Anesthetic Management of Rhinoorbitocerebral Mucormycosis; Focus on Challenges
This study aimed to evaluate the anesthetic management of patients undergoing surgical resection for rhino-orbito-cerebral mucormycosis (ROC).The study evaluated 12 patients that underwent surgical resection for ROC mucormycosis under general anesthesia. Demographic characteristics, hemodynamic parameters, invasive monitoring methods, surgical procedures, hospital records, and mortality rates were reviewed for each patient.The patients had a median age of 58 (range, 5-86) years. Two patients had an American Society of Anesthesiologists (ASA) score of II while the remaining 10 patients had a score of III. Eleven (91.7%) pat...
Source: Journal of Medical Mycology - July 27, 2019 Category: Biology Source Type: research
Saksenaea vasiformis infections: a review of the published literature
Publication date: Available online 25 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Konstantinos Samaras, Anthi-Marina Markantonatou, Dimitrios Karapiperis, Polidoros Digonis, Nikolaos Kartalis, Nikolaos Kostogloudis, Timoleon-Achilleas VyzantiadisAbstractSaksenaea vasiformis is an emerging human pathogen, belonging to the order Mucorales of the subphylum Mucormycotina, most often associated with rhino-cerebral, cutaneous and subcutaneous infections following trauma. A review of the published literature was attempted on the occasion of a cutaneous leg infection with favorable outcome in a young immunocompetent ...
Source: Journal of Medical Mycology - July 26, 2019 Category: Biology Source Type: research
The epidemiology of Candida species in the Middle East and North Africa
Publication date: Available online 26 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Sara Ghazi, Rayane Rafei, Marwan Osman, Dima El Safadi, Hassan Mallat, Nicolas Papon, Fouad Dabboussi, Jean-Philippe Bouchara, Monzer HamzeAbstractIn recent decades, the epidemiology of invasive candidiasis (IC) has progressively changed worldwide. This notably includes emergence of several Candida species. Although some surveillance programs provided global trends in IC epidemiology, data from countries from the Middle East and North Africa (MENA) remain scarce. In this manuscript, we reviewed the existing available data on the...
Source: Journal of Medical Mycology - July 26, 2019 Category: Biology Source Type: research
Mode of action and anti-Candida activity of Artemisia annua mediated-synthesized silver nanoparticles
Publication date: Available online 26 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Nafeesa Khatoon, Yamini Sharma, Meryam Sardar, Nikhat ManzoorAbstractCandida albicans is a polymorphic opportunistic commensal that causes both superficial and systemic fungal infections especially in immunocompromised patients. Biologically synthesized silver nanoparticles (AgNPs) have emerged as potential antifungal agents. The present work evaluates the antifungal activity of Artemisia annua synthesized AgNPs against three Candida species (C. albicans ATCC 90028, C. tropicalis ATCC 750 and C. glabrata ATCC 90030). The in vitr...
Source: Journal of Medical Mycology - July 26, 2019 Category: Biology Source Type: research
A systematic review and meta-analysis on the epidemiology, casual agents and demographic characteristics of onychomycosis in Iran
Publication date: Available online 5 July 2019Source: Journal de Mycologie MédicaleAuthor(s): Z. Rafat, S.J. Hashemi, A.-A. Saboor-Yaraghi, B. Pouragha, A. Taheriniya, A. Moosavi, B. Roohi, R. Arjmand, A. Moradi, R. Daie-Ghazvini, S. BasiriAbstractOnychomycosis or fungal nail infection is one of the most common fungal infections. Nearly 50% of all nail disorders are caused by fungi. This systematic review and meta-analysis was conducted to determine the prevalence of onychomycosis across Iran. We searched English and Persian databases for studies reporting the epidemiologic features of onychomycosis in Iranian people from...
Source: Journal of Medical Mycology - July 7, 2019 Category: Biology Source Type: research
Inhibition of the growth of human dermatophytic pathogens by selected australian and asian plants traditionally used to treat fungal infections
ConclusionWhilst multiple extracts inhibited fungal growth, the methanolic S. australe and S. luehmannii leaf extracts and the S. luehmannii fruit extracts showed particularly potent activity against each of these dermatophytes, indicating that they are promising leads for the development of anti-dermatophytic therapeutics. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 25, 2019 Category: Biology Source Type: research
Interactions between oral commensal Candida and oral bacterial communities in immunocompromised and healthy children
This study focused on the first step of cooperation between microorganisms isolated from the same oral flora either of leukemic or healthy children. C. albicans isolated from 8/20 children were cultured to display their noninvasive blastosporic yeast form and mixed with their dominant bacteria to study the capacity of planktonic aggregation and the early state of biofilm formation. None of the dominant bacteria opposed the presence of yeast, on the contrary, an interesting cooperation was observed. This behavior is apparently different from that observed when mixing the type strains. In fact, three mutated C. albicans st...
Source: Journal of Medical Mycology - June 22, 2019 Category: Biology Source Type: research
In vitro expression of vital virulent genes of clinical and environmental isolates of Cryptococcus neoformans/gattii in endothelial cells of human blood-brain barrier
ConclusionThe C. gattii (VGI) isolates showed significantly lower invasion and survival than C. neoformans (VNI, and VNII) irrespective of their sources. Clinical isolates exhibited higher expression for the majority of the virulent genes until 12 hours of infection, probably due to their better adaptation in the host system and enhanced pathogenicity than the environmental counterparts. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 18, 2019 Category: Biology Source Type: research
Epidemiology and antifungal susceptibility testing of non-albicans Candida species colonizing mucosae of HIV-infected patients in Yaoundé (Cameroon)
Publication date: Available online 14 June 2019Source: Journal de Mycologie MédicaleAuthor(s): T.K. Ngouana, R.M.K. Toghueo, I.F. Kenfack, L. Lachaud, A.K. Nana, L. Tadjou, C. Kouanfack, F.F. Boyom, S. BertoutAbstractNon-albicans Candida (NAC) species have emerged as potent pathogenic yeasts among HIV-infected patients. Authors evaluated the epidemiology and antifungal susceptibility testing of non-albicans Candida species colonizing Yaoundé (capital of the Republic of Cameroon, Central Africa) HIV-infected patients. The mucosal specimens were collected and submitted to the mycological diagnosis. Yeast isolates were iden...
Source: Journal of Medical Mycology - June 15, 2019 Category: Biology Source Type: research
Disseminated fungal infection due to Saprochaete clavata in a kidney transplant recipient
Publication date: Available online 13 June 2019Source: Journal de Mycologie MédicaleAuthor(s): P. Pavone, A. Oliva, G. Raponi, F. Pugliese, S. Martelli, P. Celli, F. Sacco, V. Vullo, C.M. Mastroianni, G. RussoAbstractSaprochaete clavata and Saprochaete capitata are closely related fungal species (family Dipodascaceae, order Saccharomycetales) that are rarely involved in the etiology of systemic infections in humans. In recent years, these yeasts are emerging as cause of life-threatening infections in patients with severe neutropenia and haematological malignancies. Infections by these fungi have been reported mostly from ...
Source: Journal of Medical Mycology - June 13, 2019 Category: Biology Source Type: research
Editorial Board
Publication date: June 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 2Author(s): (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 7, 2019 Category: Biology Source Type: research
Candida auris, an emerging and disturbing yeast
Publication date: June 2019Source: Journal de Mycologie Médicale, Volume 29, Issue 2Author(s): A.T. Coste, C. Imbert, C. Hennequin (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 7, 2019 Category: Biology Source Type: research
Cladosporium sphaerospermum causing brain abscess, a saprophyte turning pathogen: Case and review of published reports
Publication date: Available online 2 May 2019Source: Journal de Mycologie MédicaleAuthor(s): N. Batra, H. Kaur, S. Mohindra, S. Singh, A.S. Shamanth, S.M. RudramurthyAbstractEmergence of saprophytic fungi thriving in dead plant material and soil as opportunistic human pathogens is of great concern. Cladosporium species are environmental saprophytes reported to cause various superficial and invasive fungal infections worldwide. C. sphaerospermum, a predominantly indoor fungus has been reported from cases of meningitis, subcutaneous and pulmonary fungal infections in the past. Herein we report the first case of cerebral ab...
Source: Journal of Medical Mycology - May 4, 2019 Category: Biology Source Type: research
Detection of Pneumocystis jirovecii by quantitative real-time PCR in oral rinses from Pneumocystis pneumonia asymptomatic human immunodeficiency virus patients
In conclusion, although rare, a positive oral rinse P. jirovecii result may reflect colonisation, in particular in patients with HIV. This needs to be kept in mind when using oral rinses and qRT-PCR in the diagnosis of P. jirovecii infection. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - May 1, 2019 Category: Biology Source Type: research
Methods for identification of Candida auris, the yeast of global public health concern: A review
Publication date: Available online 26 April 2019Source: Journal de Mycologie MédicaleAuthor(s): S. Mahmoudi, S. Agha Kuchak Afshari, S. Aghaei Gharehbolagh, H. Mirhendi, K. MakimuraAbstractCandida auris has recently emerged as a fungus able to cause severe infections, especially bloodstream infections with high mortality rates. This multi-drug-resistant yeast has the capacity of persistence on environmental surfaces, and has been reported to cause hospital-acquired infections. The development of faster and inexpensive tools for identification is critical to controlling, preventing and establishing early diagnosis of this ...
Source: Journal of Medical Mycology - April 26, 2019 Category: Biology Source Type: research
