Response to J-Y. Maillard: Are amine-only-containing products sporicidal?
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): S. Gemein, B. Meyer, J. Gebel, C. Roques, K. Steinhauer, On behalf of CEN TC 216, WG1 (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Reducing the risk of iatrogenic Creutzfeldt–Jakob disease by improving the cleaning of neurosurgical instruments
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): A. Smith, S. Winter, D. Lappin, A. Sherriff, I. McIvor, P. Philp, N. Suttner, S. Holmes, A. StewartSummaryBackgroundIn all, there have been 178 variant Creutzfeldt–Jakob disease (vCJD) patients diagnosed in the UK, with an estimated maximum 1:2000 carriage rate based on archived appendix and tonsil tissue, implying that infection may be rare but carriage relatively frequent. Previous workers have identified that maintenance of surgical instruments in a humid atmosphere after use and prior to cleaning assists cleaning e...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Responding to Mycobacterium chimaera heater-cooler unit contamination: international and national intersectoral collaboration coordinated in the state of Queensland, Australia
ConclusionsRapid international collaboration optimized the Queensland Health response to potential M. chimaera exposure during cardiac surgery. State-wide collaboration ensured a transparent, consistent approach to contacting patients and informing the public of the potential risk. A framework for ongoing risk management, clinical awareness and laboratory diagnosis was established. No further cases of M. chimaera infection have been identified in Queensland. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Transfer of dry surface biofilm in the healthcare environment: the role of healthcare workers' hands as vehicles
ConclusionDSB bacteria are transferred by hands from one fomite to multiple fomites, suggesting that DSB may serve as a persistent environmental source of pathogens. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Airborne Aspergillus fumigatus spore concentration during demolition of a building on a hospital site, and patient risk determination for invasive aspergillosis including azole resistance
ConclusionsThe results suggest that with implemented preventive measures, there is no increased risk for IA, including azole resistance, in immunocompromised patients during outdoor demolition work. Further prospective studies are needed to confirm these findings. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Minimizing microbial contamination risk simultaneously from multiple hospital washbasins by automated cleaning and disinfection of U-bends with electrochemically activated solutions
ConclusionSimultaneous automated treatment of multiple hospital washbasin U-bends with ECA consistently minimizes microbial contamination and thus the associated risk of infection. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Characterizations of handwashing sink activities in a single hospital medical intensive care unit
ConclusionSeveral non-hand hygiene activities took place regularly in ICU handwashing sinks; these may provide a mechanism for nosocomial transmission and promotion of bacterial growth in the drain. Redesigning hospital workflow and sink usage may be necessary as it becomes apparent that sink drains may be a reservoir for transmission of multidrug-resistant bacteria. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Is there an association between airborne and surface microbes in the critical care environment?
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): J. Smith, C.E. Adams, M.F. King, C.J. Noakes, C. Robertson, S.J. DancerSummaryBackgroundThere are few data and no accepted standards for air quality in the intensive care unit (ICU). Any relationship between airborne pathogens and hospital-acquired infection (HAI) risk in the ICU remains unknown.AimFirst, to correlate environmental contamination of air and surfaces in the ICU; second, to examine any association between environmental contamination and ICU-acquired staphylococcal infection.MethodsPatients, air, and surfaces we...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Reusable endoscopic water bottles: is daily renewal really necessary?
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): D. Jouck, K. Magerman, L. Bruckers, L. Waumans, A. Forier, M. Blommen, D. WalgraeveSummaryMost guidelines recommend replacing endoscopic water bottles at least daily with newly sterilized or high-level disinfected water bottles. All these recommendations, however, are mainly based on expert opinions and outbreak reports. We tested the water quality from water bottles used in a gastrointestinal endoscopy unit where water bottles were used up to five days. The results show that the reuse of water bottles for more than one day ...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

State of the art on Mycobacterium chimaera research: a bibliometric analysis
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): Y. Ortiz-Martínez, C. Galindo-Regino, M.R. González-Hurtado, J.J. Vanegas-Pastrana, F. Valdes-Villegas (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Response to Schmidt et al.: Antimicrobial surfaces – huge potential, significant uncertainty
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): M.P. Muller, C. MacDougall, M. Lim, S. Callery, W. Ciccotelli, M. Cividino, S. Hota, G. Garber, J. Johnstone, K. Katz, V. Nankoosingh (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Implementation of tailored interventions in a statewide programme to reduce central line-associated bloodstream infections
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): D.B. Assis, G. Madalosso, M.C. Padoveze, R.D. Lobo, M.S. Oliveira, Í. Boszczowski, J.M. Singer, A.S. LevinSummaryBackgroundThere have been few studies exploring implementation strategies to central line-associated bloodstream infections (CLABSIs) in low- or middle-income countries.AimTo implement tailored interventions to reduce CLABSI rates in adult intensive care units.MethodsThe implementation strategy of the State Health Department was performed in São Paulo State, Brazil, over two cycles. Cycle 1 (56 ...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Trends in device utilization ratios in intensive care units over 10-year period in South Korea: device utilization ratio as a new aspect of surveillance
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): E.J. Kim, Y.G. Kwak, S.H. Park, S.R. Kim, M.J. Shin, H.M. Yoo, S.H. Han, D.W. Kim, Y.H. Choi, J.H. Yoo, H.Y. Kim, Y.S. Kim, Y.H. Kim, T.H. Kim, H.B. Kim, K.-W. Moon, Y. Uh, B.W. Eun, M.S. Lee, S.-O. LeeSummaryBackgroundDevice-associated infection (DAI) is an important issue related to patient safety. It is important to reduce unnecessary device utilization in order to decrease DAI rates.AimTo investigate the time trend of device utilization ratios (DURs) of voluntarily participating hospitals, collected over a 10-year period...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

The optimal ethanol lock therapy regimen for treatment of biofilm-associated catheter infections: an in-vitro study
Publication date: November 2018Source: Journal of Hospital Infection, Volume 100, Issue 3Author(s): B. Alonso, M.J. Pérez-Granda, A. Rodríguez-Huerta, C. Rodríguez, E. Bouza, M. GuembeSummaryBackgroundEthanol-based lock therapy (LT) solutions are used as an alternative to antibiotics for the conservative management of catheter-related bloodstream infection. However, no clear consensus on regimen or dose has been reached.AimTo find the ethanol-based lock solution containing a sufficiently low concentration of ethanol for reduction of the metabolic activity of bacterial and fungal biofilms.MethodsUsing a...
Source: Journal of Hospital Infection - October 24, 2018 Category: Infectious Diseases Source Type: research

Value of a hospital-wide point prevalence survey of carbapenemase-producing Enterobacterales – low-level prevalence confirmed
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): J. Cafferkey, M. Skally, C. Finn, S. Donlon, M. Fitzpatrick, K. Burns, K. O'Connell, F. Fitzpatrick, E. Smyth, H. Humphreys (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Evaluation of microbiological screening in a neonatal intensive care unit to optimize empiric antibiotic use
Publication date: Available online 4 October 2018Source: Journal of Hospital InfectionAuthor(s): I. Schmeh, A. Kidszun, A. Welk, T. Schwanz, B. Jansen, E. Mildenberger (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Exposure to infected/colonized roommates and prior room occupants increases the risks of healthcare-associated infections with the same organism
ConclusionsThis meta-analysis showed exposure to infected/colonized roommates and prior room occupants significantly increased the risk of HAI with the same organism. Health authorities and hospitals should attach higher importance to the fact that current standards or practices for disinfection and isolation are often not sufficient to block transmission of pathogens in the healthcare settings, which may warrant enhanced terminal and intermittent disinfection and strict isolation for reducing HAIs. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Effectiveness of Behavioural Interventions to Reduce Urinary Tract Infections and E. coli Bacteraemia for Older Adults Across all Care Settings: A Systematic Review
ConclusionsThe heterogeneity of studies means one effective intervention cannot be recommended. We suggest feedback should be considered because it facilitated reductions in UTI when used alone or in multifaceted interventions including education, audit or catheter removal protocols. Multi-faceted education is likely to be effective. Catheter removal protocols, increased staffing and patient education require further evaluation. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Whole genome sequencing of toxigenic C. difficile in asymptomatic carriers: insights into possible role in transmission
ConclusionThis small study of asymptomatic carriage has revealed a rectal asymptomatic carriage rate of 14.6% in patients nursed in ICBFs, and a high level of genetic similarity of these strains to those recovered from symptomatic patients. Consequently, we feel that asymptomatic carriers might be important for the transmission of symptomatic CDI, although we acknowledge that the study was small, and there are many other factors which govern whether C. difficile is carried asymptomatically, or causes symptoms. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Floor and environmental contamination during glove disposal
Publication date: Available online 23 October 2018Source: Journal of Hospital InfectionAuthor(s): K.M. Munoz-Gutierrez, R.A. Canales, K.A. Reynolds, M.P. VerhougstraeteSummaryBackgroundEvidence suggests that doffing and possibly disposal of used personal protective equipment (PPE) can lead to environmental contamination.AimTo ascertain the potential for site and floor contamination when medical gloves are inappropriately disposed.MethodsFifteen healthcare workers (HCWs) disposed of gloves inoculated with bacteriophage and a chemical dye into a wastebasket, located 1.22 m away. Following each trial, designated sample areas ...
Source: Journal of Hospital Infection - October 23, 2018 Category: Infectious Diseases Source Type: research

Opportunities lost may be the greatest cost of CPE outbreaks
Publication date: Available online 22 October 2018Source: Journal of Hospital InfectionAuthor(s): C.P. Dunne, B.L. Slevin, P. Treacy, N.H. O’Connell (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 22, 2018 Category: Infectious Diseases Source Type: research

Reply to Abbas et al. “Infection prevention: Is copper the new gold?”
Publication date: Available online 20 September 2018Source: Journal of Hospital InfectionAuthor(s): J. Butler (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 20, 2018 Category: Infectious Diseases Source Type: research

Vagino-rectal colonization and maternal–neonatal transmission of Enterobacteriaceae producing extended-spectrum β-lactamases or carbapenemases: a cross-sectional study
This study sought to determine the prevalence and risk factors for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) in 815 mothers and 800 newborns using a cross-sectional design; 59 women and 13 neonates were colonized by ESBL-E (prevalence (95% confidence interval): 6.7% (5.2–8.7) and 1.6 (0.7–2.5), respectively). No CPE were found. The most frequent ESBL-E were CTX-M-14 and SHV-12. Vertical transmission occurred in 14% of colonized mothers. The risk factors for colonization were, in mothers: complications in previo...
Source: Journal of Hospital Infection - October 20, 2018 Category: Infectious Diseases Source Type: research

Timing, diagnosis, and treatment of surgical site infections after colonic surgery: prospective surveillance of 1263 patients
ConclusionOrgan space infections occurred early in the postoperative course, whereas incisional infections were mostly detected post discharge over the entire 30-day observation period, emphasizing the importance of proper follow-up using a systematic, complete and independent surveillance programme. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 20, 2018 Category: Infectious Diseases Source Type: research

Challenging the six-hour recommendation for reprocessing sterilizable medical equipment
ConclusionNo association was identified between residual protein and holding time, nor between incidence of corrosion and holding time. The study thereby challenges the relevance of upholding the recommendation of a maximum wait of 6 h prior to reprocessing. The findings will potentially have an impact on the organization of reprocessing of surgical instruments in Denmark and internationally. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 17, 2018 Category: Infectious Diseases Source Type: research

Hand hygiene and infection control in limited-resource countries: Still a big challenge
Publication date: Available online 15 October 2018Source: Journal of Hospital InfectionAuthor(s): M. Mostafazadeh-Bora (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 16, 2018 Category: Infectious Diseases Source Type: research

Ex vivo and in vivo evaluation of residual chlorhexidine gluconate on skin following repetitive exposure to saline and wiping of 2% chlorhexidine gluconate/70% isopropyl alcohol preoperative skin preparations
ConclusionThe addition of a film-forming copolymer has the potential to improve the retention of CHG on skin throughout a surgical procedure compared to a water-soluble prep. This improved retention may lead to better antimicrobial activity. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 16, 2018 Category: Infectious Diseases Source Type: research

Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumonia patients: a randomized controlled crossover trial
Publication date: Available online 15 October 2018Source: Journal of Hospital InfectionAuthor(s): C.C.H. Leung, G.M. Joynt, C.D. Gomersall, W.T. Wong, A. Lee, L. Ling, P.K.S. Chan, P.C.W. Lui, P.C.Y. Tsoi, C.M. Ling, M. HuiSummaryWhereas high-flow nasal cannula use is gaining prevalence, its high gas flow raises concerns about aerosolization of infectious particles and spread of infection. This randomized controlled crossover non-inferiority trial (N = 20) evaluated the degree of environmental contamination by viable bacteria associated with the use of high-flow nasal cannula compared with conventional oxygen mask for crit...
Source: Journal of Hospital Infection - October 15, 2018 Category: Infectious Diseases Source Type: research

Whole genome sequencing reveals a prolonged and spatially spread nosocomial outbreak of Panton–Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus (USA300)
ConclusionWGS helped to reveal an outbreak that otherwise might have stayed undetected. Nonetheless, epidemiological investigation is needed to trace the nosocomial transmission. The importance of personal communication in infection control cannot be overstated. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Inform rather than ambush CPE patient contacts
Publication date: Available online 12 October 2018Source: Journal of Hospital InfectionAuthor(s): C.P. Dunne, N.H. O’Connell, B. O’Brien (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Automated detection of outbreaks of antimicrobial-resistant bacteria in Japan
Publication date: Available online 12 October 2018Source: Journal of Hospital InfectionAuthor(s): Atsuko Tsutsui, Koji Yahara, Adam Clark, Kenichi Fujimoto, Sayoko Kawakami, Hiroki Chikumi, Mitsutaka Iguchi, Tetsuya Yagi, Meghan A. Baker, Thomas O’Brien, John StellingSummaryBackgroundHospital outbreaks of antimicrobial-resistant (AMR) bacteria should be detected and controlled as early as possible.AimTo develop a framework for automatic detection of AMR outbreaks in hospitals.MethodsJapan Nosocomial Infections Surveillance (JANIS) is one of the largest national AMR surveillance systems in the world. For this study, a...
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Increased Detection Of Carbapenemase-Producing Enterobacteriaceae On Post-Clean Sampling Of Burns Units Wet Surfaces
We report the increased detection of bla-IMP-4+ CPE in environmental samples from floor drains in Burns Unit shower rooms, when collected following cleaning as compared to pre-cleaning. We propose that disruption of biofilms during cleaning may account for the increased detection of multi-resistant organisms. The results highlight the role of the wet environment as an under-recognised potential source of CPE transmission. Environmental screening focusing on pre-cleaning samples alone will likely under-estimate environmental contamination. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Bacterial colonization of bladeless electrical fans
Publication date: Available online 5 September 2018Source: Journal of Hospital InfectionAuthor(s): L. Alsaffar, L. Osborne, N.T. Bourne (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Fibrin Sheath Infections Can Be Safely and Successfully Treated with Percutaneous Vacuum-Assisted Thrombectomy
Publication date: Available online 11 October 2018Source: Journal of Hospital InfectionAuthor(s): Evan Y. Choi, Jose M. Taveras, Jacob Cynamon, Janine Adamczyk, Cynthia C. Taub (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 13, 2018 Category: Infectious Diseases Source Type: research

Carbapenem-resistant Gram-negative bloodstream infections in critically ill children: outcome and risk factors in a tertiary teaching hospital in South America
Publication date: Available online 10 October 2018Source: Journal of Hospital InfectionAuthor(s): Paula A. Alvares, Mariana V. Arnoni, Cely B. da Silva, Marco Aurélio P. Sáfadi, Marcelo J. Mimica (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 11, 2018 Category: Infectious Diseases Source Type: research

Critical points in the pathway of antibiotic prescribing in a children's hospital: the Antibiotic Mapping of Prescribing (ABMAP) study
ConclusionThere was a marked disparity between prescribers, self-reporting of prescribing behaviour and responses to clinical scenarios. It was not clear whether training alone would change behaviours. Prescribers desired a directive mechanism to support antibiotic prescribing and stewardship. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Barriers and enablers to meticillin-resistant Staphylococcus aureus admission screening in hospitals: a mixed-methods study
ConclusionTo our knowledge, this is the first study to provide original evidence of barriers and enablers to MRSA screening, applying both sociological and psychological theory. As antimicrobial resistance is a global health concern, these findings have international relevance for screening programmes. Future policy recommendations or behaviour change interventions, based on the insights presented here, could have significant impact upon improving screening compliance. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

An evaluation of microbiological screening in a neonatal ICU to optimize empiric antibiotic use
Publication date: Available online 4 October 2018Source: Journal of Hospital InfectionAuthor(s): Isabella Schmeh, André Kidszun, Alexa Welk, Thomas Schwanz, Bernd Jansen, Eva Mildenberger (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Transferring knowledge into practice: a multi-modal, multi-centre intervention for enhancing nurses' infection control competency in Bangladesh
Publication date: Available online 3 August 2018Source: Journal of Hospital InfectionAuthor(s): L. Ara, F. Bashar, M.E.H. Tamal, N.K.A. Siddiquee, S.M.N. Mowla, S.A. SarkerSummaryBackgroundNurses are considered as the key to infection prevention as they play a major role in treatment as well as taking care of patients.AimTo assess the role of a multi-modal intervention (MMI) in improving nurses' competency and adherence to standard infection control practices in Bangladesh.MethodsThe study adopted a pretest–post-test intervention approach, in three different periods (from 2012 to 2017) in five hospitals (two public, ...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Risk behaviours for organism transmission in daily care activities: a longitudinal observational case study
ConclusionInterventions aimed at reducing the risks of healthcare-associated infections need to focus on strategies that address: hand hygiene compliance; the handling of materials, equipment, work clothes and surfaces; the effects of interruptions in care activities if they are to alter healthcare personnel's infection prevention behaviour sufficiently. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Hospital bronchoscopy-related pseudo-outbreak caused by a circulating Mycobacterium abscessus subsp. massiliense
This study aimed to analyse the clonality of isolates. Mycobacterium abscessus subsp. massiliense isolated from 28 patients, water from one bronchoscope and water from four automated endoscope reprocessing machines presented high similarity by pulsed-field gel electrophoresis. This strain was not found in the water supply, and it was hypothesized that an infected patient contaminated the bronchoscope, with further false-positive cultures from subsequent patients. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Survey of screening methods, rates and policies for the detection of carbapenemase-producing Enterobacteriaceae in English hospitals
Publication date: Available online 7 August 2018Source: Journal of Hospital InfectionAuthor(s): C. Berry, K. Davies, N. Woodford, M. Wilcox, C. ChiltonSummaryMulti-drug-resistant Gram-negative bacteria are of major clinical concern. The increasing prevalence of carbapenemase-producing Enterobacteriaceae (CPE), resistant to all beta-lactams including carbapenems and able to colonize the large intestine, represents a key threat. Rapid, accurate detection of intestinal CPE colonization is critical to minimize transmission, and hence reduce costly, difficult-to-treat CPE infections. There is currently no ‘gold standard&r...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The socio-economic impact of multidrug-resistant nosocomial infections: a qualitative study
Publication date: Available online 29 August 2018Source: Journal of Hospital InfectionAuthor(s): Y. Mo, I. Low, S.K. Tambyah, P.A. TambyahSummaryThe burden of healthcare-associated infections (HCAIs) has traditionally been measured using clinical and economic outcomes. We conducted semi-structured interviews with 18 patients or their caregivers affected by HCAI caused by multidrug-resistant organisms to better understand the human impact of HCAI. Most patients had misconceptions about HCAI and antimicrobial resistance, leading to strong negative feelings towards HCAIs despite positive views of their healthcare providers. C...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Novel colour additive for bleach disinfectant wipes reduces corrosive damage on stainless steel
Publication date: Available online 24 September 2018Source: Journal of Hospital InfectionAuthor(s): Kevin Tyan, Katherine Jin, Jason KangSummaryBleach disinfectant wipes are corrosive to hospital surfaces and equipment. We measured the effect of two widely used bleach wipes, with and without Highlight® colour additive, on stainless steel to both quantify corrosion rate and determine the effect of Highlight® on reducing surface damage caused by bleach wipes. The two bleach wipes alone caused severe corrosion (>5 mpy) while the addition of Highlight® both significantly reduced corrosion rate (
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Timing, diagnosis and treatment of surgical site infections after colonic surgery – Prospective surveillance of 1263 patients
ConclusionOrgan space infections occurred early in the postoperative course, while incisional infections were mostly detected post-discharge over the entire 30-day observation period, emphasizing the importance of proper follow-up using a systematic, complete and independent surveillance program. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Antifungal Activity of Octenidine Dihydrochloride and Ultraviolet-C light against Multidrug-Resistant Candida auris
Publication date: Available online 25 September 2018Source: Journal of Hospital InfectionAuthor(s): Pretty Ponnachan, Vivek Vinod, Unnimaya Pullanhi, Parvathy Varma, Sanjeev Singh, Raja Biswas, Anil KumarAbstractOutbreaks due to multidrug-resistant Candida auris have emerged as a large threat to modern medicine. Since skin colonization and environmental contamination have been identified as a precursor for outbreaks, we evaluated the antifungal activity of ultraviolet-C light using mercury vapor lamp with a peak emission of 254±2 nm and octenidine dihydrochloride against C. auris clinical isolates. Octenidine dihydr...
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

The role of the environment in the spread of healthcare associated infections
Publication date: Available online 26 September 2018Source: Journal of Hospital InfectionAuthor(s): A.P.R. Wilson (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

A qualitative study of the factors impacting Antimicrobial Stewardship program delivery in regional and remote hospitals
ConclusionAMS program delivery in regional hospitals is influenced by factors that are not present in major-city hospitals. These findings provide a strong basis for the development of specific strategies to support regional hospitals to implement sustainable AMS programs. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Impact of test protocols and material binding on antimicrobial wipes efficacy
ConclusionsThe use of different wiping cloth materials might not impact severely on the efficacy of potent disinfectants despite the absorption of different volumes of formulation by the materials. QAC-based formulations may be more at risk when a low concentration is used. There were large differences in efficacy depending on the standard test performed, highlighting the need for more stringency in choosing the test to make a product claim on label. (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research

Why volume matters - Implications of applied volume of alcohol-based disinfectants for infection prevention
Publication date: Available online 28 September 2018Source: Journal of Hospital InfectionAuthor(s): Katrin Steinhauer, Hans-Joachim Rödger, Karin Teckemeyer, Bärbel Christiansen, Jürgen Gebel, Heike Martiny, Bernhard Meyer, Christiane Ostermeyer, Lutz Vossebein (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - October 5, 2018 Category: Infectious Diseases Source Type: research