In vitro and in vivo assessment of delivery of hydrophobic molecules and plasmid DNAs with PEO–PPO–PEO polymeric micelles on cornea
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Feichin Hsiao, Po-Yang Huang, Takao Aoyagi, Shwu-Fen Chang, Jiahorng LiawAbstractThe stability and bio-distribution of genes or drug complexes with poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO–PPO–PEO, Pluronic F-68) polymeric micelles (PM) are essential for an effective nanosized PM delivery system. We used Förster resonance energy transfer (FRET) pairs with PM and measured the FRET ratio to assess the stability of PM in vitro and in vivo on the cornea. The FRET ratio reached a plateau at 0.8 ...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Ultra-sensitive electrochemical sensing of acetaminophen and codeine in biological fluids using CuO/CuFe2O4 nanoparticles as a novel electrocatalyst
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Foroozan Hasanpour, Masoumeh Taei, Somayeh TahmasebiAbstractCopper ferrite−copper oxide (CuO-CuFe2O4) nanoparticles as a semiconductor composite with p–n junction were synthesized by co-precipitation reaction. Then, a novel CuO-CuFe2O4 carbon paste modified electrode was fabricated which displays an effectual electrocatalytic response to the oxidation of acetaminophen (AC) and codeine (CO). A linear range of 0.01–1.5 μmol L−1 and 0.06–10.0 μmol L−1 with the detection limits of 0.007 μmol L−1 and 0.01 ...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Triple-component nanocomposite films prepared using a casting method: Its potential in drug delivery
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Sadia Gilani, Sadullah Mir, Momina Masood, Abida Kalsoom Khan, Rehana Rashid, Saira Azhar, Akhtar Rasul, Muhammad Nadeem Ashraf, Muhammad Khurram Waqas, Ghulam MurtazaAbstractThe purpose of this study was to fabricate a triple-component nanocomposite system consisting of chitosan, polyethylene glycol (PEG), and drug for assessing the application of chitosan–PEG nanocomposites in drug delivery and also to assess the effect of different molecular weights of PEG on nanocomposite characteristics. The casting/solvent evaporatio...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR–CaMKII–ERK/CREB signalling on consumption of aspartame in rat model
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Ashok Iyaswamy, Ananth Kumar Kammella, Citarasu Thavasimuthu, W.har W.upar, W.har Dapkupar, Sambantham Shanmugam, Ravindran Rajan, Sheeladevi RathinasamyAbstractMany controversial reports are available on the use of aspartame as it releases methanol as one of its metabolite during metabolism. The present study proposes to investigate whether long term (90 days) aspartame (40 mg/kg b.wt) administration could induce oxidative stress and alter the memory in Wistar strain male albino rats. To mimic the human methanol metabolism...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Exploration of Wedelia chinensis leaf-assisted silver nanoparticles for antioxidant, antibacterial and in vitro cytotoxic applications
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Merina Paul Das, Jeyanthi Rebecca Livingstone, Pandiyarasan Veluswamy, Jayabrata DasAbstractGreen synthetic route of silver nanoparticles (AgNPs) has already been proved to be an advantageous over other physico-chemical approaches due to its simplicity, cost effectiveness, ecofriendly and nontoxicity. In this finding, aqueous Wedelia chinensis leaf extract (WLE) mediated synthesis of AgNPs was approached. Surface plasmon resonance (SPR) band at 408 nm preliminary indicated the formation of AgNPs, while TEM and XRD character...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Instructions to Authors
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Checklist
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Authorship & Conflicts of Interest Statement
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Volatile sulfur compounds in tropical fruits
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Robert J. Cannon, Chi-Tang HoAbstractGlobal production and demand for tropical fruits continues to grow each year as consumers are enticed by the exotic flavors and potential health benefits that these fruits possess. Volatile sulfur compounds (VSCs) are often responsible for the juicy, fresh aroma of tropical fruits. This poses a challenge for analytical chemists to identify these compounds as most often VSCs are found at low concentrations in most tropical fruits. The aim of this review is to discuss the extraction methods...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Standards and labeling of milk fat and spread products in different countries
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Chia-Lin Lee, Huei-Lin Liao, Wan-Chen Lee, Chao-Kai Hsu, Fwu-Chyn Hsueh, Jyh-Quan Pan, Chih-Hsuan Chu, Chieh-Ting Wei, Ming-Ju ChenAbstractIn the present paper, we provide comprehensive information related to labeling claims and standards of identity of milk fat and spread products. By reviewing the standards and regulations for dairy and non-dairy fat products, Codex Alimentarius and several other countries have clearly specified these products and set the requirements for use of the product name to prevent misleading or co...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Regulatory analysis on the medical use of ephedrine-related products in Taiwan
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Wan-Nan Yu, Li-Hsuan Wang, Hui-Wen ChengAbstractTo prevent ephedrine-related products from being misused to produce amphetamine and/or its analogs, there's a need for more effective and achievable regulatory mechanisms for the health, police, investigational, prosecution and judiciary authorities in Taiwan. This review was conducted to evaluate the international and Taiwan's regulatory policies and management of medical ephedrine-related products through the corresponding information collected from international and Taiwan g...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and their glucose-lowering activities
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Cara Welch, Jing Zhen, Emmanuel Bassène, Ilya Raskin, James Edward Simon, Qingli WuAbstractHerbal tea kinkéliba prepared from the leaves of Combretum micranthum has been widely consumed in West African countries for its flavor, nutritional and medicinal properties. Under bio-guided screening, the kinkéliba leaves were chemically investigated using various chromatographic and spectrometric methods that led to the identification of thirteen different flavonoid compounds. Further biological tests illustrated that the identif...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Characterization of key aroma-active compounds in lychee (Litchi chinensis Sonn.)
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Shi Feng, Mingyang Huang, Jonathan Henry Crane, Yu WangAbstractVolatile compounds in ‘Sweetheart’ lychee were examined using gas chromatography-olfactometry/mass spectrometry (GC-O/MS). Solvent assisted flavor evaporation (SAFE) technique was used to identify the aroma-active compounds in lychee. Further characterization of the most important odorants in ‘Sweetheart’ lychee was achieved using aroma extract dilution analysis (AEDA). Thirty-one key aroma-active odorants were identified in the flavor dilution (FD) facto...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

A simple and robust quantitative analysis of retinol and retinyl palmitate using a liquid chromatographic isocratic method
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Satoshi Yokota, Shigeru OshioAbstractVitamin A is a vital nutritional substances that regulates biological activities including development, but is also associated with disease onset. The extent of vitamin A intake influences the retinoid content in the liver, the most important organ for the storage of vitamin A. Measurement of endogenous retinoid in biological samples is important to understand retinoid homeostasis. Here we present a reliable, highly sensitive, and robust method for the quantification of retinol and retiny...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research

Effects of electrode gap and electric current on chlorine generation of electrolyzed deep ocean water
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Guoo-Shyng Wang Hsu, Shun-Yao HsuAbstractElectrolyzed water is a sustainable disinfectant, which can comply with food safety regulations and is environmental friendly. A two-factor central composite design was adopted for studying the effects of electrode gap and electric current on chlorine generation efficiency of electrolyzed deep ocean water. Deep ocean water was electrolyzed in a glass electrolyzing cell equipped with platinum-plated titanium anode and cathode in a constant-current operation mode. Results showed that cu...
Source: Journal of Food and Drug Analysis - July 11, 2018 Category: Food Science Source Type: research