TC ‐325 versus the conventional combined technique for endoscopic treatment of peptic ulcers with high‐risk bleeding stigmata: A randomized pilot study
CONCLUSIONSOur pilot study showed that TC‐325 has a tendency towards a higher rebleeding rate than CCT, when treating actively bleeding ulcers. Larger trials are necessary for definitive results. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - July 27, 2017 Category: Gastroenterology Authors: Boon Eu Andrew Kwek, Tiing Leong Ang, Peng Lan Jeannie Ong, Yi Lyn Jessica Tan, Shih Wen Daphne Ang, Ngai Moh Law, Prem Harichander Thurairajah, Kwong Ming Fock Tags: Original Article Source Type: research
Single disease entity for both chromosomal instable subtype gastric adenocarcinoma and esophageal adenocarcinoma
Gastric cardiac carcinoma (GCC) was and is considered as a part of esophageal adenocarcinoma (EAC) and staged with the rules for EAC. This may change. Recent comprehensive integrated genomic investigations on gastric and esophageal carcinomas discovered similar chromosomal instability profiles in these two groups of carcinomas with a gradual increasing gradient from the lowest percentage in the distal gastric antrum to a high level in the proximal gastric cardia, and to the peak of almost 100% in EAC. Therefore, most GCCs and EAC share similar chromosomal instable features of gastric carcinoma and should be grouped as a si...
Source: Journal of Digestive Diseases - July 27, 2017 Category: Gastroenterology Authors: Qin Huang Tags: Short Review Source Type: research
Issue Information ‐ TOC
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - July 27, 2017 Category: Gastroenterology Tags: Issue Information ‐ TOC Source Type: research
Clinical Outcomes of Patients with Resectable Pancreatic Acinar Cell Carcinoma
ConclusionsCompared with ductal adenocarcinoma, resectable pancreatic ACC has a favorable prognosis after surgery. Considering distant metastasis is the most common relapse pattern, further studies are necessary to define the role of adjuvant chemotherapy for improving survival outcomes. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - July 3, 2017 Category: Gastroenterology Authors: Seyoung Seo, Changhoon Yoo, Kyu ‐Pyo Kim, Baek‐Yeol Ryoo, Heung‐Moon Chang, Seung‐Mo Hong, Jae Hoon Lee, Ki Byung Song, Dae Wook Hwang, Ki‐Hun Kim, Shin Hwang, Song Cheol Kim Tags: Original article Source Type: research
Adherence to infliximab therapy in inflammatory bowel disease patients in a real ‐life setting
CONCLUSIONSThe overall non‐adherence rate for infliximab use was 54.3%. Professional constraints and intentional non‐adherence were the leading causes of non‐adherence. Perineal disease and active CD were negatively related to adherence. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - July 1, 2017 Category: Gastroenterology Authors: Laura Martelli, Anthony Lopez, Sophie Strobel, Silvio Danese, Xavier Roblin, C édric Baumann, Laurent Peyrin‐Biroulet Tags: Original article Source Type: research
Issue Information ‐ PI
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 29, 2017 Category: Gastroenterology Tags: Issue Information ‐ PI Source Type: research
Combination of growth pattern and tumor regression identifies a high ‐risk group in neoadjuvant treated rectal cancer patients
CONCLUSIONSLoss of E‐cadherin protein expression in the pretreatment biopsy of rectal cancer is associated with fewer metastases and improved survival. Furthermore, the growth pattern in the post‐RCT resection specimen has a prognostic value for survival. A combination of growth pattern and tumor regression score (the RegPat score) showed the highest discriminatory power to identify high‐risk patients. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 29, 2017 Category: Gastroenterology Authors: Jonas Jessberger, Katharina Erlenbach ‐Wünsch, Rebecca Posselt, Marlen Haderlein, Abbas Agaimy, Rainer Fietkau, Arndt Hartmann, Luitpold Distel Tags: Original Article Source Type: research
Diagnostic performance of confocal laser endomicroscopy for atrophy and gastric intestinal metaplasia: A meta ‐analysis
CONCLUSIONCLE is of great value and may be considered an alternative modality for the early diagnosis of GA and GIM. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 29, 2017 Category: Gastroenterology Authors: Tao Bai, Lei Zhang, Stuti Sharma, Yu Dong Jiang, Jing Xia, Huan Wang, Wei Qian, Jun Song, Xiao Hua Hou Tags: Meta Analysis Source Type: research
POEM for special patient cohorts: A review
Peroral endoscopic myotomy (POEM) is a natural orifice, translumenal endoscopic surgical procedure that achieves endoscopic myotomy by conducting a submucosal tunnel as an operating space. It is conventionally performed in achalasia. Recently, several centers worldwide have reported the feasibility of this procedure not only in early achalasia but also in other particular patient cohorts. Possible indications for POEM include previously failed Heller myotomy, pneumatic balloon dilatation or POEM, sigmoid achalasia, pediatric patients, spastic esophagus disorders, Zenker’s diverticulum and gastroparesis. However, its appl...
Source: Journal of Digestive Diseases - June 29, 2017 Category: Gastroenterology Authors: Dan Mu, Yue Yue Li, Ming Ming Zhang, Yan Zhang, Zhen Li, Yan Qing Li Tags: Review Article Source Type: research
Issue Information ‐ TOC
(Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 29, 2017 Category: Gastroenterology Tags: Issue Information ‐ TOC Source Type: research
Comparison of 10 days levofloxacin bismuth based quadruple therapy and levofloxacin based triple therapy for Helicobacter pylori therapy
ConclusionsWe found that addiction of bismuth subcitrate to levofloxacin‐based triple therapy was not more effective, but no more side effects were noted. These two eradication therapy were equally safe, and patients seems to have the same tolerant. Levofloxacin‐resistant rate may be a more important role when choosing second‐line therapy. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 23, 2017 Category: Gastroenterology Authors: Tzung ‐Shiun Wu, Ping‐I Hsu, Chao‐Hung Kuo, Huang‐Ming Hu, I‐Chen Wu, Sophie S.W. Wang, Yen‐Hsu Chen, Deng‐Chyang Wu, Wei‐Wen Su, Fu‐Chen Kuo Tags: Original article Source Type: research
Long ‐term risk of infection in patients with Crohn's disease on anti‐TNF treatment: A prospective single center cohort study in China
ConclusionsLong‐term use of infliximab in patients with Crohn's disease has a high risk of infectious complications. Failure of mucosal healing and concomitant systemic corticosteroids treatment are independent risk factors of infectious events during IFX maintenance therapy. Copyright © 2017 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 23, 2017 Category: Gastroenterology Authors: Yue Li, Hui Jun Shu, Hong Lu, Hong Yang, Ji Li, Bei Tan, Jiaming Qian Tags: Original article Source Type: research
Clinical Characteristics and Outcome of Liver Transplantation for Alagille Syndrome in Children
ConclusionLiver transplantation is an effective treatment for Alagille syndrome with end‐stage liver disease, which is better for the patients’ growth. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 23, 2017 Category: Gastroenterology Authors: Tao Zhou, Jianjun Zhang, Yi Luo, Yuan Liu, Sy Zhuang, Feng Xue, Longzhi Han, Qiang Xia Tags: Case report Source Type: research
Evaluation of three Techniques for detection of IL28B SNP: a prognostic tool for HCV treatment outcome
ConclusionHence, it could be suggested that for routine medical practice screening of IL28B rs12979860 could be done by PCR‐Restriction fragment Length polymorphism that is the efficient and reliable as well as cost effective method. Copyright © 2017 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 13, 2017 Category: Gastroenterology Authors: Bushra Khubaib, Muhammad Idrees, Zareen Fatima, Madiha Akram, Samia Afzal, Iram Amin, Muhammad Shahid, Muhammad Wasim Tags: Original article Source Type: research
Endoscopic evaluation of iron deficiency without anemia: does it have the same benefit as in patients with anemia?
ConclusionsPrevalence of gastrointestinal lesions in patients without anemia was similar to that of patients with anemia but malignancy was eight times less frequent. Systematic endoscopic evaluation in patients with ID is therefore questionable. Copyright © 2017 John Wiley & Sons, Ltd. (Source: Journal of Digestive Diseases)
Source: Journal of Digestive Diseases - June 13, 2017 Category: Gastroenterology Authors: Ana Garc ía García de Paredes, Carlos Teruel Sánchez‐Vegazo, Nerea Hernanz Ruiz, Carlos Ferre Aracil, Enrique Rodríguez de Santiago, Lara Aguilera Castro, María Sierra Morales, Agustín Albillos Tags: Original article Source Type: research
