A mechanistic and empirical review of antcins, a new class of phytosterols of formosan fungi origin
Publication date: Available online 5 October 2019Source: Journal of Food and Drug AnalysisAuthor(s): K.J. Senthil Kumar, M. Gokila Vani, Chieh-Yin Chen, Wen-Wei Hsiao, Jing Li, Zhan-xi Lin, Fang-Hua Chu, Gow-Chin Yen, Sheng-Yang WangAbstractAntcins are unique phytosterols isolated from A. cinnamomea and A. salmomea, which are the endemic fungus of Taiwan. A. cinnamomea has long been highly valued medicinal mushroom in Taiwan and traditionally used as a folk remedy for various human illness. Recent scientific explorations claimed that the pharmacological activities of A. cinnamomea and A. salmomonea are gone beyond their or...
Source: Journal of Food and Drug Analysis - October 6, 2019 Category: Food Science Source Type: research
Determination of higenamine in multi-matrix by gas chromatography-mass spectrometry combined with derivatization technology
We report the development of a gas chromatography-mass spectrometry (GC–MS) method for determination of HG in various matrix samples (biological samples, different forms of Chinese patent medicine, Chinese herbal medicine) based on acylation derivatization of HG by heptafluorobutyric anhydride. Under optimal conditions, the linearity of HG in the range of 5–200 ng mL−1 was acceptable (R2 > 0.999), and the limit of detection (LOD) and limit of quantitation (LOQ) for HG was 1.52 ng mL−1 and 5 ng mL−1, respectively. Low, medium, and high concentrations (25, 100 and 160 ng mL−1) of HG were added to plasma...
Source: Journal of Food and Drug Analysis - October 6, 2019 Category: Food Science Source Type: research
Checklist
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Editorial Board
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Instruction to Authors
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Acknowledgment of Reviewers
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Author Index
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Keyword Index
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Title Index
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Authorship & Conflicts of Interest Statement
Publication date: October 2019Source: Journal of Food and Drug Analysis, Volume 27, Issue 4Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - October 5, 2019 Category: Food Science Source Type: research
Polysaccharide-containing fraction from Artemisia argyi inhibits tumor cell-induced platelet aggregation by blocking interaction of podoplanin with C-type lectin-like receptor 2
Publication date: Available online 26 September 2019Source: Journal of Food and Drug AnalysisAuthor(s): Ching-Ping Tseng, Yu-Ling Huang, Yao-Wen Chang, Hsiang-Ruei Liao, Yu-Li Chen, Pei-Wen HsiehAbstractTumor cell-induced platelet aggregation (TCIPA) is a mechanism that involves the protection of tumor cells in the circulation and the promotion of tumor cell invasion and metastases. The C-type lectin-like receptor 2 (CLEC-2) that binds podoplanin (PDPN) is on the platelet surface and facilitates the TCIPA. Selective blockage of the PDPN-mediated platelet-tumor cell interaction is thereby a plausible strategy for inhibiting...
Source: Journal of Food and Drug Analysis - September 27, 2019 Category: Food Science Source Type: research
Estimation of nizatidine gastric nitrosatability and product toxicity via an integrated approach combining HILIC, in silico toxicology, and molecular docking
Publication date: Available online 22 August 2019Source: Journal of Food and Drug AnalysisAuthor(s): Rania El-Shaheny, Mahmoud El-Maghrabey, Mohamed Radwan, Koji YamadaAbstractThe liability of the H2-receptor antagonist nizatidine (NZ) to nitrosation in simulated gastric juice (SGJ) and under WHO-suggested conditions was investigated for the first time. For monitoring the nitrosatability of NZ, a hydrophilic interaction liquid chromatography (HILIC) method was optimized and validated according to FDA guidance. A Cosmosil HILIC® column and a mobile phase composed of acetonitrile: 0.04 M acetate buffer pH 6.0 (92:8, v/v) w...
Source: Journal of Food and Drug Analysis - August 23, 2019 Category: Food Science Source Type: research
Carboxymethyl chitosan perturbs inflammation profile and colonic microbiota balance in mice
Publication date: Available online 21 August 2019Source: Journal of Food and Drug AnalysisAuthor(s): Yuting Liu, Shuai Zong, Jinglei LiAbstractCarboxymethyl chitosan (CMC) is widely used in food and medicine as a biodegradable polymer. However, its effects on inflammation profile and colon health are not well investigated. In the present study, CMC was given to mice to evaluate its possible effects on body weight, blood glucose level, inflammation factors, intestinal permeability and colon microbiota. Results show that blood glucose level of CMC treated mice was relatively higher than control ones. Glucose tolerance test r...
Source: Journal of Food and Drug Analysis - August 22, 2019 Category: Food Science Source Type: research
Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells
In conclusion, the results demonstrated that the molecular mechanisms of quercetin in regulating apoptosis and autophagy-related pathways and increasing GEM chemosensitivity in pancreatic cancer cells involved inhibition of RAGE expression.Graphical abstractThis diagram illustrated that quercetin treatment effectively attenuated RAGE expression to facilitate autophagy, apoptosis, and GEM chemosensitivity in MIA Paca-2 and MIA Paca-2 GEMR cells. (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - August 22, 2019 Category: Food Science Source Type: research
Impact of dietary ingredients on the interpretation of various fecal parameters in rats fed inulin
Publication date: Available online 16 July 2019Source: Journal of Food and Drug AnalysisAuthor(s): Hui-Ju Chen, Fan-Jhen Dai, Chih-Ren Chang, Yie-Qie Lau, Boon-Swee Chew, Chi-Fai ChauAbstractIn the present study, the influences of diets (i.e. chow and AIN-93 diets) on the interpretation of various fecal parameters including viable microbiota, moisture, weight, and short-chain fatty acids in rats fed different amounts of inulin (0.5–2 g/kg). Eight groups of rats (n = 8/group) were fed, for 4 weeks, chow or AIN-93 diets with or without inulin supplementation. Fecal samples were analyzed for different fecal parameters. A...
Source: Journal of Food and Drug Analysis - July 18, 2019 Category: Food Science Source Type: research
