Authorship & Conflicts of Interest Statement
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
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Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Instructions to Authors
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Recent progress in natural dietary non-phenolic bioactives on cancers metastasis
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Gow-Chin Yen, Chiung-Man Tsai, Chi-Cheng Lu, Chia-Jui WengAbstractFrom several decades ago to now, cancer continues to be the leading cause of death worldwide, and metastasis is the major cause of cancer-related deaths. For health benefits, there is a great desire to use non-chemical therapy such as nutraceutical supplementation to prevent pathology development. Over 10,000 different natural bioactives or phytochemicals have been known that possessing potential preventive or supplementary effects for various diseases includin...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Pyrrole-protein adducts – A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Jiang Ma, Qingsu Xia, Peter P. Fu, Ge LinAbstractPyrrolizidine alkaloids (PAs) are phytotoxins identified in over 6000 plant species worldwide. Approximately 600 toxic PAs and PA N-oxides have been identified in about 3% flowering plants. PAs can cause toxicities in different organs particularly in the liver. The metabolic activation of PAs is catalyzed by hepatic cytochrome P450 and generates reactive pyrrolic metabolites that bind to cellular proteins to form pyrrole-protein adducts leading to PA-induced hepatotoxicity. The...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Lactic acid bacteria-fermented product of green tea and Houttuynia cordata leaves exerts anti-adipogenic and anti-obesity effects
This study aims to develop a novel anti-obesity fermentation product by combining H. cordata leaf tea with green tea, using Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) for fermentation due to the advantages of bioconverting the polyphenolic compounds. The regulation of adipogenesis factors and the anti-obesity effect of the NTU 101-fermented tea were evaluated in an in vitro 3T3-L1 pre-adipocyte model and an in vivo obese rat model, respectively. The results show that the NTU 101-fermented tea, which contained higher EGCG, EGC, and chlorogenic acid levels than unfermented tea, was able to inhibit the lipog...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
4-O-Caffeoylquinic acid as an antioxidant marker for mulberry leaves rich in phenolic compounds
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Jerome G. Ganzon, Lih-Geeng Chen, Ching-Chiung WangAbstractMulberry (Morus alba L.) leaves are widely used as herbal tea to prevent heat stroke. Potential chemical markers of the antioxidant properties and its correlation with harvesting times and leaf location were explored in this study. A 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay guided isolation of mulberry leaves extract provided five phenolic compounds: 5-O-caffeoylquinic acid (1), 4-O-caffeoylquinic acid (2), gastrodin (3), isoquercetin (4) and ruti...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Concentrations of perfluoroalkyl substances in foods and the dietary exposure among Taiwan general population and pregnant women
This study quantified five perfluorocarboxylic acids (PFCAs) and two perfluorosulfonic acids in cereals, meats, seafood, eggs, pork liver, and milk in Taiwan using ultra-performance liquid chromatography-tandem mass spectrometry and evaluated the dietary exposure of the general population and pregnant women using per capita consumption and a questionnaire, respectively. Perfluorooctanoic acid (PFOA) and PFCAs of 10–12 carbons were found in almost all of the samples in considerable concentrations in rice and pork liver, reaching as high as 283 ng/g (PFOA in pork liver); the levels are two to three orders of magnitude hig...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein, FIP-fve, extract from Flammulina velutipes
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Ching-Hsin Tung, Chih-Chieh Lin, Huei-Ju Wang, Sung-Fang Chen, Fuu Sheu, Ting-Jang LuAbstractFungal immunomodulatory protein (FIP-fve) is a potential functional food ingredient. However, undesirable component flammutoxin (FTX) would occur in the extracted fraction of FIP-fve. In this paper, an application of heating processing instead of the intensive separation process was employed in fractionation of FIP-fve, meanwhile, exclusion of FTX was reached. Contents of FIP-fve and FTX were monitored by HPLC-UV-ESI-MS. Both FIP-fve ...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Sarah M. Richart, Yi-Lin Li, Yoshiyuki Mizushina, Yuan-Yen Chang, Tse-Yu Chung, Guan-Heng Chen, Jason Tze-Cheng Tzen, Kak-Shan Shia, Wei-Li HsuAbstractCurcumin (Cur), a polyphenolic compound extracted from spice and common food colourant turmeric, contains versatile bio-activities. Monoacetylcurcumin (MAC), a structural analogue of Cur, differs from Cur by acetyl modification, but retains enone groups. Comparative analysis revealed MAC effectively inhibited influenza virus infection (IAV) to a similar extent as, if not superi...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Mulberry leaf extract inhibit hepatocellular carcinoma cell proliferation via depressing IL-6 and TNF-α derived from adipocyte
In this study, adipocytes from 3T3-L1 cells were induced and stained with Oil Red O, which revealed marked intracellular lipid accumulation. Adding 15% conditioned medium (CM) from adipogenic -differentiated 3T3-L1 cells, which contained adipocyte-derived factors, to a culture medium of HepG2 cells was discovered to promote cell proliferation by a factor of up to 1.3 compared with the control. Mulberry leaf extract (MLE), with major components including chlorogenic acid and neochlorogenic acid, was revealed to inhibit CM-promoted HepG2 cell proliferation. The inhibitory effect of MLE on the proliferation of the signal netw...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Elemental profile and oxygen isotope ratio (δ18O) for verifying the geographical origin of Chinese wines
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Shuangxi Fan, Qiding Zhong, Hongbo Gao, Daobing Wang, Guohui Li, Zhanbin HuangAbstractThe elemental profile and oxygen isotope ratio (δ18O) of 188 wine samples collected from the Changji, Mile, and Changli regions in China were analyzed by inductively coupled plasma mass spectrometry (ICP-MS), inductively coupled plasma optical emission spectroscopy (ICP-OES) and isotope ratio mass spectrometry (IRMS), respectively. By combining the data of δ18O and the concentration data of 52 elements, the analysis of variance (ANOVA) tec...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Combination of on-line desalting and HPLC-UV-ESI-MS for simultaneous detection and identification of FIP-fve and flammutoxin in Flammulina velutipes
In this study, a highly efficient desalting method is provided using molecular weight cut-off centrifugal filtration and on-line desalting. Sample preparation followed by an on-line desalting HPLC-UV-ESI-MS system was employed for simultaneous desalting and detection and identification of FIP-fve and FTX. Results indicated that using trifluoroacetic acid as a modifier on a C18 reversed-phase column renders effective separation. ESI-MS revealed that the apparent molecular masses of FIP-fve and FTX were 12,749.1 Da and 21,912.5 Da, respectively. Eleven milligrams of FIP-fve was obtained from 100 g of fresh fruiting bodies...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Improvement of nutritional components and in vitro antioxidative properties of soy-powder yogurts using Lactobacillus plantarum
Publication date: July 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 3Author(s): Jin Hwan Lee, Chung Eun Hwang, Eun Ju Cho, Yeong Hun Song, Su Cheol Kim, Kye Man ChoAbstractThis research was the first to demonstrate changes in nutritional compositions (isoflavone and CLA) from the 50% methanol extracts of soy-powder milk (SPM) and soy-powder yogurt (SPY) through fermentation using Lactobacillus plantarum S48 and P1201 strains. The radical scavenging activities and protective effects against oxidative stress in LLC-PK1 cells were also investigated. The average physicochemical characteristics including acid...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
Resveratrol protects muscle cells against palmitate-induced cellular senescence and insulin resistance through ameliorating autophagic flux
In conclusion, impairment of autophagic flux is crucial for palmitate-induced cellular senescence and insulin resistance in muscle cells. Restoring autophagic flux by resveratrol could be a promising approach to prevent cellular senescence and ameliorate insulin resistance in muscle.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research
