclusionWe have shown that the presence of transcriptionally active HPV rarely occurs in OSCC and that p16 is not an appropriate surrogate marker for HPV in OSCC cases. We propose that non‐viral mechanisms are responsible for the majority of IHC p16 overexpression in OSCC.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Simone Belobrov, Alyssa M. Cornall, Richard J. Young, Kendrick Koo, Christopher Angel, David Wiesenfeld, Danny Rischin, Suzanne M. Garland, Michael McCullough Tags: Original Article Source Type: research

Odontogenic myxoma: a 63 ‐year retrospective multicenter study of 85 cases in a Brazil population and a review of 999 cases from literature
ConclusionsThe features of OM samples have strong similarity to that reported in studies from other continents. It is possible to infer that geographic variation does not help to explain some differences observed in the clinical features of OM.This article is protected by copyright. All rights reserved. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Ana Carolina Uchoa Vasconcelos, Felipe Martins Silveira, Ana Paula Neutzling Gomes, Sandra Beatriz Chaves Tarquinio, Ana Paula Veras Sobral, Jos é Alcides Almeida de Arruda, Leorik Pereira da Silva, Marcia Maria Fonseca da Silveira, Larissa Ferreira Barb Tags: Original Article Source Type: research