Ageing Effects on 3-Dimensional Femoral Neck Cross-Sectional Asymmetry: Implications for Age-Related Bone Fragility in Falling
This paper explores the effects of aging on femoral neck (FN) anatomy in a study of women aged 20 –90 years in relation to implications for FN fracture propensity in buckling. Five hundred and four participants were scanned by Quantitative Computed Tomography and analyzed using Quantitative Computed Tomography Pro BIT (Mindways). FN cross-section was split through geometric center into superio r and inferior sectors. Bone mass, structural measurements, and bone mineral density were analyzed. Buckling ratio was calculated as ratio of buckling radius to cortical thickness. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 8, 2018 Category: Radiology Authors: B.C.C. Khoo, K. Brown, J.R. Lewis, E. Perilli, R.L. Prince Tags: Original Article Source Type: research
Peripheral Quantitative Computed Tomography: Review of Evidence and Recommendations for Image Acquisition, Analysis, and Reporting, Among Individuals With Neurological Impairment
In 2015, the International Society for Clinical Densitometry (ISCD) position statement regarding peripheral quantitative computed tomography (pQCT) did not recommend routine use of pQCT, in clinical settings until consistency in image acquisition and analysis protocols are reached, normative studies conducted, and treatment thresholds identified. To date, the lack of consensus-derived recommendations regarding pQCT implementation remains a barrier to implementation of pQCT technology.Thus, based on description of available evidence and literature synthesis, this review recommends the most appropriate pQCT acquisition and a...
Source: Journal of Clinical Densitometry - September 6, 2018 Category: Radiology Authors: T. Cervinka, L. Giangregorio, H. Sievanen, A.M. Cheung, B.C. Craven Tags: Review Article Source Type: research
Normative Data for Lean Mass and Fat Mass in Healthy Predominantly Breast-Fed Term Infants From 1 Month to 1 Year of Age
This study aimed to create a normative reference dataset for lean (LM) and fat (FM) mass and accretion rates in healthy infants. Methods: Healthy term-born infants (35 boys; 35 girls) were studied at ≤ 1, 3, 6, 9, and 12 mo of age for growth and compared to World Health Organization standards. LM (g) and FM (g) were measured using DXA (APEX version 13.3:3, Hologic 4500A) in infant whole-body mode. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - September 6, 2018 Category: Radiology Authors: Olusola F. Sotunde, Sina Gallo, Catherine A. Vanstone, Hope A. Weiler Tags: Original Article Source Type: research
Effect of Chemotherapy on Dual-Energy X-ray Absorptiometry (DXA) Body Composition Precision Error in Head and Neck Cancer Patients
Background: Precision error in dual-energy X-ray absorptiometry (DXA) is defined as difference in results due to instrumental and technical factors given no biologic change. The aim of this study is to compare precision error in DXA body composition scans in head and neck cancer patients before and 2 months after chemotherapy. Methodology: A total of 34 male head and neck cancer patients with normal body mass index (BMI) were prospectively enrolled and all patients received 2 consecutive DXA scans both before and after 2 months of chemotherapy for a total of 4 scans. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 30, 2018 Category: Radiology Authors: Ho-Chuen Chang, Yu-Ching Lin, Shu-Hang Ng, Yun-Chung Cheung, Cheng-Hsu Wang, Fang-Ping Chen, Hui-Ping Chang, Chen-Ming Sung, Chih-Ming Fan, Kun-Yun Yeh, Jim S. Wu Source Type: research
Atypical Femoral Fracture Associated With Overuse of Bisphosphonate Evaluated by High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT): A Case Report
Atypical femoral fracture (AFF) is defined as an atraumatic fracture on the subtrochanteric region or femoral shaft (1, 2). A population-based study in Canada reported the incidence of AFF to be 7.0 (ranging from 4.7 to 9.3) cases per 100,000 person-years (3). AFF is a rare side effect of the long-term use of bisphosphonates (4), which may attribute to severe suppression of bone turnover (5). The relative risk of AFF with bisphosphonate use was 47.3% (6). The average duration of bisphosphonate use in causing AFF is 5 yr, ranging from 3 mo to 16 yr (7). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 29, 2018 Category: Radiology Authors: Lijia Cui, Yuping Xu, Qiming Xu, Yan Jiang, Ou Wang, Mei Li, Xiaoping Xing, Weibo Xia Tags: Case Report Source Type: research
Effects of Traction on Interpretation of Lumbar Bone Mineral Density in Patients with Duchenne Muscular Dystrophy: A New Measurement Method and Diagnostic Criteria Based on Comparison of Dual-Energy X-Ray Absorptiometry and Quantitative Computed Tomography
This study aimed to compare the performance of dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) in evaluating bone mineral density (BMD) of patients with Duchenne muscular dystrophy and scoliosis. Methodology: Twenty-nine participants (mean age 19.72 ± 6.13 years) underwent whole spine radiography, DXA before and after traction, and QCT alone without traction. Scoliosis and vertebral rotation angles obtained before and after traction were compared, and BMD values from DXA were compared to those obtained via QCT. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 22, 2018 Category: Radiology Authors: Je-Sang Lee, Keunyoung Kim, Yun Kyung Jeon, Jinmi Kim, Da Hwi Jung, Sang Hun Kim, Myung Jun Shin, Yong Beom Shin Source Type: research
Karate Training Improves Skeletal Status Assessed by Quantitative Ultrasound in Girls and Premenopausal Women
The aim of the study was to assess the influence of regular karate training on the skeletal status evaluated by quantitative ultrasound (QUS) in females. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 18, 2018 Category: Radiology Authors: P. Adamczyk, W. Pluskiewicz Tags: Original Article Source Type: research
Periprosthetic Bone Mineral Density Changes After Implantation of a Curved Bone Preserving Hip Stem Compared to a Standard Length Straight Stem: 5-Yr Results of a Prospective, Randomized DEXA-Analysis
The objective of this prospective, randomized study was to evaluate differences in periprosthetic bone mineral density changes in the proximal femur after implantation of a cementless bone preserving stem (Fitmore) compared to a cementless straight stem (CLS Spotorno). Methodology: Periprosthetic bone mineral density was measured in 140 patients (aged 33 –74 yr) before surgery, 7 d, 3, 12, and 60 mo postoperatively, using dual energy X-ray absorptiometry. The 1-yr results have already been published. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 17, 2018 Category: Radiology Authors: Julian S. Meyer, Tobias Freitag, Heiko Reichel, Ralf Bieger Tags: Original Article Source Type: research
Vertebral Bone Density Measurements by DXA are Influenced by Hepatic Iron Overload in Patients with Hemoglobinopathies
Interference from metal hardware (piercings; buttons on clothing; and ingested material, e.g. barium) is well documented in bone health assessments by dual-energy X-ray absorptiometry (DXA). It is unknown if iron in hepatic tissue of highly iron-loaded patients could be mistakenly assessed by DXA as bone, and if this would lead to increased areal bone mineral density (aBMD) lumbar spine Z-scores derived by DXA. Our hypothesis is that iron in the liver of heavily loaded patients will artificially raise aBMD in the spine, and thereby lead to an error in the DXA scan. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 16, 2018 Category: Radiology Authors: Haven M. Allard, Lisa Calvelli, Marcela G. Weyhmiller, Ginny Gildengorin, Ellen B. Fung Tags: Original Article Source Type: research
Bone Mineral Density Around the Knee Joint: Correlation With Central Bone Mineral Density and Associated Factors
Introduction: The aims of this study were to (1) assess the bone mineral density (BMD) around the knee joint, (2) determine the correlation between central and knee BMDs, and (3) investigate the factors associated with BMD around the knee joint in patients with knee osteoarthritis (OA). Methodology: This cross-sectional study included 122 patients who underwent total knee arthroplasty. Central and knee dual-energy X-ray absorptiometry was performed preoperatively. BMD at 6 regions of interest (ROIs) around the knee joint were measured, and their correlations with central BMD were determined using Spearman's correlation ana...
Source: Journal of Clinical Densitometry - August 15, 2018 Category: Radiology Authors: Chan Yoon, Moon Jong Chang, Chong Bum Chang, Jee Won Chai, Hyunseok Jeong, Min Kyu Song, Jae Hoon Shin, Seung-Baik Kang Tags: Original Article Source Type: research
Measurement of Trabecular Bone Score of the Spine by Low-Dose Imaging System (EOS ®): A Feasibility Study
Purpose/Introduction: Measurement of trabecular bone score (TBS ®) of the lumbar spine on dual energy X-ray absorptiometry (DXA) devices improves fracture risk prediction. We conducted a proof of concept study to assess the feasibility of TBS® measured on the low-dose imaging system EOS®. Methods: TBS was assessed on both DXA and EOS® in 122 patients aged ≥ 50 yr, receiving no anti-osteoporotic treatment. The TBS® was computed on full-body EOS® images, focusing on the lumbar spine region. The patients were also scanned with a DXA bone densitometer (Hologic) and the spine and hip bone mineral density (g/cm²) were c...
Source: Journal of Clinical Densitometry - August 14, 2018 Category: Radiology Authors: S. Kolta, A. Etcheto, J. Fechtenbaum, A. Feydy, C. Roux, K. Briot Tags: Original Article Source Type: research
Concurrent Assessment of Cartilage Morphology and Bone Microarchitecture in the Human Knee Using Contrast-Enhanced HR-pQCT Imaging
This study sought to develop and validate a novel joint imaging technique, contrast enhanced high resolution peripheral quantitative computed tomography (CEHR-pQCT), to concurrently assess bone microarchitecture and cartilage morphology in the whole human knee. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 14, 2018 Category: Radiology Authors: Geoffrey J. Michalak, Richard Walker, Steven K. Boyd Tags: Original Article Source Type: research
Lower Trabecular Bone Score is Associated With the Use of Proton Pump Inhibitors
Introduction: Trabecular bone score (TBS) provides indirect indices of trabecular microarchitecture and bone quality. Several studies have evaluated the influence of proton pump inhibitors (PPIs) on bone mass and geometric parameters, but no studies have evaluated the influence of PPIs on TBS. Methods: We reviewed the medical records of 1505 women aged 40 –89 yr who had bone mineral density (BMD) examinations as a part of the medical diagnosis and disease prevention program and who did not have osteoporotic fractures or conditions that could affect bone metabolism. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 9, 2018 Category: Radiology Authors: Young Ho Shin, Hyun Sik Gong, Goo Hyun Baek Tags: Original Article Source Type: research
Emerging Aspects of the Body Composition, Bone Marrow Adipose Tissue and Skeletal Phenotypes in Type 1 Diabetes Mellitus
Anthropomorphic measures among type 1 diabetic patients are changing as the obesity epidemic continues. Excess fat mass may impact bone density and ultimately fracture risk. We studied the interaction between bone and adipose tissue in type 1 diabetes subjects submitted to two different clinical managements: (I) conventional insulin therapy or (II) autologous nonmyeloablative hematopoietic stem-cell transplantation (AHST). The study comprised 3 groups matched by age, gender, height and weight: control (C = 24), type 1 diabetes (T1D = 23) and type 1 diabetes treated with AHST (T1D-AHST = 9). (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 9, 2018 Category: Radiology Authors: Adriana L. Carvalho, Bianca Massaro, Luciana T. P. e Silva, Carlos E.G. Salmon, Sandra Y. Fukada, Marcello H. Nogueira-Barbosa, Jorge Elias, Maria C.F. Freitas, Carlos E.B. Couri, Maria C. Oliveira, Belinda P. Sim ões, Clifford J. Rosen, Francisco J.A. d Tags: Original Article Source Type: research
Feasibility of Dual Energy X-Ray Absorptiometry Based Images for Measurement of Height, Sitting Height, and Leg Length in Children
Interpretation of pediatric bone mineral density by dual energy absorptiometry (DXA) requires adjustment for height (Ht). This is often not easily obtainable in nonambulant subjects. (Source: Journal of Clinical Densitometry)
Source: Journal of Clinical Densitometry - August 9, 2018 Category: Radiology Authors: N Capaldi, KT Kao, R MacDonald, KC Grainger, S Joseph, S Shepherd, A Mason, SC Wong Tags: Original Article Source Type: research
