Correlation of CA19-9 and P57 (KiP2) Expression with Tumor Grade and Invasive Front in Oral Squamous Cell Carcinoma
Conclusion: Within the limitations of this study, it may be concluded that expression of CA19-9 and P57 cannot be used as determinants of tumor grade. Higher expression of CA19-9 in invasive front of SCC can be representative of local invasion and higher activity of tumor cells in the margins. (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 24, 2018 Category: Dentistry Source Type: research

Tooth Discoloration Induced by Imidazolium Based Silver Nanoparticles as an Intracanal Irrigant
Conclusion:Within the limitation of this study, silver nano particle material could not be suggested as an intra-canal irrigant regarding its unfavourable tooth discoloration. (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 24, 2018 Category: Dentistry Source Type: research

Determinants of Oral Health Behavior among Preschool Children: Application of the Theory of Planned Behavior
Conclusion: Based on the current finding, TBP is the important predictor of children ’s oral health behavior. Effective promotion interventions could be designed based on this predictor to help improving the children’s oral hygiene behavior.  (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 24, 2018 Category: Dentistry Source Type: research

Orofacial Pathological Lesions in Children and Adolescents: A 25-year survey in Iran
Conclusion: The most frequent lesions were odontogenic cysts and reactive lesions. The prevalence of lesions was not changed dramatically during the 25 year. The frequency of oral lesions in Isfahan province (in Iran) is different from other regions in the world and even, to some extent, different from other regions in Iran, which is in agreement with the hypothesis of geographical distribution of these lesions. (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 24, 2018 Category: Dentistry Source Type: research

Quercetin Decreases Th17 Production by Down-Regulation of MAPK- TLR4 Signaling Pathway on T Cells in Dental Pulpitis
Conclusion:Our results indicated that the levels of IL-17, IL-33, and IL-6 in supernatants from patients ’ cultured T cells were increased after stimulation with HMGB-1 following employing quercetin. It also could inhibit MAPK signaling pathway, which subsequently could decrease Th17 production and IL-17. Quercetin could decrease pro-inflammatory cytokines and IL-17 production. (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 24, 2018 Category: Dentistry Source Type: research

Evaluation of Cyclin D1 Expression in Aggressive and Nonaggressive Central Giant Cell Granuloma of the Jaws
Conclusion: Probably overexpression of cyclin D1 implicates in the pathogenesis of the central giant cell granulomas but it seems that this protein could not be used as a marker for identifying the clinical behavior of these lesions. (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - November 23, 2018 Category: Dentistry Source Type: research

Gummy Smile Correction Using Botulinum Toxin With Respective Gingival Surgery
The pursuit of esthetic excellence has become a major goal in the dental treatment and orthodontic treatment. The beauty of the smile is not only constituted by the shape, position, and size of the teeth, but also based on the characteristics of the gingival tissue and conformation of the lips, which should be as harmonious as teeth. Gummy smile is one of the complaints of the patients, since such a situation can influence self-esteem and social relationships. The development of new more conservative techniques may provide a better therapeutic option than surgical procedures, such as the application of botulinum toxin, in ...
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Endodontic Management of Calcified Oehler ’s Type IIIb Dens Invaginatus in Permanent Maxillary Lateral Incisor Using Cone Beam Computed Tomography
Dens Invaginatus is a developmental disturbance resulting from abnormal morpho differentiation. It is characterized by an invagination of the enamel and dentin, creating a lumen inside the affected tooth, which may extend as deep as the apical foramen. In the present scenario, calcified Oehler ’s type IIIb dens invaginatus in left maxillary lateral incisor in 23-year-old male patient was seen. As the two-dimensional imaging lacks accuracy in such complicated cases, cone beam computed tomography was used to assess the calcification three dimensionally. Endodontic treatment was performed in two visits, using thermoplastize...
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Prevalence of Anaerobic Bacteria (P.gingivalis) as Major Microbial Agent in the Incidence Periodontal Diseases by Meta-analysis
Conclusion: This study indicates thatP. gingivalis is highly present in subjects with periodontal diseases and it also appears in periodontally healthy people, although to a lesser extent. Thus, the presence of P. gingivalis increases the chance of periodontal disease and it can be considered as a main potential risk factor.Key Words  Porphyromonas gingivalis; Periodontal diseases; Chronic periodontitis; Aggressive periodontitis; Gingivitis;  (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Effective Factors on Oral Health Behaviors of 12-year-old Children in Cities and Villages of Iran: a Path Analysis
Conclusion: Path analysis identified some direct and indirect factors influencing the children ’s oral health-related behaviors. Factors included in this model could only justify a part of oral health behaviors. Thus, other educational models should be considered based on the psychology or social learning theories.Key Words  Behavior; Oral Health; Children;  (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Activation Toll-Like Receptor7 (TLR7) Responsiveness Associated with Mitogen- Activated Protein Kinase (MAPK) Activation in HIOEC Cell Line of Oral Squamous Cell Carcinoma
Conclusion: TLR7 is functionally over-expressed in HIOEC cell line of oral squamous cell carcinoma and development of resistance to cisplatin in human oral squamous cell carcinoma might occur through the mechanism involving activation of TLR7 and its dependent signaling pathway.  Key Words  Toll-Like Receptor 7; Mitogen-Activated Protein Kinase; Squamous Cell Carcinoma; (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Comparing Vitamin D Serum Levels in Patients with Oral Lichen Planus and Healthy Subjects
Conclusion:The difference between the level of vitamin D in the serum of patients suffering from oral lichen planus and healthy individuals was not significant.Key Words  Lichen Planus; Oral; Vitamin D; Serum;  (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

The Effect of Sintering Program on the Compressive Strength of Zirconia Copings
Conclusion:Within the limitations of thisin vitro study, it can be concluded that compressive strength of the zirconia copings is affected by the sintering time. High compressive strength of zirconia copings can be obtained by shortening the sintering time. Key Words  Compressive strength; Zirconia; Sintering;  (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

The Effect of Methylphenidate on Cervical Vertebral Maturation and Dental Age in Patients with Attention Deficit Hyperactivity Disorder
Conclusion:After age and sex adjustment, the dental and skeletal age of ADHD patients with or without Methylphenidate treatment do no manifest a significant delay compared with the controls.Statement of the Problem:It is postulated that attention deficit/hyperactivity disorder (ADHD) with or without medication has an inhibitory effect on the children ’s growth and development.Purpose: This study aimed to assess the dental age and cervical vertebral maturation (CVM) stage in ADHD patients with or without medication.Materials and Method: This cross-sectional study evaluated the pretreatment panoramic and lateral cephalogra...
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research

Postoperative Pain Management after Impacted Third Molar Surgery with Preoperative Oral Lamotrigine, a Randomized, Double-blind, Placebo-Controlled Trial
Conclusion: Accordingly, pre-emptive administration of lamotrigine was not effective in diminishing the postoperative acute pain of impacted third molar extraction.Key Words  Lamotrigine; Third Molar; Pain Management;    (Source: Journal of Dentistry, Shiraz University of Medical Sciences)
Source: Journal of Dentistry, Shiraz University of Medical Sciences - August 25, 2018 Category: Dentistry Source Type: research